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Medicine

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Cancer, Cancer Research, Dr. Jann Sarkaria, Massachusetts Institute Of Technology, National Cancer Institute, news release, Physical Sciences-Oncology Centers

Mayo Clinic and Massachusetts Institute of Technology Receive Grant to Support Physical Sciences-Oncology Center

ROCHESTER, Minn. — Mayo Clinic and the Massachusetts Institute of Technology (MIT) have been awarded a five-year, $9.7 million grant from the National Cancer Institute (NCI) to support a Physical Sciences-Oncology Center (PS-OC). Researchers hope to learn more about the physical parameters that limit drug delivery into brain tumors and use this information to build models that will help physicians better predict how the body will distribute a particular drug to brain tumors and help them select the best drug to treat each patient based on their unique tumor.

Medicine

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Tuburculosis, Supplement, supplement risks , supplemental nutrition, Botancal, Treatment, Drug Treatment, Botanical Products, Botanical Research, Herbal, Herbal Medicine, Herbal Remedies, Medical Treatment, Tuberculosis, tuberculosis resistance, Tuberculosis treatment

Anti-Tuberculosis Drug Disrupted by Botanical Supplement, Can Lead to Development of Disease

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A new study from the University of Missouri in partnership with scientists in Africa has uncovered evidence that these supplements and their antioxidants may reduce the effectiveness of prescription medications. The researchers examined the effects of a widely used African botanical supplement, called Sutherlandia, and found that it may disrupt the effectiveness of a common anti-tuberculosis drug. This could lead to the development of active tuberculosis and perhaps drug resistant forms of the pathogen in some patients.

Medicine

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Center for Individualized Medicine, Medical Research, Molecular Testing, Dna Sequencing, Pharmacogenomics, Precision Medicine, whole exome sequencing

4 Tips for Patients Seeking Individualized Medicine

The promise of precision medicine is becoming a reality as more doctors bring individualized therapies to the bedside.

Medicine

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Neuroscience, precision neuroscience, Personalized Medicine, Virginia Tech Carilion Research Institute, Virginia-Nordic Precision Neuroscience, Sunnaas Rehabilitation Hospital, University of Oslo, Roanoke

International Scientists Join Forces to Put ‘Precision’ Focus on Neuroscience

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For three days this week, Roanoke, Virginia, is the capital of the precision neuroscience world. The top minds of precision neuroscience are coming together in a think-tank setting to explore the challenges and promise of bringing personalized medicine to brain health.

Medicine

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Center for Individualized Medicine, Dna Sequencing, Medical Research, whole exome sequencing, Molecular Testing

4 Ways Individualized Medicine Can Be Applied Immediately to Patient Care

Individualized medicine is no longer the lore of science fiction. It is offering new hope for patients with cancer, heart disease, depression and rare diseases for which there historically have been no diagnosis or treatment. And that’s just the beginning.

Medicine

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Center for Individualized Medicine, Dna Sequencing, Medical Research, Minnesota News Releases, Molecular Testing, news releases, Pharmacogenomics, Precision Medicine

Mayo Clinic Patient: ‘Individualized Medicine Saved My Life’

What Karen Daggett didn’t know almost killed her. The medicine she relied on to control an irregular heartbeat wasn’t working and hadn’t for years and she didn’t understand why pain medication never seemed to make her feel better. She also had a history of not tolerating some over-the-counter medications. Silently, these drugs were building up in her system, causing harmful side effects until DNA testing at Mayo Clinic Center for Individualized Medicine showed some medications were incompatible with her genetic makeup.

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Alzheimer's Disease, Georgetown University Medical Center, Howard Fillit, Nilotinib, repurposing cancer drugs, R. Scott Turner, Chronic Myeloid Leukemia, Cognitive Impairment, Neuroinflammation, misfiled proteins, atophagy, plaques and tangles, tau, beta-amyloid, Charbel Moussa, Georgetown Memory Disorders Program, anti-neurodegenerative drug, Georgetown U

New Clinical Trial Will Test Cancer Drug as Alzheimer’s Treatment

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The Alzheimer’s Drug Discovery Foundation (ADDF) announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna® for use as a cancer therapy) in patients with Alzheimer’s disease.

Medicine

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Hepatitis, Hepatitis B, Hepatitis B research, Hepatitis B Virus, hepatitis B virus (HBV), pharmacological research, Pharmacology, Pharmacologic, pharmacologic compound, pharmacology and therapeutics, Drug Research, Drug Research and Development

NIH Grants MU $3 Million to Develop New Hepatitis B Treatments

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Hepatitis B (HBV) is a viral infection that increases the likelihood of developing liver cancer or liver failure. According to the World Health Organization, an estimated 2 billion people currently are infected with HBV, which is more than 10 times the number of people who have human immunodeficiency virus (HIV). Currently, treatment for hepatitis B infections is limited to one class of drugs that targets the virus. Stefan Sarafianos, an investigator with the University of Missouri Bond Life Sciences Center (BLSC) recently was awarded $3 million from the National Institutes of Health to study the disease. Building on existing research, he and his team will work on the development of new drugs to treat HBV.

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Inside the Lab: Using Botox to Advance Science

Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.

Medicine

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drug deliver, Tumor, Cancer, magnetic bacteria

Swarms of Magnetic Bacteria Could Be Used to Deliver Drugs to Tumors

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Researchers have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs.







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