Feature Channels: Vaccines

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A study from Ann & Robert H. Lurie Children’s Hospital of Chicago found that parents with children who were not yet vaccinated against COVID-19 were most likely to vaccinate their child after reading the following hypothetical scenario.

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A team of researchers at Los Alamos National Laboratory recently published the most comprehensive study of global COVID-19 variant transitions, which showed significant diversity in variant spread around the globe related to vaccination rates, number of co-circulating variants and immunity from previous infection.

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For millions of Americans that suffer from seasonal allergies (pollen and mold), climate change is exacerbating an earlier, longer, and overall worse allergy season.

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Researchers have used Argonne’s Advanced Photon Source to characterize a set of broadly neutralizing antibodies effective against a wide range of coronaviruses.

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A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for April 2023.

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Johns Hopkins Children’s Center researchers will present on numerous topics during the PAS 2023 meeting.

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Researchers reporting in ACS Central Science have now developed a system that directly targets and degrades the SARS-CoV-2 viral RNA genome, reducing infection in mice. The method could be adapted to fight off many viruses, as well as treat various diseases.

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Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

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Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.

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With the help of Argonne National Laboratory, Epstein-Barr Virus researchers identified a viral protein as a target for antiviral and vaccine development, as well as an antibody that might benefit the immunocompromised.

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The Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health will host its annual World Malaria Day Symposium Tuesday, April 25, from 8:30 a.m. to 5:45 p.m. EDT. The theme is the blood stage of malaria, which is the most devastating phase of the disease. The event will take place in person in Baltimore with thirteen panelists. A remote option is available to journalists.

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The National Institutes of Health trial to evaluate the mpox (previously known as monkeypox) vaccine JYNNEOS has now entered the next stage and is studying the immune responses to and the safety of the vaccine in adolescents. The George Washington University is one of 18 clinical trial sites across the United States that have launched this stage testing the JYNNEOS vaccine.

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A recent Houston Methodist study may offer some guidance on when certain populations should get their next booster. A research team of computational medicine and data scientists from the Houston Methodist Research Institute predicted the immune response to COVID-19 vaccines with a math model they developed, and also found that current CDC dosing intervals may require customization to protect all individuals alike.

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A new study from Huntsman Cancer Institute shows HPV-related cancers are more common in young adults who previously had cancer. This data shows the importance of educating patients about the HPV vaccine – a safe and effective way to prevent cancer.

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The immuno-oncology (IO) clinical trial landscape is shifting in new directions. While the number of total clinical trials is down, there are healthy signs of innovation.

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A cross-cultural comparison study is the first to investigate factors that influenced the decision to get the COVID-19 vaccine in an international sample of college students from the U.S., Israel and the Czech Republic. Results provide evidence of country-specific varying perceptions of susceptibly, severity, benefits and barriers associated with a virus and vaccine.

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Testing the efficacy of a vaccine candidate is typically a long process, with the immune response of an animal model taking around two months. A multi-institution team is developing a method that is more than an order of magnitude faster.

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Researchers reporting in ACS Central Science have developed a new testing platform that encapsulates B cells — some of the most important components of the immune system — into miniature “organoids” to make vaccine screening quicker and greatly reduce the number of animals needed for testing.

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Researchers at Washington University School of Medicine in St. Louis have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines.

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Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

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A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.

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May is Asthma and Allergy Awareness Month. Experts from the American College of Allergy, Asthma & Immunology caution that pollen season is starting earlier and lasting longer than in past decades.

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South Carolina residents were more hesitant than Americans as a whole to receive the COVID-19 vaccine during the fall of 2020, report researchers in the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina (MUSC) in the Journal of Psychiatry Research.

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After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.

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Read about cutting-edge cancer research centered around elephant genes, a new clinical trial, and grants to study vaccination hesitance in the Mountain West as well as chronic lymphocytic leukemia.

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A study by researchers at Washington University School of Medicine in St. Louis shows that vaccinating people with updated boosters as new variants of the virus that cause COVID-19 emerge could shore up population immunity even as the virus mutates, and thereby prevent another deadly COVID-19 wave.

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The seasonal flu vaccine is less effective in some years than others. New St. Jude research showed one reason behind this lack of efficacy is the inclusion of flu strains with an unstable viral protein.

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Recordings of media briefings will be posted by 10 a.m. Eastern Time on each day. Watch recorded media briefings at: www.acs.org/ACSSpring2023briefings.

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From septic shock to sticker shock. Keep up with this ever-growing, changing sector. Below are some of the latest stories on healthcare on Newswise.

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A team of scientists from the Renaissance School of Medicine (RSOM) at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

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Needles are an uncomfortable but necessary aspect of vaccination. But today, scientists report steps toward an alternative, relatively painless method that can deliver biological materials to cells by “shooting” them in with air. They will present their results at ACS Spring 2023.