Despite seeing it millions of times in pretty much every picture book, every novel, every newspaper and every email message, people are essentially unaware of the more common version of the lowercase print letter “g.”
A new FAU study shows that expatriates’ personality characteristics have a lot to do with how well they adjust and whether they succeed and provide a return on a company’s considerable investment in an individual.
Scientists at The Scripps Research Institute have discovered a new aspect of the flu virus and how it interacts with antibodies in the lungs.
Material left out of common processes for sequencing genetic material in cancer tumors may actually carry important information about why only some people respond to immunotherapy, possibly offering better insight than the type of material that is being sequenced, according to a study by Mount Sinai researchers published on April 3 in Cell Reports.
Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma (also known as acoustic neuroma) cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus. The findings, published online today in Scientific Reports, suggest that mifepristone is a promising drug candidate to be repositioned for the treatment of these tumors.
A team of researchers including scientists from the University of Georgia has found that the resurgence of pertussis, more commonly known as whooping cough, in the U.S. is a predictable consequence of incomplete coverage with a highly effective vaccine. This finding goes against pervasive theories on why we are seeing a steady increase in the disease even though the vaccine is given at an early age.
Seven of the 11 animal viruses tested can potentially survive the transglobal journey from Asia or Europe to the United States in at least two commonly imported feed ingredients. That means feed biosecurity should be a major priority.
A new study suggests that resistance exercise may improve indicators of type 2 diabetes by increasing expression of a protein that regulates blood sugar (glucose) absorption in the body.
Typically, when a soundwave strikes a surface, it reflects back at the same fundamental frequency with a different amplitude. A new model, reported in the Journal of Applied Physics, shows that when a sound wave hits a nonlinear elastic metasurface, the incident fundamental frequency does not bounce back. Instead, the metasurface converts that energy into the wave’s second harmonic resonance. Developing this metasurface could help architects reduce noise from performance halls to cityscapes.
Cancer therapies that target a specific protein have improved outcomes for patients. However, many patients eventually develop resistance to these targeted therapies and their cancer comes back. It is believed that differences among tumor cells, or heterogeneity, may contribute to this drug resistance. Moffitt Cancer Center researchers are using a unique approach by combining typical cell culture studies with mathematical modeling to determine how heterogeneity within a tumor and the surrounding tumor environment affect responses to targeted drug therapies.
Alcohol use in social settings can have both desirable and undesirable effects – ranging from better mood and less anxiety to verbal and physical aggression, including violence. These outcomes often reflect the interplay of factors that are both internal and external to an individual. Intra-individual differences in alcohol reactions contribute to the various internal responses to drinking that a person may have; for example, alcohol can induce both positive and negative effects in the same person at different times. However, how that person acts upon impulses that he or she may have can depend on inter-individual differences, such as the individual’s frequency or intensity of drinking in comparison to others. This study examined the influence of inter-individual differences in alcohol use on intra-individual perceptions of drinking during real-world social interactions.
So what is it about the link between drinking coffee and living longer? Could it be the 200 plus organic compounds in the coffee bean itself and its proven benefits of reducing inflammation and regulating glucose levels? Or could it be something else?
Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of new research suggesting that while payers recognize the value of real-world evidence, the use of such studies to inform pharmacy and therapeutic (P&T) committee decisions is limited.
Few older adults use medical marijuana, a new national poll finds, but the majority support its use if a doctor recommends it, and might talk to their own doctor about it if they developed a serious health condition. And two-thirds say the government should do more to study the drug’s health effects.
Differences between signed and spoken languages are significant, yet the underlying neural processes we use to create complex expressions are quite similar for both, a team of researchers has found.
Rear-facing car seats have been shown to significantly reduce infant and toddler fatalities and injuries in frontal and side-impact crashes, but they’re rarely discussed in terms of rear-impact collisions. Since rear-impact crashes account for more than 25 percent of all accidents, researchers at The Ohio State University Wexner Medical Center conducted a new study to explore the effectiveness of rear-facing car seats in this scenario.
By Kerry Bennett Office of the Vice President for ResearchA new study published in Nature Physics describes how a team of scientists used a laser beam to gain access to long-lived sound waves in crystalline solids as the basis for a potentially new approach to information processing and storage. One of Northern Arizona University’s newest physicists, assistant professor Ryan Behunin, is a co-author of the study.
A group of Penn researchers hopes to improve the understanding of these present-day ailments by looking at the very engine of evolution: natural selection in humans.
The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers.
Hospital payment experiment in Maryland failed to deliver on the promise of shifting care from hospitals toward less expensive outpatient and primary care settings. Researchers say that weak incentives for physicians may have limited the program’s effectiveness.
A new study from the Johns Hopkins Bloomberg School of Public Health found that the uninsured face significant barriers to primary care, highlighting a group that remains vulnerable even after the Affordable Care Act insurance expansions. With trained auditors depicting low-income new uninsured patients, the study found that fewer than one in seven could confirm an office visit occurred if they were required to make payment arrangements to cover the cost of the visit.
Earth has had moderate temperatures throughout its early history, and neutral seawater acidity. This means other rocky planets could likely also maintain this equilibrium and allow life to evolve.
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.
Rising drug prices have gotten a lot of attention lately, but the actual cost of prescription medications is more than just the bill. Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego estimate that illness and death resulting from non-optimized medication therapy costs $528.4 billion annually, equivalent to 16 percent of total U.S. health care expenditures in 2016. The analysis is published March 26 by Annals of Pharmacotherapy.
A range of less than one degree Fahrenheit (or half a degree Celsius) of climate warming over the next century could make all the difference when it comes to the probability of future ice-free summers in the Arctic.
Patients treated for heart attack were 48 percent less likely to have a sudden return to the hospital when educated using a multi-factored discharge and follow-up program
Columbia Engineering researchers have found that vegetation plays a dominant role in Earth’s water cycle, that plants will regulate and dominate the increasing stress placed on continental water resources in the future. “This could be a real game-changer for understanding changes in continental water stress going into the future,” says Prof. Pierre Gentine. In this paper, he demonstrates vegetation’s key role in responding to rising CO2 levels and shows how plants will regulate future dryness.
In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory. But because most of the proteins found in those synapses die and renew themselves so rapidly, scientists have had a hard time pinning down how synapses are stable enough to explain the kind of learning and memory that lasts a lifetime.
Prescription drug consumers confounded by the cost of their medications can get a peek behind the curtain thanks to new Washington University in St. Louis research into the complex “co-opetition” — cooperation and competition — among drug makers in the middleman-controlled US drug supply chain.But, as explained by Panos Kouvelis, the Emerson Distinguished Professor of Operations and Manufacturing Management at Olin Business School and director of The Boeing Center for Supply Chain Innovation, the system is so complex and opaque, it may be headed for government regulation.
Story tips: ORNL-led team cultivated a novel oral microbe in adults with periodontitis; ORNL partnered with FCA US and Nemak to develop a new cast aluminum alloy for engine cylinder heads, which could lead to better fuel efficiency; ORNL studies cast doubt on 40-year-old theory describing how plastic polymers behave during processing.
Physicists have identified a new state of matter whose structural order operates by rules more aligned with quantum mechanics than standard thermodynamic theory.
The vast majority of genetic mutations associated with cancer occur in non-coding regions of the genome, yet it’s unclear how they may influence tumor development or growth. Researchers at University of California San Diego School of Medicine and Moores Cancer Center identified nearly 200 mutations in non-coding DNA that play a role in cancer. Each mutation could represent a new cancer drug target.
Babies who died during their sleep while being watched by someone other than parents often had been placed in unsafe sleep positions, such as on their stomachs, or in unsafe locations, such as a couch, a new study has found.
Más del 50 por ciento de los médicos en Estados Unidos dicen sentir agotamiento en su trabajo. Por ello, Mayo Clinic y otros centros médicos principales publicaron hoy una “carta estatutaria para el bienestar de los médicos.”
Physicians who receive negative reviews online do not receive similar responses in rigorous patient satisfaction surveys, according to new Mayo Clinic research in Mayo Clinic Proceedings. Yet, compared with colleagues without negative reviews, they score lower on factors that go beyond patient interactions and are beyond their immediate control.
More than halfway across the universe, researchers have spotted the farthest individual star ever seen.
Scientists have directly measured the increasing greenhouse effect of methane at the Earth’s surface for the first time. A research team from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) tracked a rise in the warming effect of methane – one of the most important greenhouse gases for the Earth’s atmosphere – over a 10-year period at a DOE field observation site in northern Oklahoma.
A team led by scientists at Van Andel Research Institute (VARI) and Cedars-Sinai have developed a straightforward, computational way to measure cellular age, a feat that may lead to better, simpler screening and monitoring methods for cancer and other diseases.
Exposing infants to antacids or antibiotics in their first six months of life could increase their risk of developing allergies in childhood.
A team of computational biologists has developed an algorithm that can ‘align’ multiple sequencing datasets with single-cell resolution. The new method has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.
Using the Hubble Space Telescope and a quirk of nature called gravitational lensing, an international team of astronomers has found the most distant individual star ever discovered, dubbed "Icarus." This discovery provides new insight into the formation and evolution of stars in the early universe, the makeup of galaxy clusters, and the nature of dark matter.
A new study from a University of Iowa-led research team finds that women who are considering pregnancy would benefit from greater fitness. Using 25 years of data on pre-pregnant women, the researchers report that higher levels of pre-pregnancy fitness are associated with a reduced risk of developing gestational diabetes.
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University’s Brody School of Medicine.
Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis. The study, published today in Oncogene, represents significant progress in the clinical translation of previous basic scientific discoveries.
American clinicians rated white patients as significantly more likely to improve and more likely to adhere to recommended treatments than black patients, and to be more personally responsible for their health than black patients.
Alzheimer’s, Parkinson’s and Huntington’s disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.
A groundbreaking study of nearly 4,000 trauma patients evacuated from the frontlines in Afghanistan over a six-year period offers insight that can inform decisions on team composition, staff training and skill mix on the battlefield and beyond. The study is one of several articles on en route care published in the April 2018 issue of Critical Care Nurse.
We’ll pay more for unhealthy foods when we crave them, new neuroscience research finds. The study also shows that we’re willing to pay disproportionately more for higher portion sizes of craved food items.
In the search for extraterrestrial life, scientists have turned over all sorts of rocks. Mars, for example, has geological features that suggest it once had — and still has — subsurface liquid water, an almost sure prerequisite for life. Scientists have also eyed Saturn’s moons Titan and Enceladus as well as Jupiter’s moons Europa, Ganymede and Callisto as possible havens for life in the oceans under their icy crusts. Now, however, scientists are dusting off an old idea that promises a new vista in the hunt for life beyond Earth: the clouds of Venus.
Urothelial cancers of the bladder and upper urinary tract are among the most common cancers encountered worldwide. Now an international team of cancer researchers have developed a highly sensitive and specific non-invasive test as a biomarker for early detection of urothelial cancers. Details of this method known as UroSEEK, are published in eLife.
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