Feature Channels: Kidney Disease

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30-Dec-2016 8:05 AM EST
Structure of Kidney Failure Patients’ Blood Clots May Increase Their Risk of Early Death
American Society of Nephrology (ASN)

• Hemodialysis patients tend to have denser blood clots than individuals without kidney disease. • Dense blood clots were linked to an increased risk of premature death from cardiovascular and other causes.

23-Dec-2016 11:00 AM EST
Racial Disparities Exist in Children’s Access to Kidney Transplantation
American Society of Nephrology (ASN)

• In a study of children with kidney failure who were followed for a median of 7.1 years, black children had a 36% higher risk of dying than white children. The increase risk was mostly attributed to differences in access to transplantation. • Hispanic children had lower risk of death than white children even though they had lower access to transplantation.

23-Dec-2016 11:00 AM EST
Breast and Cervical Cancer Screening Rates Are Low in Women with Advanced Kidney Disease
American Society of Nephrology (ASN)

• In a recent study, most women with advanced chronic kidney disease had not received breast or cervical cancer screening in recent years. • Older age, greater comorbidities, and lower income were associated with a lower rate of screening.

16-Dec-2016 9:00 AM EST
Prior Kidney Damage May Pose Risks for Pregnant Women and Their Babies
American Society of Nephrology (ASN)

• Women with a history of recovered acute kidney injury had an increased rate of preeclampsia and delivered infants earlier than women with a history of normal kidney function.

Released: 22-Dec-2016 4:05 PM EST
Post-Op Complications Measurements Differ, Mayo Clinic Study Finds
Mayo Clinic

PHOENIX – How do medical professionals determine whether or not a patient has experienced a post-operative complication? A team of Mayo Clinic physicians and researchers has published results of a three-year study examining mechanisms for measuring and reporting postoperative infection complications. The study analyzed patient admissions between 2012 and 2014 at the four teaching hospitals across Mayo Clinic’s campuses in Arizona, Florida and Minnesota. The results are published online in the Annals of Surgery.

Released: 22-Dec-2016 2:05 PM EST
Kidney Transplant Donor, Recipient Will Attempt Mount Kilimanjaro Climb Together in 2017
University of Alabama at Birmingham

In an effort to bring awareness to the power and benefits of living organ donation, Hasberry, Kuykendall and Kuykendall’s son, Cade, will attempt to climb Mount Kilimanjaro in Tanzania, East Africa, in June 2017.

Released: 21-Dec-2016 12:05 PM EST
You Are What You Exhale
American Technion Society

Using an array of nanoscale sensors, researchers have identified distinct “chemical signatures” in breath samples, for several diseases (including lung cancer, ovarian cancer, Crohn's disease, Parkinson's disease and multiple sclerosis).

Released: 21-Dec-2016 9:00 AM EST
From Transplant Lab Worker to Donor, Alabama Man Becomes Part of UAB’s World-Record Kidney Chain
University of Alabama at Birmingham

Divyank Saini is one of 17 UAB employees who interpret lab samples to determine whether living - and deceased -donor transplants are possible. But Saini wanted to do more, and he did, becoming a donor in the world’s longest kidney transplant chain.

Released: 20-Dec-2016 10:05 AM EST
NYU Lutheran Expands Kidney Disease Services Under New Dialysis Director
NYU Langone Hospital - Brooklyn

Elizabeth Hammer, MD, has been appointed director of the Sunset Park, Brooklyn, medical center's dialysis unit. Dr. Hammer, a highly trained nephrologist, will lead the unit's expansion and emphasize patient safety and quality.

Released: 16-Dec-2016 6:00 AM EST
Investigating Kidney Biomarkers to Track Lupus
Michigan Medicine - University of Michigan

To try to better understand how the disease begins and progresses, researchers at the University of Michigan investigated whether kidney biomarkers would signal lupus progression and signs of complications.

9-Dec-2016 9:00 AM EST
Dementia and Alzheimer’s Disease Are Serious Health Concerns for Older Kidney Transplant Recipients
American Society of Nephrology (ASN)

• Risks of dementia and Alzheimer’s disease are higher in older kidney transplant recipients than in older adults in the general population. • Among kidney transplant recipients, those who developed dementia or Alzheimer’s disease had higher rates of organ loss and patient death than those who did not develop these conditions.

Released: 15-Dec-2016 12:05 PM EST
A Diet of Fruits, Vegetables May Help Kidney Disease Patients
Texas A&M University

Sometimes treating a chronic disease can be as simple as adding fruits and vegetables to the diet, at least that’s what researchers at the Texas A&M College of Medicine have found.

13-Dec-2016 5:00 PM EST
UAB Performs Deep South’s First HIV-Positive Kidney Transplant From HIV-Positive Deceased Donor
University of Alabama at Birmingham

Mississippi man transplanted at UAB is only the eighth HIV-positive to HIV-positive transplant recipient in the United States since implementation of the HOPE Act.

12-Dec-2016 11:00 AM EST
'Bone Marrow-Derived Immature Myeloid Cells Are a Main Source of Circulating suPAR Contributing to Proteinuric Kidney Disease'
RUSH

A study embargoed until Monday, 12/12 shows that a protein biomarker for chronic kidney disease originates in the bone marrow. This discovery of where the suPAR protein originates is an important step towards earlier detection –and possible prevention – of a disease suffered by one in 10 adults, kills 48,000 people and costs Medicare $49 billion each year.

2-Dec-2016 9:00 AM EST
Study Furthers Research on Protein Involved in Kidney Disease
American Society of Nephrology (ASN)

• Investigators reveal that Apol1, a protein implicated in kidney disease, is produced mainly by the liver.

2-Dec-2016 9:00 AM EST
Healthy Diet May Help Kidney Disease Patients Live Longer
American Society of Nephrology (ASN)

• A healthy diet high in fruits, vegetables, fish, legumes, cereals, whole grains, and fiber, and low in red meat, salt, and refined sugars was linked with a reduced risk of early death in an analysis of 7 studies

Released: 7-Dec-2016 5:05 AM EST
"Pulling" Bacteria Out of Blood
Empa, Swiss Federal Laboratories for Materials Science and Technology

Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets. The initial laboratory tests at Empa in St. Gallen have been successful, and seem promising.

Released: 2-Dec-2016 9:05 AM EST
Alpha Blockers More Effective for Large Kidney Stones
Michigan Medicine - University of Michigan

For the two-thirds of kidney stone patients who need more than just extra hydration to pass their stones, physicians are eager to find non-surgical ways to help. Now, a new review of the medical literature suggests alpha blockers may be useful in some cases.

Released: 2-Dec-2016 3:00 AM EST
Kidney Disease Hospitalization and Mortality Rates Continue to Decline in the U.S.
Michigan Medicine - University of Michigan

According to an annual data report from the United States Renal Data System (USRDS), hospitalization and mortality rates for patients with chronic kidney disease continue to decline in the U.S.

23-Nov-2016 4:00 PM EST
Simple Walking Program Provides Physical and Mental Benefits to Dialysis Patients
American Society of Nephrology (ASN)

• A simple home-based walking program improved physical capacity and quality of life in patients undergoing long-term dialysis.

Released: 1-Dec-2016 11:05 AM EST
Cigarette Smoke Exposure Increases Scar Tissue in the Kidney and Heart, Study Finds
American Physiological Society (APS)

Smoking may lead to fibrosis in the heart and kidneys and can worsen existing kidney disease, according to a new study. The research team suggests that exposure to cigarette smoke negatively affects genetic messaging that controls tissue scarring.

Released: 29-Nov-2016 11:05 AM EST
Long-Term Use of Postmenopausal Estrogen Treatment May Impair Kidney Function
American Physiological Society (APS)

Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function.

Released: 21-Nov-2016 9:05 AM EST
Three Risk Factors Suggest a Reduction in Healthy Renal Function in Patients with Diabetes
University of Cincinnati (UC) Academic Health Center

Patients with diabetes and suffering from acute kidney injury (AKI), proteinuria and uncontrolled blood sugar experience a sharp reduction in the number of years they have healthy renal function before being forced onto dialysis, according to researchers at the University of Cincinnati (UC) College of Medicine.

14-Nov-2016 2:05 PM EST
Tighter Blood Pressure Control May Save More Than 100,000 Lives Each Year in the U.S.
American Society of Nephrology (ASN)

• New research estimates the projected lives that would be saved if patients at high risk of cardiovascular disease underwent intensive blood pressure lowering. • The findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

18-Nov-2016 4:00 PM EST
High-Impact Clinical Trials Yield Results That Could Improve Kidney Care
American Society of Nephrology (ASN)

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented at ASN Kidney Week 2016, November 15–20 at McCormick Place in Chicago, IL.

18-Nov-2016 4:00 PM EST
Eleanor D. Lederer Elected President of the American Society of Nephrology
American Society of Nephrology (ASN)

• The American Society of Nephrology (ASN), the world’s largest organization of kidney health professionals, has elected Eleanor D. Lederer, MD, FASN, as the next ASN President. • Dr. Lederer officially assumes her role as ASN President during the society’s annual meeting, ASN Kidney Week 2016, the largest gathering of kidney care specialists in the world, and will begin her term on January 1, 2017.

14-Nov-2016 1:05 PM EST
Short and Poor Quality Sleep May Have Negative Effects on Kidney Function
American Society of Nephrology (ASN)

• In a study of patients with chronic kidney disease, each additional hour of nighttime sleep was linked with a 19% lower risk of developing kidney failure. • There was also a significant association between sleep quality and kidney failure risk. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 1:05 PM EST
Coordination of Care Benefits Patients with Kidney Disease and Reduces Medical Costs
American Society of Nephrology (ASN)

• Multi-disciplinary care—or coordination of care among different clinicians and specialists—improves the health of patients with kidney disease and reduces costs compared with usual care. • Results from the study will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 2:05 PM EST
Scientists Get Closer to Developing Bioartificial Kidney
American Society of Nephrology (ASN)

• Researchers have developed a key component needed to create a bioartificial kidney. • The advance will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 1:05 PM EST
Simple Saliva Test May Help Clinicians Diagnose Kidney Disease
American Society of Nephrology (ASN)

• A dipstick test for salivary urea nitrogen was accurate for diagnosing kidney disease in adults in Malawi, Africa. • Results of the test also helped predict patients’ risk of early death. • The test will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 2:05 PM EST
Reflux and Ulcer Medications Linked to Kidney Stones and Chronic Kidney Disease
American Society of Nephrology (ASN)

• Individuals who took proton pump inhibitors or histamine receptor-2 blockers for heartburn, acid reflux, or ulcers had elevated risks of developing kidney stones. • In individuals without acute kidney injury, proton pump inhibitors were linked with a higher risk of developing chronic kidney disease or kidney failure compared with histamine receptor-2 blockers. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

Released: 18-Nov-2016 9:00 AM EST
ASN Foundation for Kidney Research Announces Campaign to Guarantee Research Funding
American Society of Nephrology (ASN)

The ASN Foundation for Kidney Research (ASN Foundation) is proud to announce the public launch of its Securing the Future Campaign during ASN Kidney Week 2016. This campaign coincides with the 50th anniversary of the American Society of Nephrology (ASN) and the 20th anniversary of the Career Development Grants Program.

Released: 18-Nov-2016 9:00 AM EST
The American Society of Nephrology Honors Leader in the Fight Against Kidney Disease
American Society of Nephrology (ASN)

• Amit X. Garg, MD, PhD will be presented with the ASN-AHA Young Investigator Award during ASN Kidney Week 2016, the world’s premier nephrology meeting where more than 13,000 kidney health professionals from around the world will gather in Chicago, IL from November 15–20.

14-Nov-2016 1:05 PM EST
Program May Help Increase Numbers of Live Kidney Donors
American Society of Nephrology (ASN)

• The Live Donor Champion program increased knowledge of live donation and comfort approaching others about live donation, and it boosted live donor referrals. • The program will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 1:05 PM EST
Method to Create Kidney Organoids From Patient Cells Provides Insights on Kidney Disease
American Society of Nephrology (ASN)

• Scientists have developed a method to coax human pluripotent stem cells to mature into cells that go on to form the functional units of the kidney. • The team has demonstrated how the method can be used to study human kidney diseases. • The research will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 1:05 PM EST
Smoking May Block Some of the Benefits of Kidney Disease Medications
American Society of Nephrology (ASN)

• In a study of patients with chronic kidney disease, nonsmokers and smokers who successfully quit had slower worsening of their kidney function than those who were unsuccessful at quitting. • Cigarette smoking partially negated the kidney-protective effects of patients’ medications. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 2:05 PM EST
Research Provides Insights on the Link Between Kidney Damage and Cognitive Impairment
American Society of Nephrology (ASN)

• Kidney damage was linked with worse performance on tests of global cognitive function, executive function, memory, and attention. • Kidney damage may also be linked with structural abnormalities in the brain. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

17-Nov-2016 5:30 PM EST
Wayne State and Henry Ford Present Findings on Reducing Hospital Visits for Patients with ESRD and CKD
Wayne State University Division of Research

On November 17, 2016, a Wayne State University doctoral student, Matthew Jasinski, will present results from his dissertation at the Annual Meeting of the American Society of Nephrology in Chicago. The study demonstrates the value of proactive identification of and family psychoeducation about cognitive impairment in patients with End State Renal Disease or Chronic Kidney Disease (ESRD/CKD). A team from Henry Ford Hospital led by Mark Ketterer, Ph.D., a clinical psychologist in the Department of Behavioral Health Services, collaborated with Jasinski, a Wayne State Department of Psychology graduate student, and Mark Lumley, Ph.D., professor of psychology at Wayne State, to conduct a clinical trial that sought to reduce the number of 30-day hospital readmissions by educating patients with ESRD and their family members about the patient’s health needs.

Released: 17-Nov-2016 5:05 PM EST
David Cooper, World Renowned Xenotransplantation Researcher, Joins UAB
University of Alabama at Birmingham

Cooper will join Joseph Tector as co-director of UAB’s Xenotransplantation Program with their research geared toward using genetically modified pigs to facilitate kidney transplants in humans.

11-Nov-2016 8:05 AM EST
Kidney Failure Patients’ Advance Directives Often Inadequately Address End-of-Life Decisions Related to Dialysis
American Society of Nephrology (ASN)

• In a recent analysis, approximately half of dialysis patients had advance directives, but only 3% specifically addressed dialysis management at the end of life. • Patients were far more likely to address other end-of-life interventions than dialysis in their advance directives.

11-Nov-2016 1:05 PM EST
Reducing Salt Intake May Help Protect Kidney Patients’ Heart and Kidney Health
American Society of Nephrology (ASN)

• In patients with chronic kidney disease, dietary sodium restriction reduced albuminuria (an indicator of kidney dysfunction) and blood pressure, whereas paricalcitol (a vitamin D receptor activator) in itself had no significant effect on these measures. • The combination of paricalcitol and a low sodium diet resulted in the lowest albuminuria levels in patients.

14-Nov-2016 1:05 PM EST
Telemedicine Program Provides Life-Saving Kidney Care to Patients in Rural Areas
American Society of Nephrology (ASN)

• A telemedicine program that partners a national dialysis provider with a rural hospital in Kentucky can surmount traditional barriers to deliver kidney care to rural hospitals. • The program will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

14-Nov-2016 2:30 PM EST
Study: Rheumatoid Arthritis Patients Who Smoke or Are Overweight See Less Symptom Improvement with Treatment
Hospital for Special Surgery

A study finds that smoking or being overweight makes it more difficult for patients with rheumatoid arthritis to achieve optimal control of inflammation and symptoms, despite standard of care treatment.

Released: 15-Nov-2016 2:05 PM EST
New Bioinformatic Analysis Reveals Role of Proteins in Diabetic Kidney Disease
UC San Diego Health

A new bioinformatic framework developed by researchers at University of California San Diego School of Medicine has identified key proteins significantly altered at the gene-expression level in biopsied tissue from patients with diabetic kidney disease, a result that may reveal new therapeutic targets.

Released: 14-Nov-2016 4:05 PM EST
Media Alert: American Society of Nephrology Kidney Week Press Briefing
American Society of Nephrology (ASN)

What: American Society of Nephrology Kidney Week Press Briefing When: Friday, November 18 at 9:45 a.m. CST Where: McCormick Place, Room W473 Embargoed until Saturday, November 19, at 10:30 CST (11:30 EST) Why: Briefing will feature presentations of High-Impact Clinical Trials. Dr. Pascale Lane and Dr. Gretchen Lehman Brandt will moderate and provide context and expert commentary on the science presented.

10-Nov-2016 11:05 AM EST
New Drug Beats Standard Therapy in Advanced Kidney Cancer
Dana-Farber Cancer Institute

An experimental kidney cancer drug outperformed the standard first-line therapy for patients with metastatic disease who are considered at risk for poorer than average outcomes, according to results of a randomized phase II clinical trial by researchers at Dana-Farber Cancer Institute.

Released: 14-Nov-2016 9:00 AM EST
Houston Methodist Researcher Recognized by AHA’s Circulation Research Editorial Board
Houston Methodist

Research published by a Houston Methodist team led by John Cooke, M.D., Ph.D., received high accolades at this year’s American Heart Association Scientific Sessions.

9-Nov-2016 9:00 AM EST
Allopurinol Does Not Increase Chronic Kidney Disease Risk in Gout Patients
American College of Rheumatology (ACR)

Allopurinol, a widely used treatment for lowering serum urate levels, does not appear to increase risk of kidney deterioration in gout patients with normal or near-normal kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington.

9-Nov-2016 9:00 AM EST
Urate-Lowering Therapy Helps Chronic Kidney Disease Patients Improve Organ Function
American College of Rheumatology (ACR)

Chronic kidney disease patients who take urate-lowering therapy and achieve target urate levels show improvement in kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington.

4-Nov-2016 9:00 AM EDT
Study Uncovers Link Between Constipation and Kidney Disease
American Society of Nephrology (ASN)

• Individuals with constipation had a 13% higher likelihood of developing chronic kidney disease and a 9% higher likelihood of developing kidney failure compared with individuals without constipation. • More severe constipation was linked with an incrementally higher risk for both chronic kidney disease and kidney failure.



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