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Science

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Adhesion, Biochemistry, Biophysics, Podosome, Arf1, myosin II, Cytoskeleton

Cellular Podiatry

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A study by researchers from the labs of Prof Alexander Bershadsky at the Mechanobiology Institute, Singapore and Prof Gareth E Jones at King’s College London has revealed that a protein known as Arf1 plays a role in podosome formation by regulating the assembly of myosin-II within the cytoskeleton.

Medicine

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TTUHSC El Paso, Propranolol, Brad Bryan, Anticancer Fund, orphan drug designation, orphan drug, Rare Diseases, Soft Tissue Sarcoma, angiosarcoma, Soft Tissue Sarcomas, Angiosarcomas, Texas Tech University Health Sciences Center El Paso, Europe, Eddy Pasquier, Shripad Banavali, Pan Pantziarka

Common Heart Drug Repurposed to Treat Rare Cancer in Europe

A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).

Life

Social and Behavioral Sciences

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Learning, Memory, testing accuracy, Exams, Students, University Students, Eyewitness Testimony, study methods, Brain Activation, Baylor University, Canadian Institutes Of Health Research, University Of Toronto, Rotman Research Institute, Baycrest, Visual Cues, Aging, foreign films

Want to Ace an Exam? Tell a Friend What You Learned

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Students who are given information and tell someone about it immediately recall the details better and longer — a strategy which could be a plus come test time, says a Baylor University researcher.

Medicine

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Jaundice, Bilirubin, unbound bilirubin, total serum bilirubin, preterm babies, Preterm Infants, Premature Baby, Neonate, NICU, Rutgers, Robert Wood Johnson

Rutgers Study Finds Better Way to Test for Jaundice

Researchers at Rutgers Robert Wood Johnson Medical School has found a more accurate test for jaundice, finding that measuring solely for the level of unbound bilirubin rather than total serum bilirubin would more accurately determine the risk of neurotoxicity.

Medicine

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bionic hand reconstruction, myoelectric prosthetic device, treatment protocol, brachial plexus injury, elective amputation, Peripheral Nerve

Candidates for Bionic Hand Reconstruction

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Researchers offer a treatment algorithm, or protocol, for identifying patients with global (flail arm) brachial plexus injuries who are likely to benefit from trading in their insensate and nonfunctional hand for a myoelectric prosthetic device.

Science

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Fossils, Trilobites, cruziana , palaeozoic

Fossils Found Reveal Unseen ‘Footprint’ Maker

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Fossils found in Morocco from the long-extinct group of sea creatures called trilobites, including rarely seen soft-body parts, may be previously unseen animals that left distinctive fossil ‘footprints’ around the ancient supercontinent Gondwana.

Medicine

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Duke Health, Infections Diseases, Mrsa Infections, UV disinfection, UVC , Acinetobacter, C Difficile, vancomycin-resistant Enterococcus faecium, drug-resistant bacteria, drug-resistant organisms, drug-resistant bacterial pathogens, Hospital Safety, Hospital Infection Rates, Infection Control, CDC, CDC Prevention Epicenters Program, Niaid, National Center f

UV Light Can Aid Hospitals’ Fight to Wipe Out Drug-Resistant Superbugs

A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.

Medicine

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Crash Risk, Truck Driver

How Safe Is That Driver Next to You? A Trucker’s Poor Health Could Increase Crash Risk

As commuters shimmy past large, lumbering trucks on the road, they may glance over and wonder, “How safe is that driver next to me?” If the truck driver is in poor health, the answer could be: Not very. Commercial truck drivers with three or more medical conditions double to quadruple their chance for being in a crash than healthier drivers, reports a new study led by investigators at the University of Utah School of Medicine.

Medicine

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Cancer, Melanoma, PD-1 blockade, Skin Cancer, Drug Resistance

Ludwig Study Reveals Why Cancer Cells Spread Within the Body

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Findings uncover an ancient mechanism that makes cancer cells invasive, explains melanoma’s resistance to therapy and opens the door to development of novel cancer therapies

Medicine

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Heart Failure, heart recovery, T-tubules, Biomarker

Biomarker Could Identify Patients with Potential for Recovering From Advanced Heart Failure

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Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure patients who have defied the odds and showed signs of recovery from the disease. Published online in the journal Circulation, the new findings could help clinicians identify the best candidates for cardiac recovery therapies.

Medicine

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Shark, Parkinson's Disease, Steroid, Protein, Nervous System, Lewy Body Dementia

Steroid Originally Discovered in the Dogfish Shark Attacks Parkinson’s-Related Toxin in Animal Model

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A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease. The clustering of this protein, alpha-synuclein (α-synuclein), is the hallmark of Parkinson’s and dementia with Lewy bodies, suggesting a new potential compound for therapeutic research.

Medicine

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Leishmania, persistent infection, Latent Infection, Immune System

Persistent Infection Keeps Immune Memory Sharp, Leading to Long-Term Protection

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Microbes can persist in people for years after an illness, even in people who are healthy and immune to recurrence. Now, researchers have found a clue to this seeming paradox: Persistent microbes are constantly multiplying and being killed, keeping the immune system prepared for any new encounters.

Science

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X-ray science, Materials Science, Advanced Photon Source, Energy Sources, Hydrogen, Defects in materials , Nanoscience, Superconductivity, Synchrotron Radiation, Synchrotron Instruments and Techniques, X-ray Scattering and Detection

For First Time Ever, X-Ray Imaging at Argonne Captures Material Defect Process

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Researchers at Argonne National Laboratory have discovered a new approach to detail the formation of material defects at the atomic scale and in near-real time, an important step that could assist in engineering better and stronger new materials.

Science

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binary star, Aquarius, Milky Way, Astrophysics, Astronomy, Binary Star System, Stars

Notre Dame Astrophysicists Discover Dimming of Binary Star

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A team of University of Notre Dame astrophysicists has observed the unexplained fading of an interacting binary star, one of the first discoveries using the Sarah L. Krizmanich Telescope.

Science

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Materials Science, Energy

Flexible Ferroelectrics Bring Two Material Worlds Together

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Thanks to a new discovery by Argonne National Laboratory in collaboration with researchers at Northwestern University, scientists have pioneered a new class of materials with advanced functionalities that moves the idea of flexible ferroelectrics from the realm of oxymoron into reality.

Medicine

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Best Treatment Option Written in Cancer's Genetic Script

Acute myeloid leukaemia study finds personalised therapy is possible.

Medicine

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Andrew Feinberg, Pancreatic Cancer, Epigenetic, Metastases, Tumor

Potentially Reversible Changes in Gene Control 'Prime' Pancreatic Cancer Cells to Spread

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A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

Science

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Anthropology, acheology, Bering Strait, human settlements, Yukon, Radiocarbon, PLoS ONE, Montreal

The First Humans Arrived in North America a Lot Earlier Than Believed

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Anthropologists at Université de Montréal have dated the oldest human settlement in Canada back 10,000 years.

Medicine

Life

Social and Behavioral Sciences

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Gun Violence in PG-13 Movies Continues to Climb Past R-Rated Films

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The amount of gun violence in top-grossing PG-13 movies, which can be seen by children of all ages, has continued to exceed the gun violence in the biggest box-office R-rated films, a new analysis published in the journal Pediatrics shows.

Science

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Diversification Key to Resilient Fishing Communities

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Fishing communities can survive ― and even thrive ― as fish abundance and market prices shift if they can catch a variety of species and nimbly move from one fishery to the next, a new University of Washington study finds.







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