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Medicine

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Breast Cancer, Cancer Biomarkers, Genomics, cancer disparities, cancer drug resistance, cancer drug development

UCSF Researchers Awarded Breast Cancer Research Funding From Susan G. Komen

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Three UCSF researchers have been awarded $680,000 in grants from Susan G. Komen to support projects in breast cancer research. The grants to UCSF were among a total of $32.7 million given to researchers in 23 states and seven countries for projects including research into metastatic disease, novel treatments for aggressive types of breast cancer, new technologies, and health equity.

Medicine

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antibiotic resisistance, Antibiotic Resistant Bacteria, Keratitis, Superbug, Superbugs

Mass. Eye and Ear Team Discovers, Successfully Treats New Variant of Antibiotic-Resistant Bacterium

Researchers at Massachusetts Eye and Ear have discovered a new mutation in a highly antibiotic-resistant strain of E. coli that resists clearance by the body’s own immune system by inhibiting white blood cells that ordinarily kill and remove bacteria. In a paper published online today in JAMA Ophthalmology, the researchers describe the case that led them to discover the mutation, and offer suggestions for how to recognize and address this particular microbe if encountered in the future.

Medicine

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Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Tisch Cancer Institute, Ras inhibitor, KSR, Nature, Cancer Therapeutics, Cancer Therapies, Oncogene

Mount Sinai Researchers Identify New Therapeutic Target for Cancer

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies. The protein, known as kinase suppressor of Ras, or KSR, is a pseudoenzyme that plays a critical role in the transmission of signals in the cell determining whether cells grow, divide, or die.

Medicine

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Mouse Model Points to Potential Drug Target for Increasing Social Interaction in Autism

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A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder.

Science

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clinical trial, Parkinson's Disease, Type 2 Diabetes

Diabetes Drug Focus of New Clinical Trial for Parkinson’s Disease

Type II diabetes and Parkinson’s disease may not appear to have much in common but a look below the surface reveals important molecular similarities that provide a potential target for fighting Parkinson’s.

Medicine

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antidepessant medication, Antidepressant

Antidepressant Bone Loss Could Be Prevented with Beta-Blockers

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The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found.

Medicine

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Ginger, nano-lipids , Nanoparticles, Chemotherapeutic Drugs, Colon Cancer, Colorectal Cancer, Georgia State University, Institute for Biomedical Sciences, Didier Merlin, Doxorubicin

Nano-Lipid Particles From Edible Ginger Could Improve Drug Delivery for Colon Cancer, Study Finds

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Edible ginger-derived nano-lipids created from a specific population of ginger nanoparticles show promise for effectively targeting and delivering chemotherapeutic drugs used to treat colon cancer, according to a study by researchers at the Institute for Biomedical Sciences at Georgia State University, the Atlanta Veterans Affairs Medical Center and Wenzhou Medical University and Southwest University in China.

Medicine

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Chroni Non Cancer Pain, complex regional pain syndrom, opioid alternatives, Spinal Cord Stimulation, dorsal root ganglia, Pain Managament

Outpacing Pain: New Relief for Complex Regional Pain Syndrome

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Rush University Medical Center ’ Dr. Timothy Lubenow is first doctor in country to use a more advanced form of spinal cord stimulation that sends electrical pulses to Dorsal Root Ganglia; 90+ percent of chronic pain patients report substantial relief.

Medicine

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Ophthalmology, Glaucoma, Contact Lens, drug delivery platform

Drug-Dispensing Contact Lens Effectively Lowers Eye Pressure in Pre-Clinical Glaucoma Model

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A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer. In a study published online today in Ophthalmology, a team of researchers have shown that a novel contact lens-based system, which uses a strategically placed drug polymer film to deliver medication gradually to the eye, is at least as effective, and possibly more so, as daily latanoprost eye drops in a pre-clinical model for glaucoma.

Medicine

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sertraline, sertrali, MIND Institute, Uc Davis, SSRI

Sertraline, Brand Named Zoloft, Improves Functioning in Young Children with Fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.

Medicine

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Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Pathology, Carlos Cordon-Cardo, Precise MD

Mount Sinai Establishes Center for Computational and Systems Pathology

Researchers will contribute cutting-edge innovation in personalized precision medicine

Medicine

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Medication, Fracture, Gerontolgoy, psychotropic medication, Osteoporosis

After a Fracture, It’s Time to Rethink Medications

By discouraging the use of medications that can cause dizziness or loss of balance and prescribing medications known to prevent bone loss, clinicians can help patients lower their risk of falls and fractures.

Medicine

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pain care, Medical Marijuana, cannabis research

Smoking Marijuana Provides More Pain Relief for Men Than Women

Researchers from Columbia University Medical Center found that men had greater pain relief than women after smoking marijuana. “These findings come at a time when more people, including women, are turning to the use of medical cannabis for pain relief,” said Ziva Cooper, PhD, one of the authors...

Medicine

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Type 2 Diabetes, Pharmacogenomics, Metformin, Genetics

Gene Variant Explains Differences in Diabetes Drug Response

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A large international study of metformin, the world’s most commonly used type 2 diabetes drug, reveals genetic differences among patients that may explain why some respond much better to the drug than others.

Medicine

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Jersey Shore University Medical Center is First Hospital in New Jersey to offer Deep Transcranial Magnetic Stimulation (dTMS)

Jersey Shore University Medical Center is the first hospital in New Jersey to offer deep transcranial magnetic stimulation (dTMS) – a non-invasive treatment for depression that provides new hope for patients who have experienced side effects from medications or for whom medications have proven ineffective.

Medicine

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genetic, Epigenetic, Disparities, Health Policy

Researchers Turn to Policy to Tackle Health Disparities in an Age of Personalized Medicine

Genetic research is a valuable tool in understanding diseases and their prevention, diagnosis, and treatment. However, significant obstacles limit the clinical use of this knowledge to all groups. Genetic applications in healthcare must advance in a way that reduces racial and ethnic disparities.

Medicine

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Infection Control, Wound Care, Trauma

UM-Madison Spinoff Gets FDA OK for Bacteria-Killing Wound Dressing

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MADISON, Wis. — Imbed Biosciences today received clearance from the Food and Drug Administration to market its patented wound dressing for human use.

Medicine

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Hypertension, Renal denervation, clinical trial for hypertension

UH Case Medical Center Treats First Patient in the World on International Clinical Trial for Hypertension

University Hospitals Case Medical Center is the first site in the world to perform a procedure on a patient in RADIANCE-HTN, an international clinical trial evaluating the effect of the ReCor Paradise® Renal Denervation System on lowering blood pressure with hypertension. The system uses ultrasound energy to treat overactive nerves leading to the kidney.RADIANCE-HTN is a blinded, randomized, sham-controlled trial.

Medicine

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University At Buffalo, Pharmacy, Online Medicine, Medicine, Consumer Safety, SUNY, Pharmacist, Prescription Drug, Prescription Adherence

Medicine Is the One Item You Should Never Buy Online, Says UB Pharmacy Practice Expert

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The convenience of purchasing medicine online does not outweigh the risks, says Karl Fiebelkorn, University at Buffalo pharmacy practice expert.

Medicine

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Study Shows Distress Intolerance Associated with Opioid Misuse

Inability to manage negative emotional and somatic stress is associated with opioid misuse in adults with chronic pain, according to new research reported in The Journal of Pain, published by the American Pain Society,







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