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Medicine

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Society Of Toxicology, Toxicology, toxicologist, Annual Meeting, ToxExpo, data science, Precision Medicine, Epigenetic, Food Safety, Arsenic, Pesticide, Alternative Test Methods, Public Health, In Vitro, Organs-on-a-chip, Carcinogenesis, Air Pollution

Latest Research on Data Science, Precision Medicine, Epigenetics, Food Safety, Arsenic, Pesticides, Alternative Test Methods, and More Featured at SOT 56th Annual Meeting and ToxExpo

The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.

Medicine

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laboratory technology, cell reprogramming, Precision Medicine, Cancer Drug, Cells

Scientists Describe Lab Technique with Potential to Change Medicine and Research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

Medicine

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pulmospheres, Pulmonary, IPF, Idiopathic Pulmonary Fibrosis, Precision Medicine

Precision Medicine: UAB Study Creates ‘Mini-Lung’ to Study Effect of Pulmonary Fibrosis Drugs

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Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from UAB presented today in JCI Insight.

Medicine

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Breast Cancer, Ovarian Cancer, Prostate Cancer, olaparib, PARP inhibitors, Metabolism, Lung Cancer

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

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Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study “Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells,” which has been published in The Journal of Cell Biology, suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

Medicine

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pediatric endocrinology, Growth Hormone Deficiency, growth hormone treatment, IGF-I deficiency, Idiopathic Short Stature, ISS, Children's Hospital Of Philadelphia, Medical Ethics

When Should Doctors Treat Short Children and Teens with Growth Hormone?

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When is it appropriate to treat short children with growth hormone? The answer is not always clear-cut, as many parents and physicians weigh social, medical and ethical concerns. Experts in pediatric endocrinology have issued a new set of guidelines for managing children and teens who have growth failure.

Medicine

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Drug Discovery

Robert R. Meyer Foundation Gift Boosts Drug Discovery Efforts

The Robert R. Meyer Foundation is supporting Southern Research’s Drug Discovery program with a $500,000 gift that aims to accelerate efforts to find new treatments for unmet medical conditions and rare and neglected diseases.

Science

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A Quark Like No Other, Biophysics Plays Key Role in Immune System Signaling and Response, ALMA Reveals Sun in New Light, and MORE in the Physics News Source Sponsored by AIP

Click here to go directly to the Physics News Source Sponsored by AIP.

Medicine

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Wayne State University, NIH, Tinnitus, Otolaryngology

Wayne State University Research Team Develops New Diagnostic Tool to Identify Tinnitus in Animals

A team of researchers from Wayne State University has developed a behavioral tool that may significantly aid in understanding the underlying mechanisms of tinnitus, ultimately leading to new drugs and treatment methods.

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New TSRI Method Could Turbocharge Drug Discovery, Protein Research

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A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins.

Medicine

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protien, Drug Development, Disease Progression

Structure of Atypical Cancer Protein Paves Way for Drug Development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

Medicine

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Best Treatment Option Written in Cancer's Genetic Script

Acute myeloid leukaemia study finds personalised therapy is possible.

Science

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Genetics, Genome, Human Genome Sequence, Precision Medicine, Disease Risk, Genetic Predisposition, UTHealth , boerwinkle

UTHealth Study Outlines Framework for Identifying Disease Risk in Genome Sequence

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– Imagine a day when you visit the doctor’s office for your annual physical. Your physician orders routine tests – cholesterol, glucose and blood count – but they also order a sequence of your genome, all 3 billion letters of it. Routine genomic testing is not far away, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

Medicine

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Pharmaceutical Industry, Drug Development

Now Entering 'the Valley of Death'

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Amid Trump comments and stock dive, let WUSTL expert on the history of the pharmaceutical industry Michael Kinch walk you through pharma "Valley of Death."

Medicine

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Warfarin, Blood Thinner, EHR

Changes to Hospital Electronic Health Records Could Improve Care of Patients on Popular Blood Thinner

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Warfarin is a commonly prescribed blood thinner used to prevent harmful blood clots. However, the drug requires frequent monitoring, daily dosing and can result in serious negative effects when mixed with vitamin K, a vitamin commonly found in vegetables such as lettuce or broccoli. Now, a new study from University of Missouri Health Care has found that using electronic health records (EHR) can improve the care patients receive after they leave the hospital and eliminate potential confusion among care providers and pharmacists.

Medicine

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Fundraiser, Billion dollar campaign, Billion Dollar Challenge, The Princess Margaret Cancer Foundation., princess margaret cancer centre, University Health Network

The Princess Margaret Successfully Achieves Historic Billion Dollar Challenge for Personalized Cancer Medicine

The Princess Margaret Cancer Foundation is thrilled to announce the successful achievement of our Billion Dollar Challenge, in partnership with the Princess Margaret Cancer Centre at University Health Network.

Medicine

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Cytomegalovirus, Microbiology And Immunology

Researchers Develop New Compound to Fight Cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus, human cytomegalovirus (CMV) from reproducing and protect immunocompromised patients, like those with HIV, on chemotherapy, with transplants and infants from the effects of the disease, according to Penn State College of Medicine researchers.

Medicine

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Diabetes, Insulin, Metabolic Disease, T1D

Case Western Receives $2.5 Million Helmsley Grant for “Smart” Insulin Development

The Leona M. and Harry B. Helmsley Charitable Trust awarded a $2.5 million grant to the Case Western Reserve University School of Medicine to continue research on a new form of insulin for those living with type 1 diabetes (T1D).

Medicine

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Prostate Cancer, Prostate, genes, Precision Medicine, princess margaret cancer centre, University Health Network

Prostate Cancer Researchers Discover Genetic Fingerprint to Identify How and When Disease Initially Spreads

Canadian prostate cancer researchers have discovered the genetic fingerprint that explains why up to 30 per cent of men with potentially curable localized prostate cancer develop aggressive disease that spreads following radiotherapy or surgery.

Medicine

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Prostate Cancer, Prostate, genes, BRCA2 gene, BRCA2 gene mutation, prostate cancer therapy, princess margaret cancer centre, University Health Network

Prostate Cancer Team Cracks Genetic Code to Show Why Inherited Disease Can Turn Lethal

Canadian and Australian prostate cancer researchers have discovered a key piece in the genetic puzzle of why men born with a BRCA2 mutation may develop aggressive localized cancers that resist treatment and become lethal for up to 50 per cent of patients within five years.

Medicine

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Parkinson Disease, DBS, Deep Brain Stimulation

Experimental Treatment for Parkinson's Symptoms Shows Promise

More than 12 months after Parkinson's patient Bill Crawford received "DBS Plus," he can walk more easily and is back to leading services at his beloved Porter Memorial Church in Lexington, Ky.







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