Feature Channels: Digestive Disorders

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Released: 10-Aug-2023 1:10 PM EDT
Gastrointestinal viruses all but disappeared during COVID—but surged back two years on
American Society for Microbiology (ASM)

Following the first stay-at-home orders issued in the U.S. to curb the spread of COVID-19, gastrointestinal viruses such as norovirus, rotavirus and adenovirus all but disappeared from California communities, and remained at very low levels for nearly 2 years.

Newswise: Johns Hopkins Researchers Develop Gut-Restricted Drug to Treat IBD
Released: 10-Aug-2023 9:05 AM EDT
Johns Hopkins Researchers Develop Gut-Restricted Drug to Treat IBD
Johns Hopkins Medicine

A new study of mice and lab-grown human colon “organoids” indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

3-Aug-2023 4:00 PM EDT
Long-Term Use of Certain Acid Reflux Drugs Linked to Higher Risk of Dementia
American Academy of Neurology (AAN)

People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. This study does not prove that acid reflux drugs cause dementia; it only shows an association.

Released: 9-Aug-2023 1:15 PM EDT
A gutsy move – new study challenges conventional wisdom about nerve cell origins of “the second brain”
Beth Israel Deaconess Medical Center

Researchers present a completely new paradigm describing a developmental pathway by which the enteric nervous system development continues after birth.

Released: 9-Aug-2023 10:20 AM EDT
Academic-private partnership aims to reduce toxic effects of deadly digestive bacteria
Virginia Tech

The bacterium commonly referred to as C. diff is sometimes called “C-difficult” because it is so hard to treat, said Mohamed Seleem, director of the Center for One Health Research. Seleem and Nectagen Inc. have received a nearly $275,000 grant from the National Institute of Allergy and Infectious Diseases to study whether synthetic proteins developed by Nectagen can reduce the toxicity of the digestive bacteria.

Newswise: NCCN Announces Research Funding for Biomarker-Directed Therapy in Metastatic Colorectal Cancer, in Collaboration with Fight CRC and Pfizer
Released: 9-Aug-2023 8:55 AM EDT
NCCN Announces Research Funding for Biomarker-Directed Therapy in Metastatic Colorectal Cancer, in Collaboration with Fight CRC and Pfizer
National Comprehensive Cancer Network® (NCCN®)

The National Comprehensive Cancer Network (NCCN) Oncology Research Program (ORP) today announced new grants awarded to improve quality initiatives focused on optimizing biomarker-directed therapy in metastatic colorectal cancer.

Released: 8-Aug-2023 3:05 PM EDT
Mind what you eat and drink. Food and Water Safety stories for media.
Newswise

The latest headlines from the Food and Water Safety channel on Newswise.

       

Not for public release

This news release is embargoed until 7-Aug-2023 5:00 PM EDT Released to reporters: 1-Aug-2023 2:00 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 7-Aug-2023 5:00 PM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 7-Aug-2023 10:35 AM EDT
RSNA Launches Abdominal Trauma Detection AI Challenge
Radiological Society of North America (RSNA)

The Radiological Society of North America (RSNA) has launched the “RSNA 2023 Abdominal Trauma Detection AI Challenge” to explore whether artificial intelligence (AI) can be used to aid in the detection and classification of traumatic abdominal injuries.

   
Newswise: Digital Therapeutics and Innovations in GI Highlighted in the August Issue of AJG
Released: 7-Aug-2023 9:00 AM EDT
Digital Therapeutics and Innovations in GI Highlighted in the August Issue of AJG
American College of Gastroenterology (ACG)

The August issue of The American Journal of Gastroenterology includes several articles on digital therapeutics and innovations in GI, encouraging adoption of emerging GI technologies to advance GI care.

Released: 4-Aug-2023 3:30 PM EDT
New deep-learning approach gets to the bottom of colonoscopy
Tsinghua University Press

Researchers have developed a pair of modules that gives a boost to the use of artificial neural networks to identify potentially cancerous growths in colonoscopy imagery, traditionally plagued by image noise resulting from the colonoscopy insertion and rotation process itself.

   
Newswise: How the Gut Signals to the Brain
27-Jul-2023 2:25 PM EDT
How the Gut Signals to the Brain
Harvard Medical School

In a first, scientists define five types of colon neurons specialized for sending different signals to the brain.

Released: 2-Aug-2023 12:00 PM EDT
MD Anderson Research Highlights for August 2, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel biomarker that may predict the aggressiveness of pancreatic cancer precursors, insights into the structure and function of a breast and ovarian cancer susceptibility gene, a new approach to overcoming treatment resistance in ovarian cancer, distinguishing features of young-onset rectal cancer, a biomarker and potential target for metastatic lung cancer, machine learning models to better predict outcomes of patients with mantle cell lymphoma (MCL), and a promising therapy for patients with relapsed/refractory MCL.

Released: 2-Aug-2023 10:40 AM EDT
New study shows that WATS3D increases diagnostic yield of dysplasia in Barrett's esophagus, regardless of segment length
CDx Diagnostics

CDx Diagnostics, Inc., developer of the WATS3D AI Platform for the detection and surveillance of Barrett's esophagus (BE) and dysplasia, reported positive data in a recently published study, Benefit of Adjunctive Wide Area Transepithelial Sampling with 3- Dimensional Computer-Assisted Analysis Plus Forceps Biopsy Based on Barrett's Esophagus Segment Length, in the American Society for Gastrointestinal Endoscopy (ASGE) journal GIE (Gastrointestinal Endoscopy).

Newswise: Mercy Medical Center Recognized in U.S. News & World Report’s “Best Hospitals 2023-2024” Edition
Released: 1-Aug-2023 10:15 AM EDT
Mercy Medical Center Recognized in U.S. News & World Report’s “Best Hospitals 2023-2024” Edition
Mercy Medical Center

Mercy Medical Center in Baltimore, Maryland, has been recognized by U.S. News & World Report’s “Best Hospitals” rankings for 2023-2024.

Released: 1-Aug-2023 10:10 AM EDT
Ochsner Medical Center Ranked #1 in Louisiana for the 12th Consecutive Year by U.S. News & World Report
Ochsner Health

Ochsner Medical Center - New Orleans (OMC), inclusive of Ochsner Medical Center- West Bank and Ochsner Baptist, has been named by U.S. News & World Report to its 2023-2024 Best Hospitals. Additionally, OMC is the #1 hospital in the New Orleans metro area.

Released: 1-Aug-2023 8:00 AM EDT
GI symptoms persist in older female colorectal cancer survivors
Ohio State University

More than 4 out of 5 older women survivors of colorectal cancer may be experiencing a range of gastrointestinal symptoms many years after being diagnosed and treated, a new study suggests.

Not for public release

This news release is embargoed until 31-Jul-2023 5:00 PM EDT Released to reporters: 25-Jul-2023 2:00 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 31-Jul-2023 5:00 PM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 31-Jul-2023 3:00 PM EDT
New study findings underscore the importance of timely newborn screenings in early care for cystic fibrosis
Ann and Robert H. Lurie Children's Hospital of Chicago

Newborn screening for cystic fibrosis (CF) was fully implemented in all 50 states in the U.S. by 2010, but delays in timeliness of evaluation for infants with positive newborn screen tests persist. Through evaluation of national patient registry data, Dr. Martiniano and her team determined that later initiation of CF care is associated with poorer long-term nutritional outcomes.

Newswise: Cedars-Sinai July Research Highlights
Released: 28-Jul-2023 11:50 AM EDT
Cedars-Sinai July Research Highlights
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

Released: 28-Jul-2023 11:30 AM EDT
Neonatal Stem Cells from the Heart Could Treat Crohn’s Disease
Ann and Robert H. Lurie Children's Hospital of Chicago

Research from Ann & Robert H. Lurie Children’s Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn’s disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

Newswise: Transcription Factors Contribute to Subtypes of Colorectal Cancers
Released: 27-Jul-2023 11:05 AM EDT
Transcription Factors Contribute to Subtypes of Colorectal Cancers
Johns Hopkins Medicine

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes’ on/off switches.

Newswise: Belly Fat Hinders Digestive Disease Medications
Released: 25-Jul-2023 1:50 PM EDT
Belly Fat Hinders Digestive Disease Medications
Cedars-Sinai

The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at Cedars-Sinai found that inflammatory bowel disease (IBD) patients with higher levels of intra-abdominal visceral adipose tissue– a distinctive type of fat inside the abdomen −had lower rates of remission when treated with certain anti-inflammatory medications.

Newswise: Most pancreatic cancer patients don’t get lifesaving surgery
Released: 24-Jul-2023 3:05 PM EDT
Most pancreatic cancer patients don’t get lifesaving surgery
UT Southwestern Medical Center

Only 22% of Texas patients with early-stage pancreatic cancer received standard-of-care surgery to remove their tumors, researchers at UT Southwestern Medical Center report in a new study. The findings, published in the Journal of Surgical Oncology, are a call to action to improve treatment in the Lone Star State for this deadly disease, the authors say.

17-Jul-2023 10:00 AM EDT
CHOP Researchers Reveal How NSAIDs Worsen C. difficile Infections
Children's Hospital of Philadelphia

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a new paper published in Science Advances, researchers at Children’s Hospital of Philadelphia (CHOP) have begun to answer that question, showing that NSAIDs disrupt the mitochondria of cells lining the colon, sensitizing them to damage by pathogenic toxins.

18-Jul-2023 4:00 PM EDT
Higher income communities are 5.7 times more likely to get CTC than lower-income communities
Harvey L. Neiman Health Policy Institute

A new Harvey L. Neiman Health Policy Institute study found that Medicare fee-for-service beneficiaries who reside in communities with annual per capita income of $100,000 or more are 5.7 times more likely to receive CT colonography (CTC) than their counterparts residing in communities with per capita income of less than $25,000. This American Journal of Roentgenology study was based on a nationally representative sample of Medicare fee-for-service beneficiaries who received 785,103 colorectal cancer screening tests between 2011 and 2020.

Released: 19-Jul-2023 7:00 AM EDT
Flu during Pregnancy May Lead to Changes in Offspring’s Immune Function
American Physiological Society (APS)

A new study in mice suggests that having a common form of the flu during pregnancy may affect the next generation by impairing immune function in the gut. The study is published ahead of print in the American Journal of Physiology-Gastrointestinal and Liver Physiology.

Newswise: Pancreatic Cancer Vaccine Plus Immunotherapy and Antibody Spark Immune System Response in Pancreatic Cancers
Released: 17-Jul-2023 10:00 AM EDT
Pancreatic Cancer Vaccine Plus Immunotherapy and Antibody Spark Immune System Response in Pancreatic Cancers
Johns Hopkins Medicine

Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research directed by Johns Hopkins investigators.

Newswise: Missing a Rare Cause of Hereditary Cancer
Released: 12-Jul-2023 8:25 AM EDT
Missing a Rare Cause of Hereditary Cancer
Cedars-Sinai

New research from Cedars-Sinai Cancer investigators could warrant reconsideration of current screening guidelines to include a poorly recognized cause of Lynch syndrome, the most common cause of hereditary colorectal and endometrial cancers.

Newswise: The structure of a protein bound to DNA reveals how the toxicity of the cholera bacterium is activated
Released: 11-Jul-2023 8:20 AM EDT
The structure of a protein bound to DNA reveals how the toxicity of the cholera bacterium is activated
Institute for Research in Biomedicine Barcelona

A team led by Dr. Miquel Coll at the Institute for Research in Biomedicine (IRB Barcelona) and the Institute of Molecular Biology of Barcelona (IBMB-CSIC), in collaboration with researchers led by Dr. Eric Krukonis at the University of Detroit Mercy in the USA, has revealed the atomic structure of the ToxR protein bound to the DNA of two promoters of the genes that cause the virulence of this bacterium.

   
Released: 10-Jul-2023 1:00 PM EDT
أظهرت جراحة طفيفة التوغل لتحديد مرحلة سرطان البنكرياس نتائج إيجابية في تحديد سير المرض، وذلك وفقًا لدراسة أجرتها مايو كلينك.
Mayo Clinic

أظهرت دراسة نُشرت في مجلة الكلية الأمريكية للجراحين أن إجراء جراحة بسيطة للمرضى الذين شُخصت إصابتهم حديثًا بمرض سرطان البنكرياس قد يساعد في تحديد مدى انتشار السرطان مبكرًا ومعرفة مرحلته. وأضاف الباحثون أنه يفضل أن تُجرى هذه الجراحة قبل أن يبدأ المريض العلاج الكيميائي.

Released: 10-Jul-2023 12:35 PM EDT
Estudo da Mayo Clinic descobre que o estadiamento precoce do câncer de pâncreas com cirurgia minimamente invasiva tem resultados positivos no prognóstico do paciente
Mayo Clinic

Um estudo publicado na revista Journal of the American College of Surgeons revela que executar um procedimento minimamente invasivo em pacientes diagnosticados recentemente com câncer de pâncreas ajuda a identificar mais cedo a extensão do câncer e determinar o seu estágio.

Released: 6-Jul-2023 2:05 PM EDT
La determinación temprana de la etapa del cáncer de páncreas con cirugía de invasión mínima muestra resultados positivos en el pronóstico del paciente, según estudio de Mayo Clinic
Mayo Clinic

Un estudio publicado en el Journal of the American College of Surgeons revela que realizar un procedimiento quirúrgico menor en pacientes con un diagnóstico reciente de cáncer de páncreas ayuda a identificar la diseminación temprana del cáncer y determinar la etapa del cáncer.

Newswise: Bowel Research UK chooses Symplectic Grant Tracker to power life-changing research
Released: 6-Jul-2023 12:00 PM EDT
Bowel Research UK chooses Symplectic Grant Tracker to power life-changing research
Digital Science and Research Solutions Ltd

Bowel Research UK has chosen Symplectic Grant Tracker from Digital Science’s suite of flagship products to advance its aims of funding life-changing research into bowel cancer and other bowel diseases.

   
Released: 5-Jul-2023 6:55 PM EDT
Thousands suffer from tabooed disease. New method makes it easier to identify the right treatment
University of Copenhagen, Faculty of Health and Medical Sciences

A new study provides new ways of diagnosing bile acid diarrhoea and identifying the most effective treatment for the individual patient.

Newswise: Pancreatic Cancer Risk Lower if Pancreatic Cysts Remain Stable for Five Years
Released: 29-Jun-2023 4:05 PM EDT
Pancreatic Cancer Risk Lower if Pancreatic Cysts Remain Stable for Five Years
Yale Cancer Center/Smilow Cancer Hospital

Low-risk branch duct intraductal papillary mucinous neoplasms (IPMN) are the most common precancerous form of mucinous pancreatic cysts and once identified require regular surveillance imaging. But consensus is still forming around how long that watchful period should last.

Released: 29-Jun-2023 12:55 PM EDT
Staging pancreatic cancer early with minimally invasive surgery shows positive results in patient prognosis, Mayo Clinic study finds
Mayo Clinic

A study published in the Journal of the American College of Surgeons reveals that performing a minor surgical procedure on patients newly diagnosed with pancreatic cancer helps to identify cancer spread early and determine the stage of cancer.

Newswise: UT Southwestern toxicologist offers tips to keep food safe during summer grilling season
Released: 29-Jun-2023 11:35 AM EDT
UT Southwestern toxicologist offers tips to keep food safe during summer grilling season
UT Southwestern Medical Center

The arrival of summer marks the return of a cherished activity: backyard grilling. A UT Southwestern Medical Center toxicologist offers some cautionary guidelines to help you and your guests avoid food poisoning.

Newswise: One-Two Punch: Novel Drug Pairing Could Beat Pancreatic Cancer
27-Jun-2023 8:00 AM EDT
One-Two Punch: Novel Drug Pairing Could Beat Pancreatic Cancer
University of California San Diego

UC San Diego researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial.

Released: 26-Jun-2023 11:05 AM EDT
FODMAP Diet is Focus of IAFNS July 12 Webinar for Nutritionists, Researchers
Institute for the Advancement of Food and Nutrition Sciences

Careful use of a FODMAP diet with fewer fermentable carbohydrates can help manage symptoms in people with digestive disorders while maintaining good nutrition.

Newswise: Unraveling the connections between the brain and gut
Released: 22-Jun-2023 4:05 PM EDT
Unraveling the connections between the brain and gut
Massachusetts Institute of Technology (MIT)

The brain and the digestive tract are in constant communication, relaying signals that help to control feeding and other behaviors. This extensive communication network also influences our mental state and has been implicated in many neurological disorders.

   
Newswise: Tumor mutation associated with drug-resistant liver cancer, UT Southwestern study finds
Released: 22-Jun-2023 11:05 AM EDT
Tumor mutation associated with drug-resistant liver cancer, UT Southwestern study finds
UT Southwestern Medical Center

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib. The finding, published in the journal Gastroenterology, may lead to alternative treatments for the most common form of liver cancer.

16-Jun-2023 8:00 AM EDT
Helping ‘good’ gut bacteria and clearing out the ‘bad’ — all in one treatment
American Chemical Society (ACS)

Probiotics could be used as an effective treatment strategy for certain intestinal diseases, such as Crohn’s disease. Researchers reporting in ACS Central Science have developed a microgel delivery system for probiotics that keeps “good” bacteria safe while actively clearing out “bad” ones.

   
Newswise: 1 in 6 parents say child reports tummy pain at least monthly but many haven’t consulted with a doctor
14-Jun-2023 7:05 AM EDT
1 in 6 parents say child reports tummy pain at least monthly but many haven’t consulted with a doctor
Michigan Medicine - University of Michigan

Tummy aches are common among kids, with one in six parents in a new national poll saying their child experiences them at least once a month.

Released: 16-Jun-2023 3:50 PM EDT
New insights on bacteria that causes food poisoning
Osaka Metropolitan University

Recently, Providencia spp. which have been detected in patients with gastroenteritis, and similar to enterohemorrhagic Escherichia coli. O157 and Salmonella spp., have been attracting attention as causative agents of food poisoning.

15-Jun-2023 2:20 PM EDT
Patients with refractory metastatic colorectal cancer experience survival benefits with fruquintinib
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer. Findings from the global FRESCO-2 trial, published today in The Lancet, were first presented at the European Society for Medical Oncology (ESMO) Congress 2022.

Newswise:Video Embedded a-spy-in-the-belly
VIDEO
Released: 15-Jun-2023 3:05 AM EDT
A "spy" in the belly
Empa, Swiss Federal Laboratories for Materials Science and Technology

To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers at Empa and ETH Zurich have developed a patch with a sensor function. The polymer patch warns before the occurence of dangerous leaks on sutures in the gastrointestinal tract take hold, while closes the areas on its own. A new material now enables a fast, easy and non-invasive leak diagnosis. The team recently published their findings in the journal Advanced Science.

   


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