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Personalized Medicine

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Medicine

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Genetics, Genomics, Electronic Medical Records, Electronic Health Record, Heart Disease, Cardiovascular Disease, Chronic Disease, Diabetes, Cholesterol, High Blood Pressure

Mount Sinai Receives $3.4 Million Grant to Initiate Study of Personalized Medicine in the Clinical Setting

Mount Sinai School of Medicine has been awarded a $3.4 million grant over four years from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) to begin the largest study of its kind, in which a patient’s genomic risk for disease is revealed in a lab, and then entered into an electronic medical record for use in determining treatment in the clinical care setting.

Medicine

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Gene Therapy, Gene Therapies, Cystic Fibrosis, Huntington Disease, Amyotrophic Lateral Sclerosis, ALS, Lou Gehrig's Disease, Alzheimer's Disease

Molecular Delivery Truck Serves Gene Therapy Cocktail

Scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with “misfolded” proteins.

Medicine

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Genomics, exome sequencing, whole genome sequencing, Center for Applied Genomics, Clinical Diagnosis, idiopathic hemolytic anemia, Mendelian disease

As New Data Wave Begins, A Gene Study in One Disease Finds Mutations in an Unrelated Disease

Researchers seeking rare gene variants in ADHD found that one patient had causative mutations in an unrelated disorder. The finding has implications about how to best return such information to research subjects.

Medicine

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consumer genetics, Genomics, GnuBIO, Dna Sequencing, early access DNA sequencing system, Pharmacogenomics Centre at the Montreal Heart Institute , Montreal Heart Institute , personalized health, Personalized Medicine, consumer genetics conference

GnuBIO Announces Delivery of First Early Access Desktop DNA Sequencing System to the Montreal Heart Institute

The GnuBIO System will make DNA sequencing scalable, simpler and more accessible.

Science

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consumer genetics, Genomics, personalized health, Personalized Medicine, Dna Sequencing, RNA sequencing

3rd Annual Consumer Genetics Conference to Examine the Advancements and Challenges in Consumer Genetics, and Address the Future of the Field

The 3rd Annual Consumer Genetics Conference, a yearly forum designed to spark meaningful conversation on the current state of direct-to-consumer genetics and shape the future of the field, will convene June 7 through June 9 at the Hynes Convention Center in Boston, Massachusetts.

Medicine

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Matching Targeted Therapies to Tumor’s Specific Gene Mutations May be Key to Personalized Cancer Treatment

Customizing targeted therapies to each tumor’s molecular characteristics, instead of a one-size-fits-all approach by tumor type, may be more effective for some types of cancer, according to research conducted by The University of Texas MD Anderson Cancer Center.

Medicine

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American Society of Clinical Oncology, ASCO

ASCO Releases Studies from Upcoming Annual Meeting

The American Society of Clinical Oncology (ASCO) today highlighted seven studies in a press briefing from among more than 4,000 abstracts publicly posted online at www.asco.org in advance of ASCO’s 47th Annual Meeting. An additional 17 plenary, late-breaking and other major studies will be released in on-site press conferences at the Annual Meeting.

Medicine

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Mount Sinai School Of Medicine, Personalized Medicine, personalized medicine, genes, drug response, pharmacogenomics, pharmacogenetics, , Genomics, Human Genome, Diabetes, Liver Disease, Heart Disease, Kidney Disease

New Research Shows Dramatic Shift in Understanding of Personalized Medicine

Researchers at Mount Sinai School of Medicine have made a critical discovery that may lead scientists to abandon the use of broad conventional ethnic labels—African-American, Hispanic, and Caucasian—to estimate a patient’s genetic risk for disease. This first-of-its kind study conducted with diverse patients receiving care at a single urban academic medical center, marks an important step in the clinical application of personalized medicine. The data are published online in the peer-reviewed journal PLoS ONE.

Medicine

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Journal of the American Medical Association, cancer survival rates, Personalized Medicine

Future of Personalized Cancer Care Is Promising and Near

Cancer survival rates could improve soon with whole-genome sequencing, according to two studies published in the April 20, 2011, issue of the Journal of the American Medical Association that describe the first clinical applications of the high-tech process in patients with cancer.

Medicine

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Cancer, Genome, Leukemia, Acute Myeloid Leukemia, Acute Promyelocytic Leukemia, Dna Sequencing, Cancer Susceptibility, TP53

Decoding Cancer Patients’ Genomes Is Powerful Diagnostic Tool

Two new studies in the Journal of the American Medical Association highlight the power of sequencing cancer patients’ genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer susceptibility mutations that can be passed from parent to child.

Medicine

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Cancer, cancer metabolism, Kimmel Cancer Center At Jefferson, Antioxidant, Personalized Medicine

Researchers Unlock Key to Personalized Cancer Medicine Using Tumor Metabolism

Jefferson researchers used gene signatures and energy metabolism to predict clinical outcome, rather than gene mutations.

Medicine

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DNA of 50 Breast Cancer Patients Decoded

In one of the largest cancer genomics investigations reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. This comparison allowed researchers to find mutations that only occurred in the cancer cells.

Medicine

Channels:

Breast Cancer, Genome, DNA, Estrogen Receptor Positive, Tumor, Mutations, Personalized Medicine

DNA of 50 Breast Cancer Patients Decoded Reveals Complexity and Hints Toward Personalized Medicine

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In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine.







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