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Medicine

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Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, zika virus, Dengue Fever, West Nile, Zika research, South America, Flavivirus, Disease Transmission, Disease Risk, Infectious Disease

Pre-Existing Immunity to Dengue and West Nile Viruses May Cause Increased Risk in Zika-Infected

As the Zika virus continues to spread rapidly across the globe, it might pose a particular risk to people previously infected with two related viruses, dengue and West Nile, researchers at the Icahn School of Medicine at Mount Sinai have found. Their study, published in the journal Science, may help explain the severe manifestations of Zika virus infection observed in specific populations, including those in South America.

Medicine

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Ebola Virus, Institute for Biomedical Sciences, Georgia Research Alliance, National Institutes of Health, National Institute Of Allergy And Infectious Diseases, drug

Georgia State Researcher Gets $4.1 Million Federal Grant to Develop Drug to Combat Ebola Virus

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Dr. Christopher Basler, a professor in the Institute for Biomedical Sciences at Georgia State University, director of the university’s Center for Microbial Pathogenesis and a Georgia Research Alliance Eminent Scholar in Microbial Pathogenesis, has received a five-year, $4.1 million federal grant to develop a drug targeting Ebola virus.

Medicine

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Ebola, Infectious Diseases, Infectious Disease, HHS, ASPR, NETEC

Ebola Grant Expanded From $12 Million to $24 Million

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Supplemental funding will allow three partner institutions to perform additional site visits, conduct more education and training courses, as well as build a special pathogens research network.

Medicine

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Ebola, Vaccine

UF Plays Key Role in Trial for Successful Ebola Vaccine

An international group of researchers associated with the World Health Organization has published its final report on the Ebola vaccine trial in Guinea, finding that the vaccine is a safe and effective way to prevent Ebola infection.

Medicine

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Ebola, Vaccine, Trial, emerging disease

Trial Results Confirm Ebola Vaccine Provides High Protection Against Disease

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to a new study that included researchers from the University of Maryland School of Medicine.

Science

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Ebola, Ebola virus disease, ebola drug

Collaborations Pharmaceuticals, Inc. And Texas Biomed Announce NIH Award to Develop a Treatment for Ebola

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The National Center for Advancing Translational Sciences (NCATS) recently awarded $596,533.00 to Collaborations Pharmaceuticals, Inc. (CPI) to initiate a partnership with Texas Biomedical Research Institute aimed at repurposing an antimalarial for use against the Ebola virus.

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Science

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Ebola, Genome, Virus, Mutation, Glycoprotein, Amino Acid, San Diego, La Jolla, Sequencing, STSI

New TSRI Study Suggests Ebola Can Adapt to Better Target Human Cells

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A new study co-led by scientists at The Scripps Research Institute (TSRI) suggests that Ebola virus gained a genetic mutation during the 2013–16 epidemic that appears to have helped it better target human cells.

Medicine

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mosquito-borne viruses, , zika, dengue, chikungunya

Sociol-Ecological System Approach Leads to New Information in Study of Mosquito-Borne Viruses

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In an article published online Sept. 13 in UGEC Viewpoints , Upstate Medical University researcher Anna Stewart Ibarra, PhD, MPA, describes how a collaborative approach by researchers of varying disciplines is being used as a framework for studying the mosquito-borne viruses, zika, dengue and chikungunya.

Medicine

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Ebola, Ebola Antibody, Ebola Antibodies, Ebola vaccine, Ebola Vaccines, Ebola Virus, Ebolavirus, Antibody Engineering

New ‘Trojan Horse’ Antibody Strategy Shows Promise Against All Ebola Viruses

In research published in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles’ heel shared by all known types of Ebola virus. Two antibodies developed with this strategy blocked the invasion of human cells by all five ebolaviruses. The team included scientists from Albert Einstein College of Medicine, U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Integrated Biotherapeutics, Vanderbilt University Medical Center, and The Scripps Research Institute.

Medicine

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Ebola, Immunology, Vaccines, antibody deficiency, Drug Coated Stents, ZMapp, Structural Biology, cryo-electron microscopy

TSRI Scientists Pinpoint Ebola’s Weak Spots

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Scientists at The Scripps Research Institute now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus.







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