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Science

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Gates Foundation, Grant Award, Taste, pharmaceutical compliance, Children, Bitter Taste Sensitivity, parasitic infections, Schistosomiasis, recurrent diarrhea, sensory science, taste cells, screening assays, develolping nations, Pharmaceuticals, Interdisciplinary Research, taste blockers

Monell Center Receives Funding to Develop Technologies to Improve Taste of Lifesaving Drugs

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The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

Science

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Nanomedicine, Hiv Prevention, Truvada, nanochannels, Drug Delivery, space nanomedicine

Houston Methodist Receives Award for Implantable HIV Drug Delivery Device

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The Houston Methodist Research Institute’s department of nanomedicine is the recipient of this year’s AIDS Foundation Houston Shelby Hodge Vision Award. Alessandro Grattoni, Ph.D., nanomedicine department chair at the Houston Methodist Research Institute, accepted the award during the World AIDS Day luncheon.

Medicine

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Nyu Langone, Perlmutter Cancer, Stephen Ross, Anthony Bossis, Jeffrey Guss, psilocbyin, Anxiety, Depression, magic mushroom, Psychotherapy, Death, Dying, Psychopharmacology

Single Dose of Hallucinogenic Drug Psilocybin Relieves Anxiety and Depression in Patients with Advanced Cancer

When combined with psychological counseling, a single dose of a mind-altering compound contained in psychedelic mushrooms significantly lessens mental anguish in distressed cancer patients for months at a time, according to results of a clinical trial led by researchers at NYU Langone Medical Center.

Medicine

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Concussion, mTBI, Rehabilitation, Treatment

After Concussion, Rest May Not Always Be the Best Medicine, Experts Say

Prescribed rest—both physical and mental—is the standard treatment for concussion. But a growing body of evidence suggests that a more active, targeted approach might provide better outcomes for some patients, reports a special article in the December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons (CNS). The journal is published by Wolters Kluwer.

Medicine

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Chemotherapy, Taxane, Bevacizumab, Maintenance Therapy, Metastatic Breast Cancer, HER2 Negative, Survival Rate, progression-free survival

Treatment Combination to Improve Survival in HER2-Negative Metastatic Breast Cancer

The study, “A Real-World Multicentre Retrospective Observational Study of Paclitaxel-Bevacizumab and Maintenance Therapy as First-Line Treatment for HER2-Negative Metastatic Breast Cancer,” was recently published in the Journal of Cell Physiology.

Science

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National Cancer Institute Awards Major Contract to Southern Research

/PRNewswire-USNewswire/ -- Southern Research has been awarded a new, five-year Indefinite-Delivery Indefinite-Quantity (IDIQ) contract from the National Cancer Institute (NCI) to investigate the pharmacokinetic properties of antitumor and other therapeutic agents of interest to the Division of Cancer Treatment and Diagnosis (DCTD) under NCI contract HHSN261201600021I. RFP number N02CM67000-11 was issued under full and open competition, which resulted in five IDIQ awards. Task orders will be competed among the five IDIQ Contractors in the award pool and placed off of the IDIQ as requirements arise.

Medicine

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Epilepsy, refractory epilepsy, Anticonvulsant Drugs, University Of Utah, University of Utah College of Pharmacy

$19.5 Million NIH Contract Targets Drug Development for Treatment-Resistant Epilepsy

The University of Utah College of Pharmacy’s Anticonvulsant Drug Development (ADD) Program has been awarded a five-year $19.5 million contract renewal with the National Institutes of Health (NIH) to test drugs to treat epilepsy.

Medicine

Life

Law and Public Policy

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Rep. Susan Brooks Visits New Specialized Pharmacy

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Rep. Susan Brooks (R-IN05) met with pharmacists (cite names as pictured) working in a new controlled substances pharmacy recently opened in Indianapolis by Cordant Health Solutions.

Medicine

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GW School of Medicine and Health Sciences, Wound Repair and Regeneration, Opioid, Opioid use, Chronic Wounds, Wound Healing, Healthcare, Health Care, Emergency Medicine, Geriatric Care, Geriatric Health Care, Pain Managament

New Study Finds Chronic Wound Patients Who Never Receive Opioids Heal Faster

Victoria Shanmugam, M.D., associate professor of medicine at the George Washington University School of Medicine and Health Sciences, published a study in Wound Repair and Regeneration finding that opioid exposure is associated with reduced likelihood of healing in patients with chronic wounds.

Medicine

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Scripps Florida Scientists Create Innovative Drug Design Strategy to Improve Breast Cancer Treatment

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A new study by scientists from the Florida campus of The Scripps Research Institute (TSRI) offers a novel structure-based drug design strategy aimed at altering the basic landscape of this type of breast cancer treatment.

Medicine

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Last-Line Antibiotics Are Failing

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On the occasion of the 9th European Antibiotic Awareness Day, the European Centre for Disease Prevention and Control (ECDC) is releasing its latest EU-wide data on antibiotic resistance and antibiotic consumption.

Science

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Cancer, Pharmacy

National Pharmacogenomics Expert Joins Markey, College of Pharmacy Faculty

The University of Kentucky Markey Cancer Center and UK College of Pharmacy welcome clinical pharmacologist Dr. Jill Kolesar to their respective teams. Kolesar has extensive experience in oncology pharmacogenomics and the implementation of clinical trials, and she will serve several roles at UK with a focus on enhancing the UK Markey Cancer Center's precision medicine initiatives.

Medicine

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Reflux and Ulcer Medications Linked to Kidney Stones and Chronic Kidney Disease

• Individuals who took proton pump inhibitors or histamine receptor-2 blockers for heartburn, acid reflux, or ulcers had elevated risks of developing kidney stones. • In individuals without acute kidney injury, proton pump inhibitors were linked with a higher risk of developing chronic kidney disease or kidney failure compared with histamine receptor-2 blockers. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

Medicine

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Osteoporosis, NYU Dentistry, New York University College of Dentistry, National Institute of Diabetes and Digestive Kidney Diseases, Research Grant

NYU College of Dentistry’s Dr. Nicola Partridge Awarded $1.9 M to Further Osteoporosis Drug Research and Development

The federally funded grant will support bench research aimed at understanding how the protein hormone, parathyroid hormone-a related protein-and a drug analog that mimics the protein called abaloparatide, interact in the surface of a cell in bone and affect bone formation and breakdown.

Science

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antibiotic resisistance, Antibiotics, E. Coli, Bacteria, supercomputering, Drug Discovery, efflux pumps, Proteins, Modeling And Simulation, High Performace Computing

Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance

Supercomputer simulations at the Department of Energy’s Oak Ridge National Laboratory have played a key role in discovering a new class of drug candidates that hold promise to combat antibiotic resistance. In a study led by the University of Oklahoma with ORNL, the University of Tennessee and Saint Louis University, lab experiments were combined with supercomputer modeling to identify molecules that boost antibiotics’ effect on disease-causing bacteria.

Life

Social and Behavioral Sciences

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drug war, Drug Policy, HIV, African Americans, Stigma and Health, incarcerated men

Public Health Researchers Examine How Drug Policy Impacts HIV Vulnerability Among African Americans

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Researchers at the University of Louisville School of Public Health and Information Sciences have developed a tool for framing the relationship between policy, criminal justice practices and HIV-related factors that impact racial disparities.

Medicine

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Purdue Pharma, The University of Texas Health Science Center at Houston (UTHealth), Michael Blackburn, Bruce D. Butler, Drug Development

UTHealth, Purdue Pharma Enter Long-Term Research & Education Alliance

UTHealth and Purdue Pharma L.P. have entered into a specialized alliance to bring academic researchers and drug developers closer together with the common goals of accelerating the development of new drug therapies for patients while advancing the science and providing unique educational experiences for both.

Science

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Controversial Drug Approval Stirs Deep Concerns — and Hope

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In September, the Food and Drug Administration approved Exondys, a controversial treatment for Duchenne muscular dystrophy based on tenuous data from just 12 patients. The cover story in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, explores what the decision could mean for future drugs for Duchenne and other rare diseases.

Medicine

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Saint Louis University, SLUCare, paul hauptman, Heart Failure, Generic Drugs

SLU Research: Wide Variability in Generic Heart Failure Drugs Can Make Them Unaffordable to Uninsured Patients

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New research from Saint Louis University finds that the prices for commonly used generic heart failure drugs varies widely.

Medicine

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Genome, Genome Sequence, Precision Medicine, Precision Medicine Initiative, Governor Brown, CHORI

UCSF Benioff Children’s Hospital Oakland Research Institute and Partners to Receive $1.2 Million Grant from California Initiative to Advance Precision Medicine

A team at the Oakland and San Francisco campuses of UCSF Benioff Children’s Hospitals, UCSF, and UC Berkeley have been awarded $1.2 million by California Initiative to Advance Precision Medicine (CIAPM) to help advance precision medicine in the state.







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