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Medicine

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antibiotic resisistance, Children's Hospitals, Length Of Stay, Bacterial Infections, Children's Health Care

'Super Bugs' Study Author Sharon Meropol, MD, PhD, Says a Seven-Fold Increase in Antibiotic-Resistant Bacteria Results in 20 Percent Longer Hospital Stays for Children

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Medicine

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Head And Neck Cancer, Immunotherapy, Immunotherapy Clinical Trials, head and neck squamous cell carcinoma

University Hospitals Seidman Cancer Center Enrolls First Patient in New National Head and Neck Cancer Study

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Story about the first patient enrolled in the new national phase I trial studying the side effects and best dose and schedule of pembrolizumab, an immunotherapy drug, when given together with chemotherapy and radiation therapy following surgery for very high risk head and neck cancer. Pembrolizumab is one of the first immunotherapy drugs.

Medicine

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lysosomal disease , Nature, Nature (magazine), Research, Genetics, Therapy, press release, news, Cincinnati Children's Hospital Medical Center, Pediatric, Children

Nature Study Suggests New Therapy for Gaucher Disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies. Reporting their data Feb. 22, the international research team conducted the study in mouse models of lysosomal storage disease and in cells from blood samples donated by people with Gaucher disease.

Medicine

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ProMedica, Healthgrades, ProMedica Toledo Hospital, Healthcare Quality

ProMedica Toledo Hospital Named One of Healthgrades 2017 America’s 100 Best Hospitals

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ProMedica Toledo Hospital is pleased to announce it has received the 2017 America’s 100 Best Hospitals AwardTM from Healthgrades, the leading online resource for comprehensive information about physicians and hospitals. For the third year in a row, ProMedica Toledo Hospital is among the top two percent of more than 4,500 hospitals nationwide for its clinical excellence.

Medicine

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Obesity, Diet, Inflammation, Mediterranean Diet, pain

Mediterranean Diet May Decrease Pain Associated with Obesity

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Eating a Mediterranean diet could decrease the chances an overweight person will experience regular pain, new research suggests.

Medicine

Life

Social and Behavioral Sciences

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Mindfulness, Meditation, yoga, Aging, Psychology

Mindfulness Shows Promise as We Age, but Study Results Are Mixed

As mindfulness practices rise in popularity and evidence of their worth continues to accumulate, those who work with aging populations are looking to use the techniques to boost cognitive, emotional and physiological health. But studies so far have shown mixed results in the elderly.

Medicine

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Cancer, math, Math Anxiety, Numeracy

Decision-Making Suffers When Cancer Patients Avoid Math

Many of the toughest decisions faced by cancer patients involve knowing how to use numbers -- calculating risks, evaluating treatment options and figuring odds of medication side effects. But for patients who aren’t good at math, decision science research can offer evidence-based advice on how to assess numeric information and ask the right questions to make informed choices.

Science

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scientific collaboration, Science Policy, International Collaboration

International Science Collaboration Growing at Astonishing Rate

Even those who follow science may be surprised by how quickly international collaboration in scientific studies is growing, according to new research. The number of multiple-author scientific papers with collaborators from more than one country more than doubled from 1990 to 2015, from 10 to 25 percent, one study found.

Medicine

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ProMedica, Social Determinants, health reform, Health Care, Health Care Acces, Affordable Care Act (ACA)

Op-Ed: Here's How to Reform Health Care

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Our nation’s health care system is a mess. The industry spends $3 trillion annually and constitutes more than 17 percent of the nation’s GDP. For patients and their families, shouldering the burden of rising health care costs often leads to financial hardship and is the No. 1 cause of personal bankruptcy. Escalating health care costs lead many to forgo care, or patch together payments while neglecting other basic needs.

Medicine

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Autism, Neurodevelopment Disabilities, Autism diagnosis

Max Wiznitzer, MD, Autism Expert, University Hospitals Rainbow Babies & Children's Hospital, Available for Comment on Nature Autism Study

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Max Wiznitzer, MD, has a longstanding interest in neurodevelopmental disabilities, including autism.

Medicine

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hemagtology, JCI Insight, Journal of Clinical Investigation, Histiocytosis, Langerhans, HLH, hemophagocytic lymphohistiocytosis, Cincinnati Children's Hospital Medical Center, press release, news, Research

Doctors Treat Deadly Cancerous Disorders with Gene-Guided, Targeted Therapy

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Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them. Researchers report their data in Journal of Clinical Investigation Insight (JCI Insight). They recommend the regular use of comprehensive genomic profiling at diagnosis to positively impact clinical care,

Science

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Ergonomics, Tattoo, Public Health, Musculoskeletal, Occupational Safety and Health

Being a Tattoo Artist Is a Pain in the Neck, Study Finds

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Getting a tattoo may hurt, but giving one is no picnic, either. That’s the finding of the first study ever to directly measure the physical stresses that lead to aches and pains in tattoo artists—workers who support a multibillion-dollar American industry, but who often don’t have access to workers’ compensation if they get injured.

Medicine

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Obgyn, Vulvar and vaginal atrophy, Estrogen Therapy, Female Sexual Health, Female Sexual Dysfunction, dyspareunia

High Rates of Satisfaction for Applicator-Free Local Estrogen Softgel Ovule in Post-Menopausal Women

A new investigational delivery method for localized vaginal estrogen therapy that utilizes an applicator free softgel to alleviate moderate-to-severe vaginal pain during intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), received high rates of patient satisfaction among post-menopausal women, according to post-trial survey results published in the journal Menopause. “These survey results show that something as simple as a change to a more elegant delivery system that is easier to use and not messy might empower more post-menopausal women to seek prescription treatment for VVA, and perhaps help them stay with the application guidelines for longer,” said study first author Sheryl Kingsberg, PhD, Division Chief, OB/GYN Behavioral Medicine, UH Cleveland Medical Center.

Science

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Oroville Dam, Flood, flood barriers, Flood Control

Oroville Crisis Exposes Need for Infrastructure Updates to Dam Spillways, Harkens Back to Johnstown, Pa. Catastrophe

Life

Education

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Teaching, Higher Education

Good Teaching: Where the Money Should Go

Considered as a whole, one finding stood out that may prompt institutions to reflect on their priorities. That finding: “Good teaching is the primary means through which institutions affect students.”

Medicine

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Pregnancy, Pregnant Women, Immunity, Immune Response, baby, Babies, Research, Ohio

Ohio State Study: Baby's Sex Plays a Role in Pregnant Woman's Immunity

Women have claimed for years that their bodies react differently whether they’re pregnant with a boy or girl. Now evidence, published by Ohio State University researchers shows the sex of a baby is associated with pregnant women’s immune responses.

Medicine

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Miller-Dieker Syndrome , Organoids

Human Brain ‘Organoids’ Offer New Insight Into Rare Developmental Disease

Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of Miller-Dieker Syndrome (MDS), a rare genetic disorder that causes fatal brain malformations

Medicine

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Neonatology, pulmonary biology, Lungs, Antibiotics, Infection, Science Translational Medicine , Cincinnati Children's Hospital Medical Center, Gut Bacteria, Pediatrics, news release distribution

Excessive Antibiotic Use in Newborns Can Permanently Damage Lungs’ Defenses

Doctors have long understood that antibiotics that protect infants from infection also can disrupt the normal growth of their gut bacteria. However, a new study reveals that the consequences of routine antibiotic use may be deeper and longer lasting than expected. The study, published Feb. 8 in Science Translational Medicine, shows that short-term disruption of gut bacteria makes infant mice more likely to develop pneumonia. It also makes them more likely to die from it.

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CWRU Researcher Discovers Fish Uses Sneaking Behavior as Stealth Mating Strategy

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A Case Western Reserve University researcher found and videoed the Cuatro Ciénegas cichlid, Herichthys minckleyi, using the reproductive strategy called sneaking to insert himself between a mating pair and pass his DNA onto the next generation.

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CWRU Researchers Secure $2m NIH Grant to Test Portable Sickle Cell Monitor

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Researchers at Case Western Reserve University will use a $2 million grant from the National Institutes of Health to develop and test a small, portable blood-adhesion monitor for sickle cell disease patients. They hope to make the device as useful as at-home insulin monitors diabetes patients use to manage their disease.







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