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Medicine

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Schizophrenia, Schizophrenia Development, Genetics, Genetics and Schizophrenia, Genes and Schizophrenia

International Team Sheds New Light on Biology Underlying Schizophrenia

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As part of a multinational, collaborative effort, researchers from the University of North Carolina School of Medicine and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in what is the largest genomic study published on any psychiatric disorder to date.

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Mount Sinai

Common Gene Variants Account for Most of the Genetic Risk for Autism

Heritability trumps spontaneous glitches, environment

Science

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International Wheat Genome Sequencing Consortium, shotgun sequencing, wheat bread, wheat flour, wheat cereal, chromosome 3B, wheat genome, wheat genome sequencing

Scientists Complete Chromosome-Based Draft of the Wheat Genome

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Scientists have completed a chromosome-based draft sequence of the bread wheat genome as well as the first reference sequence of chromosome 3B, the largest chromosome in wheat.

Science

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Lung Cancer, Cancer, Tumors, Metastasis, genes, Genetics, focal adhesion kinase, Therapy, LKB1, Lkb1 Gene Mutation

New Gene Discovered That Stops the Spread of Deadly Cancer

Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world’s deadliest cancers. By identifying the cause of this metastasis—which often happens quickly in lung cancer and results in a bleak survival rate—Salk scientists are able to explain why some tumors are more prone to spreading than others. The newly discovered pathway, detailed today in Molecular Cell, may also help researchers understand and treat the spread of melanoma and cervical cancers.

Science

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Aging, Zebrafish, Senescence, developmental senescence, Genetics

Scripps Florida Scientists Identify Gene That Plays a Surprising Role in Combating Aging

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Scientists from The Scripps Research Institute have found in animal models that a single gene plays a surprising role in aging, a discovery that could lead to the possibility of using therapeutics, even commonly used ones, to manipulate the aging process itself.

Science

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Evolution Biology, Worms, RNA, Genetics, Hereditary, Traits

Study Shows How Effects of Starvation Can Be Passed to Future Generations

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A new study, involving roundworms, shows that starvation induces specific changes in so-called small RNAs and that these changes are inherited through at least three consecutive generations, apparently without any DNA involvement.

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biological pacemakers

Transplanting Gene into Injured Hearts Creates Biological Pacemakers

Cardiologists at the Cedars-Sinai Heart Institute have developed a minimally invasive gene transplant procedure that changes unspecialized heart cells into “biological pacemaker” cells that keep the heart steadily beating. The laboratory animal research, published online and in today’s print edition of the peer-reviewed journal Science Translational Medicine, is the result of a dozen years of research with the goal of developing biological treatments for patients with heart rhythm disorders who currently are treated with surgically implanted pacemakers.

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New Research Uncovers Genetic Identifier, Common Physical Traits for Autism; May Allow Clinicians to Determine Risk for Babies Still In Utero

A researcher at Seattle Children’s Hospital and Research Institute has found a genetic identifier for autism that includes physical features that may eventually allow clinicians to identify babies who are at risk for autism before they are born. This is the first time a genetic mutation has been linked to autism.

Medicine

Science

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Friendship, Natural Selection, Genetics, Social Networks, Kinship, Evolution, Friends and Genes

Genome-Wide Analysis Reveals Genetic Similarities Among Friends

If you consider your friends family, you may be on to something. A study from the University of California, San Diego, and Yale University finds that friends who are not biologically related still resemble each other genetically.

Science

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Ithaca College, Research, Anxiety, Mental Illness, Ian Woods, Biochemistry, Zebrafish, Tropical Fish, Genetics, Gene alterations, fish, Neuropeptides, Anxiety medications

Beneath the Surface: What Zebrafish Can Tell Us About Anxiety

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Ithaca College professor Iann Woods researches how genetics influence responses to stimuli that can trigger anxiety, and he’s using zebrafish — a tropical member of the minnow family named for the black stripes on their bodies — to do so. He and his team of student researchers examine how fish with tweaked genes respond to different triggers compared to unmodified fish. The work could someday lead to better, more nuanced medications for anxiety disorders.







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