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Medicine

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Alzheimber's Disease, Dementia, Amyloid Beta, Pet Imaging, Memory Disorders, Prevention

Focus on Alzheimer’s Disease Shifts to Prevention

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UAB physicians say prevention, not cure, may be the key to coping with the rising incidence of Alzheimer's disease. New imaging techniques, coupled with a better understanding of the disease, provide new hope.

Medicine

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GW School of Medicine and Health Sciences, Cystic Fibrosis, Thymosin, Thymosin Alpha 1, University of Perugia, University of Rome, Biochemistry, Molecular Medicine, Genetics, Pediatrics, CF, respiratory conditions

Research Uncovers Potential New Treatment to Treat and Stop Progression of Cystic Fibrosis

Researchers published in Nature Medicine from the George Washington University, the University of Perugia, and the University of Rome have discovered a potential new drug to treat and stop the progression of cystic fibrosis. Thymosin α1 is a novel therapeutic single molecule-based therapy that not only corrects genetic and tissue defects, but also significantly reduces inflammation seen in cystic fibrosis patients.

Medicine

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Immunotherapy, Melanoma, Immune Response

Matching Pre-Treatment Tumor Size to Strength of Immune Response Allows Tailoring of Melanoma Drug Regimen

A new study published in Nature provides clues that could enhance physicians’ ability to pinpoint, in real-time, which patients are not responding to therapy – and intervene with additional drugs to boost the chances of shrinking tumors.

Medicine

Life

Social and Behavioral Sciences

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long-term effects of antibiotics, early-life antibiotic exposure, Penicillin

Low-Dose Penicillin in Early Life Induces Long-Term Changes in Behaviour

The researchers report that low-dose penicillin taken late in pregnancy and in early life of mice offspring, changes behaviour and the balance of microbes in the gut. While these studies have been performed in mice, they point to popular increasing concerns about the long-term effects of antibiotics.

Medicine

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ENDO 2017, Endocrine Society, Menopausal Hormone Therapy, Menopause, Bioidentical Hormones, Compounding, Hot Flash, Hot Flashes, Phase 3 clinical trial

New Natural Estrogen-Progesterone Capsule Reduces Postmenopausal Hot Flashes

A natural, or bioidentical, combined estradiol-progesterone capsule (TX-001HR) significantly decreases the frequency and severity of moderate to severe hot flashes in postmenopausal women, the Replenish study finds. Results of this phase 3, randomized, placebo-controlled, multicenter trial will be presented Monday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.

Medicine

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Hutfless, Gallbladder, Pancreatitis, cholecystectomy

Gallbladder Removal Is Common. But Is It Necessary?

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Johns Hopkins researchers say that the findings they published in the current edition of The American Journal of Gastroenterology could have important implications for the field of personalized medicine.

Medicine

Science

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Guided drug delivery, Nanocapsules, Microcapsules, Nanotechnology, Cancer, Solid Tumors, Metastatic Cancers, theranostic, Polymer Chemistry, Biomedical Science, Ultrasound, Contrast Agents, Tannic Acid, Poly(N-vinylpyrrolidone)

UAB Creates Triple-Threat Cancer-Fighting Polymer Capsules for Guided Drug Delivery

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Chemists have designed triple-threat cancer-fighting polymer capsules for guided drug delivery. They combine three traits: good imaging contrast with low-power ultrasound, stable packaging of the cancer drug doxorubicin, and ability to trigger drug release with low- or higher-power ultrasound.

Medicine

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AACR, Cancer, Research, Immunotherapy, Genomics, Proteomics, Cancer Moonshot, Sarcoma, CAR-T, CAR-T-cell, T-Cell

Fred Hutch Scientists to Cover Advances in Immunotherapy, Proteomics at AACR

Scientists from the Fred Hutchinson Cancer Research Center in Seattle are scheduled to present and discuss the latest developments in immunotherapy and proteomics at the American Association for Cancer Research Annual Meeting, Research Propelling Cancer Prevention and Cures, on April 1-5. What follows is a selection of the more than 30 Hutch presentations at the AACR gathering

Medicine

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Colon Cancer Research, Colon Cancer, Cancer Biomarkers

New Colon Cancer Biomarkers May Guide Development of Personalized Treatment

Researchers at Baylor Scott & White Research Institute identified a new genetic biomarker for colon cancer that may lead to development of more targeted treatment of the disease

Medicine

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Cancer, Lung Cancer, Sbrt, Stereotactic Body Radiation Therapy, non-small cell lung cancer, Nsclc, Radiotherapy, Radiation Therapy, Cancer Research, Multidisciplinary Thoracic Cancers Symposium

Updated Data on SBRT Radiation for NSCLC Lung Cancer Confirm Benefits of ‘One and Done’ Approach

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Collaborative study with Cleveland Clinic & SUNY Upstate Medical University shows that single high-dose SBRT treatment is as effective as three doses in patients with non-small cell lung cancer







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