Feature Channels: Blood

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Newswise: Correcting Blood Flow With an Implantable Clip
Released: 23-Feb-2022 12:00 PM EST
Correcting Blood Flow With an Implantable Clip
Valley Health System

A collaborative effort between The Valley Heart and Vascular Institute’s cardiology and structural heart teams, at The Valley Hospital, in Ridgewood, NJ, uncovers an underlying condition and mitigates James Freehill's symptoms.

Newswise: Blood test for Alzheimer’s highly accurate in large, international study
Released: 22-Feb-2022 3:00 PM EST
Blood test for Alzheimer’s highly accurate in large, international study
Washington University in St. Louis

A blood test developed at Washington University School of Medicine in St. Louis has proven highly accurate in detecting early signs of Alzheimer’s disease in a study involving nearly 500 patients from across three continents, providing further evidence that the test should be considered for routine screening and diagnosis. The study is available in the journal Neurology.

Released: 22-Feb-2022 2:20 PM EST
Gene Therapy for Thalassemia Ends Need for Transfusions in Young Children
Ann and Robert H. Lurie Children's Hospital of Chicago

Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age. Twenty-two patients were evaluated (ranging in age 4-34 years), including pediatric patients enrolled at Ann & Robert H. Lurie Children’s Hospital of Chicago.

17-Feb-2022 3:35 PM EST
The Latest Research News in Cardiovascular Health
Newswise

The Latest Research News in Cardiovascular Health

Released: 17-Feb-2022 1:05 PM EST
A possible cure for sickle cell?
Boston University School of Medicine

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

Newswise: Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Released: 17-Feb-2022 12:00 PM EST
Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Texas Tech University Health Sciences Center El Paso

Texas Tech University Health Sciences Center El Paso has received more than a quarter-million dollars to study the proteins that contribute to disease progression and drug resistance in acute myeloid leukemia.

Newswise: Rogue antibodies make cells “sticky” to trigger blood clots in COVID-19 patients
Released: 17-Feb-2022 11:15 AM EST
Rogue antibodies make cells “sticky” to trigger blood clots in COVID-19 patients
Michigan Medicine - University of Michigan

Scientists have discovered that “rogue” antibodies found circulating in the blood of COVID-19 patients have the potential to cause endothelial cells to lose their resistance to clotting. These antiphospholipid autoantibodies can trigger blood clots in the arteries and veins of patients with autoimmune disorders, including lupus and antiphospholipid syndrome. The findings provide an even stronger connection between autoantibody formation and clotting in COVID-19.

Newswise: Research reveals high-risk subtype of relapsed pediatric AML
16-Feb-2022 10:00 AM EST
Research reveals high-risk subtype of relapsed pediatric AML
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients.

Newswise: Music Therapy Improves Ability to Cope with Pain for Patients with Sickle Cell Disease
Released: 16-Feb-2022 11:40 AM EST
Music Therapy Improves Ability to Cope with Pain for Patients with Sickle Cell Disease
University Hospitals Cleveland Medical Center

A new study from University Hospitals Connor Whole Health found patients with Sickle Cell Disease who participated in music therapy learned new self-management skills and improved their ability to cope with pain.

Released: 15-Feb-2022 5:40 PM EST
UCLA Health at CROI: Presenting the case of a woman with HIV-1 in remission following specialized stem cell transplantation for leukemia
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers presented today the first case of a U.S. woman living with HIV-1 that is in remission after she received a new combination of specialized stem cell transplants for treatment of acute myeloid leukemia (AML). The oral abstract was presented at CROI 2022, the Conference on Retroviruses and Opportunistic Infections.

Released: 15-Feb-2022 5:05 PM EST
Stem cell infusion boosts sepsis survival in mice
eLife

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

Newswise: Smartphone app can vibrate a single drop of blood to determine how well it clots
8-Feb-2022 8:05 PM EST
Smartphone app can vibrate a single drop of blood to determine how well it clots
University of Washington

Researchers at the University of Washington have developed a new blood-clotting test that uses only a single drop of blood and a smartphone vibration motor and camera.

   
Released: 9-Feb-2022 2:00 PM EST
MD Anderson Research Highlights for February 9, 2022
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include a classification system to identify clinically actionable gene fusions, an improved method to culture tumor-infiltrating lymphocytes for non-small cell lung cancer and an effective combination therapy for patients with acute myeloid leukemia carrying specific mutations.

Released: 8-Feb-2022 7:00 AM EST
THC in Cannabis May Reduce Platelet Function
American Physiological Society (APS)

Using marijuana may lead to platelet dysfunction, according to a new study in nonhuman primates. Platelets, a component of blood, play a role in maintaining blood vessel (vascular) health and aid wound healing and placental development during pregnancy. The article is published ahead of print in the American Journal of Physiology-Cell Physiology.

Newswise: Metabolism of COVID-19 Antibodies from Convalescent Plasma Suggests Possible Safe Treatment for High Risk Children
Released: 7-Feb-2022 12:05 PM EST
Metabolism of COVID-19 Antibodies from Convalescent Plasma Suggests Possible Safe Treatment for High Risk Children
Johns Hopkins Medicine

Johns Hopkins Medicine researchers report that a prospective study of 14 infants and children demonstrated that convalescent plasma — a blood product collected from patients recovered from infections with the coronavirus (SARS-CoV-2) that causes COVID-19— was safe in high risk children infected with or exposed to the virus.

Newswise: Study of Penn Patients with Decade-Long Leukemia Remissions after CAR T Cell Therapy Reveals New Details About Persistence of Personalized “Living Drug” Cells
Released: 2-Feb-2022 12:50 PM EST
Study of Penn Patients with Decade-Long Leukemia Remissions after CAR T Cell Therapy Reveals New Details About Persistence of Personalized “Living Drug” Cells
Perelman School of Medicine at the University of Pennsylvania

Today, an analysis of these two patients published in Nature from the Penn researchers and colleagues from Children’s Hospital of Philadelphia explains the longest persistence of CAR T cell therapy recorded to date against CLL, and shows that the CAR T cells remained detectable at least a decade after infusion, with sustained remission in both patients.

Released: 2-Feb-2022 10:05 AM EST
Blood Test Could Help Predict a Deadly Pregnancy Complication
Michigan State University

A blood test could help doctors predict which pregnant women are likely to develop a life-threatening condition called pre-eclampsia, a study co-authored by a Michigan State University researcher found.

Released: 28-Jan-2022 10:35 AM EST
Study: Nearly 1 in 7 COVID patients in ICU experienced severe bleeding when given full-dose blood thinners
University at Buffalo

Patients with COVID-19 in the intensive care unit (ICU) prescribed full-dose blood thinners are significantly more likely to experience heavy bleeding than patients prescribed a smaller yet equally effective dose, according to a recent University at Buffalo-led study.

Released: 27-Jan-2022 4:10 PM EST
Pulse oximeter measurements of blood oxygen levels are unreliable in assessing severity of Covid-19 pneumonia across different ethnic groups
University of Nottingham

The severity of Covid-19 pneumonia can be difficult to assess in people from different ethnic groups, due to inaccurate readings from a device that measures the level of oxygen in the blood of patients.

Newswise: GW Researchers Create Test to Quickly Identify COVID-19 Infection and Disease Severity
Released: 27-Jan-2022 11:15 AM EST
GW Researchers Create Test to Quickly Identify COVID-19 Infection and Disease Severity
George Washington University

George Washington University researchers have developed a blood test that quickly detects if someone has COVID-19 and predicts how severely the immune system will react to the infection, according to a new study coming out today in PLOS One. The findings could one day lead to a powerful tool to help doctors determine the best treatment plan for people with COVID-19.

Released: 26-Jan-2022 8:05 AM EST
Researchers identify immunological markers for SARS-CoV-2 reinfection
American Society for Microbiology (ASM)

Many experts now predict that COVID-19, which so far has killed more than 5.5 million people worldwide, will remain endemic as new, infectious variants of SARS-CoV-2 emerge.

24-Jan-2022 3:00 AM EST
New Study Validates Benefits of Convalescent Plasma for Some COVID-19 Patients
NYU Langone Health

Transfusions of blood plasma donated by people who have already recovered from infection with the pandemic virus may help other patients hospitalized with COVID-19, a new international study shows.

Newswise: Simulation Models Exercise, Age Effects on Plaque Formation in Arteries
19-Jan-2022 1:20 PM EST
Simulation Models Exercise, Age Effects on Plaque Formation in Arteries
American Institute of Physics (AIP)

In Physics of Fluids, engineers from China use fluid dynamics simulations to study the effect of exercise at various ages on plaque formation in the arteries. The authors considered two arterial geometries, one with a bulging outer artery and the other without, and modeled the effect of exercise and age on blood flow. To model exercise, the authors digitized blood flow measurements from individuals in three age groups and used these flowrates as input to their computational model.

   
Released: 24-Jan-2022 3:40 PM EST
The Latest Research News from the Health Disparities Channel
Newswise

The latest research news from the Health Disparities Channel.

Released: 20-Jan-2022 5:50 PM EST
TV watching linked with potentially fatal blood clots
European Society of Cardiology

Take breaks when binge-watching TV to avoid blood clots, say scientists. The warning comes as a study reports that watching TV for four hours a day or more is associated with a 35% higher risk of blood clots compared with less than 2.5 hours. The research is published today in the European Journal of Preventive Cardiology, a journal of the ESC.1

Released: 20-Jan-2022 5:30 PM EST
‘Superpower’ nano bubbles could treat, prevent current and future strains of SARS-CoV-2
Northwestern University

Scientists at Northwestern Medicine and The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

Newswise: American College of Surgeons STOP THE BLEED® program signs with North American Rescue to offer STOP THE BLEED® items
Released: 20-Jan-2022 10:05 AM EST
American College of Surgeons STOP THE BLEED® program signs with North American Rescue to offer STOP THE BLEED® items
American College of Surgeons (ACS)

The American College of Surgeons (ACS) STOP THE BLEED® program recently announced it has signed with a new vendor, North American Rescue®, LLC (NAR), to offer STOP THE BLEED® Kits, equipment, and other bleeding control materials to the public through its online shop.

Newswise: Nano-sized vesicles with ACE2 receptor could prevent, treat infection from current and future strains of SARS-CoV-2
19-Jan-2022 3:15 PM EST
Nano-sized vesicles with ACE2 receptor could prevent, treat infection from current and future strains of SARS-CoV-2
University of Texas MD Anderson Cancer Center

Researchers from MD Anderson and Northwestern University have identified natural extracellular vesicles containing the ACE2 protein in the blood of COVID-19 patients that act as decoys to block infection from SARS-CoV-2

Newswise:Video Embedded automating-blood-smears-for-easier-malaria-diagnosis
VIDEO
12-Jan-2022 1:15 PM EST
Automating Blood Smears for Easier Malaria Diagnosis
American Institute of Physics (AIP)

In Review of Scientific Instruments, researchers have developed devices to automate blood smears. Their devices, called autohaem smear and smear+, can consistently create high-quality smears equivalent to those created by human experts, automating the smearing process so every smear is correct and consistent. A key goal of the project was to make the devices accessible to as many people as possible, so the researchers designed their devices to be easy to build, using readily available or 3D-printed components.

   
17-Jan-2022 3:05 PM EST
Direct oral anticoagulants significantly decrease recurrent venous thrombosis for adult cancer patients, Mayo Clinic study finds
Mayo Clinic

Direct oral anticoagulants should be considered the standard of care to treat adult patients with cancer-associated thrombosis, according to a new, ongoing study by Mayo Clinic researchers.

Newswise: Blood & Marrow Transplant Outcomes Exceed Expectations
Released: 17-Jan-2022 10:05 AM EST
Blood & Marrow Transplant Outcomes Exceed Expectations
Cedars-Sinai

The Cedars-Sinai Cancer Blood & Marrow Transplant Program’s one-year patient survival rate exceeded expectations compared to transplant centers in the U.S. whose similar patients underwent allogeneic transplants, according to a national report that tracks those outcomes.

Newswise:Video Embedded bare-shelves-in-the-blood-bank-means-threat-to-patient-care
VIDEO
Released: 14-Jan-2022 4:25 PM EST
Bare shelves in the blood bank means threat to patient care
Michigan Medicine - University of Michigan

A critical shortage of blood, which has stretched supplies thin nationwide, threatens hospitals' ability to provide many types of patient care. The Red Cross has just declared the first-ever national blood crisis. A blood bank director with nearly 40 years of experience urges every eligible person to step up and make an appointment to donate as soon as possible.

Newswise: The Medical Minute: Yes, the hospital needs your blood. And yes, it’s safe to give.
Released: 13-Jan-2022 7:05 AM EST
The Medical Minute: Yes, the hospital needs your blood. And yes, it’s safe to give.
Penn State Health

What does a blood shortage mean for patients? How did we get here? And why Type O? A Penn State Health blood bank director weighs in.

12-Jan-2022 11:05 AM EST
New blood cancer gene defect can be treated with existing drugs
Queen's University Belfast

A defective gene, normally found in blood cancers, could be treated with drugs already available for cancers with similar gene defects, scientists at Queen’s University Belfast and the University of Birmingham have revealed.

Newswise: New Research in JNCCN Raises Awareness of the Dangers of Septic Shock in Blood Cancer Patients
Released: 12-Jan-2022 8:35 AM EST
New Research in JNCCN Raises Awareness of the Dangers of Septic Shock in Blood Cancer Patients
National Comprehensive Cancer Network® (NCCN®)

New research in the January 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network examined the impact of septic shock on people with hematologic malignancies, finding 67.8% died in fewer than 28 days and only 19.4% remained alive after 90 days.

Newswise: Researchers at Children’s Hospital Los Angeles are unraveling the biological mechanism that triggers pain in people with sickle cell disease—and confirming what mothers have been saying all along
Released: 10-Jan-2022 10:05 AM EST
Researchers at Children’s Hospital Los Angeles are unraveling the biological mechanism that triggers pain in people with sickle cell disease—and confirming what mothers have been saying all along
Children's Hospital Los Angeles

Over the course of more than three decades studying sickle cell disease and caring for patients, Thomas Coates, MD, has learned an important lesson: listen to the mothers. It is their detailed accounts of their children’s pain that inspired his current research focus.

Released: 6-Jan-2022 12:05 PM EST
Emergency Response, Nervous Toxicity, Liver Injury Markers, and More Featured in January 2022 Toxicological Sciences
Society of Toxicology

The January 2022 issue of Toxicological Sciences launches the New Year with investigations in clinical and translational toxicology, as well as emerging technologies, methods, and models.

   
Released: 4-Jan-2022 10:05 AM EST
Aberrant Splicing of CD22 in Acute Lymphoblastic Leukemia Underlies Resistance to Immunotherapy
Children's Hospital of Philadelphia

Aberrant splicing of messenger RNAs encoding surface antigen CD22 leads to downregulation of this protein in pediatric B-lymphoblastic leukemia (B-ALL), rendering malignant cells resistant to the effects of CD22-directed immunotherapies, according to a recent study by researchers at Children’s Hospital of Philadelphia (CHOP). The findings could allow oncologists to screen new patients to see if their leukemic cells contain alternatively spliced CD22 mRNA variants, which could reveal which patients might not respond to anti-CD22 therapies and would need alternative treatment plans. The study was published in Blood Cancer Discovery, a journal of the American Association for Cancer Research.

Newswise: Computer Model of Blood Enzyme May Lead to New Drugs for Cardiovascular Disease
Released: 3-Jan-2022 4:05 PM EST
Computer Model of Blood Enzyme May Lead to New Drugs for Cardiovascular Disease
UC San Diego Health

Computer simulations from UC San Diego School of Medicine reveal the action mechanism and substrate specificity of an important blood enzyme. These findings open the door for new therapeutics against cardiovascular disease, and further support a unifying theory of phospholipase function.

Newswise: Researchers identify biomarker for depression, antidepressant response
Released: 3-Jan-2022 11:00 AM EST
Researchers identify biomarker for depression, antidepressant response
University of Illinois Chicago

Researchers have identified a biomarker in human platelets that tracks the extent of depression.

Newswise: World Renowned Geneticist and Sickle Cell Disease Expert Takes Helm of Genetic Medicine Department at Johns Hopkins
Released: 28-Dec-2021 9:00 AM EST
World Renowned Geneticist and Sickle Cell Disease Expert Takes Helm of Genetic Medicine Department at Johns Hopkins
Johns Hopkins Medicine

South African geneticist Ambroise Wonkam, M.D., Ph.D., D.Med.Sc., has been selected as Johns Hopkins Medicine’s director of the Department of Genetic Medicine and the McKusick-Nathans Institute of Genetic Medicine.

20-Dec-2021 7:30 AM EST
Study Confirms Nutrient’s Role in Childhood Blood Cancer
NYU Langone Health

A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute lymphoblastic leukemia, a new study shows.

Newswise: Could EKGs Help Doctors Use AI to Detect Pulmonary Embolisms?
Released: 21-Dec-2021 3:10 PM EST
Could EKGs Help Doctors Use AI to Detect Pulmonary Embolisms?
Mount Sinai Health System

Pulmonary embolisms are dangerous, lung-clogging blot clots. In a pilot study, scientists at the Icahn School of Medicine at Mount Sinai showed for the first time that artificial intelligence (AI) algorithms can detect signs of these clots in electrocardiograms (EKGs), a finding which may one day help doctors with screening.

   
Released: 17-Dec-2021 11:05 AM EST
New gene therapy could provide cure for sickle cell disease, according to UAB study
University of Alabama at Birmingham

Although unproven, this novel sickle cell therapy serves as a potential cure. More measures need to be taken to determine long-term function and organ improvement.

16-Dec-2021 12:00 PM EST
New potential treatment for graft-versus-host-disease and other inflammatory disorders
UC Davis Health (Defunct)

UC Davis Health researchers showed that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease, an inflammatory condition that develops in patients after their allogeneic hematopoietic stem cell transplantation.

Released: 15-Dec-2021 7:00 AM EST
Researchers Explore Potential Causes, Treatments for ‘Long COVID’ Complications
American Physiological Society (APS)

A new review explores the physiology behind and proposed management strategies for body-wide symptoms of the post-acute sequelae of SARS-CoV-2 (PASC), otherwise known as “long COVID.” The review is published ahead of print in the American Journal of Physiology-Cell Physiology.

Released: 14-Dec-2021 9:35 AM EST
For children, young adults with recurrent AML, immunotherapy shows promise
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that an immunotherapy harnessing pre-activated natural killer cells can help some children and young adults with recurrent AML and few other treatment options.

9-Dec-2021 10:55 AM EST
New Drug Combo May Improve Family-donated Stem Cells as Blood Cancer Treatment
NYU Langone Health

A drug combination can safely prevent transplanted stem cells (graft) from attacking the recipient’s (host) body, allowing them to develop into healthy new blood and immune cells, a new study shows.



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