Feature Channels: Personalized Medicine

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Released: 1-Feb-2019 12:00 PM EST
More than 60 Leading Health Care Organizations Call on CMS to Maintain Coverage for Medically Necessary Cancer Testing
Association for Molecular Pathology

Leading health care companies and organizations representing patients, providers, academic medical centers, laboratories, and diagnostic manufacturers urged the Centers for Medicare and Medicaid Services to revise its interpretation of the National Coverage Determination for Next Generation Sequencing.

Released: 30-Jan-2019 12:05 PM EST
GW Researchers Call for Big Data Infrastructure to Support Future of Personalized Medicine
George Washington University

Researchers from the George Washington University , the U.S. Food and Drug Administration, and industry leaders published in PLOS Biology, describing a standardized communication method for researchers performing high-throughput sequencing called BioCompute.

Released: 25-Jan-2019 4:05 PM EST
First US Patient in Novel Stem Cell Trial for Stroke Disability Enrolled at UTHealth
University of Texas Health Science Center at Houston

The first U.S. patient to participate in a global study of a stem cell therapy injected directly into the brain to treat stroke disability was enrolled in the clinical trial this week at The University of Texas Health Science Center at Houston (UTHealth).

Released: 23-Jan-2019 3:05 PM EST
Hope for life
UT Southwestern Medical Center

UT Southwestern Medical Center is helping the Duff family organize a gene therapy clinical trial to treat Talia’s condition, called Charcot Marie Tooth disease, type 4J (CMT4J).

Released: 23-Jan-2019 8:00 AM EST
Targeted treatment shrinks deadly pediatric brain tumors
Sanford Burnham Prebys

For children—whose tiny bodies are still growing—chemotherapy and radiation treatments can cause lifelong damage. Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have reported that a targeted therapy that blocks a protein called LSD1 was able to shrink tumors in mice with a form of pediatric brain cancer known as medulloblastoma. LSD1 inhibitors are currently under evaluation in clinical trials for other cancers. The study was published in Nature Communications.

Released: 21-Jan-2019 11:05 AM EST
Keeping astronauts healthy during deep space missions
Michigan State University

George Mias, Michigan State University biochemistry and molecular biology researcher, believes precision medicine -- a personalized approach using technology to analyze an individual's wellness to predict and possibly prevent illnesses -- can keep astronauts healthy during deep space missions.

   
Released: 17-Jan-2019 9:00 AM EST
Access to Care, Knowledge About Genetic Testing and Clinical Trials Identified as Key Issues in Landmark Survey of Neuromuscular Community
Muscular Dystrophy Association (MDA)

ONEVoice, a landmark survey funded by the Muscular Dystrophy Association (MDA) and conducted by Edge Research, has identified key areas of concern among more than 3,000 respondents – 2,430 adults with neuromuscular disease and 932 caregivers/family members – as well as ways in which many of these concerns can be addressed.

Released: 16-Jan-2019 8:00 AM EST
UNLV Startup Uses Genes to Create Personalized Diets
University of Nevada, Las Vegas (UNLV)

Food Genes and Me is a site and software that lets users figure out health risks and how to solve them within minutes.

   
Released: 15-Jan-2019 9:35 AM EST
Moffitt Cancer Center Hires New Vice Chair of the Department of Genitourinary Oncology
Moffitt Cancer Center

Manish Kohli, M.D., has joined Moffitt Cancer Center as the vice chair of the Department of Genitourinary Oncology. He also has an extensive research background, focusing on creating new ways to bring individualized care to patients.

Released: 7-Jan-2019 9:45 AM EST
Personalized vaccine to be tested for the first time in patients with kidney cancer
Dana-Farber Cancer Institute

By pairing a novel personalized cancer vaccine with a more established immunotherapy drug that is administered to patients in an innovative fashion, scientists at Dana-Farber Cancer Institute are testing a first-of-its-kind strategy aimed at improving outcomes for kidney cancer patients who are at high risk of recurrence following surgery.

Released: 19-Dec-2018 11:05 AM EST
Edging Closer to Personalized Medicine for Patients with Irregular Heartbeat
Washington University in St. Louis

Biomedical engineer Jon Silva led an international team that determined which patients would benefit the most from a commonly used drug treatment.

Released: 11-Dec-2018 10:00 AM EST
NUS SINAPSE Director Professor Dean Ho elected as Fellow of the prestigious National Academy of Inventors
National University of Singapore (NUS)

Professor Dean Ho, Director of the Singapore Institute for Neurotechnology at the National University of Singapore, has been elected as a Fellow of the United States National Academy of Inventors, the highest professional accolade for academic inventors.

   
Released: 10-Dec-2018 12:00 PM EST
Human Organoids to Speed Drug Development and Personalized Treatments;
American Society for Cell Biology (ASCB)

Bethesda, MD, December 4, 2018 – Human organoids are being hailed as a major development in biomedicine in a report issued by the American Society for Cell Biology (ASCB) to be released Monday, Dec. 10 at a session at the 2018 ASCB|EMBO Meeting in San Diego, CA.

Released: 6-Dec-2018 10:00 AM EST
PET Scans to Optimize Tuberculosis Meningitis Treatments and Personalize Care, Study Finds
Johns Hopkins Medicine

Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain—or tuberculosis meningitis (TBM)—is often deadly, always hard to treat, and a particular threat to young children.

13-Nov-2018 10:15 AM EST
How Does the Precision Medicine Initiative Affect Me?
Society for Risk Analysis (SRA)

Precision medicine will extend beyond prediction, diagnosis and treatment of disease to also include broader health initiatives, including prevention, nutrition and wellness. These new procedures raise novel legal, policy and ethical issues.

   
Released: 30-Nov-2018 10:05 AM EST
2018 Value Assessment Challenge Award Recipients to Outline Research Projects at Personalized Medicine Coalition Policy Meeting & Webinar on Dec. 12 in Washington, D.C.
PhRMA Foundation

The PhRMA Foundation and the Personalized Medicine Coalition (PMC) partnered earlier this year for the 2018 Value Assessment Challenge Awards — designed to encourage innovative approaches in defining and measuring value in health care.

5-Nov-2018 9:15 AM EST
Risk Score-Guided Care Reduces Mortality Rate in High-Risk Heart Failure Patients by Nearly 50 Percent
Intermountain Medical Center

New team-based care guided by a personalized risk score for heart failure patients reduced the mortality rate of high-risk heart failure patients by nearly 50 percent, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.

Released: 8-Nov-2018 10:00 AM EST
Harvard University Receives Transformational Gift for Harvard Medical School
Harvard Medical School

The $200-million commitment will fund: o Fundamental curiosity-driven research and a therapeutics initiative to catalyze the development of new treatments o Integrated data science and artificial intelligence capabilities and applications o Cross-disciplinary research across the Harvard life sciences ecosystem o LifeLab Longwood, an incubator for early-stage, high-potential biotech start-ups In honor of the gift—the largest in Harvard Medical School history—the School will name a research institute for the donor to recognize the pioneering work of its basic science and social science departments.

Released: 1-Nov-2018 9:20 AM EDT
Precision Medicine Leader Syapse to Utilize NCCN Biomarkers Compendium for Clinical Care
National Comprehensive Cancer Network® (NCCN®)

New agreement between National Comprehensive Cancer Network and Syapse will augment health information technology around precision medicine and biomarkers in cancer care

Released: 29-Oct-2018 4:45 PM EDT
Radiation therapy cuts low risk of recurrence by nearly three-fourths for patients with “good risk” breast cancer
American Society for Radiation Oncology (ASTRO)

A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report. These 12-year follow-up data from the only prospective, randomized trial to compare recurrence outcomes after treatment for low-risk ductal carcinoma in situ (DCIS) were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology (ASTRO).

Released: 22-Oct-2018 3:05 PM EDT
Pancreatic Cancer Genetic Marker May Predict Outcomes with Radiation Therapy
Thomas Jefferson University

Research scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The discovery may help physicians provide better treatment options for patients.

Released: 10-Oct-2018 4:35 PM EDT
PhRMA Foundation and Personalized Medicine Coalition Announce 2018 Value Assessment Challenge Award Recipients
PhRMA Foundation

The PhRMA Foundation and the Personalized Medicine Coalition (PMC) have announced the recipients of the 2018 Value Assessment Challenge Awards – designed to encourage innovative approaches in defining and measuring value in health care.

Released: 9-Oct-2018 2:05 PM EDT
由Mayo Clinic的专业知识所支持,新Mayo Clinic GeneGuide DNA检测应用程序能提供基因检测
Mayo Clinic

Mayo Clinic与个人基因组学公司Helix发布了一种名为“Mayo Clinic GeneGuide”的新DNA产品。 该基于DNA的产品能为健康个人提供基因测试以及相关的个人健康教育。该产品由Mayo医学知识和专业经验所支持。

Released: 1-Oct-2018 9:45 AM EDT
New Study Finds Nanoparticles Show Promise in Therapy for Triple-Negative Breast Cancer
George Washington University

A team led by Dr. Adam Friedman from the GW School of Medicine and Health Sciences found nanoparticle technology shows promise in therapy for triple-negative breast cancer.

28-Sep-2018 10:30 AM EDT
New Mayo Clinic GeneGuide DNA testing application provides genetic testing, insights backed by Mayo Clinic expertise
Mayo Clinic

Mayo Clinic released a new DNA product with Helix, a personal genomics company, called "Mayo Clinic GeneGuide." The DNA-powered product provides healthy individuals with genetic testing and insights with a focus on education. This product is backed by Mayo medical science and expertise.

21-Sep-2018 5:05 AM EDT
Harnessing Artificial Intelligence to Improve Drug Combination Design and Personalized Medicine
SLAS

A new auto-commentary looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can be used to improve drug development and personalized medicine.

Released: 24-Sep-2018 11:05 AM EDT
Magee-Womens Research Institute Hosts Summit Convening Global Leaders to Chart Path for Accelerated Medical Discoveries
Health Sciences at the University of Pittsburgh

The international summit will convene leaders in reproductive biology, precision medicine, public health and global health advocacy. The experts will share groundbreaking research and will culminate with crowdsourcing ideas on how to move women’s health to the forefront of medical research.

   
Released: 21-Sep-2018 5:05 PM EDT
Study seeks to improve cancer survival for Latinos, Asians and Blacks
UC Davis Health

UC Davis Comprehensive Cancer Center has received a $6.3 million grant from the National Cancer Institute’s (NCI) Center to Reduce Cancer Health Disparities for a 5-year study to tease out why some ethnic and racial minority groups fare worse than whites when they get cancer and to find more precise treatments to improve their chances of survival.

17-Sep-2018 6:00 AM EDT
Scientists Grow Human Esophagus in Lab
Cincinnati Children's Hospital Medical Center

Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The newly published research in the journal Cell Stem Cell is the first time scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body.

Released: 18-Sep-2018 8:20 AM EDT
Using Next-Generation Sequencing to Target Healthcare Interventions
ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced the publication of a series of articles that tackle the challenges associated with assessing the value of next-generation sequencing technologies in clinical care.

Released: 17-Sep-2018 4:40 PM EDT
The Cancer Center at BIDMC Opens a Personalized Immunotherapy Cancer Vaccine Facility
Beth Israel Lahey Health

The Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) today announced the opening of the Randi and Brian Schwartz Family Cancer Immunotherapy and Cell Manipulation Facility. The state-of-the-art laboratory expands BIDMC’s research capacity with the ultimate goal of accelerating the delivery of new immunotherapies to patients with cancer.

Released: 10-Sep-2018 9:40 AM EDT
U-M cancer researcher awarded $6.5M Outstanding Investigator Award to explore precision oncology
Michigan Medicine - University of Michigan

A new grant to University of Michigan Rogel Cancer Center member Arul Chinnaiyan, M.D., Ph.D., will provide long-term support to increase understanding of genetic markers to leverage targeted treatments for cancer.

Released: 31-Aug-2018 3:05 PM EDT
AANEM Recognizes Research on Precision Medicine in Neuromuscular and Musculoskeletal Medicine
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

For the 2018 annual meeting of the AANEM, more than 200 research abstracts were submitted on various topics related to neuromuscular and electrodiagnostic medicine. However, each year, special recognition is awarded to the authors of the best research abstracts (up to 10 abstracts) submitted on the AANEM President’s chosen topic.

Released: 31-Aug-2018 10:05 AM EDT
Genetics and Pollution Drive Severity of Asthma Symptoms
National Institute of Environmental Health Sciences (NIEHS)

Asthma patients, with a specific genetic profile, exhibit more intense symptoms following exposure to traffic pollution, according to researchers at the National Institutes of Health and collaborators. The study appeared online in Scientific Reports.

   
7-Aug-2018 8:05 AM EDT
Talented 12: Chemical & Engineering News announces its 2018 rising stars in chemistry
American Chemical Society (ACS)

Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society (ACS), is today unveiling its annual “Talented 12” list. This award program, now in its fourth year, and for the first time sponsored by Thermo Fisher Scientific, recognizes young global stars in the chemical sciences that are working to solve some of the world’s most challenging problems. These up-and-coming innovators in chemistry will be debuted at an event today at ACS’ 256th National Meeting & Exposition. They are also featured in this week’s issue of C&EN.

Released: 13-Aug-2018 3:45 PM EDT
University Hospitals Seidman Cancer Center Opens Car-T Therapy Study for Non-Hodgkin’s Lymphoma
University Hospitals Cleveland Medical Center

University Hospitals Seidman Cancer Center in Cleveland has a new clinical trail to study the safety of CAR-T therapy for Non-Hodgkin's lymphoma. In addition, UH is manufacturing on-site the cells used in the trial.

Released: 13-Aug-2018 2:05 PM EDT
Rethinking the Stroke Rule "Time is Brain"
Loyola Medicine

In 1993, neurologist Camilo Gomez, MD, coined a phrase that became a fundamental rule of stroke care: "Time is brain!" The longer therapy is delayed, the less chance it will succeed. But the "time is brain" rule is not as simple as it once seemed, Dr. Gomez now reports in the Journal of Stroke & Cerebrovascular Diseases.

6-Aug-2018 2:00 PM EDT
Lessons from Flies: Genetic Diversity Impacts Disease Severity
University of Utah Health

By analyzing thousands of flies, scientists at University of Utah Health found that variation in a background gene, called Baldspot, can make a difference in severity of the disease.

Released: 2-Aug-2018 9:00 AM EDT
A New Autoimmune Disease Is Found, Along with a Personalized Treatment for a Child's Rare Illness
Children's Hospital of Philadelphia

Elijah Patino is a happy, healthy seven-year-old now, but it took a while to get there. For much of his life, he had a mysterious disease that made it painful to eat and painful to play. A pediatric immunologist resolved this "diagnostic odyssey" by identifying the molecular cause of this autoimmune condition, then crafted a low-dose immunosuppressive regimen to provide a precise treatment.

Released: 1-Aug-2018 1:00 PM EDT
CRISPR diversifies: Cut, paste, on, off, and now– evolve!
Innovative Genomics Institute

Scientists at the Innovative Genomics Institute have concocted a transformative new way to harness the power of evolution. Today in Nature, researchers at UC Berkeley describe yet another creative application for CRISPR: a platform to spur evolution of specific genes inside cells. Their inventive new system, “EvolvR,” lets scientists shake up the DNA letters in their gene of choice until they find the variation that’s just right. The technology opens up countless possibilities, like engineering yeast that efficiently turn waste into biofuels, or developing new human therapeutics.

   
Released: 30-Jul-2018 9:05 AM EDT
Software Framework Designed to Accelerate Drug Discovery Wins IEEE International Scalable Computing Challenge
Brookhaven National Laboratory

Designing a new pharmaceutical drug takes years of research, and now chemists and computational and computer scientists have developed a software framework that could help expedite this process by supporting accurate and rapid calculations of how strongly drug compounds bind to target molecules.

   
Released: 24-Jul-2018 3:00 PM EDT
Fitness Trackers Prove Helpful in Monitoring Cancer Patients
Cedars-Sinai

Fitness trackers can be valuable tools for assessing the quality of life and daily functioning of cancer patients during treatment, a new study has found. The trackers, also known as wearable activity monitors, include commercial devices worn on the wrist that log a wearer's step counts, stairs climbed, calories, heart rate and sleep.

Released: 26-Jun-2018 7:50 AM EDT
UPMC/Pitt Launch Advanced Genome Sequencing Center
Health Sciences at the University of Pittsburgh

Center will help diagnose diseases, advance immunotherapy research and guide treatment choices.

Released: 14-Jun-2018 5:05 PM EDT
University Hospitals selects 2bPrecise to deliver genomic insights at point of care
University Hospitals Cleveland Medical Center

University Hospitals has selected the 2bPrecise platform to make genomic data points more accessible to physicians allowing for the data to be part of the medical record and subsequently shape and tailor the best treatment or therapy options for patients.

Released: 13-Jun-2018 1:05 PM EDT
Mayo Clinic discovery is first step toward new bacteria-based constipation treatment
Mayo Clinic

Genetically engineered bacteria are showing promise as a new treatment for constipation, researchers at the Mayo Clinic Center for Individualized Medicine have discovered in a mouse study. The finding is significant in part because there are few approved constipation remedies on the market. The research is published in Cell Host & Microbe.

Released: 11-Jun-2018 3:45 PM EDT
Researchers Identify Dozens of New Gene Changes That Point to Elevated Risk of Prostate Cancer in Men of European Descent
Case Western Reserve University

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent. The findings, published in a research letter in Nature Genetics, contain significant implications for which men may need to be regularly screened because of higher genetic risk of prostate cancer.

Released: 5-Jun-2018 8:05 PM EDT
UNLV Awarded $11.4 Million Federal Grant to Advance Personalized Medicine in Nevada
University of Nevada, Las Vegas (UNLV)

UNLV was recently awarded an $11.4 million grant from the National Institutes of Health (NIH) to build Nevada’s first center of excellence in personalized medicine. The five-year award marks the first time UNLV will lead a project funded through the NIH’s competitive Center of Biomedical Research Excellence (COBRE) program. It’s also believed to be the first COBRE program in the nation focused exclusively on personalized medicine.

Released: 31-May-2018 9:00 AM EDT
Philips and Dana-Farber operationalize and scale Clinical Pathways
Dana-Farber Cancer Institute

he Dana-Farber Clinical Pathways will be deployed through the Philips IntelliSpace Oncology Platform, providing clinical decision support to physicians via a patient-centric solution.



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