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Medicine

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Tumor Necrosis Factor, Heart Disease, Inflammatory Disease, Ted Rogers Centre for Heart Research

Tumor Necrosis Factor Found to Directly Regulate Blood Pressure

Ted Rogers Centre for Heart Research study is first to show TNF operating beyond immune system, Caution needed when administering anti-TNF medications

Medicine

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x-ray free-electron laser, x-ray crystallography, Structural Biology, Blood Pressure, Sodium, Cell Biology and Physiology

X-Ray Study Reveals Long-Sought Insights Into Potential Drug Target

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Many hypertension medications currently on the market target the AT1 receptor because of its well-understood role in blood pressure regulation; they block AT1 in order to reduce blood pressure. The AT2 receptor, on the other hand, is still an elusive drug target despite multiple studies of its function. Now, researchers have solved its structure to hone in on its function. The results of the experiments were surprising in several ways. First, although both compounds were designed to block and deactivate the receptors, they left AT2 in a state that appeared to be active. In addition, although AT1 and AT2 were thought to be very similar, the pockets where the receptors bind to the compounds exhibited marked differences.

Medicine

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Blood Pressure, Blood Pressure Diet, Diet, Potassium, Potassium in Diet, Stroke, Heart Disease, Hypertension, Sodium, Keck School Of Medicine Of Usc, Research, Food Labeling, dietary evolution, Biology, cell, Fruits And Vegetables, Coffee

Fruits and Vegetables’ Latest Superpower? Lowering Blood Pressure

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A new study from the Keck School of Medicine of USC links increased dietary potassium with lower blood pressure.

Medicine

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PAD, Peripheral Arterial Disease, Vascular Disease

First U.S. Patient Treated in Landmark Vascular Study of Lithoplasty® Technology

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PinnacleHealth CardioVascular Institute enrolled the first patient in the United States in a trial assessing the safety and effectiveness of a new type of approach for blockages in the leg artery. DISRUPT PAD III is the largest ever multi-center randomized study to exclusively enroll patients with calcified peripheral artery disease (PAD).

Medicine

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Autism, ASD, Biomarker, Diagnosis, Rensselaer, Metabolites, Algorithm, Machine Learning, Juergen Hahn

A Blood Test for Autism? Rensselaer Researcher Juergen Hahn Available to Comment on Using an Algorithm and 24 Metabolites to Diagnose ASD

Medicine

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artificial pancreas, Insulin, Type 1 Diabetes, Children, Blood Sugar, Insulin Pump, Continuous Glucose Monitoring Systems, ENDO 2017, Endocrine Society, Endocrinology, Diabetes, Diabetes & Endocrinology, Diabetes Technology, Pediatric

Artificial Pancreas Improves Blood Sugar Control in Young Kids

An artificial pancreas, which delivers insulin in an automated way to individuals with type 1 diabetes, appears to be safe and effective for use in children ages 5 to 8 years, a new study finds. Results will be presented Tuesday at the Endocrine Society’s 99th annual meeting in Orlando, Fla.

Medicine

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Heart Disease Risk, Heart Disease, Heart Failure, UT Southwestern

These 5 Tests Better Predict Heart Disease Risk

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Five simple medical tests together provide a broader and more accurate assessment of heart-disease risk than currently used methods, cardiologists at UT Southwestern Medical Center found.

Medicine

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march for science, Endocrine Society, National Institutes Of Health (NIH), Science Funding, Biomedical Research, Federal Budget, Endocrinology, Hormone

Endocrine Society Joins March for Science

The Endocrine Society is proudly partnering with the March for Science, which will bring together more than 100 scientific organizations on Saturday, April 22 to celebrate science and rally public support for publicly funded research.

Medicine

Science

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Collagen, Blood Vessels, tissue implant, replantation, Linker, Tissue Engineering, microsuture, Microsurgery, Vascular Grafts

Tiny Bioengineered Blood Vessel Grafts Aid Delicate Microsurgeries

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Scientists have been working diligently to create engineered tissue implants to repair or replace damaged or diseased tissue and organs; but their success hinges on the ability to build a sturdy connection linking the implant’s blood vessels and the patient’s existing vasculature. National Institute of Biomedical Imaging and Bioengineering (NIBIB)-funded researchers have created segments of engineered blood vessels to address this critical issue.

Medicine

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Scientists Discover New Class of Anti-Diabetes Compounds That Reduce Liver Glucose Production

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A team of scientists from the Florida campus of The Scripps Research Institute (TSRI), Dana-Farber Cancer Institute, Harvard Medical School and the Yale University School of Medicine, among others, have identified a new class of compounds that reduce production of glucose in the liver.







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