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MRIs Link Impaired Brain Activity to Inability to Regulate Emotions in Autism

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Researchers found that – when it comes to the ability to regulate emotions – brain activity in autistic people is significantly different than brain activity in people without autism. Researchers showed that symptoms including tantrums, irritability, and anxiety have a biological, mechanistic basis.

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Social and Behavioral Sciences

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$3.9 Million Project Will Identify, Treat Washington State Toddlers at Risk for Autism

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A $3.9 million, five-year project in Washington state will identify and treat toddlers with autism in the critical years before age 3 - when specialized services can greatly improve their skills and behavior.

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Treatment Restores Sociability in Autism Mice Model

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UCLA researchers have treated mice that mimic human autism with a neuropeptide called oxytocin, and have found that it restores normal social behavior. In addition, the findings suggest that giving oxytocin as early as possible in the animal’s life leads to more lasting effects in adults and adolescents.

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Why Suramin, a Century-Old, Anti-Parasitic Drug May Hold the Key to Understanding Autism

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N of One: Autism Research Foundation's Founder, John Rodakis, has published an easy to read review and commentary on: “Antipurinergic therapy corrects the autism-like features of the Fragile X (Fmr1 knockout) mouse model”

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Century-Old Drug Reverses Autism-Like Symptoms in Fragile X Mouse Model

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Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study published in this week’s online issue of Molecular Autism, suggests that a genetic form of autism-like symptoms in mice are also corrected with the drug, even when treatment was started in young adult mice.

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Scientists Developing Imaging Test for Autism Spectrum Disorder

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Virginia Tech Carilion Research Institute scientists have designed a two-minute brain-imaging test that may be able to aid in the diagnosis of children with autism spectrum disorder.

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Diverse Autism Mutations Lead to Different Disease Outcomes

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People with autism have a wide range of symptoms, with no two people sharing the exact type and severity of behaviors. Now a large-scale analysis of hundreds of patients and nearly 1000 genes has started to uncover how diversity among traits can be traced to differences in patients’ genetic mutations.

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Machine Learning Reveals Unexpected Genetic Roots of Cancers, Autism and Other Disorders

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University of Toronto researchers from Engineering, Biology and Medicine teach computers to ‘read the human genome’ and rate likelihood of mutations causing disease, opening vast new possibilities for medicine

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Autism and Intellectual Disability Studied in Quest for New Treatment Approaches

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NIH-funded collaboration on treatments of rare genetic syndromes that could reveal a shared biology of autism spectrum disorders

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"Master Regulator" Gene — Long Tied to Autism Disorders — Can Stimulate Other Genes Involved in Early Brain Development

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Chemical modifications to DNA’s packaging — known as epigenetic changes — can activate or repress genes involved in autism spectrum disorders (ASDs) and early brain development, according to a new study to be published in the journal Nature on Dec. 18.