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Medicine

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Society Of Toxicology, Toxicology, toxicologist, Annual Meeting, ToxExpo, data science, Precision Medicine, Epigenetic, Food Safety, Arsenic, Pesticide, Alternative Test Methods, Public Health, In Vitro, Organs-on-a-chip, Carcinogenesis, Air Pollution

Latest Research on Data Science, Precision Medicine, Epigenetics, Food Safety, Arsenic, Pesticides, Alternative Test Methods, and More Featured at SOT 56th Annual Meeting and ToxExpo

The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.

Medicine

Science

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Penn Computational Geneticist Receives Presidential Early Career Award for Scientists and Engineers

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Benjamin F. Voight, PhD, an assistant professor of Systems Pharmacology and Translational Therapeutics and of Genetics in the Perelman School of Medicine at the University of Pennsylvania, has received the Presidential Early Career Award for Scientists and Engineers.

Medicine

Science

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LSD, Pharmacology, Serotonin receptors, Acid, Psychedelic Drug Effects

This Is LSD Attached to a Brain Cell Serotonin Receptor

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UNC School of Medicine researchers crystalized the structure of LSD attached to a human serotonin receptor of a brain cell, and they may have discovered why an “acid trip” lasts so long.

Medicine

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laboratory technology, cell reprogramming, Precision Medicine, Cancer Drug, Cells

Scientists Describe Lab Technique with Potential to Change Medicine and Research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

Medicine

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pulmospheres, Pulmonary, IPF, Idiopathic Pulmonary Fibrosis, Precision Medicine

Precision Medicine: UAB Study Creates ‘Mini-Lung’ to Study Effect of Pulmonary Fibrosis Drugs

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Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from UAB presented today in JCI Insight.

Medicine

Business

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Wall Street, Infectious Disease, Stock Market, Pharmaceutical

Dangerous Infectious Diseases: Bad News for Main Street, Good News for Wall Street?

While infectious diseases may be dangerous for the general public, they are good news for stock market investors and traders, says a new study from the University of Portsmouth.

Medicine

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Buprenorphine, mat, Opioid Use Disorder, Telepsychiatry, Retention

Good Outcomes with 'Telepsychiatry' in Medical Treatment of Opioid Use Disorder

For people with opioid use disorder receiving medication treatment with buprenorphine, a telepsychiatry approach—using videoconferencing as an alternative to in-person group sessions—provides similar clinical outcomes, reports a study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). The journal is published by Wolters Kluwer.

Medicine

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Breast Cancer, Ovarian Cancer, Prostate Cancer, olaparib, PARP inhibitors, Metabolism, Lung Cancer

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

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Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study “Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells,” which has been published in The Journal of Cell Biology, suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

Medicine

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pediatric endocrinology, Growth Hormone Deficiency, growth hormone treatment, IGF-I deficiency, Idiopathic Short Stature, ISS, Children's Hospital Of Philadelphia, Medical Ethics

When Should Doctors Treat Short Children and Teens with Growth Hormone?

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When is it appropriate to treat short children with growth hormone? The answer is not always clear-cut, as many parents and physicians weigh social, medical and ethical concerns. Experts in pediatric endocrinology have issued a new set of guidelines for managing children and teens who have growth failure.

Medicine

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Cancer, Metformin, Diabetes Drug, Head And Neck Cancer, Pilot Clinical Trial, Medical Oncology

Diabetes Drug Takes Aim at Cancer’s Fuel Source

To understand how metformin changes the biology of cancer cells, researchers at the Sidney Kimmel Cancer Center at Thomas Jefferson University tested tumor cells before and after metformin treatment in non-diabetic cancer patients. The pilot clinical trial results were published today in The Laryngoscope.

Medicine

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Antidepressant

Brain Scan Before Antidepressant Therapy May Predict Response

A functional MRI brain scan may help predict which patients will respond positively to antidepressant therapy, according to a new study published in the journal Brain.

Medicine

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Scripps Florida Team Awarded $1.8 Million Grant to Develop Drugs for Heart Disease and Rheumatoid Arthritis

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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidates for a number of diseases, including heart disease, rheumatoid arthritis and several neurodegenerative disorders.

Medicine

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Cancer, Statin, Cancer Treatment, p53 gene

KU Researchers Find Statins May Hold Keys to Future Cancer Treatment

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Researchers at The University of Kansas Cancer Center have found that high doses of drugs commonly used to fight high cholesterol can destroy a rogue protein produced by a damaged gene that is associated with nearly half of all human cancers

Medicine

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Nilotinib, Alzheimers disease, Clinical Trials, neurotherapeutics, Drug Discovery

Georgetown Clinical Trial of Nilotinib in Alzheimer’s Disease Begins

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A clinical trial to examine the effect of nilotinib on clinical outcomes and biomarkers in people with mild to moderate Alzheimer’s disease has opened at Georgetown University Medical Center.

Medicine

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Surgery, Anticoagulant, Anti Clotting Medication

Standard of Care Anti-Clotting Drugs May Be Unnecessary for Most Surgery Patients

As many as three out of four surgery patients could be receiving anti-clotting medications that they do not need, according to a study led by investigators at the University of Utah School of Medicine. The research, to be published in Annals of Surgery, challenges standard of care guidelines specifying that all general surgery patients receive anticoagulants.

Medicine

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Drug Discovery

Robert R. Meyer Foundation Gift Boosts Drug Discovery Efforts

The Robert R. Meyer Foundation is supporting Southern Research’s Drug Discovery program with a $500,000 gift that aims to accelerate efforts to find new treatments for unmet medical conditions and rare and neglected diseases.

Medicine

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Wayne State University, NIH, Tinnitus, Otolaryngology

Wayne State University Research Team Develops New Diagnostic Tool to Identify Tinnitus in Animals

A team of researchers from Wayne State University has developed a behavioral tool that may significantly aid in understanding the underlying mechanisms of tinnitus, ultimately leading to new drugs and treatment methods.

Medicine

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New TSRI Method Could Turbocharge Drug Discovery, Protein Research

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A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins.

Medicine

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Anesthesiology, Physician Supervision, Anesthesia Care

Access to Anesthesia Care Is Not Improved When States Eliminate Physician Supervision, Study Finds

Patient access to anesthesia care for seven common surgical procedures is not increased when states “opt-out” of the Medicare rule that requires anesthesia to be administered with physician supervision, reports a study published in the Online First edition of Anesthesiology.

Medicine

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protien, Drug Development, Disease Progression

Structure of Atypical Cancer Protein Paves Way for Drug Development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.







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