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Newswise: Scientists use tardigrade proteins for human health breakthrough
Released: 20-Mar-2023 7:00 PM EDT
Scientists use tardigrade proteins for human health breakthrough
University of Wyoming

University of Wyoming researchers’ study of how microscopic creatures called tardigrades survive extreme conditions has led to a major breakthrough that could eventually make life-saving treatments available to people where refrigeration isn’t possible.

Released: 20-Mar-2023 11:05 AM EDT
Mayo Clinic cancer expert highlights advancements in treating multiple myeloma
Mayo Clinic

March is Myeloma Awareness Month, and Sikander Ailawadhi, M.D., hematologist/oncologist at Mayo Clinic Comprehensive Cancer Center, shares details about new advancements in research leading to better outcomes for patients with multiple myeloma.

Released: 20-Mar-2023 9:00 AM EDT
Antibiotic resistance is an increasing problem. Learn all about it in the Drug Resistance channel.
Newswise

Staphylococcus aureus, Clostridioides difficile, Candida auris, Drug-resistant Shigella. These bacteria not only have difficult names to pronounce, but they are also difficult to fight off. These bacteria may infect humans and animals, and the infections they cause are harder to treat than those caused by non-resistant bacteria. Antimicrobial resistance is an urgent global public health threat.

     
Newswise: How Are Multiple Sclerosis and Hardening of the Arteries (Atherosclerosis) Linked?
Released: 17-Mar-2023 11:05 AM EDT
How Are Multiple Sclerosis and Hardening of the Arteries (Atherosclerosis) Linked?
Ochsner Health

While the scleroses are of inherently different composition and cause, and the prevalence of each types of scleroses is not breaking news, their linkage is beginning to make headlines with the emergence of new research.

Released: 16-Mar-2023 2:30 PM EDT
New Trials Show Promising, Minimally Invasive Procedure to Treat Resistant Hypertension
Ochsner Health

A recent study published in JAMA demonstrates the effectiveness of a procedure done under the skin, similar to placing a stent, to treat uncontrolled hypertension, or blood pressure that cannot be controlled despite the use of blood pressure control drugs and agents.

Released: 16-Mar-2023 10:10 AM EDT
Short night-time sleep linked with nearly doubled risk of clogged leg arteries
European Society of Cardiology

Sleeping less than five hours a night is associated with a 74% raised likelihood of developing peripheral artery disease (PAD) compared with seven to eight hours.

Newswise: Vitamin A may reduce pancreatitis risk during ALL treatment
Released: 15-Mar-2023 6:20 PM EDT
Vitamin A may reduce pancreatitis risk during ALL treatment
Cincinnati Children's Hospital Medical Center

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

Released: 15-Mar-2023 3:45 PM EDT
Don't keep hitting that snooze button! Get the latest research news and expert commentary on sleep here.
Newswise

It's sleep awareness week, according to the National Sleep Foundation. It’s important to understand how sleep deprivation can impact your health. Most people recognize that if they don’t get enough sleep, their mood and memory will suffer the next day.

       
14-Mar-2023 12:00 PM EDT
Targeting menin induces responses in acute leukemias with KMT2A rearrangements or NPM1 mutations
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center showed that inhibiting menin with revumenib, previously known as SNDX-5613, yielded encouraging responses for advanced acute leukemias with KMT2A rearrangements or mutant NPM1. Findings from the Phase I AUGMENT-101 trial were published today in Nature.

Released: 14-Mar-2023 7:00 AM EDT
Diuretics Work Differently According to Biological Sex and Time of Treatment
American Physiological Society (APS)

A new computational study in a mouse model finds biological sex and time of day makes a difference in the effectiveness of diuretics—medications commonly prescribed to manage high blood pressure. The study is published ahead of print in the American Journal of Physiology-Renal Physiology.

Released: 13-Mar-2023 6:35 PM EDT
Remote blood pressure management program enhanced care during pandemic
Mass General Brigham

New research has found that a remote hypertension program, operated by Mass General Brigham since 2019, successfully supported patients through the pandemic in achieving their blood pressure goals, with patients who enrolled during the pandemic reaching and maintaining their goal blood pressures an average of two months earlier than in the pre-pandemic period.

Released: 13-Mar-2023 3:05 PM EDT
Epilepsy could become easier to pinpoint with blood test
Lund University

Researchers from Lund University in Sweden have discovered higher levels of immune proteins in the blood before and after an epileptic seizure. The possible biomarkers can be identified using a simple blood test.

Released: 9-Mar-2023 4:00 PM EST
McMaster University researchers trial potential hemophilia treatment
McMaster University

The trial, which concluded in 2021, found that 133 hemophilia patients treated weekly with injections of efanesoctocog alfafor a year improved their outcomes and quality of life compared to their previous treatment.

Newswise: PCORI Awards Researchers $10.2 Million to Study Individualized Model of Hemodialysis
Released: 9-Mar-2023 10:05 AM EST
PCORI Awards Researchers $10.2 Million to Study Individualized Model of Hemodialysis
Wake Forest University School of Medicine

The Patient-Centered Outcomes Research Institute (PCORI) recently awarded researchers at Wake Forest University School of Medicine $10.2 million to study the effectiveness of an individualized model of hemodialysis, a procedure in which the blood is cleaned by a dialysis machine. The project is a collaboration between the School of Medicine, the Renal Research Institute and other health care systems across the country.

Released: 8-Mar-2023 12:00 PM EST
MD Anderson Research Highlights for March 8, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 8-Mar-2023 9:00 AM EST
Seeking leukemia’s Achilles heel
American Society for Biochemistry and Molecular Biology (ASBMB)

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells. The authors published their results on Jan. 19 in the journal Molecular & Cellular Proteomics.

Newswise: How does the immune system react to altered gravity?
Released: 7-Mar-2023 5:25 PM EST
How does the immune system react to altered gravity?
University of Barcelona

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

   
Released: 7-Mar-2023 2:10 PM EST
Scientists discover new lead in hunt for myeloma drug
eLife

A molecule involved in fat transport and metabolism is key to the progression of the malignant blood cancer multiple myeloma, researchers report today in eLife.

Newswise: Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia
Released: 7-Mar-2023 12:30 PM EST
Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia
University of California San Diego

UC San Diego researchers delve deep into the unknown cause of pediatric acute myeloid leukemia to identify a gene splicing dysregulation and potential target for treating the disease, which often becomes treatment-resistant.

Released: 7-Mar-2023 9:30 AM EST
Algorithm predicts females have higher risk for kidney damage after aneurysm repair
Michigan Medicine - University of Michigan

When receiving treatment for abdominal aortic aneurysm, female patients have a higher risk for kidney damage after endovascular repair, a study finds. Investigators also found that those with kidney disease and larger aneurysms had higher odds of developing acute injury after repair.

Newswise: Possible treatment strategy identified for bone marrow failure syndrome
28-Feb-2023 5:40 PM EST
Possible treatment strategy identified for bone marrow failure syndrome
Washington University in St. Louis

Research led by Washington University School of Medicine in St. Louis has identified a possible treatment strategy for a rare bone marrow failure syndrome that is named poikiloderma with neutropenia. The work also may have implications for treating other bone marrow failure syndromes with similar underlying dysfunctions.

Released: 2-Mar-2023 1:10 PM EST
Youth overweight a risk factor for blood clots as adult
University of Gothenburg

Being overweight in childhood and in early adulthood are discrete risk factors for blood clots later in life, a University of Gothenburg study shows.

Newswise: Cleveland Researchers Reveal How Oxygen is Delivered to Tissues, Open Door to New Class of Drugs
Released: 1-Mar-2023 10:05 AM EST
Cleveland Researchers Reveal How Oxygen is Delivered to Tissues, Open Door to New Class of Drugs
University Hospitals Cleveland Medical Center

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others. The breakthrough follows a landmark discovery from investigators at Harrington Discovery Institute at University Hospitals (UH) and Case Western Reserve University School of Medicine. The research team showed that a modified version of hemoglobin, termed S-nitrosohemoglobin, senses areas with insufficient oxygen, and then restores blood flow for oxygenation. The study recently published in PNAS.

Released: 27-Feb-2023 2:45 PM EST
New technology to improve cancer detection and treatment
University of Technology, Sydney

Researchers from the University of Technology Sydney have developed a new device that can detect and analyse cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress.

Newswise: How a New Blood-Vessel-on-a-Chip Can Help Researchers Further Understand Vascular Malformations
Released: 24-Feb-2023 1:40 PM EST
How a New Blood-Vessel-on-a-Chip Can Help Researchers Further Understand Vascular Malformations
University of North Carolina Health Care System

Vascular malformations (VMs), a group of rare genetic disorders that causes an abnormal formation of veins, arteries, capillaries, or lymphatic vessels at birth, can interfere with the duties of our circulatory system by causing blockages, poor drainage, and the formation of cysts and tangles.

Newswise: The Molecular Mechanism Behind Abdominal Aneurysms
Released: 23-Feb-2023 10:05 AM EST
The Molecular Mechanism Behind Abdominal Aneurysms
University of Maryland School of Medicine

In a new study using mice, University of Maryland School of Medicine researchers were able to tease apart the molecular components involved in abdominal aneurysms to better understand how and why they form.

Newswise: University of Vermont Cancer Center to Offer Innovative New Cancer Treatment
Released: 23-Feb-2023 9:50 AM EST
University of Vermont Cancer Center to Offer Innovative New Cancer Treatment
University of Vermont

The University of Vermont Cancer Center will offer a novel, highly effective form of cancer treatment called CAR T-cell therapy beginning in February. The Cancer Center will be the only healthcare institution in Vermont and northern New York to provide the treatment.

21-Feb-2023 7:00 AM EST
Researchers identify biomarker for diagnosing vascular dementia
University of California, Los Angeles (UCLA), Health Sciences

Patients with higher levels of a key molecule involved in the formation of new blood vessels were more likely to have cognitive impairment or evidence of brain injury, a consortium of academic medical centers reported.

Newswise: Cancer: In Italy every year over 8000 patients candidate for liquid biopsy
Released: 21-Feb-2023 10:10 PM EST
Cancer: In Italy every year over 8000 patients candidate for liquid biopsy
Sbarro Health Research Organization (SHRO)

SHRO Founder Antonio Giordano contributes to a new publication on the use of liquid biopsy to assess the treatment response and find mutations that confer resistance to cancer therapies.

Released: 21-Feb-2023 4:45 PM EST
Does living along the US-Mexico border affect the chances of survival among children with leukemia?
Wiley

Residing in border regions was linked with a higher risk of dying within five years among children with acute lymphoblastic leukemia, the most common type of pediatric cancer.

Released: 21-Feb-2023 2:05 PM EST
A New Catalyst For Recycling Plastic, New Antioxidants Found In Meat, And Other Chemical Research News
Newswise

Below are some of the latest articles that have been added to the Chemistry news channel on Newswise.

Newswise:Video Embedded rna-rescue-challenge-invites-players-to-solve-puzzles-and-advance-rna-therapeutics
VIDEO
Released: 21-Feb-2023 11:35 AM EST
RNA Rescue challenge invites players to solve puzzles and advance RNA therapeutics
University of California, Santa Cruz

Researchers at UC Santa Cruz working to develop novel RNA-based medicines are teaming up with a new group of collaborators—players of the online game Eterna. The

Not for public release

This news release is embargoed until 20-Feb-2023 5:00 PM EST Released to reporters: 14-Feb-2023 2:00 PM EST

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Released: 17-Feb-2023 5:25 PM EST
Daily rhythm detected for cerebral blood flow in stroke patients
Brigham and Women’s Hospital

Strokes are a leading cause of morbidity and mortality in the United States, as well as around the world. Various environmental and biological factors are known to affect the risks and outcomes of strokes.

Released: 16-Feb-2023 3:15 PM EST
Socioeconomic disparities in operation and survival rates for abdominal aortic aneurysm, new study finds
University of Sheffield

A new study from the University of Sheffield has found clear evidence of socioeconomic disparities in operation rates and survival after surgery for dangerous abdominal aortic aneurysm.

Released: 14-Feb-2023 2:50 PM EST
Multiplication on, multiplication off: Targeting an enzymatic switch to develop oncology drugs
University of Illinois Urbana-Champaign

Interdisciplinary research highlighted lipid-protein interaction as a new avenue for oncology drug development, demonstrating its functionality by designing small molecule-based inhibitors to target acute myeloid leukemia.

Released: 10-Feb-2023 1:05 PM EST
D-dimer blood test shows value in detecting prosthetic joint infections
Wolters Kluwer Health: Lippincott

Measurement of plasma D-dimer levels – a test more commonly used to detect blood-clotting disorders – can provide useful information when making the difficult diagnosis of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Released: 10-Feb-2023 12:05 PM EST
Coconut Sugar May Lower Blood Pressure, Artery Stiffness in Older Adults
American Physiological Society (APS)

A first-of-its-kind study finds a natural coconut sugar may help reduce the risk of cardiovascular disease by improving blood vessel health and managing high blood pressure. The study is published ahead of print in the Journal of Applied Physiology.

Released: 8-Feb-2023 4:55 PM EST
Fine particles in the air associated with higher blood pressure in London teens
King's College London

A study of adolescents aged 11-16 in London has found long-term exposure to PM2.5 is associated with higher blood pressure, with stronger associations seen in girls.

Released: 7-Feb-2023 4:05 PM EST
Drug combination shows potential in aggressive leukemia
Virginia Commonwealth University (VCU)

Acute myeloid leukemia (AML) is an aggressive form of cancer that originates in the bone marrow, rapidly spreads to the blood and can quickly cause death if not treated promptly. Despite recent therapeutic advances, it continues to be associated with poor outcomes in the majority of patients with this disease.

Newswise: Researchers zero in on potential new function of lymphatic system: producing blood
Released: 6-Feb-2023 8:05 AM EST
Researchers zero in on potential new function of lymphatic system: producing blood
University of South Australia

Scientists investigating the causes of lymphoedema have made a major discovery, revealing that lymphatic vessels can produce red and white blood cells.

Newswise: New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Released: 2-Feb-2023 1:10 PM EST
New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it. Their analysis, using a large national administrative database with records for pregnant people with SCD, found the maternal mortality rate was 26 times greater than the national average. This figure has not improved since the last time this population was assessed.

Newswise: The Medical Minute: Never had a lipid panel? Here’s why it’s important
Released: 1-Feb-2023 11:25 AM EST
The Medical Minute: Never had a lipid panel? Here’s why it’s important
Penn State Health

Know your numbers? A Penn State Health cardiologist says a lipid panel can help you stave off a heart attack.

Released: 31-Jan-2023 5:05 PM EST
The latest research news on surgery and transplants
Newswise

Below are some of the latest articles that have been added to the Surgery and the Transplantation channels on Newswise, a free source for journalists.

Released: 31-Jan-2023 1:15 PM EST
Artificial Blood Product One Step Closer to Reality With $46 Million in Federal Funding
University of Maryland School of Medicine

A University of Maryland School of Medicine (UMSOM) physician-scientist will head a new federally-funded research program to develop and test a whole blood product, storable at room temperature, that can be used to transfuse wounded soldiers in the field within 30 minutes of injury, potentially saving thousands of lives.

Newswise: Scientists Document Two Separate Reservoirs of Latent HIV in Patients
Released: 31-Jan-2023 12:05 PM EST
Scientists Document Two Separate Reservoirs of Latent HIV in Patients
University of North Carolina School of Medicine

UNC-Chapel Hill scientists and colleagues provide indirect evidence for the existence of a distinct latent reservoir of CD4+ T cells in the central nervous system, by analyzing rebound virus in the cerebral spinal fluid during the period when people had just stopped taking ART.

Released: 30-Jan-2023 3:55 PM EST
New mathematical model shows how the body regulates potassium
University of Waterloo

Having levels of potassium that are too high or too low can be fatal. A new mathematical model sheds light on the often mysterious ways the body regulates this important electrolyte.

   
Released: 30-Jan-2023 8:05 AM EST
NUS researchers revisit potent drug as promising treatment for acute leukaemia
National University of Singapore (NUS)

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has breathed new life into an existing drug — combatting a type of blood cancer called T-cell acute lymphoblastic leukaemia, or T-ALL. The drug, called PIK-75, was initially discovered over a decade ago but was dismissed in favour of newer ones. Now, it has made a comeback that deems it unmissable — the researchers established that the drug could block not just one but two crucial cancer-causing pathways of T-ALL, enabling them to develop new treatments that could effectively stem the disease.



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