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Science

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Chemistry, Biochemistry, zinc, Fertilisation, Fertility, Bacterial Infection

Interview with a Scientist: Thomas O’Halloran, Metal Maestro

In a video interview, Thomas O’Halloran discusses the roles of metals in the body with a focus on how zinc regulates egg cell maturation and fertilization.

Medicine

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Breast Cancer, Hormone Therapy, adjuvant endocrine therapy , hormone-receptor-positive breast cancer

Under and Misuse of Hormone Therapy Decreasing, but Still High

A nationwide cancer registry of almost one million patients treated for hormone-sensitive breast cancer shows that one out of six women who should have received post-surgical treatment known as adjuvant endocrine therapy did not get this recommended component of care, which can reduce the odds of recurrence.

Medicine

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DSD, differences of sex development

Sex Development Center Stage in Special Journal Issue

Naveen Uli, MD, associate professor of pediatrics and Michiko Watanabe, PhD, professor of pediatrics at Case Western Reserve University School of Medicine served as editors for the special issue of Birth Defects Research Part C: Embryo Today.

Medicine

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disorder of sex development, DSD

When Sex Development Goes Awry: Is It a Girl or a Boy?

Standards of care are ever evolving, but now front-line pediatricians from Case Western Reserve University School of Medicine have assembled the latest data about the varied causes of DSD, complete with clinical vignettes and appropriate management plans.

Medicine

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Depression, Anxiety, Premature Babies, Functional Connectivity, MRI

Early Signs of Anxiety, Depression May Be Evident in Newborns

Early predictors of anxiety and depression may be evident in the brain even at birth, suggests a study at Washington University School of Medicine in St. Louis.

Medicine

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Prostate Cancer, radiotracers, Pet Scan, Cancer Diagnositics

New Radiotracer Could Make Diagnosing Prostate Cancer Faster and Easier

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Researchers at NIBIB have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial. Prostate cancer is the fifth leading cause of death worldwide and is especially difficult to diagnose. While prostate cancer is relatively easy to treat in its early stages, it is prone to metastasis and can quickly become deadly. In order to plan how aggressively they should treat the cancer, it is important for doctors to know how far the cancer has progressed. NIBIB researchers have attempted to solve this problem by developing a radiotracer that could identify prostate cancer at all stages.

Medicine

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Kimmel Cancer Center, Kala Visvanathan, Antonio Wolff, Sara Sukumar, arbs, Breast Cancer, Blood Test

Blood Test That Detects Changes in Tumor DNA Predicts Survival of Women with Advanced Breast Cancer

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Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels.

Medicine

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Temple, Temple University, Hospital, Grant, Grants, Opiods, Opiod, Science, Research, Pennsylvania, Philadelphia

Temple Launches Center of Excellence to Address Opioid Use in Pregnancy

Temple/Wedge Center of Excellence Funded by $500,000 State Grant

Medicine

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Premature Birth, Microbiome, Womens Health, Obstetrics, Gynecology, Penn Medicine, March Of Dimes

Bacteria in the Cervix May Be Key to Understanding Premature Birth

Depending on the specific type, bacteria in a woman’s vagina and cervix may increase the risk of premature birth or protect against it, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Results of the study provide groundbreaking information that the authors suggest could help physicians learn how to prevent preterm birth, either by eliminating the “bad” bacteria, or increasing the “protective” bacteria.

Medicine

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Bone Density, Menopause, Women's Health, Bone Structure, Bone Mass, Orthopedic, bone fragility

Examining Women’s Bones During Menopause May Help Head Off Fractures

Jepsen is the lead author on a new study, published in the Journal of Bone and Mineral Research, that examined the bone traits of 198 midlife women transitioning through menopause for 14 years. The goal: identifying women who will experience bone fragility well in advance of fracture.

Medicine

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Bidmc, Beth Israel Deaconess Medical Center, Obstertics, Quality & Patient Safety, Labor & Delivery, Quality Improvement

Hospital-Led Interventions Associated with Significant Reduction in Cesarean Rate

A new study led by clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that hospital-led interventions over a seven-year period were associated with a significant reduction in the hospital’s Cesarean delivery rate. During the intervention period, researchers found that the Cesarean rate for low-risk women having their first delivery decreased from 34.8 percent to 21.2 percent. The hospital’s overall Cesarean rate also declined from 40 percent to 29.1 percent over the same period.

Medicine

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practice management, Practice Management 2017, perioperative surgical home, anesthesia care team

App Helps C-Section Patients Reduce Length of Hospital Stay After Delivery

Women who used a smartphone app as part of a Perioperative Surgical Home (PSH) program were released from the hospital sooner after delivering their babies via cesarean section, according to a study presented at the American Society of Anesthesiologists PRACTICE MANAGEMENT 2017 meeting.

Medicine

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Dr. Juan Brito, Dr. Juan Brito Campana, Dr. Spyridoula Maraka, Endocrinology, Hypothyroidism, Hypothyroidism during pregnancy, kern center, Medical Research, Minnesota News Releases, news releases, OptumLabs, Preeclampsia, Pregnancy, Research, science of health care delivery, Subclinical Hypothyroidism, thyroid stimulating hormone, TSH

Should Hypothyroidism in Pregnancy Be Treated?

When a woman becomes pregnant, many changes occur in her body. One of those changes is in the levels of various hormones produced by the body.

Medicine

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New Study Shows Anxiety Impairing Quality of Life for Postmenopausal Women

Anxiety associated with hot flashes, sleep disruption, and muscle and joint complaints

Medicine

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Cervical Cancer, Hpv Vaccine, Pap Test

Roswell Park: Racial Disparities From Cervical Cancer Are a Wake-Up Call

Medicine

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Reproduction, Fertility, Down Syndrome, Biology, Cell Biology

Biologists Identify Reproductive "Traffic Cop"

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University of Iowa researchers have found a protein that regulates how chromosomes pair up and pass genetic information. FDK-6 dictates the speed at which maternal and paternal chromosome strands move and join in roundworms. The findings were published online this month in The Journal of Cell Biology.

Science

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Molecule, Prostate Cancer, Roswell Park Cancer Institute

Can Prostate Cancer Metastasis Be Stopped Before It Starts? Research Team Identifies Role for Particular MicroRNA

Metastasis, or spread of a tumor from the site of origin to additional organs, causes the vast majority of cancer-related deaths, but our understanding of the molecular mechanisms behind metastasis remains limited. A research team led by Dean Tang, PhD, Chair of the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute, examined the multistep process that leads to metastasis and their work, which illuminates the role of prostate cancer stem cells that promote tumor growth and metastasis, has been published online ahead of print in the journal Nature Communications.

Medicine

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Herpes Simplex Virus 2, vaccine candidates, PLoS Pathogens

New Genital Herpes Vaccine Candidate Provides Powerful Protection in Preclinical Tests

Approximately 500 million people around the world are infected with the genital herpes virus known as herpes simplex virus 2 (HSV2). A vaccine that could bring an end to this global pandemic is needed desperately, yet no candidate vaccine has ever performed well in clinical trials. Now scientists in the Perelman School of Medicine at the University of Pennsylvania have shown that a new type of vaccine provides powerful protection in standard guinea pig and monkey models of HSV2 infection.

Medicine

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genetic counselors, prenatal screening, non-invasive prenatal screening, Frank Boehm, Martha Dudek, cell-free fetal DNA screening, Obstetrical Genetic Counseling, Vanderbilt, Vanderbilt University Medical Center

Non-Invasive Prenatal Screening’s Popularity on the Rise

Genetic counselors are playing a greater role in areas of medicine in the wake of advancement in genomic technology. In the last decade, genetic testing has improved dramatically, enabling medical professionals the ability to screen for common genetic conditions like Down syndrome more accurately beginning at 10 weeks gestation.

Medicine

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Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Postpartum Depression, Gestational Diabetes, risk factors for depression, Pregnacy, Maternal Health, gestational diabetes research, Depression, Depression and Diabetes, depression and women

Gestational Diabetes Increases Risk for Postpartum Depression

Researchers from the Icahn School of Medicine at Mount Sinai and the Karolinska Institutet have found that gestational diabetes raises the risk of postpartum depression in first-time mothers.







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