A new “armored” form of CAR T cell therapy may be able to help patients with non-Hodgkin lymphoma whose cancers do not respond to currently available CAR T cell therapies. The Phase I clinical trial was presented at the 2024 ASCO Annual Meeting.
Leading experts in transplant from Penn Medicine will converge in the Pennsylvania Convention Center in Philadelphia from June 1-5 for the American Transplant Congress. The event is the Joint Annual meeting of the American Society of Transplant Surgeons and the American Society of Transplantation.
Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.
Six hospitals in the University of Pennsylvania Health System (UPHS) earned perfect scores as part of Penn Medicine once again being named a 2024 LGBTQ+ Healthcare Equality Leader by the Human Rights Campaign (HRC) Foundation.
Researchers from Penn Medicine’s Abramson Cancer Center (ACC) and the Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in cancer research at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, happening May 31—June 4, 2024 in Chicago and online.
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models. The vaccine could potentially help manage the outbreak of the H5N1 virus currently circulating in birds and cattle in the United States, and prevent human infections with the virus.
In a trial analyzing how messages were framed in an underserved population, offering colorectal cancer screening options resulted in the highest screening rate
Researchers from the Gene Therapy Program (GTP) at the Perelman School of Medicine at the University of Pennsylvania will present ten research abstracts, two invited talks, and a workshop presentation highlighting their translational science and discovery research on gene therapy, gene editing, and adeno-associated virus (AAV) vector technology at the American Society of Cell and Gene Therapy (ASGCT) 27th Annual Meeting on May 7 - 11, 2024 in Baltimore, Maryland.
Mitchell Schnall, MD, PhD, has been appointed to a newly created role as Senior Vice President for Data and Technology Solutions for the University of Pennsylvania Health System (UPHS), following two terms as Chair of Radiology in Penn’s Perelman School of Medicine. In his new role, he will lead teams and projects that will pave a path for Penn Medicine to lead the health care industry into a new, technology- and data-driven era.
When one study says a treatment works, but another says it doesn’t (or worse), how are clinicians supposed to determine what they should do? A Penn Medicine team recently received funding from PCORI to build a guide system for these situations
In a public commitment to become the most environmentally friendly health care organization in the nation and lead the industry to reduce its outsized impact on climate change, Penn Medicine has signed the ambitious Health Sector Climate Pledge, promising to significantly cut and, eventually, eliminate its carbon emissions by 2042.
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania has found a big reason why.
Mitchell A. Lazar, M.D., Ph.D., the Rhoda and Willard Ware Professor in Diabetes and Metabolic Disease, and Director of the Institute for Diabetes, Obesity, and Metabolism in the Perelman School of Medicine at the University of Pennsylvania, is the 2025 recipient of the George M. Kober Medal from the Association of American Physicians (AAP). Lazar will receive the honor in Chicago at the AAP’s annual meeting which takes place April 25-27, 2025.
An educational video piloted by Penn Medicine’s Abramson Cancer and designed to reach diverse populations and address prostate cancer screening disparities helped increase knowledge and reduce uncertainty about screening.
Researchers from the Perelman School of Medicine at the University of Pennsylvania will present data on the latest research across the full spectrum of Neurology – including a link between head injury and suicide, potential traumatic brain injury biomarkers, a promising new drug to treat multiple sclerosis – at the American Academy of Neurology (AAN) Annual Meeting from April 13-18 in Denver, Colorado. Follow us on Twitter @PennMedicine and @PennMDForum for updates.
Researchers from the Abramson Cancer Center (ACC) and Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in cancer science and medicine at the American Association for Cancer Research (AACR) Annual Meeting 2024, taking place April 5-10 in San Diego, California.
DNA replication—which happens when cells divide—is one of the most important processes in all living organisms. In a landmark finding, published today in Cell, scientists identified a multi-protein “machine” in cells that helps govern the pausing or stopping of DNA replication to ensure its smooth progress.
Analysis found that models developed to detect depression using language in Facebook posts did not work when applied to Black people's accounts
For years, it was harder for Black patients to secure a coveted spot on the national kidney transplant waitlist because a clinical algorithm was making Black patients appear healthier than they were.
Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development.
On Friday, March 15, the Perelman School of Medicine (PSOM) at the University of Pennsylvania will celebrate Match Day, the annual event that reveals where graduating medical students will head for residency programs to further their training.
The University of Pennsylvania Perelman School of Medicine has received a $2.1M grant from PolyBio Research Foundation to expand long COVID research. The grant, issued via PolyBio’s Long COVID Research Consortium (LCRC), will support studies to characterize mechanisms of SARS-CoV-2 persistence in the gut, including determining the impact of viral reservoirs on gut microbiome ecosystems.
Through the use of artificial intelligence, teams hope to better check for diabetic retinopathy and improve the process of cervical cancer screenings
Black adults across the United States suffer from sleep problems following exposure to news about unarmed Black individuals killed by police during police encounters, according to new findings published today in JAMA Internal Medicine from researchers at the University of Pennsylvania Perelman School of Medicine.
A $5 million grant seeks to develop new, more efficient approaches to learn from the care delivered to patients across the University of Pennsylvania Health System and to train local scientists in the principles of “Learning Health System science.”
Buying personal hygiene supplies for people in need, helping them access fresh, healthy food, or offering rides to medical appointments may seem like simple acts of service.
Six physician-scientists from the University of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia have been elected to the American Society of Clinical Investigation, joining one of the nation’s oldest and most respected medical honor societies composed of more than 3,000 physician-scientists representing all medical specialties.
As we approach the four-year anniversary of the COVID-19 pandemic, health misinformation continues to be pervasive and negatively impact public health.
Analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma
An exhalation delivery system that uses a patient’s own breath to carry the anti-inflammatory compound fluticasone (EDS-FLU) directly to the sinuses reduced chronic sinus infection (sinusitis) symptoms and decreased aggravations and infections associated with chronic inflammation of the sinus by more than 50 percent, researchers from the Perelman School of Medicine at the University of Pennsylvania reported.
Ordering a palliative care consultation by “default” – via an automatic order programmed into the electronic medical record that doctors may cancel if they choose – is an effective strategy to give more hospitalized patients the opportunity to benefit from palliative care, and sooner, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.
The University of Pennsylvania Health System (UPHS) and Doylestown Health leaders announced plans today for the Bucks County health system to become part of Penn Medicine.
Advancements in the study of two rare heart conditions—peripartum cardiomyopathy (PPCM), and dilated cardiomyopathy (DCM)—contributed by researchers at the Perelman School of Medicine at the University of Pennsylvania may serve as critical guides in future work toward developing therapies for the conditions.
In a real-world setting, analysis showed that risk of infection and severe illness was significantly lower for those who were vaccinated against COVID-19, and cardiac conditions did not increase
A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation
Researchers developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
Researchers have found new disrupted genes and an unexpected molecular pattern—dubbed BREACHes—related to Fragile X Syndrome (FXS), a genetic disorder estimated by the Centers for Disease Control and Prevention to impact about 1 in 7,000 males about 1 in 11,000 females.
A “chaperone” molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer’s disease, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
By making mammograms easy to schedule through personal online patient portals, Penn Medicine saw a significant increase in screenings for breast cancer
For thousands of people around the world waiting for a kidney, paired exchange serves as a beacon of hope. One person's willingness to undergo the act of Kidney Paired Donation (KPD) often sets in motion a chain of beautiful and selfless acts, where individuals give and receive the chance for a better life.
Non-Hispanic Black patients with acute myeloid leukemia (AML) are living longer, now that new therapies are available, according to a study presented by researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine’s Abramson Cancer Center at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition (Abstract 955).
Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine’s Abramson Cancer Center.
The number of patients admitted with opioid use disorder (OUD) and injection-related infections who left the hospital before completing treatment increased significantly between 2016 and 2020 (from 9.3 percent to 17 percent) according to analysis from researchers at the Perelman School of Medicine at the University of Pennsylvania.
Lidocaine activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. Their findings, published today in Cell Reports, pave the way for a clinical trial to test the addition of lidocaine to the standard of care therapy for patients with head and neck cancers.
A tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression
A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right