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New Avenue for Anti-Depressant Therapy Discovered

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Researchers have made a ground-breaking discovery revealing new molecular information on how the brain regulates depression and anxiety. In so doing, they identified a new molecule that alleviates anxiety and depressive behaviour in rodents.

Medicine

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Depression, antidepressant drugs , Pregnancy, Women, Babies, Birth Defects, Montreal, Quebec, Celexa, Paxil, Congenital Malformations, Psychiatry, Psychotherapy, Exercise

New Data Show Heightened Risk of Birth Defects with Antidepressants Prescribed During Pregnancy

A new Université de Montréal study in the British Medical Journal reveals that antidepressants prescribed to pregnant women could increase the chance of having a baby with birth defects.

Medicine

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Opioids, opioid abuse, Opioid Abuse Epidemic, Opioid Addiction

UVA Slashes Opioid Use While Improving Pain Scores, Study Finds

A study of more than 100,000 surgical cases at University of Virginia Health System found patients’ pain scores improved even as doctors gave fewer opioids. As health officials across the U.S. look for ways to combat a opioid addiction crisis, UVA researchers believe their findings highlight one way to address the problem.

Medicine

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Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Oxycodone, RGS9-2, Chronic Pain, brain reward center, Analgesia, Mu Opioid, opioid receptor signaling, opioid receptors, acute pain, Morphine, Neuropathic Pain

Key Signaling Protein Associated with Addiction Controls the Actions of Oxycodone in Pain-Free and Chronic Pain States

RGS9-2, a key signaling protein in the brain known to play a critical role in the development of addiction-related behaviors, acts as a positive modulator of oxycodone reward in both pain-free and chronic pain states

Medicine

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immunotheraphy, Obesity, Medical Research

Mayo Clinic Researchers Identify Cancer-Fighting Drugs That Help Morbidly Obese Mice to Lose Weight

Scientific investigations sometimes result in serendipitous discoveries which shift the investigations from one focus to another. In the case of researchers at Mayo Clinic in Arizona, studies addressing obesity’s impact on cancer treatment resulted in an unexpected discovery that shifted the focus from cancer to obesity.

Medicine

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TTUHSC El Paso, Propranolol, Brad Bryan, Anticancer Fund, orphan drug designation, orphan drug, Rare Diseases, Soft Tissue Sarcoma, angiosarcoma, Soft Tissue Sarcomas, Angiosarcomas, Texas Tech University Health Sciences Center El Paso, Europe, Eddy Pasquier, Shripad Banavali, Pan Pantziarka

Common Heart Drug Repurposed to Treat Rare Cancer in Europe

A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).

Medicine

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Miami Doctors Publish Study of First Locally-Acquired Zika Transmission, Despite Low Profile, Zika Remains a High Concern, T Cells Join the Fight Against Zika, and More in the Zika Virus News Source

Get the latest on Zika in the Zika Virus News Source

Medicine

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Common Epilepsies Share Genetic Overlap with Rare Types

Researchers at Columbia University Medical Center and NewYork-Presbyterian showed that several genes implicated in rare forms of pediatric epilepsy also contribute to common forms of the disorder.

Medicine

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hematology oncology pharmacy, medically underserved areas, pharmacy and medically underserved areas enhancement act

HOPA Applauds Reintroduction of Pharmacy and Medically Underserved Areas Enhancement Act

The Hematology/Oncology Pharmacy Association (HOPA) applauds Senators Chuck Grassley (R-IA), Susan Collins (R-ME), Sherrod Brown (D-OH), and Bob Casey (D-PA) for introducing S. 109, the Pharmacy and Medically Underserved Areas Enhancement Act.

Science

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Pharmaceucticals, Biochemistry, Proteins, formalism, Biomolecules, Cells, Drugs, drugs design

U of A Chemist Develops New Theory for Explaining the Function of Proteins

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A University of Arkansas chemist and his collaborator at North Carolina State University have developed a new theory for explaining how proteins and other biomolecules function based on movement and change of shape and structure rather than content.

Medicine

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fetal medicine, Neonatal Medicine, Children's Hospital Los Angeles

Philippe Friedlich Named Division Chief at Children’s Hospital Los Angeles

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Philippe Friedlich, MD, MSEpi, MBA, has been selected as division chief of Neonatology and director of the Center for Fetal and Neonatal Medicine (CFNM) at Children’s Hospital Los Angeles.

Medicine

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Pharmaceutical Industry, Drug Development

Now Entering 'the Valley of Death'

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Amid Trump comments and stock dive, let WUSTL expert on the history of the pharmaceutical industry Michael Kinch walk you through pharma "Valley of Death."

Life

Law and Public Policy

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Trump, Donald Trump, drug prices, drug pricing, Pharmaceuticals

WashU Expert: Trump Has No Clear Plan for Reducing Drug Prices

Despite announcing in his first press conference that he would deal with a pharmaceutical industry “getting away with murder,” President-elect Donald Trump doesn’t seem to have a clear path for how he will reduce drug prices, said Rachel Sachs, associate professor of law at Washington University in St.

Medicine

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Warfarin, Blood Thinner, EHR

Changes to Hospital Electronic Health Records Could Improve Care of Patients on Popular Blood Thinner

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Warfarin is a commonly prescribed blood thinner used to prevent harmful blood clots. However, the drug requires frequent monitoring, daily dosing and can result in serious negative effects when mixed with vitamin K, a vitamin commonly found in vegetables such as lettuce or broccoli. Now, a new study from University of Missouri Health Care has found that using electronic health records (EHR) can improve the care patients receive after they leave the hospital and eliminate potential confusion among care providers and pharmacists.

Medicine

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Bacteria, Streptococci, Medicinal Chemistry, Pharmacognosy

Manipulating Signals in Bacteria Could Reduce Illnesses

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The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated.

Medicine

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Fundraiser, Billion dollar campaign, Billion Dollar Challenge, The Princess Margaret Cancer Foundation., princess margaret cancer centre, University Health Network

The Princess Margaret Successfully Achieves Historic Billion Dollar Challenge for Personalized Cancer Medicine

The Princess Margaret Cancer Foundation is thrilled to announce the successful achievement of our Billion Dollar Challenge, in partnership with the Princess Margaret Cancer Centre at University Health Network.

Medicine

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Drug Costs, New York University Rory Meyers College of Nursing

NYU Meyers Nursing Researcher Calls for Nursing Advocacy Surrounding Prescription Drug Price Increases

NYU Meyers Nursing Clinical Professor Sally S. Cohen makes a pitch for nurses to understand how perscription drug price increases affect patients and urges them to learn about the economics and politics of prescription drug costs. Cohen advocates for nurses to become more involved in this conversation.

Science

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Cancer, Malaria, Chloroquine, clinical trial

New Study Shows Promise for Repurposing Anti-Malarial Drug for Cancer Treatment

A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers.

Medicine

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Folic Acid, Folic Acid Intake, Birth Defects, Spina Bifida, Anencephaly, fortified flour, UTHealth , uthealth school of public health

Daily Folic Acid Supplementation Remains Important for Prevention of Birth Defects

Despite the mandatory addition of folic acid to enriched grain products in the United States, many women still do not consume adequate amounts of this important vitamin, according to an editorial written by Laura E. Mitchell, Ph.D., professor in the Department of Epidemiology, Human Genetics and Environmental Sciences at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.

Medicine

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Veterans, Opioid, Painkiller, Prescribing Patterns, Chronic pain treatment, Audit and feedback

National VA Effort Reduced Risky Opioid Prescriptions for Veterans, Study Finds

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Fewer veterans received prescriptions for risky dosages of opioid painkillers after a national VA initiative took aim at reducing high doses and potentially dangerous drug combinations, a new study finds. Over a two-year period, high-dose opioid prescribing declined by 16 percent, and very-high-dose opioid prescribing dropped by 24 percent.







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