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Drug Resistance

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Medicine

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Microbiology, Fungus, antibacterial resistance

First Cases of Deadly, Drug-Resistant Fungus Reported in US by CDC

The deadly fungus, Candida auris, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected. Now, in a first-of-its-kind study, microbiologists at Case Western Reserve University School of Medicine have provided previously uninvestigated details pertaining to C. auris drug resistance and growth patterns.

Medicine

Channels:

Antibiotic Resistance

Novel Antibiotic Combination Therapy Overcomes Deadly Drug-Resistant Bacteria

Researchers in Cleveland, Ohio have taken a significant step toward defeating antibiotic-resistant infections by combining two different antibiotics that each block a different kind of drug-destroying enzyme secreted by bacteria.

Medicine

Channels:

Center for Biomedical Discovery, Chemotherapy resistance, discovery research, Kinase, Dr. Haojie Huang, Foxo1

Mayo Clinic Researchers Clarify Chemo Resistance, and Perhaps a New Therapy

Mayo Clinic scientists have identified a specific protein implicated in drug resistance, as well as a possible therapeutic tool. Their work appears in the EMBO Journal.

Medicine

Channels:

drug adverse events, Abacavir, Antiviral Drugs, HIV, abacavir hypersensitivity syndrome, Computer Modeling, HLA-B*57:01, Immune Response

Computer Models Could Allow Researchers to Better Understand, Predict Adverse Drug Reactions

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Computer model shows what happens at the molecular level during severe allergic reactions to abacavir, a common HIV drug

Medicine

Channels:

Infectious Diseases, Superbugs, Antibiotics, Antibiotic Resistance, Gram-Negative Bacteria, off-patent drugs , pentamidine, Acinetobacter baumannii , Enterobacteriaceae

One-Two Punch May Floor Worst Infections

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The scientists discovered the antiprotozoal drug pentamidine disrupts the cell surface of Gram-negative bacteria, even the most resistant. The anti-fungal medication was particularly potent when used with antibiotics against multidrug resistant bacteria.

Life

Social and Behavioral Sciences

Channels:

mental, disorders, psychotropic

Patients More Likely to Refuse Drug Therapy Than Psychotherapy for Mental Health

People seeking help for mental disorders are more likely to refuse or not complete the recommended treatment if it involves only psychotropic drugs, according to a review of research published by the American Psychological Association.

Medicine

Channels:

Antibiotic Resistance, Infectious Disease, Microbiology, Molecular Biology

Cleveland Takes New Steps to Tackle “Superbugs”

Case Western Reserve University School of Medicine and Louis Stokes Cleveland VA Medical Center are teaming up to take on the rising problem of antibiotic resistance.

Medicine

Channels:

Superbugs, Antibiotic Resistance, drug pipeline

Expert on Drug Discovery Available to Speak on the WHO List of Superbugs

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Medicine

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Scientists Unveil Why Microbe Klebsiella, Cited as an Urgent Threat to Human Health by WHO, Is Resistant to Antibiotics.

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Medicine

Science

Channels:

Drug Resistant Bacteria, Infectious Diseases, Glass, Superbugs, World Health Organization

Microbiology Expert Available to Discuss Use of Glass to Limit Spread of Drug-Resistant Bacteria

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