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Selfish Gene Acts as Both Poison and Antidote to Eliminate Competition

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Researchers from the Stowers Institute for Medical Research in collaboration with Fred Hutchinson Cancer Research Center researchers have identified an unprecedented genetic survival strategy that would be right at home in an Agatha Christie murder mystery novel.

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Epigenetics, epigenetic reprogramming, genes, Adolescence, Binge Drinking, Brain Development, Brain Chemistry, Psychiatric Problems, early life experiences

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A reporter's PressPass is required to access this story until the embargo expires on 25-Jun-2017 9:00 AM EDT

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Cells, Aging, Telomeres, heaving drinking, biological aging, cellular level, telomere shortening, thiamine deficiency

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 25-Jun-2017 9:00 AM EDT

Medicine

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MYCN, Neuroblastoma, Pediatrics, Germline, Genetics

New Research Points to Potential for More Targeted Treatments of Deadly Neuroblastoma Tumors in Children

Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research by the University of Chicago Medicine. The findings lay the groundwork for developing more targeted treatments for particularly deadly variations of the cancer.

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Uniformed Services University Of The Health Sciences, Uniformed Services University, USU, Usuhs, National Institute Of Allergy And Infectious Diseases, National Institute for Alcohol Abuse and Alcoholism, Atopic Dermatitis, severe eczema

New Genetic Mutations Linked to Eczema

A genetic mutation could be the cause of severe eczema, according to new research published June 19 in Nature Genetics by researchers at the Uniformed Services University of the Health Sciences (USU). Researchers believe these new findings could influence new treatment strategies for the millions of individuals who struggle with this chronic condition.

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Human Genome

Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome

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Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a state-of-the-art gene-editing technology to advance the system’s ability to target, cut and paste genes within human and animal cells—and broadening the ways the CRISPR-Cpf1 editing system may be used to study and fight human diseases. 

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DNA-Cutting Enzyme, Drug for High-Risk Leukemias, Infant Sun Protection, and More in the Children's Health News Source

Click here for the latest research and features on Children's Health.

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Opthalmalogy, Wayne State University, Micrornas, Pseudomonas aeruginosa (PA)-induced keratitis

Wayne State Receives $1.9 M NIH Grant to Develop Novel Therapy for Corneal Bacterial Infection

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Wayne State University recently received a five-year, $1.925 million grant from the National Eye Institute of the National Institutes of Health to test the role of microRNAs (miRNAs) — a newly recognized level of gene expression regulation — in bacterial keratitis – an infection of the cornea caused by bacteria — as well as to identify new therapeutic targets and alternative treatment strategies.

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Developmental Biology And Molecular Biology, Whitehead Institute, Terry Orr-Weaver, Embryo Development, mRNA translation

Elegant Switch Controls Translation in Transition From Egg to Embryo

The transition from an egg to a developing embryo is one of life’s most remarkable transformations. Now Whitehead Institute researchers have used fruit flies to decipher how one aspect—control of the translation of messenger RNAs (mRNAs) into proteins—shifts as the egg becomes an the embryo. This type of switch could tell scientists more about how human cells work and embryos develop.

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Liver, Bioengineering, human pluripotent stem cells, Liver Disease, hepatic diseases, Tissue Engineering, Nature, Research, Transplant, Genetics, Genomics, Cincinnati Children's Hospital Medical Center, pediatrics disorders, news, press release, Bioengineered

Bioengineered Human Livers Mimic Natural Development

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An international team of researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ’s developmental processes – greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells. The scientists report online in Nature on June 14 that their bioengineered human liver tissues still need additional rounds of molecular fine tuning before they can be tested in clinical trials.







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