Curated News: Cell (journal)

Filters close
Released: 27-Sep-2023 10:05 AM EDT
Strength Is in This Glass's DNA
Brookhaven National Laboratory

Scientists at the Columbia University, University of Connecticut, and the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory were able to fabricate a pure form of glass and coat specialized pieces of DNA with it to create a material that was not only stronger than steel, but incredibly lightweight.

19-Sep-2023 5:05 PM EDT
UCSF QBI, University College London, and Mount Sinai Identify Shared Molecular Mechanisms Across SARS-CoV-2 Variants that Allow Virus to Thrive Despite Vaccination
Mount Sinai Health System

In a study published online in CELL today, scientists at UCSF QBI, University College London and the Icahn School of Medicine at Mount Sinai reported breakthrough findings on convergent evolutionary mechanisms shared by COVID-19 variants, allowing them to overcome both adaptive and innate immune system barriers.

Newswise:Video Embedded fast-track-strain-engineering-for-speedy-biomanufacturing
VIDEO
Released: 19-Sep-2023 11:15 AM EDT
Fast-Track Strain Engineering for Speedy Biomanufacturing
Lawrence Berkeley National Laboratory

Berkeley Lab scientists are accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.

Newswise: Regenerative Medicine: How Scientists Manufacture Cells
Released: 19-Sep-2023 11:05 AM EDT
Regenerative Medicine: How Scientists Manufacture Cells
Cedars-Sinai

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

Released: 19-Sep-2023 8:05 AM EDT
Cholesterol and Inflammation Demonstrate Alzheimer’s Link
Alzheimer's Center at Temple University Lewis Katz School of Medicine

A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer’s disease. The new work was published online August 25 in the journal Cells.

Released: 15-Sep-2023 1:15 PM EDT
Scientists Take Next Big Step in Understanding Genetics of Schizophrenia
University of North Carolina School of Medicine

Scientists figuring out which of the 5,000-plus genetic variants associated with schizophrenia have an actual causal effect in the development of the condition. Some of genetic variants regulate or alter the expression of genes involved in the condition.

Newswise:Video Embedded a-short-walk-and-a-long-journey
VIDEO
Released: 14-Sep-2023 11:05 AM EDT
A Short Walk and a Long Journey
Cedars-Sinai

A few weeks from now, Lizbeth Sanchez will say goodbye to her job in a Smidt Heart Institute laboratory and walk about 200 steps to a Cedars-Sinai classroom, where she will begin working on her doctorate in biomedical and translational research.

Released: 12-Sep-2023 10:05 AM EDT
HIV: two autopsies reveal where the virus hides
Universite de Montreal

A research team shows for the first time that HIV reservoirs are concentrated in the spleen and lymph nodes, and that they can travel throughout the body.

Released: 8-Sep-2023 10:05 AM EDT
Penn Medicine Research Uncovers Brain-Blood Barrier's Role in Governing Ant Behavior
Perelman School of Medicine at the University of Pennsylvania

The blood-brain barrier (BBB) has been found to play a significant role in controlling behavior critical to how ant colonies function, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

   
Newswise: Investigators Devise Test to Identify Brain Tumors from Cerebrospinal Fluid
Released: 6-Sep-2023 10:05 AM EDT
Investigators Devise Test to Identify Brain Tumors from Cerebrospinal Fluid
Johns Hopkins Medicine

Researchers with the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine and four other institutions have developed a molecular test to identify the presence of brain tumors by measuring abnormal genetic material shed by tumors and circulating in cerebrospinal fluid (CSF). A description of the work was published Aug. 15 in the journal Cell Reports Medicine.

Released: 28-Aug-2023 8:10 AM EDT
Ketogenic diet and its effects on tumour growth and 'wasting syndrome'
National University of Singapore (NUS)

Professor Ashok Venkitaraman, Director of the Cancer Science Institute of Singapore at the National University of Singapore, together with Assistant Professor Tobias Janowitz, Principal Investigator at the Cold Spring Harbor Laboratory in New York, and an international group of researchers from the USA and UK, have discovered that ketogenic diets delay tumour growth but accelerate cachexia, a wasting syndrome, an unintended side effect that could cause death.

Newswise: Topography of the genome influences where cancer mutations thrive, study shows
Released: 24-Aug-2023 11:00 AM EDT
Topography of the genome influences where cancer mutations thrive, study shows
University of California San Diego

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

Released: 22-Aug-2023 11:55 PM EDT
New antibiotic from microbial ‘dark matter’ could be powerful weapon against superbugs
Utrecht University

A new powerful antibiotic, isolated from bacteria that could not be studied before, seems capable to combat harmful bacteria and even multi-resistant ‘superbugs’.

   
Newswise: Severe COVID-19 may lead to long-term innate immune system changes
Released: 21-Aug-2023 3:35 PM EDT
Severe COVID-19 may lead to long-term innate immune system changes
NIH, National Institute of Allergy and Infectious Diseases (NIAID)

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

Newswise: Intermittent Fasting Improves Alzheimer’s Pathology
Released: 21-Aug-2023 12:35 PM EDT
Intermittent Fasting Improves Alzheimer’s Pathology
University of California San Diego

New results from researchers at UC San Diego School of Medicine suggest that intermittent fasting could be an effective treatment approach for Alzheimer’s disease.

Released: 18-Aug-2023 12:10 PM EDT
Stanford Medicine-led research identifies gene ‘fingerprint’ for brain aging
Stanford Medicine

Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of the molecular changes that take place in the brain to cause it. Now, a study in mice has determined that the most pronounced changes occur in the white matter, a type of nervous system tissue that’s integral to transmitting signals across the brain.

Newswise: Beneficial bacteria sense gut mucus to stay in line
Released: 17-Aug-2023 5:00 AM EDT
Beneficial bacteria sense gut mucus to stay in line
University of Oregon

The findings point to possible mechanisms behind intestinal conditions like Crohn’s disease and ulcerative colitis, and also suggest avenues to develop more effective probiotics.

   
Released: 16-Aug-2023 12:15 PM EDT
MD Anderson Research Highlights for August 16, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

   
Newswise: Understanding Epigenetic Changes in Glial Cells May be Key to Combatting Brain Tumors
Released: 15-Aug-2023 2:05 PM EDT
Understanding Epigenetic Changes in Glial Cells May be Key to Combatting Brain Tumors
Stony Brook University

Gliomas are incurable brain tumors. Researchers are trying to unlock the mysteries of how they originate from normal cells, which may lead to better treatments.

Released: 15-Aug-2023 12:50 PM EDT
Weaker transcription factors are better when they work together
Rice University

Bioengineers can tailor the genomes of cells to create “cellular therapies” that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch on bioengineered genes without occasionally turning on some of the cell’s naturally occurring genes.

   
Released: 14-Aug-2023 4:05 PM EDT
Scientists reveal how proteins drive growth of multiple cancer types
Washington University in St. Louis

Led by Washington University School of Medicine in St. Louis and other institutions around the world, the Clinical Proteomic Tumor Analysis Consortium has completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can’t be assessed by genome sequencing alone. Understanding how proteins operate in cancer cells raises the prospect of new therapies.

Newswise: Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease
Released: 9-Aug-2023 4:05 PM EDT
Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease
University of California San Diego

Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.

Newswise: Oldest extant plant has adapted to extremes and is threatened by climate change
Released: 9-Aug-2023 3:35 PM EDT
Oldest extant plant has adapted to extremes and is threatened by climate change
University of Freiburg

The rare moss Takakia has adapted over millions of years to a life at high altitudes.

Newswise: A Single Gene and a Unique Layer of Regulation Opens the Door for Novel Plant-Fungi Interactions
Released: 9-Aug-2023 2:05 PM EDT
A Single Gene and a Unique Layer of Regulation Opens the Door for Novel Plant-Fungi Interactions
Department of Energy, Office of Science

Plants have a complex layer of regulation that allows beneficial fungi to colonize their roots while protecting them from harmful ones such as pathogens. Researchers recently identified the underlying plant signaling processes within this layer of regulation that permits a specific beneficial bacteria species to colonize the roots of switchgrass.

Newswise: Team discovers broken ‘brake' of cancer mutation machine
Released: 7-Aug-2023 11:45 AM EDT
Team discovers broken ‘brake' of cancer mutation machine
UT Southwestern Medical Center

Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical Center researchers discovered. The findings, published in Cancer Cell, could lead to new interventions that thwart this process in prostate and other cancer types, making them far easier to treat.

Newswise: Ovarian Cancer: New Biological Markers Found That May Predict Which Patients Won't Respond to Chemotherapy
31-Jul-2023 7:50 PM EDT
Ovarian Cancer: New Biological Markers Found That May Predict Which Patients Won't Respond to Chemotherapy
Mount Sinai Health System

Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that may predict a subset of ovarian cancer patients who are unlikely to respond to chemotherapy. The multicenter study, published online August 3 in Cell, reports on a pioneering analysis of chemo-refractoriness in high-grade serous ovarian cancer (HGSOC). The work also implicates possible therapeutic targets for these patients.

2-Aug-2023 6:05 PM EDT
Major Ovarian Cancer Discovery; Findings Published in Cell
University of Arkansas for Medical Sciences

The Birrer Laboratory at the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute helped discover a proteogenomic signature in ovarian cancer that may improve the way the disease is treated around the world. The discovery, which identifies a 64-protein-gene signature that can predict primary treatment resistance in patients with high grade ovarian cancer, was published Aug. 3 in the journal Cell.

Newswise: How the Gut Signals to the Brain
27-Jul-2023 2:25 PM EDT
How the Gut Signals to the Brain
Harvard Medical School

In a first, scientists define five types of colon neurons specialized for sending different signals to the brain.

Released: 2-Aug-2023 11:10 AM EDT
How the Tropical Red Swamp Crayfish Successfully Invaded the Cold Regions of Japan
Chiba University

The red swamp crayfish—found originally in tropical regions—has become a highly invasive species across the globe. Over the years, they have successfully colonized habitats much colder than their original habitats, but the factors determining their cold resistance have remained elusive. Recently, a group of researchers in Japan has discovered genes that may help the red swamp crayfish produce protective proteins and adapt to the cold.

Newswise: Deadly fungus beaten with new type of treatment
Released: 1-Aug-2023 1:35 PM EDT
Deadly fungus beaten with new type of treatment
RIKEN

Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats.

Released: 31-Jul-2023 6:00 AM EDT
Un estudio indica que las anomalías cromosómicas podrían dificultar el crecimiento de algunos tumores agresivos
Mayo Clinic

Las anomalías cromosómicas son un rasgo característico de las células cancerosas. Los defectos en el genoma derivados de la separación incorrecta de cromosomas (y el ADN que contienen) en cada división celular conllevan crecimiento tumoral y resistencia al tratamiento.

Released: 31-Jul-2023 5:00 AM EDT
تشير الدراسات إلى إن اضطرابات الكروموسومات قد تمنع تكون بعض الأورام العنيفة
Mayo Clinic

تشوهات الكروموسومات هي السمة المميزة للخلايا السرطانية. تؤدي عيوب الجينوم الناتجة عن الفصل الخاطئ للكروموسومات (والحمض النووي الموجود فيها) أثناء عملية انقسام الخلايا إلى تطور الأورام ومقاومة العلاج.

Released: 31-Jul-2023 5:00 AM EDT
Estudo sugere que erros cromossômicos podem impedir alguns tumores agressivos
Mayo Clinic

Erros cromossômicos são uma marca registrada das células cancerígenas. Defeitos no genoma decorrentes da separação incorreta dos cromossomos (e do DNA contido neles) em cada divisão celular promovem crescimento do tumor e resistência a terapias.

Newswise: Asymptomatic infections may underlie recent rise in whooping cough
Released: 26-Jul-2023 1:35 PM EDT
Asymptomatic infections may underlie recent rise in whooping cough
La Jolla Institute for Immunology

In a new study, scientists at La Jolla Institute for Immunology (LJI) compared the immune response of individuals who received older versus newer versions of the whooping cough vaccine. The unexpected findings may help explain the recent rise in whooping cough cases and point to potential targets for the next generation of vaccines.

   
Newswise: New algorithm may fuel vaccine development
Released: 25-Jul-2023 1:55 PM EDT
New algorithm may fuel vaccine development
La Jolla Institute for Immunology

Immune system researchers have designed a computational tool to boost pandemic preparedness. Scientists can use this new algorithm to compare data from vastly different experiments and better predict how individuals may respond to disease.

   
Released: 24-Jul-2023 5:30 PM EDT
Why we lose fat and muscle during infection
Salk Institute for Biological Studies

Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.

Released: 24-Jul-2023 1:00 PM EDT
Gene conferring novel function to seahorse brood pouch identified
Sophia University

A team of scientists have identified an ‘orphan’ gene—a gene with no identifiable homologous sequences in other species or lineages—in the seahorse Hippocampus abdominalis.

Newswise: GW Researchers Develop Model to Study Neglected Tropical Diseases
Released: 24-Jul-2023 11:35 AM EDT
GW Researchers Develop Model to Study Neglected Tropical Diseases
George Washington University

Researchers at the George Washington University, in collaboration with colleagues in France and Germany, have developed a model organism to study neglected tropical diseases from a genetically modified parasitic worm.

Newswise: Fly Toolkit Created for Investigating COVID-19 Infection Mechanisms
Released: 21-Jul-2023 7:05 PM EDT
Fly Toolkit Created for Investigating COVID-19 Infection Mechanisms
University of California San Diego

Researchers have created a resource for analyzing how viruses infect human cells. The fruit fly-based toolkit provides a shortcut for assessing SARS-CoV-2 genes and understanding how they interact with human proteins, offering researchers a resource for new COVID-related drug therapies.

Released: 21-Jul-2023 2:10 PM EDT
Bodybuilding Supplement May Help Stave off Alzheimer’s
RUSH

The secret to protecting your memory may be a staple of a bodybuilder’s diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer’s disease.

Released: 21-Jul-2023 11:55 AM EDT
Oldest known molecule surprises researchers. It could lead to new important treatments
University of Copenhagen, Faculty of Health and Medical Sciences

The human body consists of numerous trillions of cells, and 60 percent of the energy used within a cell is dedicated to a specific molecular machine. That machine is responsible for producing proteins, which are fundamental building blocks of the body.

   
Newswise: Engineering New Metabolic Pathways that Function Across Microbial Kingdoms
Released: 20-Jul-2023 4:30 PM EDT
Engineering New Metabolic Pathways that Function Across Microbial Kingdoms
Department of Energy, Office of Science

Microbes have enormous potential to produce metabolites with potential industrial applications. To do so, microbes use groups of genes called biosynthetic gene clusters (BGCs) that code for the sets of necessary enzymes. Scientists have computationally predicted the products of hundreds of thousands of BGCs, but have experimentally confirmed fewer than 2,000 of them. Researchers have now developed a computational and experimental strategy to redesign BGCs and determine the natural chemical products they create.

Newswise: UT Southwestern stem cell biologists develop embryo model
Released: 20-Jul-2023 2:30 PM EDT
UT Southwestern stem cell biologists develop embryo model
UT Southwestern Medical Center

UT Southwestern Medical Center biologists have developed a new stem cell-based embryo model for studying early human development, tissue formation, and differentiation, offering valuable contributions to the field of developmental biology and regenerative medicine.

Released: 19-Jul-2023 5:05 PM EDT
Study sheds light on where conscious experience resides in brain
University of California, Berkeley

More than a quarter of all stroke victims develop a bizarre disorder — they lose conscious awareness of half of all that their eyes perceive.

Released: 19-Jul-2023 12:00 PM EDT
MD Anderson Research Highlights for July 19, 2023
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 18-Jul-2023 11:45 AM EDT
A key function for tight junctions in embryo models
Gladstone Institutes

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these signaling molecules guide a single layer of embryonic stem cells to form three layers of distinct cell types that will later become different parts of the body.

   
Newswise: A new sensor shows brain cells making and then breaking contact
Released: 18-Jul-2023 11:10 AM EDT
A new sensor shows brain cells making and then breaking contact
Osaka University

Researchers from SANKEN (The Institute of Scientific and Industrial Research) and the Graduate School of Frontier Biosciences at Osaka University reported the development of a sensor to look at Pcdh interactions in live neurons, which brings us closer to understanding this mystery.

   
Newswise: Notre Dame researchers invent trap for capturing and comparing individual bacterial cells
Released: 12-Jul-2023 3:25 PM EDT
Notre Dame researchers invent trap for capturing and comparing individual bacterial cells
University of Notre Dame

Together, Notre Dame's Paul Bohn and Joshua Shrout are searching for new ways to observe microorganisms like P. aeruginosa, moving beyond the traditional process of observing cell cultures grown in a Petri dish.

   
Newswise: Researchers Uncover Signal Needed for Blood-Brain Barrier
Released: 12-Jul-2023 11:45 AM EDT
Researchers Uncover Signal Needed for Blood-Brain Barrier
Harvard Medical School

What makes the vital layer of protective cells around the brain and spinal cord — the blood-brain barrier — more or less permeable has been one of the more mystifying questions in neuroscience.



close
20.91871