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Breakthrough discovery is first report of a recombinant human biotherapeutic active against leukemic stem cells.

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Radiation-resistant leukemia cells can be killed by radiation after inhibition of a molecular target by a rationally-designed new drug.

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Dr. Eberich will lead the Biomedical Infomatics team as they apply the principles of computer science and information technology to biology and medicine to quickly move cutting-edge research into clinical use.

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J. Eric Bubbers, PhD, of the Saban Research Institute at Childrens Hospital Los Angeles, has received a $410,000 grant from Phase One Foundation. The award will fund a “first in childhood leukemia” multi-site study in children with relapsed or refractory acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML).

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Investigators at Childrens Hospital Los Angeles have found that unlike adults, levels of serum beta-natriuretic peptide (BNP) do not increase in pediatric trauma patients with serious head injuries.

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A type of white blood cell normally responsible for clearing bacteria from the blood is implicated.

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Affected children and adolescents who spend less time walking may be at increased risk for bone fractures and osteoporosis.

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Studies suggest role for IL-10 in prevention and treatment of potentially devastating neurological disease in newborns.

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Ophthalmologists examining infants for possible Shaken Baby Syndrome found that a handheld Spectral Domain Optical Coherence Tomography (SD-OCT) device provided high-resolution images of the retina and the vitreoretinal interface in infants with SBS, reports a study in the current issue of Retina, The Journal of Retinal and Vitreous Diseases.

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When a child develops red, watery eyes, it could be just allergies – or it may be the sign of a more serious eye condition, according to a leading pediatric ophthalmologist. Red, itchy, watery eyes can be a temporary allergic reaction to pollen and should go away after a few days or weeks. However, if your child has red, itchy eyes year-round or if their eyes become very sensitive to sunlight, it could be the sign of a more serious condition like atopic conjunctivitis.

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Diabetic retinopathy remains the major cause of blindness in adults under 60 in the U.S. The disease affects 5.3 million adults in the U.S. and some 24,000 of them go blind each year. Nearly sixty percent of all diabetes patients are expected to develop diabetic retinopathy within ten years of their diagnosis.

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Using a hand-held spectral domain optical coherence tomography (SD-OCT) imaging device, researchers have obtained high-resolution retinal scans of premature infants with progressive retinopathy of prematurity (ROP), according to a report in this month’s Archives of Ophthalmology.

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Infants as young as one-month-old are often prescribed contact lenses at pediatric eye surgery centers so their visual system will develop correctly. Infants may be fitted for contacts if they have had cataract surgery, need extremely high-strength prescription glasses, or have very different prescriptions for the two eyes.

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With the number of premature births and medically fragile infants now increasing in the U.S., a basic eye exam, including a red reflex test, should be given to all children shortly after birth. Unfortunately, some 75 percent of all children under five in the U.S. have never had a comprehensive eye exam, notes Angela Buffenn, M.D., M.P.H., Director of the Orbit and Eye Movement Institute at The Vision Center of Childrens Hospital Los Angeles and co-author of the report.

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Parents should take extra care in selecting toys for young children and supervising their play during the holidays, according to a leading eye surgeon.

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Many parents grew up with medical adages or advice that have since been proven by scientists to be incorrect or outdated. Here are five common myths about children’s eye health and the medical reality behind them, prepared by the physicians at The Vision Center at Childrens Hospital Los Angeles.

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A new drug delivery system that uses a tiny silicone cup sealed to the outer surface (episclera) of the eyeball may offer a more effective method for the delivery of medicines for retinal and vitreous diseases. The device, called an episcleral drug reservoir, holds the potential to fundamentally change the delivery of medications for diseases like macular degeneration, diabetic retinopathy, uveitis and retinoblastoma.

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Good vision can be directly correlated with a child's learning ability. As much as 80% of the learning a child does occurs through his eyes and approximately 1 in 4 school-age children have some type of vision impairment. Does your child have normal, healthy vision needed for classroom learning? Experts at The Vision Center at Childrens Hospital Los Angeles offer four tips for parents of school-age children.

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Dr. Jonathan C. Song, director of the Cornea Institute in The Vision Center at Childrens Hospital Los Angeles has just returned from a medical mission in which he worked with Syrian and Iraqi eye surgeons at the Syrian city of Dier Ezzor. During the medical mission, May 18-22, Dr. Song saw 50 patients and performed eight corneal transplants and five cataract surgeries. In addition to holding training sessions with Syrian ophthalmologists, he also lectured to 25 Syrian and Iraqi medical professionals about advanced eye surgery techniques.

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New research shows that children's eyes can be damaged from sun exposure, just like their skin. This damage may put them at increased risk of developing debilitating diseases such as cataracts or macular degeneration as adults. The experts at The Vision Center at Childrens Hospital of Los Angeles offer three tips for protecting young eyes at the beach and pool.