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Stem Cells

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Medicine

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Osteolectin, Bone Marrow, Stem Cell, bone cells, Ut Southwestern

CRI Scientists Discover New Bone-Forming Growth Factor That Reverses Osteoporosis in Mice

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A team of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) discovered a new bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has implications for regenerative medicine.

Medicine

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Mount Sinai, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Stem Cell, stem cell memory

Stem Cell Memories May Hold Answer to Their Reproduction, Mount Sinai Study Finds

Blood-forming stem cells are able to count and store memories of the number of times that they divide, findings which could have major implications for disease research, scientists at the Icahn School of Medicine at Mount Sinai have found.

Science

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How to Make a Motor Neuron

A team of scientists has uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons.

Medicine

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Leukemia, Acute Myeloid Leukemia (AML), Stem Cells, Gene signature, princess margaret cancer centre, University Health Network

Stem Cell-Based Test Predicts Leukemia Patients’ Response to Therapy to Help Tailor Treatment

Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.

Science

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TET Proteins Drive Early Neurogenesis

The fate of stem cells is determined by series of choices that sequentially narrow their available options until stem cells’ offspring have found their station and purpose in the body. Their decisions are guided in part by TET proteins rewriting the epigenome, the regulatory layer of chemical flags that adorn the genome and influence gene activity, report researchers at La Jolla Institute for Allergy and Immunology and UC San Diego.

Medicine

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cardiac stem cell research, Pulmonary Arterial Hypertension, Heart Institute, cardiosphere-derived cells , CDCs, Eduardo Marban

Cedars-Sinai Medical Center to Expand Clinical Safety and Effectiveness Evaluation of Cardiac Cell Therapy After Winning $7.3 Million California Institute for Regenerative Medicine Grant

Researchers from the Cedars-Sinai Heart Institute and the Cedars-Sinai Department of Medicine are expanding their ongoing evaluation of a novel cell-based therapeutic candidate into the area of pulmonary arterial hypertension (PAH). This work will be supported by a recently-awarded $7.3 million grant from the California Institute for Regenerative Medicine.

Medicine

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Immunotherapy, Acute Myeloid Leukemia, Dr. Aude Chapuis, Fred Hutchinson Cancer Research Center, Fred Hutch, Bone Marrow Transplant

Immunotherapy Shows Promise in Preventing Leukemia Relapse

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Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. Of the 12 AML patients who received this experimental T-cell therapy after a transplant put their disease in remission, all are still in remission after a median follow-up of more than two years.

Medicine

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Stem Cells, Cells, Ips Cells

Designer Switches of Cell Fate Could Streamline Stem Cell Biology

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Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods.

Medicine

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2016 World Stem Cell Summit, Mayo Clinic Center for Regenerative Medicine

Mayo Clinic Center for Regenerative Medicine to Co-Host World Stem Cell Summit 2016 Dec. 6-9

The Mayo Clinic Center for Regenerative Medicine is a co-sponsor of the 2016 World Stem Cell Summit. More than 1,200 attendees are expected at the 12th annual event in West Palm Beach, Florida.

Medicine

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abramson cancer center, C Diff, C Difficile, Vancomycin, ASH Conference

Preventative Antibiotics Could Prevent C. Diff Among Stem Cell Transplant Patients, Penn Study Finds

It may be possible to safely prevent one of the most common – and costly to treat – infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania. The researchers will present their findings at this week’s 58th Annual American Society of Hematology Meeting and Exposition in San Diego.

Medicine

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ophthalmology research, Stem Cell, Retinitis Pigmentosa, Retinal Diseases, Regenerative Medicine, Clinical Trials, California Institute For Regenerative Medicine, Rare Diseases

jCyte Completes Enrollment for Phase I/IIa Safety Trial

Regenerative medicine company jCyte has completed enrollment in a phase I/IIa trial studying the safety of its stem cell therapy for retinitis pigmentosa. Early results are promising.

Science

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Stem Cells, pluripotent stem cells, Intestines, enteric nervous system, Nature Medicine, Gastroinestinal, Cincinnati Children's Hospital Medical Center, National Institutes of Health, Stomach, regenerative therapy, personalized medicine, press release, Pediatrics, Hirschsprung disease, Hirschsprung

Scientists Tissue Engineer Human Intestines and Functioning Nerves

Scientists report in Nature Medicine using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder called Hirschsprung’s disease.

Science

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World Stem Cell Summit, RedMed Capital Conference, Research, Cell Therapy, Center for Collaborative Research, Nova Southeastern University, Immunotherapy

NSU Researchers to Present at World Stem Cell Summit

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The World Stem Cell Summit & RegMed Capital Conference has invited five faculty members from the Nova Southeastern University (NSU) Cell Therapy Institute to present on their research related to advancing new approaches to cancer immunotherapy and regenerative medicine at the organization’s 12th annual meeting.

Medicine

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Vascular, Cardiovascular, Heart, Transplants, Stem Cells

Morgridge–UW Project Investigates Tissue-Engineered Arteries for Transplant

The prospect of creating artery “banks” available for cardiovascular surgery, bypassing the need to harvest vessels from the patient, could transform treatment of many common heart and vascular ailments. But it’s a big leap from concept to reality.

Medicine

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Breast Cancer, Texas A&M College of Medicine, Thomas J. Bartosh, Stem Cells

A Possible Explanation for Recurring Breast Cancer

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In October, we mourned those who died of breast cancer and celebrated all of the women (and men) who have survived. What many of those survivors worry about, though, is that their breast cancer may come back. It has puzzled scientists and health care providers that cancer can suddenly reappear, often with a vengeance, months or years after treatment is over.

Medicine

Science

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organioids, Stem Cells, Respiratory Diseases

Lab-Grown Mini Lungs Successfully Transplanted Into Mice

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Scientists can now grow 3-D models of lungs from stem cells, creating new ways to study respiratory diseases.

Science

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Biofuel, algorithim, Stem Cell Research

Changing Cell Behavior Could Boost Biofuels, Medicine

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A computer scientist at Washington University in St. Louis has developed a way to coax cells to do natural things under unnatural circumstances, which could be useful for stem cell research, gene therapy and biofuel production.Michael Brent, the Henry Edwin Sever Professor of Engineering in the School of Engineering & Applied Science, has designed an algorithm, called NetSurgeon, that recommends genes to surgically remove from a cell’s genome to force it to perform a normal activity in a different environment or circumstance.

Medicine

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McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Stem Cells, Charles S. Cox Jr, Traumatic Brain Injury, TBI, autologous stem cells, white brain matter, Inflammation, Department Of Defense, National Institutes of Health

UTHealth Research: Stem Cell Therapy Appears to Have TBI Treatment Effect

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Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient’s own stem cells showed that the therapy appears to dampen the body’s neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

Medicine

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Burns, Biomedical Engineering, Stem Cell, skin grafts

A Skin Graft for Bad Burns

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To get a head start on healing burn wounds, biomedical engineers at Michigan Technological University turn to the body's natural network. They combine engineered stem cell sheets with split thickness skin grafts to do so.

Medicine

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ALS, Amyothrophic Lateral Sclerosis, Regenerative Medicine Institute, Baloh, Svendsen, Lou Gehrig disease, California Institute For Regenerative Medicine, Cirm

Cedars-Sinai Receives Approval to Test Novel Combined Stem Cell and Gene Therapy for ALS Patients

Cedars-Sinai regenerative medicine investigators have received approval from the U.S. Food and Drug Administration to test a combination stem cell-gene therapy they developed to stall the progression of amyotrophic lateral sclerosis. The approval allows 18 ALS patients to receive a new investigational drug in a few months when the study begins.







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