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Medicine

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Icahn Institute for Genomics and Multiscale Biology , Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Uconn, University of Connecticut

Team of Scientists Demonstrate Path for Tackling Rare Cancers with No Effective Treatment

Study results indicate importance of treatment based on genetic mutation rather than location of origin

Life

Education

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Asian American Students Have Strong Academic Support – but Is It Too Much?

Despite having the strongest academic support from parents, teachers, and friends, second-generation Asian American adolescents benefit much less from these supports than others, finds a study by NYU’s Steinhardt School of Culture, Education, and Human Development.

Medicine

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Psychiatric Disease, Mental Health, neurologic disease

A New Approach to Diagnosing Mental Disorders Could Become an Alternative to DSM-5

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A consortium of psychiatrists and psychologists from universities worldwide, co-led by Stony Brook University, University of Minnesota and University of Notre Dame, has proposed a new approach to diagnosing mental disorders.

Science

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Non-breeders, University of Vienna, Social Groups, Ravens, Cognitive Skills, Thomas Bugnyar, Cognitive Biology, Intelligence, scientific reports

Ravens: Non-Breeders Live in Highly Dynamic Social Groups

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Ravens have impressive cognitive skills when interacting with conspecifics – comparable to many primates, whose social intelligence has been related to their life in groups. An international collaboration of researchers led by Thomas Bugnyar, Professor at the Department of Cognitive Biology, University of Vienna, could uncover for the first time the group dynamics of non-breeding ravens. The results help to understand the evolution of intelligence in this species and were published in the scientific journal "Scientific Reports".

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Marine Protected Areas

Lack of Staffing, Funds Prevent Marine Protected Areas From Realizing Full Potential

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Marine protected areas (MPAs) are an increasingly popular strategy for protecting marine biodiversity, but a new global study demonstrates that widespread lack of personnel and funds are preventing MPAs from reaching their full potential. Only 9 percent of MPAs reported having adequate staff.

Medicine

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Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Epigenetics, heroin epidemic, Heroin, Heroin Addiction, histone deacetylase, hyperacetylation, Striatum, Glutamate, GRIA1, JQ1, Drug Addiction

Epigenetic Alteration a Promising New Drug Target for Heroin Use Disorder

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

Medicine

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Diabetic Retinopathy, Retinopathy Of Prematurity, Premature Babies, Diabetes, Angiogenesis, Lucentis, Eylea, Ranibizumab, aflibercept, Drug Discovery

Study Suggests New Way to Prevent Vision Loss in Diabetics and Premature Babies

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Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice. The study, “Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy,” which will be published March 22 in The Journal of Experimental Medicine, suggests that inhibiting this molecule may prevent similarly aberrant blood vessels from damaging the vision of not only diabetics, but also premature infants.

Science

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Metals, DNA, metal-containing drugs , Drugs, Cancer, Molecular Mechanisms, chemotherapeutic, Agents, Leticia González , University of Vienna, Jacinto Sá, Uppsala University , Interact

How Do Metals Interact with DNA?

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Since a couple of decades, metal-containing drugs have been successfully used to fight against certain types of cancer. The lack of knowledge about the underlying molecular mechanisms slows down the search for new and more efficient chemotherapeutic agents. An international team of scientists, led by Leticia González from the University of Vienna and Jacinto Sá from the Uppsala University, have developed a protocol that is able to detect how metal-based drugs interact with DNA.

Medicine

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New Software Tool Powers Up Genomic Research

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A group of computational biological researchers, led by Stony Brook University’s Rob Patro, an Assistant Professor in the Department of Computer Science in the College of Engineering and Applied Sciences, has developed a new software tool, Salmon — a lightweight method to provide fast and bias-aware quantification from RNA-sequencing reads. The research was published in the March 6 edition of Nature Methods. .

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Coral Bleaching Ready for Crowdsourcing Solution

Savvy divers with just a pencil and an underwater slate can now participate in a WCS-led initiative to record coral bleaching observations around the world.







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