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Medicine

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DNA, Dna Repair, Cellular Aging, Mysteries of Aging, Dna Damage, Molecule NAD, Repairing DNA, Cell Ageing, Harvard Medical School Scientists, NAD, NMN, Sirt1, PARP1, DBC1, Genetics, protein binding, David Sinclair

Harvard Medical School Scientists Pinpoint Critical Step in DNA Repair, Cellular Aging

The body’s ability to repair DNA damage declines with age, which causes gradual cell demise, overall bodily degeneration and greater susceptibility to cancer.

Science

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Biology, Regenerative Medicine, regenerative biology

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 30-Mar-2017 6:00 AM EDT

Medicine

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Seth Margolis, Alzheimer’s, ephexin5 , Brain, Amyloid

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Mar-2017 4:00 PM EDT

Science

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Alzheimber's Disease, Neurochemistry

Researchers Focus on Cell Membranes to Develop Alzheimer's Treatments

Thin parts of the cell membranes of neurons turn out to be particularly vulnerable to a protein that collects in the brain of people with Alzheimer's disease, according to a University of Michigan researcher.

Medicine

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Cystic Fibrosis, Mucus

The Mechanism of Mucus: Discovery Could Lead to Better Cystic Fibrosis Treatments

kesimer_mucus_compact.jpg

University of North Carolina scientists found that mucin proteins, which make mucus thick and sticky, fail to unfold properly in the airways of people with cystic fibrosis. And they found the lack of water in the lung can trigger the misfolding mucins.

Medicine

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multiple sclerosis, Neurodegenative Disease, Neurodegeneration, Research, Experimental Treatment, Cincinnati Children's Hospital Medical Center, Developmental Cell, Children, National Multiple Sclerosis Society, National Institutes For Health

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Mar-2017 12:00 PM EDT

Medicine

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Zinc in the Retina May Indicate A New Way to Protect and Regenerate the Optic Nerve in Glaucoma Patients

Connecting pieces of information by finding a common thread often takes glaucoma researchers in unexpected directions. Zinc is one such thread that joined together different experts at Boston Children’s Hospital and Harvard Medical School.

Medicine

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Pavlovian response, NEURON ACTIVITY, Alzheimer's Disease, Parkinson's Disease, Tourette Syndrome, Learning

Study Identifies Brain Cells Involved in Pavlovian Response

UCLA scientists have traced the Pavlovian response to a small cluster of brain cells -- the same neurons that go awry during Huntington’s disease, Parkinson’s disease and Tourette syndrome. The research could one day help scientists find new approaches to diagnosing and treating these neurological disorders.

Science

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Tree Of Life, Cornell University, Taxonomy, Ecology & Evolution, Ecology, Evolutionary Biology, Biodiversity

Cornell Evolutionary Biologist Explains How to 'Walk the Tree of Life'

Harry Greene, professor of ecology and evolutionary biology at Cornell University, and Cissy Ballen of the University of Minnesota have just published a paper in PLOS Biology, “Walking and Talking the Tree of Life: Why and How to Teach About Biodiversity,” discussing why the evolutionary TOL approach to biodiversity is best, to what extent the traditional taxonomy is still used and how to teach TOL using an active learning approach.

Science

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Membrane Fusion, Cell Biology, Snare, molecular biology of the cell, American Society For Cell Biology

New Cell Membrane Fusion Model Challenges Dogma

MembraneFusioninYeastandHumans.jpg

Membrane fusion lies at the heart of many cell functions—from the secretion of antibodies to the release of neurotransmitters. For more than two decades, one view of the process by which membrane fusion occurs has been accepted as dogma; now recent studies indicate that fusion is more complex. These discoveries are being regarded by at least one leading cell biologist as “textbook changing” and could alter how we develop drugs that affect membrane fusion activities.







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