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Medicine

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drug, Drug Target, Drug Targets, Disease, Protein

Drugs, Diseases and Proteins: New Archive Helps Precision Medicine, Drug Development

Tudor Oprea, MD, PhD, at UNM Comprehensive Cancer Center and his collaborators from the UK-based European Bioinformatics Institute in Hinxton and from the Institute for Cancer Research in London have created the beginnings of an open archive that links a drug’s chemical structure, its molecular biology activity and the diseases it is used to treat.

Medicine

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Only FDA-Approved Device to Repair "Hole in the Heart" Condition Now Available at Baylor Heart and Vascular Services at Fort Worth

Baylor Heart and Vascular Services at Fort Worth on Tuesday, November 15, became the first program in Texas to implant the only FDA-approved device designed to prevent blood clots from entering the brain by sealing a hole in the heart. The device is designed to help reduce the risk of recurrent cryptogenic strokes in patients diagnosed with a patent foramen ovale (PFO) – a small opening between the upper chambers of the heart.

Medicine

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Society Of Toxicology, Toxicology, toxicologist, Annual Meeting, ToxExpo, data science, Precision Medicine, Epigenetic, Food Safety, Arsenic, Pesticide, Alternative Test Methods, Public Health, In Vitro, Organs-on-a-chip, Carcinogenesis, Air Pollution

Latest Research on Data Science, Precision Medicine, Epigenetics, Food Safety, Arsenic, Pesticides, Alternative Test Methods, and More Featured at SOT 56th Annual Meeting and ToxExpo

The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.

Medicine

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laboratory technology, cell reprogramming, Precision Medicine, Cancer Drug, Cells

Scientists Describe Lab Technique with Potential to Change Medicine and Research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

Medicine

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pulmospheres, Pulmonary, IPF, Idiopathic Pulmonary Fibrosis, Precision Medicine

Precision Medicine: UAB Study Creates ‘Mini-Lung’ to Study Effect of Pulmonary Fibrosis Drugs

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Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from UAB presented today in JCI Insight.

Medicine

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Breast Cancer, Ovarian Cancer, Prostate Cancer, olaparib, PARP inhibitors, Metabolism, Lung Cancer

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

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Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study “Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells,” which has been published in The Journal of Cell Biology, suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

Medicine

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pediatric endocrinology, Growth Hormone Deficiency, growth hormone treatment, IGF-I deficiency, Idiopathic Short Stature, ISS, Children's Hospital Of Philadelphia, Medical Ethics

When Should Doctors Treat Short Children and Teens with Growth Hormone?

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When is it appropriate to treat short children with growth hormone? The answer is not always clear-cut, as many parents and physicians weigh social, medical and ethical concerns. Experts in pediatric endocrinology have issued a new set of guidelines for managing children and teens who have growth failure.

Medicine

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Drug Discovery

Robert R. Meyer Foundation Gift Boosts Drug Discovery Efforts

The Robert R. Meyer Foundation is supporting Southern Research’s Drug Discovery program with a $500,000 gift that aims to accelerate efforts to find new treatments for unmet medical conditions and rare and neglected diseases.

Science

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A Quark Like No Other, Biophysics Plays Key Role in Immune System Signaling and Response, ALMA Reveals Sun in New Light, and MORE in the Physics News Source Sponsored by AIP

Click here to go directly to the Physics News Source Sponsored by AIP.

Medicine

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Wayne State University, NIH, Tinnitus, Otolaryngology

Wayne State University Research Team Develops New Diagnostic Tool to Identify Tinnitus in Animals

A team of researchers from Wayne State University has developed a behavioral tool that may significantly aid in understanding the underlying mechanisms of tinnitus, ultimately leading to new drugs and treatment methods.







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