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Medicine

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ENDO 2017, Endocrine Society, Prostate Cancer, University of Tennessee Health Science Center, Prostate Cancer Treatment, Drug Development, Cancer, Endocrinology

New Molecules May Offer Treatment Option for Some Aggressive Prostate Cancers

Novel molecules called selective androgen receptor degraders (SARDs) may offer the next generation of treatment options for advanced prostate cancer, a new industry-sponsored study reports. The results of this research will be presented Saturday, April 1, at ENDO 2017, the 99th annual meeting of the Endocrine Society, in Orlando, Fla.

Medicine

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Bisphenol S (BPS), Breast Cancer, Bisphenol A (BPA), endocrine-disrupting chemicals, Endocrinology, Breast Cancer Cells, Estrogen, ENDO 2017, Endocrine Society

Exposure to BPA Substitute, BPS, Multiplies Breast Cancer Cells

Bisphenol S (BPS), a substitute for the chemical bisphenol A (BPA) in the plastic industry, shows the potential for increasing the aggressiveness of breast cancer through its behavior as an endocrine-disrupting chemical, a new study finds. The results, which tested BPS in human breast cancer cells, will be presented Saturday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.

Medicine

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obesity and cancer

New Study: Aggressive Breast Cancer Grows Faster in Obese Environment

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In an abstract that will be presented at a poster session to be held from 1 to 5 p.m. April 3 at the American Association for Cancer Research Annual Meeting 2017, UNC Lineberger Comprehensive Cancer Center researchers will report their preliminary findings that breast cancer cancer cells grew larger when they were transplanted into fatty, obese tissue.

Medicine

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UTI, Urinary Tract Infection , recurrent UTI, Gardnerella vaginalis

Vaginal Bacteria Can Trigger Recurrent UTIs, Study Shows

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Vaginal bacteria can trigger recurrent UTIs, according to a study in mice. The findings help explain why sex is associated with UTIs. When it gets in the bladder, the vaginal bacterium Gardnerella vaginalis triggers dormant E. coli from a prior infection to re-start multiplying, causing another UTI.

Medicine

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Plastic Surgery, Reconstructive Surgery, Cosmetic Surgery, Masectomy, Breast Reconstruction, Immediate breast reconstruction (IBR)

Different Databases, Differing Statistics on Racial Disparities in Immediate Breast Reconstruction After Mastectomy

Three major national databases include varying estimates of racial gaps in the use of immediate breast reconstruction (IBR) after mastectomy for breast cancer, reports a study in the March issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Medicine

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Periodontal Disease, Periodontist, Cardiovascular Disease, Women, Aging, Mortality, Epidemiology

Study: Gum Disease, Tooth Loss May Increase Postmenopausal Women’s Risk of Death

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Findings suggest that older women may be at higher risk for death because of their periodontal condition and may benefit from more intensive oral screening measures.

Medicine

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Adverse Childhood Experiences, Menopause, Depression, Womens' Health, Major depressive disorder (MDD) , Penn Medicine, Traumatic Experiences , Psychiatry

Trauma and Stress in Teen Years Increases Risk of Depression During Menopause, Penn Study Shows

First-of-its kind study finds number of traumatic experiences and when they first occur significantly affects the risk of depression during menopause

Medicine

Science

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Genomics, Fertilization process, Molecular Biology, zygote

Unique Genome Architectures After Fertilisation in Single-Cell Embryos

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo. Their findings have recently been published in the journal Nature. The team of researchers (from three continents) have discovered that the egg and sperm genomes that co-exist in the single-cell embryo or zygote have a unique structure compared to other interphase cells. Understanding this specialized chromatin “ground state” has the potential to provide insights into the yet mysterious process of epigenetic reprogramming to totipotency, the ability to give rise to all cell types.

Medicine

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Northwestern University, Northwestern University Feinberg School of Medicine, Women's Health

Female Menstrual Cycle in a Dish

Northwestern Medicine has developed a miniature female reproductive tract that fits in the palm of your hand and could eventually change the future of research and treatment of diseases in women’s reproductive organs.This new 3-D technology — called EVATAR — is made with human tissue and will enable scientists to conduct much-needed testing of new drugs for safety and effectiveness on the female reproductive system.

Medicine

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Breast Cancer, Inflammatory Breast Cancer, Bisphenol A (BPA), Bisphenol A, BPA

Study Shows How BPA May Affect Inflammatory Breast Cancer

The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute.







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