When melanoma turns metastatic, it spreads to the brain in more than 40% of patients. Published today in the Journal of Clinical Oncology (JCO), a study by Yale Cancer Center researchers show a checkpoint inhibitor immunotherapy drug has meaningful benefit for these patients.
Dermatologists routinely engage in the care of patients with mucocutaneous manifestations of Human Papillomavirus infections [HPV]. HPV is associated with protean medical illnesses including cervical, vaginal, vulvar, penile, anal, and oropharyngeal cancers, as well as warts
This month's Fred Hutch tip sheet includes story ideas about understanding how skin stops tumor growth, advances in studying Kasposi sarcoma, and forecasting the flu. To pursue any of these stories ideas, contact the person listed.
With the growing awareness of ultraviolet (UV) exposure resulting in an increased risk of photoaging and skin cancers, consumers are using higher sun protection factor (SPF) sunscreens with frequent reapplication. New research, Evaluation of Reapplication and Controlled Heat Exposure on Oxybenzone Permeation from Commercial Sunscreen Using Excised Human Abdominal Skin, presented today at the 2018 American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 Meeting demonstrates that heat and reapplication influences different sunscreen products containing the same amount of a key ingredient, oxybenzone, potentially affecting safety and toxicity of the UV filters included in sunscreens.
New research shows how metastatic melanoma becomes resistant to a common class of targeted therapy.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
The American Academy of Dermatology’s “Guidelines of care for the management of primary cutaneous melanoma" outline best practices for treatment of the disease. Developed by an expert work group, the guidelines are based on the latest available evidence.
Researchers at the George Washington University found skin cooling methods may be the best preventative intervention against taxane-based chemotherapy side effects.
As many as 16.5 million adults in America suffer from a skin disease known as atopic dermatitis, an inflammatory disease that results in red, itchy skin. The estimate comes from a new study from the Perelman School of Medicine at the University of Pennsylvania, which also projected 6.6 million of these adults have disease that would be classified as moderate to severe, leading to a decrease in quality of life.
Study suggests close observation is a reasonable management strategy for moderately dysplastic moles, but certain patients require continued screening for risk for melanoma
A new study published in Nature Communications shows that a molecular symbiosis between BAP1 and ASXL2 proteins can suppress cancerous tumors.
Can the combination of radiation therapy with an oncolytic virus treatment better boost the body’s immune response to melanoma than either treatment on its own? Investigators from Rutgers Cancer Institute of New Jersey further explored that question in work presented at the ASTRO Annual Meeting.
Navitoclax plus A-1210477 not only killed melanoma cells, but also killed the melanoma initiating cells (aka cancer stem cells) that often resist therapy.
Charis Curbo says most of the time she doesn’t think about her NF1 and the thousands of tumors coating her back, her trunk, and other areas of her skin. “I’m just who I am. I’ll wear tank tops no matter what.”
Contrary to the advice most cancer patients receive when they go through radiation treatment, topical skin treatments, unless applied very heavily, do not increase the radiation dose to the skin and can be used in moderation before daily radiation treatments.
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified a SCC-specific protein complex activated by TP63 and SOX2 which triggers a gene cascade that promotes SCC growth.
Drug-releasing textiles could, for instance, be used to treat skin wounds. Empa researchers are currently developing polymer fibers that can be equipped with drugs. The smart fibers recognize the need for therapy all by themselves and dose the active ingredients with precision and accuracy.
Researchers have developed techniques to detect Lyme disease bacteria weeks sooner than current tests, allowing patients to start treatment earlier.
On Sat., Sept. 29, more than 200 dermatologists, skin cancer survivors and their families and friends hiked four miles at Busse Woods to tell “Skin Cancer, Take a Hike!” Together, they raised more than $41,000 for SPOT Skin Cancer™ to benefit the American Academy of Dermatology’s skin cancer prevention and detection programs, including free skin cancer screenings, sunscreen dispensers, and permanent shade structures where children learn and play.
Nail polishes with ‘n-free’ labels are not necessarily free of toxic compounds
TMA is pleased to announce they have awarded three new myositis research grants.
Although hot water and bubble baths may sound relaxing to many, for those with atopic dermatitis, this can have the opposite effect, causing dry, scaly, red patches to develop on the skin. Affecting nearly 28 million Americans, atopic dermatitis, also known as eczema, is frequently described as the “itch that rashes.” Since the condition makes it harder for the skin to keep out harmful bacteria, viruses and other germs, people with eczema often have sensitive skin prone to inflammation and infections. Although there is no cure for eczema, dermatologists from the American Academy of Dermatology say those with moderate to severe eczema can improve their symptoms and reduce their risk of skin infections using bleach bath therapy.
Next time you’re stung by a wasp or a honeybee, consider the elegantly designed stinger that caused you so much pain. In a new study, researchers found that the stingers of the two species are about five times softer at the tip than at the base to make it easier to pierce your skin.
New research from the Keck School of Medicine of USC finds that an online care delivery model is equivalent to in-person care for improving psoriasis symptoms.
When patients present to providers in North Carolina for a possible tick bite, clinicians are not testing them for Ehrlichia, a tick-borne illness that occurs more frequently than Lyme disease and as frequently as Rocky Mountain Spotted Fever.
The odds of a black or Hispanic patient visiting an outpatient dermatologist are about half that of a white patient with the same skin condition, according to a new study in JAMA Dermatology. Patients most likely to receive outpatient dermatologic services in the study were white, educated women. The findings are among several that describe disparities in the use of outpatient dermatology services.
A compound secreted in the bloodstream could be the key factor that causes wounds in older people to heal with less scarring than in younger people.
Skin cancer is the most common cancer in the United States, affecting one in five Americans during their lifetime. To help raise awareness of skin cancer prevention and detection, the American Academy of Dermatology will host Skin Cancer, Take a Hike!™ – Chicago on Sat., Sept. 29 in Elk Grove Village. The scenic, four-mile walk at Busse Woods—part of the AAD’s SPOT Skin Cancer™ campaign to create a world without skin cancer—will benefit skin cancer prevention and detection programs, including free skin cancer screenings, sunscreen dispensers, and permanent shade structures where children learn and play.
Jules Lipoff, MD, an assistant professor of Clinical Dermatology at Penn, talks about what makes medicine so compelling for TV drama.
A team led by Marc Ernstoff, MD, of Roswell Park Comprehensive Cancer Center found that a drug complex containing IL-15 is both safe and well tolerated in patients with advanced solid tumors.
Prof. Yardena Samuels of the Weizmann Institute, working with a global team, has developed a way to target a patient's unique melanoma cells. The immunotherapy creates, in effect, a new drug for each person.
Using genetic and pharmacological means, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) were surprised to find that blocking LDHA had only a limited impact on melanoma cells, since they were able to redirect energy production. Their results identify an alternative growth pathway driven by a molecule called ATF4, revealing new potential targets for drug development. The study was published today in EMBO Journal.
If you’ve ever gone to bed with clear skin and woken up with a massive, painful pimple on your face, you’re not alone. According to dermatologists from the American Academy of Dermatology, acne is the most common skin condition in the United States, affecting up to 50 million Americans annually. Although acne comes in many forms, including blackheads and whiteheads, the most severe type of acne is a pimple that develops deep in the skin, causing a red, swollen and painful bump. Fortunately, say dermatologists, there are ways to tackle this type of acne at home to alleviate pain and reduce the pimple’s size, swelling and redness.
Mayo Clinic physicians Matthew Block, M.D., Ph.D. and Tina Hieken, M.D., have received a Stand up to Cancer (SU2C) Catalyst Award to fund melanoma research and a neoadjuvant clinical trial.
Being a teenager can be tough. Teens must manage high school and the pressures of adolescence while at the same time battling stubborn acne.
The latest research, features and announcements in healthcare in the Healthcare News Source
Patient satisfaction after plastic surgery is most affected by surgeon-related factors, such as taking the time to answer questions and including patients in the decision-making process, reports a study in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Chiggers, redbugs, harvest mites – whatever you call them, they are pesky little bugs whose bites cause really itchy rashes, usually around the ankles and waistline.
The stigma associated with the autoimmune disease psoriasis may lead people to avoid patients who show signs of the condition, including not wanting to date, shake hands, or have people in their homes if they suffer from the disease. New multidisciplinary research involving both psychologists and dermatologists from the Perelman School of Medicine at the University of Pennsylvania is the first to examine how common this stigma may be among the general population of the United States as well as among medical students.
Scientists at The University of Texas at El Paso have received nearly $6 million from the National Institutes of Health (NIH) to improve treatment and develop new diagnostic tools to assess post-therapeutic outcomes for patients with Chagas disease.
Michael Kolodney, who chairs West Virginia University’s Department of Dermatology, has developed a smartphone app to cultivate that intuition in medical students sooner. An initial study suggests that the app, called Skinder, may improve how accurately medical students diagnose melanomas.
A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer.
The University of Alabama at Birmingham has been awarded nearly $18.9 million by the National Institutes of Health Countermeasures Against Chemical Threats Program and National Institute of Environmental Health Sciences to support the UAB Research Center of Excellence in Arsenicals.
O uso de barro ou argila úmida como tratamento de pele tópico ou emplastro é uma prática comum em algumas culturas e o conceito de usar argila como medicamento vem dos tempos antigos. Agora, pesquisadores da Mayo Clinic e seus colaboradores na Arizona State University descobriram que pelo menos um tipo de argila pode ajudar a combater bactérias causadoras de doenças em feridas, incluindo algumas bactérias resistentes a tratamento. Os resultados foram publicados no International Journal of Antimicrobial Agents.
روشستر، مينيسوتا. -- يعتبر استخدام الطين أو الطين الرطب كعلاج جلدي موضعي أو كضمادة من الممارسات الشائعة في بعض الثقافات، ويعود مفهوم استخدام الطين كدواء أقدم العصور. في الوقت الحاضر، وجد باحثو Mayo Clinic والمتعاونون معهم بجامعة ولاية أريزونا أن نوعًا واحدًا على الأقل من الطين قد يساعد في مكافحة البكتيريا المسببة للأمراض في الجروح، بما في ذلك بعض البكتيريا المقاومة للعلاج. تظهر النتائج في المجلة الدولية المتعلقة بالعوامل المضادة للميكروبات..
Maple trees are best known for their maple syrup and lovely fall foliage. But it turns out that the beauty of those leaves could be skin-deep — and that’s a good thing. Today, scientists report that an extract from the leaves may prevent wrinkles.
Many parents worry that teens may not consider potential health risks, how a tattoo may impact them professionally or the chance that as they age and mature, they may regret getting a permanent tattoo.
Researchers from the George Washington University published an article in Trends in Parasitology outlining their lessons learned while creating vaccine candidates for hookworm and schistosomiasis.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right