The National Institutes of Health trial to evaluate the mpox (previously known as monkeypox) vaccine JYNNEOS has now entered the next stage and is studying the immune responses to and the safety of the vaccine in adolescents. The George Washington University is one of 18 clinical trial sites across the United States that have launched this stage testing the JYNNEOS vaccine.
Children with COVID-19 can be treated safely at home, helping to take the burden off the hospital system, according to a new study.
A recent Houston Methodist study may offer some guidance on when certain populations should get their next booster. A research team of computational medicine and data scientists from the Houston Methodist Research Institute predicted the immune response to COVID-19 vaccines with a math model they developed, and also found that current CDC dosing intervals may require customization to protect all individuals alike.
A panel of experts will hold a WCS media briefing on High Pathogenic Avian Influenza (HPAI) that is currently wreaking havoc around the world and is the largest known outbreak since scientists have begun tracking the disease.
A new study from Huntsman Cancer Institute shows HPV-related cancers are more common in young adults who previously had cancer. This data shows the importance of educating patients about the HPV vaccine – a safe and effective way to prevent cancer.
A cross-cultural comparison study is the first to investigate factors that influenced the decision to get the COVID-19 vaccine in an international sample of college students from the U.S., Israel and the Czech Republic. Results provide evidence of country-specific varying perceptions of susceptibly, severity, benefits and barriers associated with a virus and vaccine.
The dreaded tick-borne encephalitis (TBE) virus infects different types of brain cells in different parts of the brain, depending on whether the affected person's immune system is activated or not. This is shown in a new study at Umeå University, Sweden.
New research presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (Copenhagen, 15-18 April) and published in The Lancet Public Health shows that the impact of COVID-19 on mortality in people living with intellectual disabilities extended beyond deaths from the virus itself, and was linked with increased mortality in several other conditions.
A white-tailed deer afflicted with chronic wasting disease — also frequently referred to as “zombie deer disease” — will appear abnormally thin, move sluggishly, and salivate excessively. There is no cure: chronic wasting disease (CWD) is contagious and always fatal, and it has been detected with increasing frequency in Virginia and other states, raising concerns about effects on the deer population.
Hearing loss is a little known side effect of COVID-19, but a very real and frightening one. A University of South Australia nursing lecturer has now used her own experience to inform research worldwide, with her findings documented in the British Medical Journal.
In November 2022, the National Institute of Allergy and Infectious Diseases (NIAID) co-hosted a virtual workshop on the importance and challenges of developing mucosal vaccines for SARS-COV-2. The highlights of this workshop have now been published as a report in npj Vaccines.
New research led by the UNC Gillings School of Global Public Health shows that bivalent COVID-19 boosters are still providing effective protection from hospitalization and death, even against the most recent omicron subvariants.
UC San Diego Researchers describe for the first time how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body’s ability to suppress it.
A study led by scientists from Lankenau Institute for Medical Research (LIMR), part of Main Line Health, indicates vitamin D strengthens the lung lining, preventing COVID-19 as well as other viruses from penetrating the body’s airways to cause infection, and possibly also reducing fluid leakage into the airways, which causes pneumonia.
Every year, millions of people in the U.S. are diagnosed with sexually transmitted infections (STIs), which are infectious diseases spread through sexual contact. Infection rates are particularly high in young people, with half of new cases occurring in people between 15 and 24 years old.
Below are some of the latest headlines in the new Avian Flu channel on Newswise.
American College of Surgeons research published in JAMA Surgery reveals the complexities and variations that occurred in cancer reporting in the National Cancer Database (NCDB) because of the pandemic.
Omicron subvariants of SARS-CoV-2 — the virus behind COVID-19 — have shown an uncanny knack for evading antibodies produced either by vaccines or exposure to earlier versions of the virus, leading to many breakthrough infections. However, in order to sicken people, these viral variants must also avoid “killer” T cells, immune cells that are unleashed when the immune system detects foreign pathogens.
In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.
New research from RUSH University reveals pathways to reducing organ injury caused by severe COVID-19 infection. What began as a study of how the common cold affected patients with certain types of kidney disease evolved to mitigating myocarditis, liver injury and severe kidney injury from COVID-19.
The COVID-19 pandemic has had, and continues to have, profound impacts on the world. In the early stages of the pandemic, many countries adopted stringent countermeasures to limit the spread of the disease. These included extended lockdowns, particularly when medical care systems were pushed to the brink.
Researchers at Washington University School of Medicine in St. Louis have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines.
Pests and diseases may reduce global wheat yields by over 20%. A study published April 11th in the open access journal PLOS Biology by Sergio Latorre at University College London, UK and colleagues suggest that genomic surveillance may be an effective disease management tool with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines.
A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.
South Carolina residents were more hesitant than Americans as a whole to receive the COVID-19 vaccine during the fall of 2020, report researchers in the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina (MUSC) in the Journal of Psychiatry Research.
New research from Boston Medical Center found that alcohol screening rates dropped substantially during the first COVID-19 surge.
A new study’s finding that urban light pollution may disrupt the winter dormancy period for mosquitoes that transmit West Nile virus could be considered both good news and bad news: The disease-carrying pests may not survive the winter, or their dormancy period may simply be delayed.
People who avoid COVID-19 precautions to prevent illness are more likely to purchase firearms – a pattern of behavior most common among moderate and conservative individuals, according to a Rutgers study.
In this randomized clinical trial, anakinra did not prevent the need for mechanical ventilation or reduce mortality risk compared with standard of care alone among hospitalized patients with severe COVID-19 pneumonia. Future research should assess anakinra in patients with less severe pneumonia.
This national-level analysis found substantial adverse maternal outcomes among pregnant patients with COVID-19 infection at delivery during the early pandemic in the U.S. Specifically, the odds of severe respiratory complications were increased among pregnant patients with COVID-19 infection at delivery.
A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent. Their discovery could lead to more potent vaccines and new antibody-based treatments.
After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.
The U.S. experienced an unprecedented number of group A streptococcal infections in children from October to December of 2022, which should alert physicians to check for the potentially deadly infectious disease as the country moves out of the pandemic, according to research published by UTHealth Houston.
The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.
A group of physicians and scientists with the University of Miami Miller School of Medicine are releasing an important study that will be published in the journal Pediatrics on Thursday, showing that COVID-19 can cross into the placenta of pregnant women and cause brain injury in newborns, as evidenced with 2 cases they treated here in Miami. One of the infants also died at about 13 months old. Further testing of the infant’s brain specimen showed that the virus was still present in the brain at the time of death—which was over a year after birth.
Researchers have shown that, in two cases, COVID-19 infection breached the placenta and caused brain damage in the newborn.
Cleveland Clinic researchers found 41% of patients with long COVID, had moderate to severe sleep disturbances. The retrospective analysis also identified risk factors for moderate to severe sleep disturbances, including race, hospitalization for COVID-19, greater anxiety severity and fatigue. After adjusting for demographics, Black patients were three times more likely to develop these sleep disturbances. The findings were published in Journal of General Internal Medicine.
Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs. Increasingly, scientists are learning that organ dysfunction results from damage to the blood vessels, but why the virus causes this damage is unclear.
In a twist on the question, “Which came first, the chicken or the egg?”, scientists have long faced a similar question about how human adenovirus replicates: “Which comes first, assembly of the viral particle, or packaging of the viral genome?” Now, in a new study published today in Nature, researchers at Children’s Hospital of Philadelphia (CHOP) have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.
Recent study reveals neurodegenerative biomarkers after COVID-19, gives clues for monitoring and potential treatment of long COVID
The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies.
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