Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer’s disease (AD) therapy.
Researchers at the Francis Crick Institute, UCL and MSD have identified a potential treatment target for a genetic type of epilepsy. Developmental and epileptic encephalopathies are rare types of epilepsy which start in early childhood. One of the most common types of genetic epilepsy, CDKL5 deficiency disorder (CDD), causes seizures and impaired development.
Researchers at Linköping University, Sweden, have examined the brains of 16 patients previously hospitalised for COVID-19 with persisting symptoms. They have found differences in brain tissue structure between patients with persisting symptoms after COVID-19 and healthy people. Their findings, published in the journal Brain Communications, can bring insights into the underlying mechanisms of persisting neurological problems after COVID-19.
A woman who never developed Alzheimer's despite a strong genetic predisposition may hold the key to stopping the disease in its tracks.
تقوم أجسامنا كل يوم ببعض الأمور الغريبة وغير المعتادة. فيما يلي بعض الأسئلة والأجوبة التي تقدم التفسير العلمي وراء حدوث ذلك.
Australian researchers have flagged potential concerns over the use of social chatbots, calling for more studies into the impact of the AI software on neurodiverse people and those who find human interaction difficult.
In a new study, published online December 8, 2023 in Cell Reports, researchers at Sanford Burnham Prebys, with collaborators elsewhere, describe a novel molecular link between vitamin B12 and MS that takes place in astrocytes – important non-neuronal glial cells in the brain.
A diario, el cuerpo hace algunas cosas bastante extrañas e inusuales. A continuación, se incluyen algunas preguntas y respuestas que ofrecen la explicación científica de por qué suceden.
Todos os dias, nossos organismos reagem de formas peculiares e incomuns. Aqui estão algumas perguntas e respostas que explicam a base científica desses eventos.
Press registration is now open for journalists who wish to attend the 76th Annual Meeting of the American Academy of Neurology (AAN). The 2024 AAN Annual Meeting will be held from April 13-18 in a hybrid format offering the option to participate in person in Denver or live online.
University of California, Irvine, researchers discovered a mechanism that controls the identity of stem cells. When this mechanism fails, embryonic stem cells revert back in time and become totipotent.
Published in the 2023 Volume 3 issue of Psychoradiology a team of dedicated researchers from The University of Hong Kong and The University of Electronic Science and Technology of China has conclusively identified the right inferior frontal gyrus (rIFG) as a key input and causal regulator within the subcortical response inhibition nodes
UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.
Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease.
The involvement of specific basal ganglia-thalamocortical circuits in response inhibition has been extensively mapped in animal models, but the critical nodes and directed causal regulation within this inhibitory circuit in humans have remained controversial.
The recipient of the Research to Prevent Blindness / David Epstein Career Advancement Award in Glaucoma Research sponsored by Alcon is Alex Huang, MD, PhD, Associate Professor of Ophthalmology at the UC San Diego School of Medicine.
Computational neuroscientist probes how the brain learns, remembers, and decides
Most people with schizophrenia have extensive impairment of memory, including prospective memory, which is the ability to remember to perform future activities.
New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood. Thinning of the orbitofrontal cortex, a region in the brain that affects emotion, during adolescence was also associated with increased depressive symptoms later in life.
The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of long-term, brain-related disease, according to a new study.
Researchers at the University of Central Florida College of Medicine (UCF COM) in Orlando, Florida completed research that is very promising in the treatment of Parkinson's disease
What happens in the brain to cause many neurodevelopmental disorders, including autism spectrum disorder (ASD), remains a mystery.
For 30 years, Cheryl Rosenfeld has studied how biological information gets transferred from mothers to babies during pregnancy.
James Boland, an acoustician for SLR Consulting, employed insights from the field of sensory criminology to better understand the unique acoustic needs inside prison environments. By focusing on speech intelligibility, strategic reduction of noise levels, and the incorporation of privacy considerations, acoustic design can significantly improve the overall prison environment. Creating distinct zones within the prison and balancing moments of quiet with activity are essential to fostering a more comfortable and secure space.
Aggression is often associated as a negative emotion. Uncontrolled aggression can lead to conflict, violence and negative consequences for individuals and society. Yet that does not that mean that aggression serves no purpose. It is an instinctive behavior found in many species that may be necessary for survival. The key is managing and channeling aggression.
Mice typically live two years and monkeys live 25 years, but the brains of both appear to develop their synapses at the same time. This finding, published in a recent study led by neuroscientist Bobby Kasthuri of the U.S. Department of Energy’s (DOE) Argonne National Laboratory and his colleagues at the University of Chicago, is a shock for neuroscientists.
In some diseases, the underlying processes can start years before a diagnosis is made. A new study finds that people who later develop multiple sclerosis (MS) are more likely to have conditions like depression, constipation and urinary tract infections five years before their MS diagnosis than people who do not develop MS.
What happens in the brain to cause many neurodevelopmental disorders, including autism spectrum disorder (ASD), remains a mystery. A major limitation for researchers is the lack of biomarkers, or objective biological outputs, for these disorders, and in the case of ASD, for specific subtypes of disease.
In this study of 2,574 participants with obstructive sleep apnea, compared with participants with objective sleep duration of at least seven hours, those sleeping less than seven hours had higher risks of all-cause mortality independent of apnea-hypopnea index. Further studies would be needed to investigate health benefits of extending sleep length among people with obstructive sleep apnea with short sleep duration.
With the approval of the State Council of Higher Education for Virginia, the Virginia Tech Carilion School of Medicine (VTCSOM) has established a Department of Neurosurgery.
In a detailed study, Diet’s Role in Modifying Risk of Alzheimer’s Disease: History and Present Understanding published in the Journal of Alzheimer’s Disease, we can finally see which diets are helpful in reducing the risk of developing Alzheimer’s disease.
A new paper in Innovation in Aging, published by Oxford University Press, shows that a great deal of media coverage of the actor Bruce Willis’ condition, frontotemporal degeneration, was inaccurate, revealing the public’s limited knowledge of the disease.
A new survey from the American Academy of Sleep Medicine reveals that 91% of Americans have lost sleep to binge-watch TV, and 75% have lost sleep due to online shopping.
The 30th annual conference "The Science of Consciousness" will be held at the Loews Ventana Canyon Resort in Tucson, Arizona from April 22-27, 2024.
Researchers have designed a lightweight helmet with tiny LEGO-size sensors that scan the brain while a person moves. The helmet is the first of its kind to accurately record magnetic fields generated by brain activity while people are in motion, reports a new research paper published in NeuroImage.
A new study from researchers at Wake Forest University School of Medicine shows that dopamine release in the human brain plays a crucial role in encoding both reward and punishment prediction errors.
Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools previously developed to analyze brains of patients in the clinic to investigate Alzheimer's disease progression in preclinical animal models.
Announcement of contents of the December 2023 issue of Neurosurgical Focus
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy. “Communication between nerve cells in large parts of the brain changes after a stroke and we show that it can be partially restored with the treatment”, says Tadeusz Wieloch, senior professor of neurobiology at Lund University in Sweden.
University of Virginia School of Medicine researchers have discovered how Lactobacillus, a bacterium found in fermented foods and yogurt, helps the body manage stress and may help prevent depression and anxiety.
Adding a modular chimeric cytokine receptor to CAR T cells increased their efficacy. Learn how this modular system could improve brain and solid tumor therapy.
Five FAU Ph.D. students, whose work embraces computational neuroscience, have been selected to receive the fellowships.
People with epilepsy have slow waves in their brains that may protect them from seizures.
A first-line therapy for obsessive-compulsive disorder (OCD) reshapes connectivity of the brain, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.
For many people with migraine, it can be difficult to find a treatment that is effective and reliable, and information on how medications compare to one another is lacking. A new study draws data from nearly 300,000 people using a smartphone app to help people make decisions about their medications. The study found that certain migraine medications like triptans, ergots and anti-emetics may be two to five times more effective than ibuprofen for treating migraine attacks, according to new research published in the November 29, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A study of post-9/11 veterans shows that those with moderate or severe traumatic brain injury (TBI) who have never been deployed have a higher risk of epilepsy than those who have been deployed. The study is published in the November 29, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The latest articles on occupational medicine, workplace culture, and the labor market are in the "In the Workplace" channel on Newswise.
Researchers at UHN's Krembil Brain Institute have uncovered links between structural changes in the brain and neuropsychiatric symptoms of various neurodegenerative diseases.
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