El estudio se publicó en Genome Medicine y descubrió que posiblemente se puede predecir el futuro de la artritis reumatoide de un paciente al dirigir la atención hacia los billones de bacterias, virus y hongos que habitan en el tracto gastrointestinal, conocidos como microbioma intestinal.
The American College of Rheumatology (ACR) is providing complimentary registration to journalists wishing to write about studies presented at ACR Convergence 2021, the ACR’s annual meeting taking place Nov. 1 – 10.
A textile-based implant containing cartilage derived from stem cells reduced pain and restored hip joint function to baseline levels in a study of dogs with symptoms of moderate osteoarthritis.
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic's Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient's future rheumatoid arthritis prognosis could be possible by zeroing in on the trillions of bacteria, viruses and fungi that inhabit their gastrointestinal tract, known as the gut microbiome. The findings suggest that gut microbes and a patient's outcome of rheumatoid arthritis are connected.
Researchers at Michigan Medicine are creating a hybrid sleep-exercise intervention to mitigate osteoarthritis-related pain.
The newly released Action Briefs now make it easier for employers, insurers, healthcare systems, policy makers, and leaders in other organizations to take specific, practical actions to support their constituents with osteoarthritis, by providing tools and resources to help prevent joint injuries and reduce the pain and disability associated with the disease.
At the AAOS annual meeting, Hospital for Special Surgery (HSS) sports medicine surgeon David Dines, MD, participated in an instructional case lecture on practical solutions in shoulder arthroplasty for patients with substantial shoulder socket bone loss known as glenoid bone deficiency.
Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.
Researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, deliver a biologic drug in response to inflammation.
The United States’ longest-running NIH-sponsored musculoskeletal research center will receive $4M to continue its studies of everything from ligament tears to osteoarthritis
Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.
Researchers at Washington University School of Medicine in St. Louis have found antibodies that protect against specific mosquito-borne viruses that cause arthritis and brain infections. The findings could lead to a universal therapy or vaccine for the viruses.
باحثو مايو يطورون خوارزمية للتنبؤ بنشاط مرض التهاب المفاصل الروماتويدي
妙佑医疗国际(Mayo Clinic) 个体化医学中心和风湿病学科的研究人员开发了首个机器学习算法创举，可以预测患者的类风湿性关节炎疾病活动。该算法可分析血液中的生化代谢物 ― 人体代谢的产物。
Pesquisadores do Centro de Medicina Individualizada e da Divisão Reumatológica da Mayo Clinic desenvolveram um algoritmo de aprendizado pioneiro que pode prever a atividade da artrite reumatoide em um paciente. O algoritmo analisa metabólitos bioquímicos - os produtos do metabolismo corporal - no sangue.
Los investigadores del Centro para Medicina Personalizada y de la División de Reumatología en Mayo Clinic desarrollaron el primer algoritmo de aprendizaje automático capaz de predecir la actividad de la artritis reumatoide en un paciente. El algoritmo analiza en la sangre los metabolitos bioquímicos, que son los productos del metabolismo corporal.
The OAAA will expand and improve equity in access and delivery of evidence-based interventions to prevent and manage symptoms of OA, and strengthen partnerships focused on minimizing impact of the disease.
CorEvitas, LLC, the leading sponsor of registries in autoimmune and inflammatory diseases announces first patient enrollment in a new biospecimen study for patients enrolled in its rheumatology registries. Eligible rheumatology registry patients will contribute biological specimens that will be linked to longitudinal provider reported clinical and patient reported outcomes.
Nanofiber-based treatments stimulate the body to mount its own biological attack on immune disorders.
The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), released three new guidelines for the treatment and management of systemic vasculitis.
Studies by Dr. Geoffrey Westrich and colleagues at HSS have found that the dual mobility prosthesis reduces the risk of dislocation, one of the most common complications after hip replacement surgery.
The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), released three new guidelines for the treatment and management of systemic vasculitis.
The American Medical Association (AMA) House of Delegates passed a resolution developed by the American College of Rheumatology (ACR) to oppose insurance companies providing financial incentives for patients to switch from their prescribed treatment to a payer-preferred treatment.
An international team of researchers, led by UC Davis Health, developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.
For patients with severe arthritis of the ankle, total ankle arthroplasty (TAA) provides better long-term function than ankle arthrodesis (AA), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
New research to be presented this week virtually at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2021 explores the positive and negative effects of lifespan-extending drugs on mitochondrial function and age-related osteoarthritis (OA).
A hand surgeon at Hospital for Special Surgery in New York City performed the first total wrist replacement with an implant he designed. The device, known as KinematX™, received 510(k) clearance from the FDA in 2020.
After a team of researchers showed that a certain enzyme’s presence in cartilage increased significantly in people with osteoarthritis, they targeted it with specially-loaded nanoparticles that stopped the disease’s progression in its tracks.
Dawn Elliott, Blue and Gold Distinguished Professor of Biomedical Engineering at the University of Delaware, has won an $11.8 million grant from the National Institutes of Health to establish the Delaware Center for Musculoskeletal Research -- an NIH-designated Center of Biomedical Research Excellence (COBRE). From tendonitis to osteoarthritis, the center will focus on uncovering what happens at the cellular level when injuries and inflammation occur and will test potential therapeutic interventions.
Tocilizumab, an anti-inflammatory drug used to treat rheumatoid arthritis, improves outcomes in severely ill COVID-19 patients, finds the results of a new trial conducted in hospitals across India — one of the world’s most ethnically diverse countries.
Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
Researchers reporting in ACS’ Nano Letters have developed magnesium-based micromotors propelled by hydrogen bubbles, which improved rheumatoid arthritis symptoms when injected into the joints of rats.
In a study released Feb. 22 in JAMA Internal Medicine researchers found that six 20-minute telephone calls over eight weeks coaching participants on how to get better sleep improved their sleep, pain, and daytime function. The improvements in sleep and daytime function persisted 12 months after treatment. One of the lead investigators who has been researching age and sleeping for 40 years offers great tips on getting better sleep. Just because you are aging, does NOT mean your sleep needs to get worse.
In a statewide study of adults over 60 with osteoarthritis, researchers found that effective treatment for insomnia can be delivered in a few short phone calls.
The 2021 Kappa Delta Young Investigator Award was presented to Lin Han, PhD, for research on the structure and function of cartilage extracellular matrix (ECM) and its impact on tissue regeneration and disease evolution in osteoarthritis (OA).
The 2021 Kappa Delta Elizabeth Winston Lanier Award was presented to Farshid Guilak, PhD and his co-authors, Bradley T. Estes, PhD, and Franklin T. Moutos, PhD, for their research and development of technology to grow bioartificial cartilage using a patient’s own donor cells and seeding them on a novel scaffold that can be molded to match the shape of a patient’s joint.
The American College of Rheumatology (ACR) has released its COVID-19 Vaccine Clinical Guidance Summary that provides an official recommendation to vaccinate rheumatology patients with musculoskeletal, inflammatory and autoimmune diseases. Important considerations and caveats on how to approach vaccination are included for patients with high disease activity and/or those taking immunosuppressant treatments.
In a new study, scientists have discovered the cellular pathway that leads to osteoarthritis and have identified a commonly used anti-depressant — paroxetine — that inhibits this pathway.
Robotic-assisted knee replacement allows for optimal alignment and positioning of the knee implant, as well as optimal ligament balancing. This is critically important for the best outcome and long-term success of the surgery, according to Geoffrey Westrich, MD, at Hospital for Special Surgery. Such precision could potentially lead to a longer-lasting knee replacement.
Researchers at Washington University School of Medicine in St. Louis have engineered cartilage cells to release an anti-inflammatory drug in response to stresses such cells undergo when they are compressed during weight bearing and movement.
Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm.
In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain
For patients undergoing surgery for a hip fracture, there are still unknowns regarding the return to pre-facture level of function, specifically in regard to driving and mobility. However, a new article published in the January issue of the Journal of the American Academy of Orthopaedic Surgeons® (JAAOS®) further quantifies these outcomes. The study authors found that patients can expect to regain full functionality within two to three years after hip fracture surgery. The study also looked at the long-term psychosocial limitations of patients compared to peer groups and concluded that socialization may aid in recovery.
The cumulative incidence of hip dislocation following total hip replacement is about 50 percent higher than suggested by simple analysis of hospital data, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
A pioneering study carried out among patients in remission from Rheumatoid Arthritis has determined that they display significantly higher temperatures than healthy individuals.
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