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Medicine

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Labor Induction, Obstetrics & Gynecology, Penn Medicine, Misoprostol, Oxytocin, Childbirth, Health Care Costs

Drug/Catheter Combination for Labor Induction Could Save Women 2.4 Million Hours of Labor Annually, Penn Study Shows

Labor induction is one of the most common medical procedures in the world, with nearly one-quarter of women who deliver in the U.S. undergoing the procedure each year (totaling roughly 1 million). Despite its widespread use, labor induction is costly and still has no widely accepted “best practice.” Now, new research from the Perelman School of Medicine at the University of Pennsylvania is showing what may be the best available method for inducing labor, which may be necessary under circumstances including medical conditions such as preeclampsia, gestational diabetes or other health risks to the mom or baby.

Medicine

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Kimmel Cancer Center, AbbVie, Cancer, Urology

AbbVie and Johns Hopkins to Collaborate on Cancer Research

North Chicago, Ill. and Baltimore, Md. December 5, 2016 – AbbVie (NYSE: ABBV), a global biopharmaceutical company, and the Johns Hopkins University School of Medicine today announced that they signed a five-year collaboration agreement with the goal of advancing medical oncology research and discovery at both organizations.

Medicine

Science

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Sperm, Biomedical Engineering, Enzymes

Fast, Efficient Sperm Tails Inspire Nanobiotechnology

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Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style. That’s according to scientists at Cornell’s Baker Institute for Animal Health, the first team to recreate a 10-step biological pathway with all the enzymes tethered to nanoparticles.

Medicine

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Menopausal Women, Lung Function Decline, Lung Function, Shortness Of Breath, lung function testing, Menopause

Lung Function Decline Accelerates in Menopausal Women

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Menopausal women appear to experience an accelerated decline in lung function, according to new research published online ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

Medicine

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Endocrine Society, Journal of Clinical Endocrinology and Metabolism , Polycystic Ovary Syndrome (Pcos), Polycystic Ovary Syndrome, Infertility, Diagnosis, Metabolic, Metabolism, Women's Health

Women Dissatisfied with Long Process to Diagnose Polycystic Ovary Syndrome

A large international survey of women with a common condition called polycystic ovary syndrome (PCOS), which is characterized by reproductive and metabolic problems, found nearly two in three were dissatisfied with the length of time they waited and the number of healthcare professionals they had to see before they received a diagnosis, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Science

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Reproductive Biology, Epigenetics

Fertilized Egg Cells Trigger and Monitor Loss of Sperm’s Epigenetic Memory

Scientists from the Institute of Molecular Biotechnology (IMBA) in Vienna, Austria, have discovered how an embryo’s genomic integrity is safeguarded during the first 24 h after fertilization. Insights into this mechanism have implications for improving in vitro fertilization.

Medicine

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Daniel Thorek, Prostate, Cancer, Imaging, PSA, 11b6, Receptor

New Imaging Method Can Detect, Monitor and Guide Treatment For, Prostate Cancer

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An international group of researchers report success in mice of a method of using positron emission tomography (PET) scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer.

Medicine

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Physiology, Kidney Damage, Renal Function, Estrogen, Estrogen Based Therapy, Hormone Therapy, Menopause

Long-Term Use of Postmenopausal Estrogen Treatment May Impair Kidney Function

Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function.

Medicine

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Cancer, Cancer Research, Immunotherapy, Ovarian Cancer, Keytruda, pembrolizumab, Avastin, gut flora, Chemotherapy

New Ovarian Cancer Immunotherapy Study Poses Question: Can Microbiome Influence Treatment Response?

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A new clinical study underway at Roswell Park Cancer Institute is the first to test the combination of the immunotherapy pembrolizumab with two other drugs as treatment for recurrent epithelial ovarian cancer, and is also the first ovarian cancer clinical trial to incorporate analysis of patients’ microbiomes

Medicine

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Breastfeeding, Womens Health, Maternal And Child Health, disparities in healthcare, Minority Health, Access To Care

Study Shows Alarming Disparities in Health Outcomes Could Be Prevented by Breastfeeding

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Lack of paid leave and outdated maternity care are barriers to breastfeeding that disproportionately impact families of color. This is the first study to show how these disparities translate into differences in health outcomes.

Medicine

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donor egg, IVF, Miracle, Thanksgiving, Hodgkin Lymphoma, Oncofertility, Pregnacy, Infertility, patient stories

A Miracle for the Millers

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When Manda Miller called her parents to tell them she was pregnant, she knew it would be unexpected. But, starting a family was more than just a life detail on which Manda and Douglas Miller had been mum – Manda was a two-time survivor of Hodgkin’s Lymphoma. The aggressive treatment saved her life, but had taken her chance for children.

Medicine

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University of Pennsylvania School of Nursing, Penn Nursing Science, Penn Nursing, Anne Teitelman, HIV, HIVAIDS, H, PREP

Penn Nursing and New York Blood Center Receive NIMH Grant to Create HIV Prevention Program for Women

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The University of Pennsylvania School of Nursing and the New York Blood Center, in partnership with local community consulting groups, have received a $769,578 grant from the National Institute of Mental Health to embark on designing an awareness program on the usage of the daily oral medication Pre-Exposure Prophylaxis (PrEP).

Medicine

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Pregnancy and Childbirth, Longevity, Aging, Gerontology, advanced maternal age, OB GYN

Older First-Time Mothers Are Also More Likely to Live Longer

The average age of a woman giving birth for the first time has risen dramatically in the United States over the past 40 years, driven by factors like education or career. A new study by researchers at University of California San Diego School of Medicine found that women choosing to become first-time mothers later in life may increase their chances of living into their 90s.

Medicine

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Endocrine Society, Journal of Clinical Endocrinology and Metabolism , Bone Health, Menopausal Hormone Therapy, Menopause, Osteoporosis, Bone Structure, Bone Mass

Menopausal Hormone Therapy Improves Bone Health

Women who undergo hormone therapy for menopausal symptoms such as hot flashes can not only increase bone mass, but also can improve bone structure, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Medicine

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Eating Disorder, Women, Holiday Advice, Menstrual Cycle, Bulimia Nervosa, binge eating disorder

Season's Eatings - Do holiday temptations trigger eating disorders?

‘Tis the season of an abundance of food and drink. While celebrating should be joyful, for some women it can trigger eating disorder symptoms. Michigan State University Foundation Professor Kelly Klump has found that holiday temptations can add another layer of stress to an already complicated biological process. It is well known women undergo monthly hormonal changes in estrogen and progesterone due to the menstrual cycle.

Medicine

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Rafael Guerrero-Preston, Cervical Cancer, Cancer, test, HPV, Human Papilloma Virus, Urine

Johns Hopkins Scientists Advance a Novel Urine Test to Predict High-Risk Cervical Cancer

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Johns Hopkins Medicine specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue.

Medicine

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Breast Cancer Treatment, Breast Cancer, Breast Cancer Advances, Chemotherapy, Side Effects, Cancer

Drug Combination Therapy for Estrogen-Receptor–Positive Breast Cancer Passes Critical Step for Worldwide Approval

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• Breakthrough drug palbociclib (brand name IBRANCE) targets a key family of proteins to prevent cell growth in cancer • New UCLA-led study treated women with estrogen receptor positive (ER+), HER2-negative (HER2-) advanced breast cancer with a combination of palbociclib and standard anti-estrogen therapy letrozole • Study results found the drug combo increased progression-free survival from 14.5 months to over 25 months, compared to letrozole alone • The treatment was also found to be very well tolerated without the side effects of traditional chemotherapy, which can include infection, nausea and significant hair loss

Medicine

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Overweight, Overweight Adults, Obesity, Contraception, Birth Control, Weight Gain

Fear of Gaining Weight May Influence Contraception Choices

Concerns about weight gain may be driving contraception choices, according to Penn State College of Medicine researchers.

Medicine

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Pregnancy, Pregnancy Complications, Gestational Diabetes, Diabetes, Obesity, Body Mass Index, Weight, Winter

Winter Conception Increases Mothers' Diabetes Risk

Research led by the University of Adelaide has found that women whose babies are conceived in winter are more likely to develop gestational diabetes during pregnancy, increasing a range of risk factors for both child and mother.

Medicine

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Pregnancy, gut microbiome, Anxiety, Learning, Maternal Stress

Stress-Induced Changes in Maternal Gut Could Negatively Impact Offspring for Life

Prenatal exposure to a mother’s stress contributes to anxiety and cognitive problems that persist into adulthood, a phenomenon that could be explained by lasting – and potentially damaging – changes in the microbiome, according to new research in mice.







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