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Medicine

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Diabetes, Glucose, Type 2 Diabetes, Type 1 Diabetes, Ut Southwestern, Ghrelin

Research Elucidates Ghrelin’s Role in Blood Glucose Regulation, a Finding with Implications for Treating Diabetes

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UT Southwestern research investigating the blood glucose-regulatory actions of the hormone ghrelin may have implications for development of new treatments for diabetes.

Medicine

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Inflamamatory Bowel Disease (Ibd), Crohn's Disease, Ulcerative Colitis, Microrna, inflammasome

Researchers Uncover Key Role for MicroRNA in Inflammatory Bowel Disease

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An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, “Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome,” which will be published May 9 in The Journal of Experimental Medicine, shows that synthetic versions of this microRNA can reduce intestinal inflammation in mice and suggests a new therapeutic approach to treating patients with Crohn’s disease or ulcerative colitis.

Medicine

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Diabetes, Biomedical Engineering, Research, Insulin, Blood, Smart medical systems, Drug Delivery

Researchers Use Modified Insulin and Red Blood Cells to Regulate Blood Sugar

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Researchers have developed a new technique that uses modified insulin and red blood cells to create a glucose-responsive “smart” insulin delivery system. In an animal model study, the new technique effectively reduced blood sugar levels for 48 hours in a strain of mice that had Type 1 diabetes.

Medicine

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Dana Farber Cancer Institute, AML, Leukemia, Acute Myeloid Leukemia, Cancer, Blood Cancers, FDA, Chemotherapy

Backed by Dana-Farber Research, FDA Approves New AML Drug

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

Medicine

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Omega 3 Fatty Acids, blood-brain barrier, Blood Cells, Lipids, Cells, central nervous system, Transcytosis, Mfsd2a, Delivering Drugs, Drugs and the Brain, Brain, Chenghua Gu, Neurobiology, Harvard Medical School, Blood Vessels, Endothelial Cells

Unlocking the Barrier

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At a glance: · New study reveals that blood-brain barrier function relies on the balance between omega-3 fatty acids and other lipids in cells that line blood vessels in the central nervous system. · This lipid make-up keeps the barrier closed by inhibiting the formation of vesicles that shuttle molecules across cells, a process known as transcytosis. · Low levels of vesicles are maintained by the lipid transport protein Mfsd2a. · Disrupting Mfsd2a may be a strategy for opening the blood-brain barrier to deliver drugs into the brain.

Medicine

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Brain Cancer, Diabetes, Glioma, Blood Sugar, Blood Glucose

Surprising Link Between Blood Sugar and Brain Cancer Found

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.

Medicine

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Type 1 Diabetes, Type 1 Diabetes Clinical Trial, artificial pancreas

Artificial Pancreas Benefits Young Children, Trial Shows

A pilot study among young children with Type 1 diabetes found that a University of Virginia-developed artificial pancreas helped study participants better control their condition.

Medicine

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American Society for Nutrition , Nutrition, Sodium, Potassium, Sodium Reduction Guidlines, Calcium, Magnesium, Dietary Guidelines For Americans, Blood Pressure, salt, Framingham Offspring Study, Cardiovascular Health

Low-Sodium Diet Might Not Lower Blood Pressure

A new study that followed more than 2,600 men and women for 16 years found that consuming less sodium wasn’t associated with lower blood pressure. The study adds to growing evidence that current recommendations for sodium intake may be misguided.

Medicine

Science

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AANS Annual Scientific Meeting, AANS, American Association of Neurological Surgeons, Cerebral Ischemia, Subarachnoid Hemorrhage

White Blood Cell Count and Neutrophil‑lymphocyte Ratio Improve Prediction of Delayed Cerebral Ischemia in Good‑grade Subarachnoid Hemorrhage

Winner of the DePuy Synthes Cerebrovascular Award, Fawaz Al-Mufti, MD, presented his research, White Blood Cell Count and Neutrophil‑lymphocyte Ratio Improve Prediction of Delayed Cerebral Ischemia in Good‑grade Subarachnoid Hemorrhage, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.

Business

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La Jolla Institute for Allergy and Immunology

LJI Professor Klaus Ley Wins Prestigious National Award

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Professor Klaus Ley, M.D., has been selected as this year’s winner of the Eugene M. Landis Award, the Microcirculatory Society’s top honor, in recognition of his pioneering work in vascular biology and microcirculation. The microcirculation comprises all the small blood vessels in all tissues and organs and their contents (blood plasma and blood cells).







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