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Medicine

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Cancer, oropharngeal cancer, Throat Cancer, Head And Neck Cancer, HPV, HPV and cancer, biomarkers, Cancer Recurrence

Predicting Throat Cancer Recurrence with a Blood Test

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Researchers found that patients whose oropharyngeal cancer recurred had higher levels of antibodies for two proteins, E6 and E7, which are found in HPV-fueled cancers. The finding suggests a potential blood-based marker that could predict when cancer is likely to return.

Medicine

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Blood Cancers, Cancer, Chinese Herbal Medicine, Chemotherapy side effects, Radiation Therapy For Cancer, oncology care

Chinese Herbal Treatment Shows Signs of Effectiveness in Bone Marrow Recovery UCLA Research Alert

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Researchers have found that a Chinese herbal regimen called TSY-1 (Tianshengyuan-1) TSY-1 increased Telomerase activity in normal blood cells but decreased it in cancer cells. Telomerase is an enzyme responsible for the production of telomeres, which play an important role in the regulation of normal cell division. These results indicate that Telomerase-based treatments may be of significance in treatments for both blood cell deficiency and cancer.

Business

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Cancer, Cancer Care, Cancer Research, Cancer Care And Cancer Research, Hematologic Cancers, Lymphoma, Lymphoma Research, Clinical Trials, Phase I Clinical Trial, Phase I Clinical Trials, Multiple Myeloma, Leukemia, CAR T cell, CAR T-cell therapy, Immunotherapy, Cancer Treatment, Memorial Sloan Kettering, Memorial Sloan Kettering Cancer Center, New Jersey, Co

Memorial Sloan Kettering and Hackensack Meridian Health Announce Cancer Care Partnership

Memorial Sloan Kettering Cancer Center and Hackensack Meridian Health announced the Memorial Sloan Kettering–Hackensack Meridian Health partnership, a joint venture that will combine both organizations’ unparalleled expertise in all areas of cancer care and research to accelerate new discoveries and improve the lives of patients they jointly serve.

Medicine

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ASH 2016: Tackling Blood Cancers with Immunotherapy

This Saturday [Dec 3], the 58th Annual Meeting of the American Society of Hematology will begin in San Diego, where the latest advances in research for blood cancers including leukemia, lymphoma, and myeloma will be highlighted during the four days of talks and poster presentations.

Medicine

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Aaron Milstone, James Fackler, Blood, draw, Cultures, Sepsis, Fever, Pediatrics, Pediatric

New Blood Draw Protocol Could Minimize Risk for Critically Ill Children

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Johns Hopkins researchers report that implementing a checklist-style set of procedures appears to cut almost in half the number of potentially unnecessary blood culture draws in critically ill children without endangering doctors' ability to diagnose and treat life-threatening blood infections.

Medicine

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psorias, Thrombosis, Blood Clot, IL-6

Immune System’s “Workaround” May Explain Heart Disease in Psoriasis Patients

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Two new studies out of Case Western Reserve University School of Medicine describe how the inflammatory response to psoriasis can alter levels of several immune system molecules, ultimately increasing a person’s risk of thrombosis, which can include fatal blood clots

Medicine

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Emergency Medicine, Blood

New Trial to Examine Use of Pre-Hospital Blood Products

University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) to support a ground-breaking new study to investigate the effectiveness of giving patients blood products immediately after a major injury or trauma - before they reach hospital.

Medicine

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AML, Cancer Vaccine, Beth Israel Deaconess, Beth Israel Deaconess Medical Center, David Avigan, Jacalyn Rosenblatt, Acute Myeloid Leukemia (AML)

Personalized Cancer Vaccine is Associated With Promising Outcomes for Patients with Acute Myeloid Leukemia

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center (BIDMC). The product of a long-term collaboration among investigators at the Cancer Center at BIDMC and Dana-Farber Cancer Institute, the vaccine stimulated powerful immune responses against AML cells and resulted in protection from relapse in a majority of patients, the team of researchers reported today in Science Translational Medicine.

Medicine

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Antibiotics, Blood, Purification, Magnetic

"Pulling" Bacteria Out of Blood

Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets. The initial laboratory tests at Empa in St. Gallen have been successful, and seem promising.

Medicine

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Organs-on-a-chip, Brain, blood-brain barrier, neurovascular networks, Drug Testing

Blood-Brain Barrier on a Chip Sheds New Light on “Silent Killer”

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The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds. An interdisciplinary team of researchers from the Vanderbilt Institute for Integrative Biosystems Research and Education (VIIBRE) headed by Gordon A.

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Researchers Study Watermelon's Effect on Blood Vessels

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University of Alabama researchers are recruiting for a 10-week study to see how watermelon impacts blood vessel function.

Medicine

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Neal Fedarko, Peter M. Abadir, Peter Abadir, Autoantibody, Blood, Angiotensin

New Link Discovered Between Class of Rogue Autoantibodies and Poor Health Outcomes

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Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. In a report on the work, published online in the journal Circulation on Nov. 30, the team says a large class of common blood pressure drugs that target the angiotensin receptor, called angiotensin receptor blockers (ARBs), may help patients depending on the levels of the autoantibodies.

Medicine

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Acute Myeloid Leukemia

CPX-351 Improves Survival Following Allogeneic Hematopoietic Cell Transplant in Older High-Risk Acute Myeloid Leukemia Patients, Says Moffitt Cancer Center Physician

Analysis of a phase 3 trial shows that older patients with high-risk or secondary AML, who received initial treatment with CPX-351, had improved survival following allogeneic hematopoietic cell transplant, when compared with patients who received standard 7+3 cytarabine and daunorubicin as initial therapy.

Medicine

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myelodysplastic syndromes (MDS)

Moffitt Cancer Center Study Shows Improved Response Rates in Myelodysplastic Syndromes Patients Treated with Lenalidomide and Epoetin Alpha

Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia. Many patients with lower-risk MDS benefit from treatment with recombinant-erythropoietin (rHuEPO), which stimulates blood cell production.

Medicine

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ASH Conference, Hematologic Cancers, Blood Cancers, Lymphoma, Leukemia, Myeloma

City of Hope Experts Can Discuss ASH Studies on Blood Cancers

Medicine

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Anesthesia, Analgesia, zika, zika virus, Blood Transfusions, Disease, Blood Disease, Zika infection

Preventing Zika From Blood Transfusion—Steps to Reduce Transfusion Needs Will Also Lower Zika Risk

As the Zika epidemic spreads to the United States, the potential for contracting the disease via blood transfusion has emerged as a serious concern. The problem of transfusion-related Zika virus transmission—and recommended strategies to reduce that risk—are outlined in a special article in Anesthesia & Analgesia. Anesthesia & Analgesia is published by Wolters Kluwer.

Medicine

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Abdominal Aortic Aneurysm, vascular surgeons, Vascular Surgery, Endovascular Abdominal Aortic Aneurysm, endovascular surgery, UAB Medicine, University of Alabama at Birmingham

Surgery or Not – UAB Physician Says the Health Care System and Reimbursement Model Decide in Treating Abdominal Aortic Aneurysm

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A ruptured abdominal aortic aneurysm is the 15th leading cause of death in the country, and the 10th leading cause of death in men older than 55.

Medicine

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shear accumulation, Blood Thinners, Computational Fluid Dynamics modeling, Blood Clots, stent grafts, thoracoabdominal aneurysm, Food And Drug Administration, Sanford Health, South Dakota State University

Fluid Flow Model Evaluates Clotting Risk in New Stent Graft Design

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Whether patients with mechanical heart valves or left ventricular assist devices must take blood thinners depends on how effectively blood flows through these implantable devices. Researchers have modeled the flow of blood through these devices to estimate clotting risk, but this type of work has not been done on stent grafts—until now. The results showed that shear accumulation in a new endovascular stent graft design was comparable to that of an idealized aorta.

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Tighter Blood Pressure Control May Save More Than 100,000 Lives Each Year in the U.S.

• New research estimates the projected lives that would be saved if patients at high risk of cardiovascular disease underwent intensive blood pressure lowering. • The findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Weight Loss May Help Prevent Multiple Myeloma

Carrying extra weight increases a person's risk that a benign blood disorder will develop into multiple myeloma, a blood cancer. This is particularly true for older, African-American men.







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