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Medicine

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Opioids

Specialized Pharmacies Satisfy Unmet Security Need for Preventing Pain Medication Misuse

In Colorado and other states, establishing specialized controlled substances pharmacies is proving to be a workable and practical solution to help prevent medication abuse and assure that legitimate pain patients will continue to receive the medication they need.

Science

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Review of Scientific Instruments, Nature Photonics, SLAC National Accelerator Laboratory, spiral light, Light, Molecules, Linac Coherent Light Source, LCLS , X-Ray, xray, Xrays, delta undulator, Chiral, chiral molecules, Agriculture, Agricultural Chemicals And Pathogens, Pharmaceticals, Pharmaceucticals, Drugs, Chirality, Polarization, Polarized Light

Spinning the (X-ray) Light Fantastic

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For the first time, X-ray scientists have access to wavelength-tunable circularly polarized free-electron laser pulses in the range between 280 and 1200 eV. Several types of experiments can benefit from the short and intense pulses.

Medicine

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Diabetes, Insulin, Metabolic Disease, T1D

Case Western Receives $2.5 Million Helmsley Grant for “Smart” Insulin Development

The Leona M. and Harry B. Helmsley Charitable Trust awarded a $2.5 million grant to the Case Western Reserve University School of Medicine to continue research on a new form of insulin for those living with type 1 diabetes (T1D).

Medicine

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Vision, eye, Research, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Eye Disease, eye disease research, eye disease treatment, Blindness, Genomics, Stem Cell, Biology, Imaging, Genetics, Ophthalmology, ophthalmology research, Ophthalmic Imaging, Ophthalmic Treatment, Ophthalmic Drugs

Mount Sinai Establishes Eye and Vision Research Institute

Institute Will Pursue Cutting-Edge Research to Find Treatments and Cures

Medicine

Science

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Charlotte Sumner, nusinersen, Therapy, Johns Hopkins, mice, SMN, FDA, drug, DNA, RNA, Spinal Muscular Atrophy

Experiments in Mice May Help Boost Newly FDA-Approved Therapy for Spinal Muscular Atrophy

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Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy.

Medicine

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Breast Cancer, Breast Cancer Research, repurposing cancer drugs, repurposing drugs

Drug That Improves Blood Flow in Damaged Heart Might Also Fight Breast Cancer

Researchers are looking at a drug once used to improve blood flow in damaged hearts in thousands of patients as a possible treatment option for triple negative breast cancer (TNBC).

Medicine

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Pancreatic Cancer, Yale Cancer Center, Asprin And Cancer

Aspirin Use Found to Lower Risk of Pancreatic Cancer

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The regular use of aspirin lowers the risk for pancreatic cancer by almost 50 percent, a new study in China led by the Yale School of Public Health finds.

Medicine

Science

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Optogenetics, Pharmacology, Biochemistry & Biophysics

Optogenetics Breakthrough: UNC Scientists Expand the Use of Light to Control Protein Activity in Cells

Scientists at the University of North Carolina School of Medicine have developed a method to control proteins inside live cells with the flick of a switch, giving researchers an unprecedented tool for pinpointing the causes of disease using the simplest of tools: light.

Medicine

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Esophageal Cancer, The Cancer Genome Atlas

Comprehensive Study of Esophageal Cancer Reveals Several Molecular Subtypes, Provides New Insight Into Increasingly Prevalent Disease

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A comprehensive analysis of 559 esophageal and gastric cancer samples, collected from patients around the world, suggests the two main types of esophageal cancer differ markedly in their molecular characteristics and should be considered separate diseases.

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Vitamin D Deficiency Increases Risk of Chronic Headache

Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports

Medicine

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dry eye, Gordon Laurie, University Of Virginia, UVA, University of Virginia School of Medicine, drug, Drugs, Treatment, Tears, Cell Biology, Clinical Trial, Licensing, Startups

New Dry Eye Drug Aims to Treat Cause Rather Than Mask Symptoms

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University of Virginia Health System researchers have developed a potential therapeutic treatment for dry eye, with human testing to start in March. The drug differs from other treatments of dry eye in that it aims to treat the cause of dry eye instead of masking the symptoms. About the drug The drug, Lacripep (TM), is a topical eye drop that functions differently from conventional  approaches.

Medicine

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Melanoma, melanoma biology, melanoma biomarkers, Melanoma Metastasis , melanoma pathways, genes, genes and disease, Skin Cancer, Skin Cancer Risk, Drug Discovery And Development, Chemical Compounds, Scleroderma, Gene Transcription

Promising New Drug Stops Spread of Melanoma by 90 Percent

Michigan State University researchers have discovered that a chemical compound, and potential new drug, reduces the spread of melanoma cells by up to 90 percent. The man-made, small-molecule drug compound goes after a gene’s ability to produce RNA molecules and certain proteins in melanoma tumors. This gene activity, or transcription process, causes the disease to spread but the compound can shut it down.

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antidepessant medication

Antidepressant Side Effects Reported More by Patients with Co-Occurring Panic Disorder

Patients who take medication for depression report more side effects if they also suffer from panic disorder, according to a new study led by researchers from the University of Illinois at Chicago published in the Journal of Clinical Psychiatry.

Medicine

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Alzheimer's, Drug Discovery, Jeff Conn, Craig Lindsley, academic drug discovery , Vanderbilt Center for Neuroscience Drug Discovery , William K. Warren Foundation, Schizophrenia, Paul Newhouse, Alzheimer’s Association, Alzheimer’s Drug Discovery Foundation

Investigational New Drug for Alzheimer’s Scheduled for First Study in Humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration (FDA) that testing in humans may proceed for an investigational new drug after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

Medicine

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targeted cancer therapy, Immune Cells, nanoparticle drug delivery

New Technique Uses Immune Cells to Deliver Anti-Cancer Drugs

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Penn State biomedical engineers have created a smart, targeted drug delivery system using immune cells to attack cancers.

Medicine

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pain, IASP, Opioids, opioid abuse, Psychiatry, Psychiatric Evaluation, Psychoactive Drugs, Medical Insurance, Long Term Pain Medications, Pain Medicine, Substance Abuse, substance abuse disorders

Psychiatric Conditions Linked to Increased Risk of Long-Term Opioid Use

A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published by Wolters Kluwer.

Medicine

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Polypharmacy, Geriatrics

A Baby Boomer’s New Year Resolution: Ask Your Doctor About Your Medicines

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A Saint Louis University geriatrician says her patients frequently feel better when she reduces the number of medicines they take. She advocates older adults who take five or more medications talk their doctors annually about triaging their pill boxes.

Medicine

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ASHP, Antibiotic Stewardship , Mentorship, American Society of Health-System Pharmacists, Antibiotic Administration, MQIIP, ASHP Mentored Quality Improvement Impact Program, Debra Goff, Serena Von Ruden, George Karam, St. Francis Hospital, ASHP InterSections, Antibiotic Resistance, The Ohio State University Wexner Medical Center , Pharmacy, Pharmacist, He

Interdisciplinary Teamwork Yields Improved Antibiotic Stewardship

A hospital engaged in a quality improvement program launched by ASHP (American Society of Health-System Pharmacists) has identified weaknesses in existing antibiotic stewardship initiatives and implemented workflow changes that resulted in faster antibiotic administration. St. Francis Hospital in Federal Way, Wash., was recently featured in ASHP’s InterSections, which highlights the hospital’s team approach to improving infection treatment with IV antibiotics.

Medicine

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Moffitt Researchers Use Mathematical Modeling to Explain Evolutionary Phenomenon That Leads to Treatment Resistance

A collaborative team of researchers from Moffitt Cancer Center’s Integrated Mathematical Oncology (IMO) Program, led by Alexander Anderson, Ph.D., and Oxford University’s Department of Computer Science are using mathematical models to explain how bacteria and cancer cells exploit an evolutionary process known as bet-hedging to resist medical intervention.

Medicine

Science

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Cell Signaling, G-Proteins, Pharmacology, Biochemistry & Biophysics, Cancer

Inside the World of Cell Signaling: A G-Protein Breakthrough

Scientists have few good methods for manipulating and investigating G-protein signaling. Now, UNC scientists have developed small proteins to selectively block a certain type of G-protein signaling, creating a unique and powerful tool for studying cell processes that depend on this signaling.







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