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Stem Cells

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Medicine

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Chulan Kwon, heart muscle, Stem Cells, Rat, rrhythmogenic right ventricular cardiomyopathy, Arvc

Mature Heart Muscle Cells Created in the Laboratory From Stem Cells

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Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists.

Medicine

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Biomedical Engineering, Myocardial Infarction, Heart Attack, Cell Therapy, Stem Cell, human induced pluripotent stem cells

Tissue Engineering Advance Reduces Heart Failure in Model of Heart Attack

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Cardiac muscle patches in this proof-of-concept research may represent an important step toward the clinical use of 3-D-printing technology, as researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold made with a 3-D printer.

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Researchers Discover BRCA1 Gene Is Key for Blood Forming Stem Cells

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Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia. The stem cells die before they have an opportunity to transform into a blood cancer.

Medicine

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Stem Cells, Immunotherapy, Cancer, zika virus, Infectious Diseases, Pregnancy, Public Health, Pediatrics, Neurology, Natural Killer Cells

CIRM Approves New Funding to UC San Diego Researchers Fighting Zika Virus and Cancer

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The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer (NK) cells to target ovarian cancer and other malignancies.

Science

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Bioethics, Organoids, Human Embryonic Stem Cells, Animal Testing, Tissue Engineering, Regenerative Medicine

Scientists Initiate First Ethical Guidelines for Organs Cultivated in Vitro

In the latest edition of the journal “Science”, Jürgen Knoblich, a leading authority on stem cells and deputy director of the IMBA (Institute for Molecular Biotechnology of the Austrian Academy of Sciences), together with international experts, presents a first ethical guideline for research into human organ models. In the article, he also argues for critical and responsible engagement with the new technology.

Medicine

Science

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Biology, Cancer, Protein, Lipid, Fat, Stem Cells, Molecular Biology, Chemistry, waxes, triacylglycerols, Aging, Senescent

As Cells Age, the Fat Content Within Them Shifts

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As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids. By providing broad insights into the connection between lipids and cellular aging, the findings open the door for additional research that could one day support the development of lipid-based approaches to preventing cell death or hastening it in cancerous tumors.

Science

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super-resolution microscopy, stem cell differentiation

Super-Resolution Imaging Offers Fast Way to Discern Fate of Stem Cells

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Scientists funded by the National Institutes of Health have developed a new way to identify the state and fate of individual stem cells earlier than previously possible.

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Miami Doctors Publish Study of First Locally-Acquired Zika Transmission, Despite Low Profile, Zika Remains a High Concern, T Cells Join the Fight Against Zika, and More in the Zika Virus News Source

Get the latest on Zika in the Zika Virus News Source

Medicine

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Graft-versus-host disease

Moffitt Cancer Center Researchers Develop Novel Treatment to Prevent Graft-Versus-Host-Disease

TAMPA, Fla. – Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.  In a new study published as the cover story in Science Translational Medicine, Moffitt Cancer Center researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.

Medicine

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In Vitro Gametogenesis, IVG, Reproductive Technology, Experimental Reproductive Technology, Infertility Treatments, Infertility, Embryonic Stem Cell, IVG Legality, Experimental Technique, Experimental, Embryo, IVG Therapy, gene modification, Reproductive Legality

The Promise and Peril of Emerging Reproductive Technologies

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In-vitro gametogenesis is an experimental technique that allows scientists to grow embryos in a lab by reprograming adult cells to become sperm and egg cells.







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