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Personalized Medicine

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Medicine

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Neuroscience, precision neuroscience, Personalized Medicine, Virginia Tech Carilion Research Institute, Virginia-Nordic Precision Neuroscience, Sunnaas Rehabilitation Hospital, University of Oslo, Roanoke

International Scientists Join Forces to Put ‘Precision’ Focus on Neuroscience

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For three days this week, Roanoke, Virginia, is the capital of the precision neuroscience world. The top minds of precision neuroscience are coming together in a think-tank setting to explore the challenges and promise of bringing personalized medicine to brain health.

Medicine

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Center for Individualized Medicine, Dna Sequencing, Medical Research, whole exome sequencing, Molecular Testing

4 Ways Individualized Medicine Can Be Applied Immediately to Patient Care

Individualized medicine is no longer the lore of science fiction. It is offering new hope for patients with cancer, heart disease, depression and rare diseases for which there historically have been no diagnosis or treatment. And that’s just the beginning.

Medicine

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Center for Individualized Medicine, Dna Sequencing, Medical Research, Minnesota News Releases, Molecular Testing, news releases, Pharmacogenomics, Precision Medicine

Mayo Clinic Patient: ‘Individualized Medicine Saved My Life’

What Karen Daggett didn’t know almost killed her. The medicine she relied on to control an irregular heartbeat wasn’t working and hadn’t for years and she didn’t understand why pain medication never seemed to make her feel better. She also had a history of not tolerating some over-the-counter medications. Silently, these drugs were building up in her system, causing harmful side effects until DNA testing at Mayo Clinic Center for Individualized Medicine showed some medications were incompatible with her genetic makeup.

Medicine

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Alzheimer's Disease, Georgetown University Medical Center, Howard Fillit, Nilotinib, repurposing cancer drugs, R. Scott Turner, Chronic Myeloid Leukemia, Cognitive Impairment, Neuroinflammation, misfiled proteins, atophagy, plaques and tangles, tau, beta-amyloid, Charbel Moussa, Georgetown Memory Disorders Program, anti-neurodegenerative drug, Georgetown U

New Clinical Trial Will Test Cancer Drug as Alzheimer’s Treatment

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The Alzheimer’s Drug Discovery Foundation (ADDF) announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna® for use as a cancer therapy) in patients with Alzheimer’s disease.

Medicine

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Hepatitis, Hepatitis B, Hepatitis B research, Hepatitis B Virus, hepatitis B virus (HBV), pharmacological research, Pharmacology, Pharmacologic, pharmacologic compound, pharmacology and therapeutics, Drug Research, Drug Research and Development

NIH Grants MU $3 Million to Develop New Hepatitis B Treatments

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Hepatitis B (HBV) is a viral infection that increases the likelihood of developing liver cancer or liver failure. According to the World Health Organization, an estimated 2 billion people currently are infected with HBV, which is more than 10 times the number of people who have human immunodeficiency virus (HIV). Currently, treatment for hepatitis B infections is limited to one class of drugs that targets the virus. Stefan Sarafianos, an investigator with the University of Missouri Bond Life Sciences Center (BLSC) recently was awarded $3 million from the National Institutes of Health to study the disease. Building on existing research, he and his team will work on the development of new drugs to treat HBV.

Medicine

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Inside the Lab: Using Botox to Advance Science

Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.

Medicine

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drug deliver, Tumor, Cancer, magnetic bacteria

Swarms of Magnetic Bacteria Could Be Used to Deliver Drugs to Tumors

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Researchers have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs.

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Drug Restores Hair Growth in Patients with Alopecia Areata

Seventy-five percent of patients with an autoimmune disease that causes hair loss had significant hair regrowth after treatment with ruxolitinib, according to a study from Columbia University Medical Center.

Medicine

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Breast Cancer, Cancer Biomarkers, Genomics, cancer disparities, cancer drug resistance, cancer drug development

UCSF Researchers Awarded Breast Cancer Research Funding From Susan G. Komen

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Three UCSF researchers have been awarded $680,000 in grants from Susan G. Komen to support projects in breast cancer research. The grants to UCSF were among a total of $32.7 million given to researchers in 23 states and seven countries for projects including research into metastatic disease, novel treatments for aggressive types of breast cancer, new technologies, and health equity.

Medicine

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antibiotic resisistance, Antibiotic Resistant Bacteria, Keratitis, Superbug, Superbugs

Mass. Eye and Ear Team Discovers, Successfully Treats New Variant of Antibiotic-Resistant Bacterium

Researchers at Massachusetts Eye and Ear have discovered a new mutation in a highly antibiotic-resistant strain of E. coli that resists clearance by the body’s own immune system by inhibiting white blood cells that ordinarily kill and remove bacteria. In a paper published online today in JAMA Ophthalmology, the researchers describe the case that led them to discover the mutation, and offer suggestions for how to recognize and address this particular microbe if encountered in the future.

Medicine

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Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Tisch Cancer Institute, Ras inhibitor, KSR, Nature, Cancer Therapeutics, Cancer Therapies, Oncogene

Mount Sinai Researchers Identify New Therapeutic Target for Cancer

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies. The protein, known as kinase suppressor of Ras, or KSR, is a pseudoenzyme that plays a critical role in the transmission of signals in the cell determining whether cells grow, divide, or die.

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Mouse Model Points to Potential Drug Target for Increasing Social Interaction in Autism

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A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder.

Science

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clinical trial, Parkinson's Disease, Type 2 Diabetes

Diabetes Drug Focus of New Clinical Trial for Parkinson’s Disease

Type II diabetes and Parkinson’s disease may not appear to have much in common but a look below the surface reveals important molecular similarities that provide a potential target for fighting Parkinson’s.

Medicine

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antidepessant medication, Antidepressant

Antidepressant Bone Loss Could Be Prevented with Beta-Blockers

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The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found.

Medicine

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Ginger, nano-lipids , Nanoparticles, Chemotherapeutic Drugs, Colon Cancer, Colorectal Cancer, Georgia State University, Institute for Biomedical Sciences, Didier Merlin, Doxorubicin

Nano-Lipid Particles From Edible Ginger Could Improve Drug Delivery for Colon Cancer, Study Finds

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Edible ginger-derived nano-lipids created from a specific population of ginger nanoparticles show promise for effectively targeting and delivering chemotherapeutic drugs used to treat colon cancer, according to a study by researchers at the Institute for Biomedical Sciences at Georgia State University, the Atlanta Veterans Affairs Medical Center and Wenzhou Medical University and Southwest University in China.

Medicine

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Chroni Non Cancer Pain, complex regional pain syndrom, opioid alternatives, Spinal Cord Stimulation, dorsal root ganglia, Pain Managament

Outpacing Pain: New Relief for Complex Regional Pain Syndrome

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Rush University Medical Center ’ Dr. Timothy Lubenow is first doctor in country to use a more advanced form of spinal cord stimulation that sends electrical pulses to Dorsal Root Ganglia; 90+ percent of chronic pain patients report substantial relief.

Medicine

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Ophthalmology, Glaucoma, Contact Lens, drug delivery platform

Drug-Dispensing Contact Lens Effectively Lowers Eye Pressure in Pre-Clinical Glaucoma Model

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A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer. In a study published online today in Ophthalmology, a team of researchers have shown that a novel contact lens-based system, which uses a strategically placed drug polymer film to deliver medication gradually to the eye, is at least as effective, and possibly more so, as daily latanoprost eye drops in a pre-clinical model for glaucoma.

Medicine

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sertraline, sertrali, MIND Institute, Uc Davis, SSRI

Sertraline, Brand Named Zoloft, Improves Functioning in Young Children with Fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.

Medicine

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Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Pathology, Carlos Cordon-Cardo, Precise MD

Mount Sinai Establishes Center for Computational and Systems Pathology

Researchers will contribute cutting-edge innovation in personalized precision medicine

Medicine

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Medication, Fracture, Gerontolgoy, psychotropic medication, Osteoporosis

After a Fracture, It’s Time to Rethink Medications

By discouraging the use of medications that can cause dizziness or loss of balance and prescribing medications known to prevent bone loss, clinicians can help patients lower their risk of falls and fractures.







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