Analysis of the first fully-sequenced genome of the Siberian hamster shows how these small, seasonal breeders adapt their bodies and energy usage to survive the winter. The study shows that shifting day length alone was enough to trigger these changes, regardless of temperature or how much food is available.
Research by neuroscientists at the University of Chicago shows how short-term, working memory uses networks of neurons differently depending on the complexity of the task at hand.
The new dedicated breast imaging suite in Orland Park will provide screening and diagnostic mammography as part of a joint venture with Solis Mammography.
Treatment with the drug olaparib significantly reduced the risk of disease progression or death from metastatic pancreatic cancer, according to findings from the recently completed, international, phase-III POLO (Pancreas cancer OLaparib Ongoing) trial.
In a tale of two epidemics, researchers from the University of Chicago and the University of Pittsburgh found that children of parents who use opioids have an increased risk of attempting suicide.
The University of Chicago Medicine earned its 15th “A” grade in hospital safety from the Leapfrog Group, making it one of just 41 health care providers across the country to have received consecutive top marks from the industry watchdog group.
A new therapy to re-engage the heart’s natural electrical pathways – instead of bypassing them – could mean more treatment options for heart failure patients who also suffer from electrical disturbances, such as arrhythmias, according to research led by the University of Chicago Medicine.
Brian Sinotte, FACHE, will be joining the University of Chicago Medicine as president of its Community Health and Hospital Division (CHHD) and of Ingalls Memorial Hospital, effective July 1, 2019.
Research by UChicago paleontologists finds that it is unlikely that a two-million-year-old, apelike fossil from South Africa is a direct ancestor of Homo, the genus to which modern-day humans belong.
Macrophages in adipose tissue (fat) link obesity to triple-negative breast cancer. Instead of fighting breast cancer, these immune cells actually promote it.
A systematic examination of the tumor and the tissue surrounding it — particularly normal cells in that tissue, called fibroblasts — has revealed a new treatment target that could potentially prevent the rapid dissemination and poor prognosis associated with high-grade serous carcinoma (HGSC), a tumor type that primarily originates in the fallopian tubes or ovaries and spreads throughout the abdominal cavity.
Following a national search, renowned physician-scientist Eric G. Pamer, MD, has been recruited to be the inaugural faculty director of the Duchossois Family Institute at the University of Chicago Medicine starting July 1.
A new study, published April 30, 2019 in Lancet Respiratory Medicine, is the first large investigation to examine the differences in genetic risk factors for childhood-onset and adult-onset asthma. This genome-wide association study found that childhood-onset asthma was associated with nearly three times as many genes as adult-onset asthma.
Continuing an ongoing effort to respond to the public health crisis of intentional violence, the University of Chicago Medicine and Advocate Christ Medical Center are joining forces to form Southland RISE (Resilience Initiative to Strengthen and Empower), a new collaborative designed to better care for individuals, families and communities on the South Side and south suburban communities.
A leading clinical and research psychologist at the University of Chicago Medicine has been awarded a $3.8 million grant from the National Institute of Alcohol Abuse and Alcoholism (NIAAA) — a division of the National Institutes of Health — to understand alcohol responses in individuals who have problems controlling their drinking.
The University of Chicago will lead the NRG Oncology Statistics and Data Management Center, which is receiving six more years of funding from the National Cancer Institute.
A unique approach that provides an ecosystem of trauma-informed care for children and their families who are critically injured or exposed to violence on the South Side of Chicago is getting a big boost, thanks to a $9.1 million gift to the University of Chicago Medicine by the Ellen & Ronald Block Family Foundation and the Hassenfeld Family Foundation.
A UChicago-based team working with collaborators in Bangladesh identified a new genetic variant linked to arsenic metabolism and toxicity.
A novel approach appears to be an effective alternative to immunosuppressive therapies for acute and chronic intestinal disease.
In a national survey, hospital pharmacy managers report a lack of advance notice, frequent drug shortages, hoarding and even rationing. Improving the supply of generic medications and creating novel strategies to manage scarce drugs is needed.
The American Association for Cancer Research honors Susan Cohn, MD, for her leadership in clinical trials to improve treatment and survival for neuroblastoma.
The University of Chicago Pritzker School of Medicine retained top rankings in the U.S. News & World Report annual review of the country’s top medical schools. Of the 120 accredited medical schools surveyed by U.S. News for its 2020 edition, Pritzker placed No. 16 (up from No. 18 last year) for research and No. 18 (up from No. 39) for primary care training.
A new study published in Nature Ecology and Evolution led by scientists from the University of Chicago challenges one of the classic assumptions about how new proteins evolve.
A new study from the University of Chicago Medicine shows African-American communities were the only racial/ethnic group to have consistent disparities in geographic access to trauma centers. A new Level 1 trauma center at UChicago Medicine, which opened in 2018, reduced those racial disparities in the city 7 fold.
Two older drugs, designed for other purposes, produced promising results in the treatment of mice with triple negative breast cancer.
Research published in the American Journal of Public Health shows CommunityRx helps patients gain confidence finding health resources in their own neighborhoods.
The University of Chicago Medicine has received re-certification by the QOPI Certification Program LLC, a wholly owned subsidiary of the American Society of Clinical Oncology, Inc.
New research by neuroscientists at the University of Chicago shows that as neurons process information about texture from the skin, they each respond differently to various features of a surface, creating a high-dimensional representation of texture in the brain.
Identifying molecular pathways that boost the immune response to tumor neoantigens opens up new ways to develop and amplify cancer immunotherapy.
Advancing Health Equity: Leading Care, Payment, and Systems Transformation is a national program to reduce and eliminate disparities in health care through innovative Medicaid payment and contracting models.
Ballmer Group, the philanthropic organization founded by Connie and Steve Ballmer, is giving $4.2 million to University of Chicago’s TMW Center for Early Learning + Public Health to fund its work that develops a model for a community-wide approach to promote cognitive and language development in young children.
Paleontologists at the University of Chicago have discovered the first detailed fossil of a hagfish, the slimy, eel-like carrion feeders of the ocean. The 100-million-year-old fossil helps answer questions about when these ancient, jawless fish branched off the evolutionary tree from the lineage that gave rise to modern-day jawed vertebrates, including bony fish and humans.
Multiple sclerosis is a demyelinating inflammatory disorder in which autoreactive T cells migrate into the central nervous tissue and damage oligodendrocytes and myelin, which protect nerve cells. Sephin1 prolongs a cytoprotective response in oligodendrocytes, protecting those cells and myelin from this inflammatory attack. It dampens central nervous system inflammation, limits myelin damage and reduces the reactivation of T cells.
New research from the University of Chicago shows that healthy infants have intestinal bacteria that prevent the development of food allergies.
Hospitals often prioritize patient testing and treatment over the restorative virtues of patient sleep. Frequent overnight awakenings, however, can cause complications. The SIESTA study found that a commitment to sleep-friendly routines and changes to the electronic health record system could reduce nighttime disruptions and improve the patient experience.
Two 29-year-old patients from Michigan and Illinois are recovering following back-to-back triple-organ transplants to replace their failing hearts, livers and kidneys, marking a first in U.S. health care history.
Working with nine animal models, researchers find a preference for stability over energy conservation during speed-related gait transitions.
In a new study published in Nature Communications, a team of scientists from UChicago demonstrated the application of tRNA sequencing to gut microbiome samples from mice that were fed either a low-fat or high-fat diet.
An international phase-2 trial of a CAR-T cell therapy—to be published on-line Dec. 1 in the New England Journal of Medicine (and presented at the ASH annual meeting in San Diego)—found that 52% of patients responded favorably to the therapy; 40% had a complete response and 12% had a partial response. One year later, 65% of those patients were relapse-free, including 79% of complete responders. The median progression-free survival “has not been reached.”
Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy. The medication, called AR101, is derived from peanut protein.
An analysis of Twitter data from the U.S. shows that social media usage largely mirrors daily work schedules and school calendars. The data reflect the amount of “social jet lag” caused when social demands make people wake up much earlier than their biological rhythms would prefer.
In the current issue of the Proceedings of the National Academy of Sciences, a team of physicians, geneticists and biologists describes a previously unknown genetic factor— a common non-coding sequence of DNA—that can either raise or reduce the risk of coronary artery disease or ischemic stroke.
Collaboration aims to improve outcomes for the community’s youngest children, from their first day of life
A new study by scientists from the University of Chicago shows how cyanobacteria, or bacteria that produce energy through photosynthesis like plants, change the way they grow and divide in response to different levels of light.
By combining the experimental anti-cancer antibody known as 5F9 with the anti-cancer antibody rituximab, researchers managing a phase 1b clinical trial were able to induce a positive response in 11 out of 22 people with relapsed/refractory non-Hodgkin’s lymphoma. Eight of the 22 patients went into complete remission from their cancers.
The $50,000 MacLean Center Prize in Clinical Ethics and Health Outcomes, the largest in clinical medical ethics, was awarded this year to Emory University's William Foege, MD, MPH.
In a new study published in Nature, scientists from the University of Chicago show how a common RNA modification plays an important role in the process of learning and memory formation.
ACCSIS-Chicago—led by University of Chicago cancer specialists Karen Kim, MD, MS, and Blase Polite, MD, MPP—has been awarded nearly $6 million over five years to test novel ways to improve CRC screening and follow-up among groups that have not been screened.
New research by scientists from the University of Chicago shows that just one gene controls whether a certain species of butterfly has white or yellow spots on its wings.
Nearly 120 million prescriptions for a thyroid medicine called levothyroxine are filled each year, but many patients with hypothyroidism never get the benefit. A new study pinpoints a consistent inherited mutation that prevents the only current treatment from doing its job.
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