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Medicine

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immune system activation , donor-recipient matches , Innate Immune System, adaptive immune system, acquired immune system, SIRP-alpha , CD47, monocyte activation , Cell Biology, Molecular Biology, Transplantation

Experts Uncover First Molecular Events of Organ Rejection

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Researchers at the University of Pittsburgh and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ.

Medicine

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Heart, canadian first, Heart Failure, heart implant device, Treatment, Peter Munk Cardiac Centre, Ted Rogers Centre for Heart Research, University Health Network

First-in-Canada Implant of Novel Sensor Device for Heart Failure Patients

In a Canadian first, a medical team has implanted a wireless device inside a heart failure patient, permitting clinicians to monitor the patient’s cardiovascular status – virtually and in real-time – and proactively adjust treatment to prevent costly, potentially unnecessary hospitalization.

Medicine

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Joint Replacement, Hip Replacement, Knee Replacement, anti-rheumatic medication, Rheumatic Diseases, Hospital For Special Surgery, Arthroplasty, DMARDs

Expert Panel Publishes Guidelines for Medication Management in Rheumatic Disease Patients Having Joint Replacement

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In the first such collaboration of its kind, an expert panel of rheumatologists and orthopedic surgeons has developed guidelines for the management of anti-rheumatic medication in patients undergoing hip or knee replacement. The goal was to lower the risk of infection, which is linked to the use of the medications.

Medicine

Channels:

Hip Relplacement, Hip Replacement Surgery, Knee Replacement, Knee Replacement Surgery, Perioperative Management, periprosthetic joint infection, ACR guidelines

New Guideline Aims to Reduce Infections in Total Hip & Knee Replacement Patients

The joint guideline between ACR and AAHKS provides eight recommendations on preoperative management of total hip and knee replacements.

Medicine

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Northwestern University, Northwestern University Feinberg School of Medicine, Northwestern Medicine, Transplantation, lung transplanatation, Research

Hidden Immune Cells Cause Lung Transplant Failure

Scientists have discovered that a subset of immune cells called nonclassical monocytes (NCMs), previously unknown to reside in the lungs, play a key role in driving primary graft dysfunction (PGD), the leading cause of death after lung transplantation. The study demonstrates targeting these cells could lead to novel treatments for PGD, a complication that currently impacts more than half of transplant patients.

Medicine

Channels:

fecal transplant, Fecal Transplantation for Persistent C. difficile Infection, fecal microbiota transplantation, Microbiome, Microbiota, Metagenomics, Single nucleotide variants, Bioinformatics, C. Difficile, Bacteroides, HUman Microbiome Project, Colitis

Donor Microbes Persist Up to Two Years After a Fecal Transplant to Treat Recurrent C. difficile Infection

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UAB researchers have made the first direct demonstration that fecal donor microbes remained in recipients for months or years after a transplant to treat the diarrhea and colitis caused by recurrent Clostridium difficile infections.

Medicine

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Kidney Transplantation

Calculator Estimates Success of Kidney Transplants Involving Particular Donor-Recipient Pairs

• A new calculator estimates the likelihood that a given patient who receives a kidney transplant from a particular living donor will maintain a functioning kidney. • The calculator may be especially useful for kidney paired donation.

Life

Business

Law and Public Policy

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Transportation, Trump agenda, Trump, Infrastructure, public-private partnerships

Private Sector Hungry to Invest: Analyzing Trump's Infrastructure Agenda

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Medicine

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Stem Cell, regen med

UIC Launches Center for Stem Cell and Regenerative Medicine

The University of Illinois at Chicago College of Medicine will launch a new center that will focus on understanding tissue regeneration and pioneering future developments in stem cell biology as a means to repair diseased organs and tissues.

Business

Channels:

nanotechnnology, Nanomedicine, nan, Lamborghini, carbon fiber composites materials, implantable drug delivery, Implantable Device, Orthopedic Device

Houston Methodist, Automobili Lamborghini Join Forces to Study Implantable Medical Devices

Researchers from Houston Methodist and Italian super sports car maker Automobili Lamborghini are working together on new carbon fiber materials for implantable devices used in therapeutic drug delivery and orthopedics.







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