Young children who take antibiotics may disrupt their gut’s microbial ecosystem and be more likely to develop prediabetes in adolescence, new research from Greece reports. The study results will be presented in a poster Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.
Use of a common nonprescription antimicrobial, triclocarban (TCC), during pregnancy and breast-feeding may alter the offspring’s composition of intestinal bacteria and other micro-organisms, called the gut microbiota, a new animal study finds. Presentation of the results will take place Friday at the Endocrine Society’s 98th annual meeting in Boston.
Many Danes are prescribed NSAIDs for the treatment of painful conditions, fever and inflammation. But the treatment also comes with side effects, including the risk of ulcers and increased blood pressure. A major new study now gathers all research in the area. This shows that arthritis medicine is particularly dangerous for heart patients, and also that older types of arthritis medicine, which have not previously been in focus, also appear to be dangerous for the heart.
A previous history of cancer doesn't necessarily preclude treatment with antibodies against tumor necrosis factor (anti-TNF) for patients with inflammatory bowel diseases (IBD), suggests a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer.
Children with autism have no unique pattern of abnormal results on endoscopy or other tests for gastrointestinal (GI) disorders, compared to non-autistic children with GI symptoms, reports a study in the Journal of Pediatric Gastroenterology and Nutrition (JPGN), official journal of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. The journal is published by Wolters Kluwer.
AIDP today released the following comments on a double-blind, randomized, placebo-controlled study conducted by researchers at the University of California Los Angeles (UCLA), published in the Frontiers of Physiology which shows that daily doses as low as 1g of PreticX®, a XOS (xylooligosaccharide), significantly modified gut microbiota, helping to grow more species of good gut bacteria and reduce bad bacteria in both healthy people, and those who are over-weight with unhealthy blood glucose levels.
Based on new evidence, the age of introduction of gluten into the infant diet—or the practice of introducing gluten during breast-feeding—does not reduce the risk of celiac disease in infants at risk, according to a Position Paper of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). The statement appears in the Journal of Pediatric Gastroenterology and Nutrition (JPGN), official journal of ESPGHAN and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, published by Wolters Kluwer.
Mount Sinai Researchers Led Long-Term Surveillance Study, First of its Kind, Showing Chromoendoscopy More Effective than Standard Colonoscopy in These Patients
New research from North Carolina State University and the University of Michigan finds that bile acids which are altered by bacteria normally living in the large intestine inhibit the growth of Clostridium difficile, or C. diff.
Microbiota regulate the ability of lung dendritic cells to generate immune responses.
A new meta-analysis has found that the beneficial effects of using psychological therapy to treat the symptoms of irritable bowel syndrome are not only short term but are also long lasting.
Wyss Institute's human gut-on-a-chip technology used to co-culture gut microbiome and human intestinal cells could lead to new therapies for inflammatory bowel diseases.
Genetic variation in patients with inflammatory bowel disease (IBD) appears to play a major role in determining how sick they will become and could provide a road map for more effective treatments.
A new study from researchers at Tufts University found that coconut oil controlled the overgrowth of a fungal pathogen called Candida albicans in mice. In humans, high levels of C. albicans in the gastrointestinal tract can lead to bloodstream infections, including invasive candidiasis. The research suggests that it might be possible to use dietary approaches as an alternative to antifungal drugs in order to decrease the risk of infections caused by C. albicans.
University of Oregon scientists have found that strength in numbers doesn't hold true for microbes in the intestines. A minority population of the right type might hold the key to regulating good health.
New research led by scientists at Beth Israel Deaconess Medical Center helps explain the role of an immunosuppressive pathway associated with irritable bowel disease, a condition that develops in genetically susceptible individuals when the body's immune system overreacts to intestinal tissue, luminal bacteria or both.
Right now, in any US hospital, about half of the patients have a prescription for an acid-reducing drug to reduce heartburn or prevent bleeding in their stomach and gut. But that well-intentioned drug may actually boost their risk of dying during their hospital stay – by opening them up to infections that pose more risk than bleeding would.
Training in meditation and other mindfulness-based techniques brings lasting improvements in mental health and quality of life for patients with inflammatory bowel diseases (IBD), according to a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer.
Advanced cancer patients given a drug designed to relieve constipation caused by pain killers lived longer with less tumor progression than those who did not receive or respond to the drug, researchers report at the American Society of Anesthesiologists. This is the first study in humans to associate opioid blockade with longer survival.
Each 80 minutes/day (assuming 16 awake hours/day) increase in sedentary duration was linked with a 20% increased likelihood of having chronic kidney disease in a recent study. Research that uncovered the association between sedentary behavior and kidney disease will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
Featured abstract authors and renowned experts in the field of gastroenterology offer clinical insight and real-world perspective in a series of video press briefings that highlight the key science presented this week at the American College of Gastroenterology's (ACG) 80th Annual Scientific Meeting in Honolulu. More than 4,000 gastroenterologists, physicians and other health care professionals from around the world will convene at the Hawaii Convention Center to review and present the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.
A study published in the New England Journal of Medicine found that vitamin D and calcium supplements do not reduce the risk of colorectal adenomas, which are benign tumors that can evolve into colorectal cancer.
One out of ten people suffer from irritable bowl syndrome, says Richard Benya, MD, gastroenterologist, Loyola University medical center. He offers tips on IBS.
Different treatments for Crohn's disease in children affects their gut microbes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients.
New research in the area of fecal microbiota transplantation (FMT) further advances understanding of the safety and effectiveness of FMT for Clostridium difficile, suggests gut microbiota changes may play a role in predicting treatment failure, and explores whether donor stool can impact an FMT recipient’s weight, are among the highlights of the American College of Gastroenterology's (ACG) 80th Annual Scientific Meeting, which will be held this week in Honolulu. More than 4,000 gastroenterologists, physicians and other health care professionals from around the world will convene at the Hawaii Convention Center to review and present the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.
In this presentation, Dr. Spiegel will address how information technology will transform gastroenterology. Dr. Chey will discuss the emerging role of diet as a treatment strategy for patients with GI conditions. In addition, the panelists take a look back at the AJG and a look ahead at the evolution of research related to food and the advances of technology. Panelists will be available for media questions in the press room immediately following the The American Journal of Gastroenterology Lecture.
A team of researchers has discovered that bacteria found in the gut may contribute to the body’s response to gluten, an important finding that could lead to new treatments for celiac disease. The findings, published today in The American Journal of Pathology, address a lingering question that has preoccupied scientists: why only a small amount – 2 to 5 per cent — of individuals who are genetically susceptible go on to develop the disease.
Working with gut stem cells from humans and mice, scientists from the Johns Hopkins Children's Center and the University of Pittsburgh have successfully grown healthy intestine atop a 3-D scaffold made of a substance used in surgical sutures.
Researchers at the UNC School of Medicine found that people with anorexia nervosa have very different microbial communities inside their guts compared to healthy individuals and that this bacterial imbalance is associated with some of the psychological symptoms related to the eating disorder.
Colorectal cancer will claim the lives of close to 50,000 Americans this year, according to the American Cancer Society. Screening is the most effective way to reduce the risk of dying from the disease, yet as a Penn Medicine physician argues in an editorial this week in the journal Gastroenterology, current recommendations to screen older people with a family history of colorectal cancer, specifically with colonoscopy every five years, is not justified for most patients. Chyke A. Doubeni, MD, MPH, chair of the department of Family Medicine and Community Health at the Perelman School of Medicine at the University of Pennsylvania, is the co-author of the editorial.
A study by scientists at Children’s Hospital Los Angeles has shown that tissue-engineered colon derived from human cells is able to develop the many specialized nerves required for function, mimicking the neuronal population found in native colon.
Investigators at Children’s Hospital Los Angeles have found that a common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation by inhibiting pathogenic T-cells.
The gut bacteria of infants who developed tolerance to cow’s milk after treatment with probiotic formula showed significant differences from those who remained allergic, according to a new study published September 22, 2015, in The ISME Journal by scientists from the University of Chicago, Argonne National Laboratory and the University of Naples Federico II, Italy.
Approximately 20 million Americans will experience some type of gastroesophageal reflux disease, or GERD, in their lives. In some cases, patients suffer resulting heart burn or acid regurgitation so severe that they require surgery to repair damage to their esophagus. A clinical trial at UC San Diego Health is using a new, FDA-approved device that reconstructs the esophagus through the mouth and requires no incisions.
A novel, one-step method to treat ulcerative colitis with an oral drug consisting of microparticles and natural herbal molecules that target the colon shows promise as an effective therapy, according to researchers from the Institute for Biomedical Sciences at Georgia State University and Southwest University in China.
Researchers analyzing the complicated genetic influences in inflammatory bowel disease have discovered new gene variants associated with an often-severe type of the disease that affects children under age five. The genes play key roles in immune function.
In the August issue of the Journal of Gastrointestinal Surgery, Mayo Clinic researchers provided a detailed comparison of patient outcomes associated with synchronous and sequential colorectal and liver resections in patients with stage IV colorectal cancer, identifying some benchmarks for surgical practice.
Researchers at the Johns Hopkins University School of Medicine, along with colleagues at Emory University and Cedars-Sinai, have published in the journal Gastroenterology the first major, in-depth analysis of genetic risk factors of inflammatory bowel disease in African-Americans.
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A protein found in dairy is discovered to be a prebiotic that holds promise for treating gastrointestinal conditions and obesity. This study is published ahead-of-print in the American Journal of Physiology—Gastrointestinal and Liver Physiology.
Scientists at the UNC School of Medicine and the UNC Lineberger Comprehensive Cancer Center found that a rare type of stem cell is immune to radiation damage thanks to high levels of a gene called Sox9.
A group of researchers at the University of Waterloo in Ontario, Canada has reached deep into the human gut, plucked out a couple enzymes produced by bacteria residing there and determined their biological activities and molecular structures -- details that should shed new light on how we digest many of the foods we eat.
The research explains the complex mechanisms of interaction and dynamics between the gut microbiota and its host. Data show that relatively minor changes in microbiota profiles or its metabolic activity induced by neonatal stress can have profound effects on host behaviour in adulthood.
Researchers at MIT’s Koch Institute for Integrative Cancer Research and Massachusetts General Hospital have created a polymer gel that could allow for the development of long-acting devices that reside in the stomach, including orally delivered capsules that can release drugs over a number of days, weeks, or potentially months following a single administration.
Other topics include ethnic disparities in pain treatment, colon cancer and IBD, halting Liver cancer, and more...
UCLA scientists have discovered a groundbreaking experimental therapy that has the ability to suppress the development of ulcerative colitis (UC), a disease which causes inflammation in the digestive tract and colon cancer. The treatment utilizes a chemical inhibitor able to block an RNA molecule (microRNA-214) involved in the transmission of genetic information.
Patients over 50 with ulcerative colitis (UC), a chronic disease of the colon, who undergo surgery to treat their condition live longer than those who are treated with medications, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. The results are published this week in Annals of Internal Medicine.
Children with inflammatory bowel disease (IBD) who are doing well on specific biological medications should not be switched to recently approved "biosimilar" products, concludes an expert consensus statement of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). The statement appears in the Journal of Pediatric Gastroenterology and Nutrition, the official journal of the European Society of Paediatric Gatroenterology, Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, published by Wolters Kluwer.
Other topics include the importance of nursing in medicine, more efficient drug development, studying the arts improves medical care, and more...
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