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Medicine

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Cancer, chronic myeloid cancer, Dr. Tefferi, Imetelstat, Myelofibrosis, Telomerase

Telomerase Targeting Drug Demonstrates Benefit in Myelofibrosis Treatment

Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.

Medicine

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City of Hope, New England Journal of Medicine (NEJM)

Trial of Telomerase Inhibitors Points to Lasting Treatments for Myeloproliferative Disorders

A multinational team of physicians and scientists from City of Hope, the San Francisco Bay area and Europe recently reported success of a phase II clinical trial of a novel drug against essential thrombocythemia (ET), one of three myeloproliferative neoplasms (MPNs).

Medicine

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Optogenetics, Depression, Addiction, Reward, Aversion, Dynorphin, Nucleus Accumbens (Nac)

Reward, Aversion Behaviors Activated Through Same Brain Pathways

New research at Washington University School of Medicine in St. Louis may help explain why drug treatments for addiction and depression don’t work for some patients. The conditions are linked to reward and aversion responses in the brain. And the research suggests that some treatments simultaneously stimulate reward and aversion responses, resulting in a net zero effect.

Science

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Erosion, Water Quality, Phosphorus, Watershed, runoff pollution, Sediment

Fingerprinting Erosion

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Watershed health and water quality issues are a growing concern. Researchers examined the sediments traveling downstream toward Lake Winnipeg. In order to better understand where sediments are coming from, they used a technique called color fingerprinting to identify the specific origin of the erosion.

Medicine

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Diabetes, Dementia, Tangles, tau, Memory, American Academy Of Neurology, AAN, Journal Neurology

Diabetes and Brain Tangles May Be Linked Independently of Alzheimer’s Disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer’s disease, according to a new study published in the September 2, 2015, online version of Neurology®, the medical journal of the American Academy of Neurology.

Medicine

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Diversity, Radiology, Mammogram, Mammography, Patient-Centered Care

Improving Racial Diversity and Patient Experience in Radiology Highlight September JACR

The September 2015 issue of the Journal of the American College of Radiology (JACR®) highlights efforts to improve diversity in radiology, new ways of improving the radiology patient experience and digital breast tomosynthesis integration in every day practice.

Medicine

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Wayne State University, Liver, Liver Fibrosis, Liver Cancer, air pollution exposure, Air Pollution

Scientists Discover Mechanism for Air Pollution-Induced Liver Disease

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A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine’s Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct adverse health effect on the liver and causes liver fibrosis, an illness associated with metabolic disease and liver cancer.

Medicine

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“Prehab” Before You Rehab

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For people contemplating a hip or knee replacement, the prospect of a long post-surgical recovery can be a daunting one. The grueling rehabilitation sessions, the frustration of re-learning everyday movements, the weeks of waiting to return to “normal”— it’s almost enough to make patients reconsider surgery. Now there is evidence that appropriate pre-surgical physical therapy — or “prehabilitation” — can help patients recover faster.

Medicine

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Texas A&M Health Science Center, Alcoholism, Addiction

Alcoholism: A Step Toward a Treatment

Scientists have pinpointed a population of neurons in the brain that influences whether one drink leads to two, which could ultimately lead to a cure for alcoholism and other addictions. A study, published in the Journal of Neuroscience by researchers at the Texas A&M Health Science Center College of Medicine, finds that alcohol consumption alters the structure and function of neurons in the dorsomedial striatum, a part of the brain known to be important in goal-driven behaviors.

Medicine

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Researchers Identify a New Approach for Lowering Harmful Lipids

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis.







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