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Combining the anticancer drugs enfortumab vedotin and pembrolizumab (EV+P) led to significantly improved survival rates among patients with advanced urothelial cancer (the most common type of bladder cancer) compared with standard chemotherapy, according to results of a large international clinical trial involving 185 sites, including the Johns Hopkins Kimmel Cancer Center’s Greenberg Bladder Cancer Institute, in 25 countries.

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Tengteng Wang, PhD, MSPH, MBBS, cancer epidemiologist in the Section of Cancer Epidemiology and Health Outcomes at Rutgers Cancer Institute of New Jersey, has received more than $700,000 from the National Cancer Institute (R00CA267557) to support her research on examining the association between reproductive factors, gut microbiome, and benign breast disease (BBD).

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Researchers seeks to devise a way to detect lung cancers earlier and more accurately, increasing the likelihood that treatments can slow and cure the disease.

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An international interdisciplinary team of researchers, including Moffitt Cancer Center’s Tiffany Carson, Ph.D., has been selected to receive a Cancer Grand Challenges award.

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Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine have developed an algorithm to identify high-risk precancerous lesions on the fallopian tubes.

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Alex Jaeger, Ph.D., assistant member of the Molecular Oncology Department at Moffitt Cancer Center, has received a Damon Runyon-Rachleff Innovation Award. He is the first researcher in Florida and at Moffitt to earn this prestigious grant.

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Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. March is Colorectal Cancer Awareness Month, contact our media team to set up interviews.

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Endocrine Society members elected Carol Lange, Ph.D., of the University of Minnesota in Minneapolis, Minn., as its 2025-2026 President. She will serve as President-Elect for a year beginning in June 2024 before becoming President in June 2025.

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After spending more than three decades managing her diabetes, Pam Mirabile was alarmed by swelling in her foot. She visited Loyola Medicine podiatric surgeon Katherine Dux, DPM, who diagnosed her with Charcot foot, a rare complication of diabetes.

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Learn more from surgeon experts about the rise of colorectal cancer in younger adults.

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Rutgers Cancer Institute of New Jersey together with RWJBarnabas Health, the state’s leading cancer center and only Comprehensive Cancer Center as recognized by the National Cancer Institute (NCI), has scored in the “exceptional” range and was redesignated by the National Cancer Institute, placing it among the top cancer centers reviewed in 2023.

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Memorial Hermann Health System in Houston is now offering genoME®, a community health research program that, through genetic testing, can help a person determine how their genetic profile could impact their future health.

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Rebecca O’Brien turned scribbles on a notepad into an award-winning, one-woman show—and she never saw it coming. The unanticipated work of art helped her uncover the seed of humor after a stage 2 breast cancer diagnosis. Now, six years later, O’Brien—a survivor—wants to pay it forward.

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22 grants fund a range of innovative research and initiatives

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The Faculty of Medicine at Chulalongkorn University, cordially invites all those who are interested to attend the joint international conference on “CUTTING-EDGE NANOTECHNOLOGIES FOR GOOD HEALTH AND WELL-BEING” from July 9-12, 2024 between 8:00 and 18:00 hrs. at Chulalongkorn University and Mandarin Hotel, Bangkok, Thailand.

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Pool Cool is a program designed to educate young people in The University of Kansas Cancer Center’s catchment area on sun safety behaviors.

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Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues. UTSW received another $6 million for recruitment efforts.

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What if bacteria—which love to grow deep inside tumors—could guide cancer therapies directly to their target? A team of NIH-funded researchers has engineered a bacterial strain to “light up” tumors so that reprogrammed T cells, drawn like a moth to a flame, can find and destroy them. Their preclinical treatment could potentially be effective against any solid tumor type.

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People with cancer have different amounts of a type of repetitive DNA — called Alu elements — than people without cancer.

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Scientists at Washington University School of Medicine in St. Louis trained a machine-learning algorithm to predict accurately brain metastasis using biopsy samples from early-stage non-small cell lung cancer patients. It was also highly accurate in predicting those patients who do not develop metastatic brain tumors.

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Recent NCCN Guidelines updates—along with the supporting evidence—will be presented during the NCCN 2024 Annual Conference held in Orlando, Florida April 5-7, and simultaneously online. Visit NCCN.org/conference to learn more and register.

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Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth.

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SEATTLE — March 1, 2024 — Fred Hutchinson Cancer Center announced 12 recipients of the 2024 Harold M. Weintraub Graduate Student Award, which recognizes exceptional achievement in graduate studies in the biological sciences. This year’s recipients come from U.S. and international research institutions with thesis topics that include brain signals related to learning and emotion, bacterial pathogens and health, AI algorithms in rare disease diagnosis and treatment, and immune cells involved in brain tumors.

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Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi’s sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.

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Scaling back treatment can mean better quality of life for oropharynx cancer patients who qualify

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Experts at Rogel Cancer Center develop and study the impact of a new drug for salivary gland cancers

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Four University of Michigan research teams have made the bracket of 64 teams for STAT Madness, a virtual tournament of science. They were picked for their groundbreaking work on brain cancer, heart transplant, dementia care and deadly fungal infections published in 2023.

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Cancer researcher Miguel Reina-Campos, Ph.D., has joined the faculty of La Jolla Institute for Immunology (LJI) as an Assistant Professor to lead the Laboratory of Tissue Immune Networks. His laboratory at LJI aims to investigate the basis of CD8+ T cell tissue immunity to improve life-saving cancer immunotherapies.

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Children’s Hospital Los Angeles has received a multi-year $6 million award from the California Institute for Regenerative Medicine (CIRM) to develop innovative stem cell approaches to treat children and adolescents with recurrent solid tumors. The Cancer and Blood Disease Institute (CBDI) is a recognized leader in pediatric cancer care and research.

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A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for February 2024.

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A team at UC Davis has developed a machine-learning model that can better predict which patients are at greater risk to develop hepatocellular carcinoma.

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Howard S. Hochster, MD, FACP, director of the Gastrointestinal Oncology Program and Rutgers Cancer Institute of New Jersey Associate Director for Clinical Research and director of Oncology Research, RWJBarnabas Health shares his recommendations about keeping our attention focused on barriers to health care and preventive services and continuing to educate ourselves and others about colorectal cancer to reduce disparities.

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Colorectal cancer (CRC) is on the rise in young adults. Incidences of colorectal cancer in young people (those between their mid-20s and late 50s) has more than doubled since the 1990s. Howard S. Hochster, MD, FACP, director of the Gastrointestinal Oncology Program and Rutgers Cancer Institute of New Jersey Associate Director for Clinical Research and director of Oncology Research, RWJBarnabas Health, shares his thoughts on this trend.

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Researchers at the University of Michigan Health Rogel Cancer Center are exploiting a unique biological feature of glioblastoma to gain a better understanding of how this puzzling brain cancer develops and how to target new treatments against it. The team developed human and mouse models of glioblastoma oncostreams and examined multiple factors in the tumor microenvironment that could impact how oncostreams develop and how to reverse them.

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Gastrointestinal cancers were once diagnosed primarily by location. A tumor in the liver was liver cancer, while one in the pancreas was pancreatic. The few chemotherapy treatments available affected the entire patient—sometimes causing difficult side effects.

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Research on patient-centered treatment of head and neck cancers will be presented at the 2024 Multidisciplinary Head and Neck Cancers Symposium, which takes place in Phoenix and online today through March 2. Media registration is available. Studies recommended by symposium leadership for media are noted below, and outside experts are available to provide commentary.

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The recent Cancer Facts & Figures 2024 report from American Cancer Society (ACS) researchers revealed a stark increase in colorectal cancer (CRC) incidence among Americans under the age of 55. In just two decades, CRC has moved up from being the fourth leading cause of cancer death in both younger men and women, to first in men and second in women.

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In a groundbreaking medical procedure, researchers have utilized 5G communication technology to perform the world's first robot-assisted radical distal gastrectomy remotely without intraoperative or postoperative complications.

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Harvard Medical School scientists develop new CRISPR-based tool to study the immune function of genes. New gene-editing approach could optimize how scientists study the immune system’s role in cancer and other immune-mediated diseases.

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Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers.

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Cancers begin with abnormal changes in individual cells, and the ability to track the accumulation of mutations at the single-cell level can shed new light on the early stages of the disease

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A research project led by Lobelia Samavati, M.D., professor of internal medicine and molecular medicine and genetics at the Wayne State University School of Medicine, and supported by the National Institutes of Health (NIH), has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs. The tool, which uses a simple blood test, could allow for selective use of more invasive diagnostic tests often used to identify the disease.