Feature Channels: Personalized Medicine

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Released: 10-May-2017 4:05 PM EDT
Stroke, MS Patients Walk Significantly Better with Neural Stimulation
Case Western Reserve University

A research volunteer with multiple sclerosis and another who had suffered stroke walked significantly better and faster with the aid of neural stimulation systems, potentially laying the foundation for implanted systems that restore some independence to people in these populations.

Released: 8-May-2017 10:05 AM EDT
A Slingshot to Shoot Drugs Onto the Site of an Infection
Universite de Montreal

Chemists from Italy and Canada specializing in nanotechnology create a molecular slingshot that could shoot drugs at precise locations in the human body once triggered by specific disease markers.

Released: 3-May-2017 10:05 AM EDT
UAMS Researcher Presents Findings on Synthetic ‘Marijuana’ at National Meeting
University of Arkansas for Medical Sciences

Some people who use so-called synthetic marijuana, known by names such as K2 and Spice, may be unable to metabolize the drug, leading them to experience its most harmful effects, a UAMS researcher said today at a national scientific meeting in Chicago.

Released: 1-May-2017 12:05 PM EDT
Adjusting Meds May Reduce Fall Risk in Older Adults
University of Michigan

Simply adjusting the dose of an older adult's psychiatric medication could reduce their risk of falling, a new University of Michigan study suggests.

Released: 27-Apr-2017 9:00 AM EDT
Antidepressant May Enhance Drug Delivery to the Brain
National Institute of Environmental Health Sciences (NIEHS)

New research from the National Institutes of Health found that pairing the antidepressant amitriptyline with drugs designed to treat central nervous system diseases, enhances drug delivery to the brain by inhibiting the blood-brain barrier in rats. The blood-brain barrier serves as a natural, protective boundary, preventing most drugs from entering the brain. The research, performed in rats, appeared online April 27 in the Journal of Cerebral Blood Flow and Metabolism.

   
Released: 19-Apr-2017 10:05 AM EDT
Malaria Drug Successfully Treats 26-Year-Old Brain Cancer Patient
University of Colorado Cancer Center

Small trial uses chloroquine to nix the process of "autophagy" that some cancer cells use to resist treatment, resensitzing glioblastoma to targeted therapy

Released: 13-Apr-2017 7:05 AM EDT
Thorough Genotyping and Repurposed Drugs Key to Treating Small-Cell Lung Cancer, says Cancer Expert
Sbarro Health Research Organization (SHRO)

Cancer expert Antonio Giordano, MD, PhD, Director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, describes the recent progress and future possibilities of treating SCLC.

Released: 12-Apr-2017 1:05 PM EDT
A Simple Sniff
Washington University in St. Louis

A team of engineers from Washington University in St. Louis has combined nanoparticles, aerosol science and locusts in new proof-of-concept research that could someday vastly improve drug delivery to the brain, making it as simple as a sniff.

   
Released: 12-Apr-2017 4:05 AM EDT
Families of Boys with Duchenne Muscular Dystrophy Band Together to Fund Research
Kennedy Krieger Institute

Ryan’s Quest, Michael’s Cause and Pietro’s Fight are non-profits founded by families of boys with Duchenne muscular dystrophy who believe that their global collaboration is paramount to see potential therapies through the drug pipeline.

Released: 11-Apr-2017 3:05 PM EDT
Focus on Alzheimer’s Disease Shifts to Prevention
University of Alabama at Birmingham

UAB physicians say prevention, not cure, may be the key to coping with the rising incidence of Alzheimer's disease. New imaging techniques, coupled with a better understanding of the disease, provide new hope.

6-Apr-2017 12:05 PM EDT
Research Uncovers Potential New Treatment to Treat and Stop Progression of Cystic Fibrosis
George Washington University

Researchers published in Nature Medicine from the George Washington University, the University of Perugia, and the University of Rome have discovered a potential new drug to treat and stop the progression of cystic fibrosis. Thymosin α1 is a novel therapeutic single molecule-based therapy that not only corrects genetic and tissue defects, but also significantly reduces inflammation seen in cystic fibrosis patients.

7-Apr-2017 9:30 AM EDT
Matching Pre-Treatment Tumor Size to Strength of Immune Response Allows Tailoring of Melanoma Drug Regimen
Perelman School of Medicine at the University of Pennsylvania

A new study published in Nature provides clues that could enhance physicians’ ability to pinpoint, in real-time, which patients are not responding to therapy – and intervene with additional drugs to boost the chances of shrinking tumors.

30-Mar-2017 12:05 PM EDT
Low-Dose Penicillin in Early Life Induces Long-Term Changes in Behaviour
McMaster University

The researchers report that low-dose penicillin taken late in pregnancy and in early life of mice offspring, changes behaviour and the balance of microbes in the gut. While these studies have been performed in mice, they point to popular increasing concerns about the long-term effects of antibiotics.

   
1-Apr-2017 1:05 PM EDT
New Natural Estrogen-Progesterone Capsule Reduces Postmenopausal Hot Flashes
Endocrine Society

A natural, or bioidentical, combined estradiol-progesterone capsule (TX-001HR) significantly decreases the frequency and severity of moderate to severe hot flashes in postmenopausal women, the Replenish study finds. Results of this phase 3, randomized, placebo-controlled, multicenter trial will be presented Monday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.

Released: 3-Apr-2017 11:00 AM EDT
Gallbladder Removal Is Common. But Is It Necessary?
Johns Hopkins Medicine

Johns Hopkins researchers say that the findings they published in the current edition of The American Journal of Gastroenterology could have important implications for the field of personalized medicine.

Released: 30-Mar-2017 1:05 PM EDT
UAB Creates Triple-Threat Cancer-Fighting Polymer Capsules for Guided Drug Delivery
University of Alabama at Birmingham

Chemists have designed triple-threat cancer-fighting polymer capsules for guided drug delivery. They combine three traits: good imaging contrast with low-power ultrasound, stable packaging of the cancer drug doxorubicin, and ability to trigger drug release with low- or higher-power ultrasound.

   
Released: 29-Mar-2017 2:05 PM EDT
Fred Hutch Scientists to Cover Advances in Immunotherapy, Proteomics at AACR
Fred Hutchinson Cancer Center

Scientists from the Fred Hutchinson Cancer Research Center in Seattle are scheduled to present and discuss the latest developments in immunotherapy and proteomics at the American Association for Cancer Research Annual Meeting, Research Propelling Cancer Prevention and Cures, on April 1-5. What follows is a selection of the more than 30 Hutch presentations at the AACR gathering

Released: 21-Mar-2017 5:05 PM EDT
New Colon Cancer Biomarkers May Guide Development of Personalized Treatment
Baylor Scott and White Health

Researchers at Baylor Scott & White Research Institute identified a new genetic biomarker for colon cancer that may lead to development of more targeted treatment of the disease

Released: 16-Mar-2017 2:05 PM EDT
Updated Data on SBRT Radiation for NSCLC Lung Cancer Confirm Benefits of ‘One and Done’ Approach
Roswell Park Comprehensive Cancer Center

Collaborative study with Cleveland Clinic & SUNY Upstate Medical University shows that single high-dose SBRT treatment is as effective as three doses in patients with non-small cell lung cancer

Released: 16-Mar-2017 2:05 PM EDT
Scripps Florida Scientists Develop New Drug Delivery Method for Cancer Therapy
Scripps Research Institute

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

Released: 16-Mar-2017 9:30 AM EDT
Dana-Farber Faculty to Present Abstracts at 2017 AACR Annual Meeting April 1-5, 2017
Dana-Farber Cancer Institute

A summary of a select abstracts by Dana-Farber researchers being presented at 2017 AACR Annual Meeting in April

Released: 15-Mar-2017 3:05 PM EDT
When Proteins Court Each Other, the Dance Moves Matter
University at Buffalo

Proteins shake their bodies and wave their limbs — essentially dancing — all with the goal of optimizing their interaction with other molecules, including other proteins. A new study shows that, in biological courtship, dance moves matter. The findings help to lay a foundation for the development of drugs targeting molecular vibrations. Such pharmaceuticals would block proteins from carrying out tasks that contribute to disease.

Released: 15-Mar-2017 12:15 PM EDT
Exact Replication of Cancer Studies May Speed Development of Improved Cancer Drugs
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010–2012. A perspective in AACC’s Clinical Chemistry journal discusses the project’s preliminary results and suggests changes the research community can make to prevent reproducibility issues from inhibiting cancer care.

Released: 15-Mar-2017 12:05 PM EDT
New Alternative to Colonoscopy Is as Easy as Swallowing a Pill
Loyola Medicine

The patient ingests a capsule containing two miniature cameras on either end. As the capsule travels through the digestive tract, it captures images and wirelessly transmits them to a recorder the patient wears on a belt.

Released: 14-Mar-2017 2:05 PM EDT
New Desktop Reference Guide Highlights Adverse Health Effects of Chemicals for Physicians and Their Patients
University of Missouri Health

More than 87,000 chemicals are available commercially in the U.S., including analogues of bisphenol A (BPA), an industrial chemical that is used in consumer products. Frederick vom Saal, a University of Missouri endocrinologist and researcher, has studied BPA and other chemicals and their effects on humans and animals for more than 20 years. Now, vom Saal has released Integrative Environmental Medicine, a comprehensive book outlining practical resources and tools, such as websites and smartphone apps, to help health care practitioners promote healthier choices for themselves and their patients.

Released: 9-Mar-2017 9:00 AM EST
Personalized Medicine, Proton Therapy and More Advances in Lung Cancer Research to Be Featured at Symposium Next Week
American Society for Radiation Oncology (ASTRO)

The press program for next week’s 2017 Multidisciplinary Thoracic Cancers Symposium features research advances in lung cancer including immunotherapy, proton therapy and liquid biopsy, among others.

Released: 9-Mar-2017 8:00 AM EST
Bar-Ilan University Scientists Effectively Disrupt Communication Between Parasites That Spread Disease
Bar-Ilan University

A new intervention developed by Bar-Ilan University scientists to tamper with parasites' communication system may lead to the development of drugs to treat, and prevent the spread of, devastating diseases such as African sleeping sickness, leishmaniasis and Chagas' disease.

Released: 8-Mar-2017 11:05 AM EST
Mayo Clinic Researchers Identify Therapy That Shrinks Tumors in Patients with Multiple Myeloma
Mayo Clinic

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

Released: 7-Mar-2017 10:00 AM EST
New Drug Combination Targets Aggressive Blood Cancer
Van Andel Institute

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

Released: 7-Mar-2017 9:05 AM EST
Computer Models Could Allow Researchers to Better Understand, Predict Adverse Drug Reactions
North Carolina State University

Computer model shows what happens at the molecular level during severe allergic reactions to abacavir, a common HIV drug

23-Feb-2017 3:05 PM EST
Study: Wireless Stimulation May Ease Migraine Pain as Well as Drugs
American Academy of Neurology (AAN)

A preliminary study suggests that a new, wireless patch that you wear on your arm may help reduce migraine pain as well as drugs. The study is published in the March 1, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 1-Mar-2017 8:05 AM EST
New TB Drug Candidates Developed From Soil Bacteria
University of Warwick

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil - according an international collaboration of researchers, including the University of Warwick.

   
Released: 27-Feb-2017 3:05 PM EST
Collaborative Diabetes Clinic Lowers Health Care Costs
UC San Diego Health

Researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego are running a Diabetes Intensive Medical Management (DIMM) “tune up” clinic for complex type 2 diabetes patients. In a study published in the March 2017 issue of the Journal of Managed Care & Specialty Pharmacy, the researchers report the clinic’s economic benefits, which include an estimated cost avoidance of $5,287 per DIMM clinic patient over three years.

Released: 27-Feb-2017 9:00 AM EST
Cedars-Sinai to Study Most Effective Ways for Doctors to Discuss Opioid Use with Patients Suffering From Chronic Pain
Cedars-Sinai

Cedars-Sinai investigators are gearing up to study the most effective ways for doctors to discuss opioid use with chronic pain patients in an effort to reduce the impact of pain while curbing overuse of these addictive drugs. The research team has received $2 million from the Patient-Centered Outcomes Research Institute to conduct the study, which will launch in 2017.

Released: 23-Feb-2017 4:05 PM EST
Novel Amyloid Structure Could Lead to New Types of Antibiotics
American Technion Society

Researchers have discovered unique amyloid fibers used by the highly drug resistant Staphylococcus aureus bacterium (which causes MRSA). The findings could lead to new types of antibiotics with a novel mechanism of action for attacking bacterial toxins.

Released: 23-Feb-2017 10:05 AM EST
Science Exchange Online Marketplace Now Offers Eurofins Services for Drug Development
Science Exchange

/PRNewswire/ -- Science Exchange and Eurofins are excited to announce that Eurofins Central Laboratory is now a service provider listed on the Science Exchange marketplace for outsourced research services. This means that pharmaceutical and biotech companies around the world now have faster access to Eurofins's Clinical Testing portfolio, as well as its end-to-end analytical testing solutions from Drug Discovery to Product Testing.

   
Released: 22-Feb-2017 10:05 AM EST
White House Strategist to Lead UAB’s Personalized Medicine Institute
University of Alabama at Birmingham

Matthew Might, Ph.D., a renowned computer scientist and strategic leader appointed to the White House Precision Medicine Initiative by former President Barack Obama, has been named the inaugural director of the Hugh Kaul Personalized Medicine Institute at UAB.

Released: 21-Feb-2017 12:05 PM EST
Drugs That Alter Inhibitory Targets Offer Therapeutic Strategies for Autism, Schizophrenia
SUNY Downstate Health Sciences University

Researchers at SUNY Downstate recently discovered that an inhibitory brain receptor triggers synaptic pruning in adolescence. Drugs that selectively target these receptors, when administered during adolescence, can alter synapse number, with possible implications for the treatment of autism and schizophrenia.

Released: 17-Feb-2017 3:05 PM EST
Micro-RNA May Amplify Effectiveness of Sorafenib in Difficult Liver Cancer Cases
Sbarro Health Research Organization (SHRO)

Only 25% of patients respond to sorafenib treatment, so researchers have endeavored to understand its mechanism of action and discover a way to boost its effectiveness.

Released: 17-Feb-2017 3:05 PM EST
Placenta Provides Time Capsule for Autism Studies
UC Davis MIND Institute

In two recent studies, researchers at UC Davis have shown that placental tissue can provide critical information about the epigenetic landscape that influences fetal development.

Released: 14-Feb-2017 10:05 AM EST
Cancer Survivor and Noted Physician-Scientist Sandra Horning to Receive Roth Award
UC San Diego Health

Sandra Horning, MD, Chief Medical Officer and executive vice president of global development for Roche and Genentech, a member of the Roche Group, has been named the 2017 recipient of the Duane Roth Memorial Award, which will be presented February 16 at the annual Industry/Academia Translational Oncology Symposium at UC San Diego Moores Cancer Center.

Released: 10-Feb-2017 3:05 PM EST
Chiropractors Offer Alternative to NSAIDs for Back Pain
American Chiropractic Association

People suffering from back pain should consider first trying chiropractic services and other non-drug therapies in light of a new research review that found common over-the-counter and prescription pain medications have limited effectiveness for back pain and raise the risk of side-effects, according to the American Chiropractic Association (ACA).

Released: 10-Feb-2017 11:50 AM EST
Breaking Research Published in AACC’s Clinical Chemistry Journal Could Help to Combat Rise in Drivers Impaired by Edible Marijuana Consumption
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

Though marijuana edibles are becoming increasingly common, scant information exists on how to test drivers for impairment following their consumption. For the first time, research published today in AACC’s Clinical Chemistry journal evaluates the performance of roadside saliva tests for tetrahydrocannabinol (THC) following consumption of edibles, showing that lower THC cutoff points are needed for these tests to effectively detect marijuana ingestion.

Released: 9-Feb-2017 3:05 PM EST
Constant Challenge for Discovery Propels Harvinder Gill
Texas Tech University

The Texas Tech researcher has shown how vaccines can be administered more effectively through the use of creative methods of drug delivery.

Released: 9-Feb-2017 1:05 PM EST
Scientists Identify Aggressive Pancreatic Cancer Cells and Their Vulnerability
University of Texas MD Anderson Cancer Center

A team from The University of Texas MD Anderson Cancer Center describes this week in the journal Nature a series of preclinical experiments using patient-derived tumor xenografts (PDXs) and mouse models that point to potential treatments for patients with a rapidly-progressing and resistant subgroup of tumor cells.

Released: 8-Feb-2017 10:30 AM EST
Every Diagnosis of Cancer Should Come with One of These, Says Cancer Expert
Sbarro Health Research Organization (SHRO)

“Every cancer diagnosis should come with a referral to genetic counseling,” says cancer expert Dr. Antonio Giordano, President of the Sbarro Health Research Organization at Temple University.

Released: 7-Feb-2017 10:05 AM EST
UNM Cancer Center Researcher Discovers New Class of Drugs to Combat Aging Diseases
University of New Mexico Comprehensive Cancer Center

Eric Prossnitz, PhD and his team uncovered new details of the aging process. They discovered an altered balance between certain signaling molecules in the smooth muscle cells of blood vessels and the heart. The team also discovered a new class of drugs that combats an important part of the aging process.

3-Feb-2017 1:15 PM EST
A New Immunologic and Endocrine Syndrome
Universite de Montreal

After 10 years of research, a team at Université de Montréal's research centre has succeeded in deleting the Armc5 gene in experimental mice, discovering that its loss gives rise to a heretofore unidentified syndrome.

Released: 2-Feb-2017 4:05 PM EST
Drug Discovery Researchers Awarded Grant to Refine Malaria Drug
Virginia Tech

A research team from the Virginia Tech Center for Drug Discovery has received a $431,126 two-year grant from the National Institutes of Health to make improved versions of a promising compound called MMV008138, or 8138 for short.



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