Scientists at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.
Suzanne Olbricht, MD, Chief of Dermatology at Beth Israel Deaconess Medical Center, shares tips for avoiding sunburns.
A pilot study led by researchers from Tufts University and conducted at the Somerville Council on Aging in Somerville, Mass., translated for the first time the physical activity benefits of the Lifestyle Interventions and Independence for Elders study in a community setting.
New study reveals that a male fruit fly’s decision to court or ignore a female stems from the convergence of motivation, perception and chance that affects the balance of excitatory versus inhibitory signals in the brain to influence decision making. Findings may yield insights about addiction disorders, depression.
In a new study, a team led by clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) surveyed family members and patients with recent ICU experiences about their willingness to speak up about care concerns to medical providers.
A new study out of Beth Israel Deaconess Medical Center reveals that the preventability of readmissions changes over time: readmissions within the first week after discharge are often preventable by the hospital, whereas readmissions later are often related to patients’ difficultly accessing outpatient clinics.
Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology The variations explain why the human protein is more precise and more selective than mammalian forms of the protein and why it targets certain types of DNA but ignores others The findings can inform the design of more precisely targeted immune therapies against cancer and a range of immune-mediated diseases
The Bertarelli Foundation has announced that it is redoubling its investment in this area of research, with a gift of $6.35 million to Harvard Medical School (HMS) to build on the previous successes of the Bertarelli Program in Translational Neuroscience and Neuroengineering.
Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65
Barbara Kahn, MD, Vice Chair for Research Strategy in the Department of Medicine at Beth Israel Deaconess Medical Center (BIDMC), will receive the 2019 FASEB Excellence in Science Award.
Study findings from a team of scientists led by George C. Tsokos, MD, Chief of the Division of Rheumatology at BIDMC, overturn conventional wisdom about kidney disease.
Research reveals dramatic geographic differences in end-of-life care spending across the United States. Spending variations stemmed from doctors’ beliefs about end-of-life care and style of practice and from availability of health care services. Patient beliefs and preferences did not contribute to spending differences. Health care spending in the last month of life for patients with end-stage cancer in some regions is twice as high as that in other regions. The additional spending is wasteful and possibly harmful.
Providing free fruits and vegetables and limiting sugary drinks in schools could have positive health effects in both the short- and long-term, finds a new Food-PRICE study led by researchers from the Friedman School of Nutrition Science and Policy at Tufts University.
In a new study, published July 6 in The Lancet, a team of researchers led by Beth Israel Deaconess Medical Center's Dan H. Barouch, MD, PhD, in collaboration with Janssen Vaccines & Prevention and other partners, evaluated a series of preventative HIV vaccine regimens in uninfected human volunteers in five countries. In a similarly designed study, Barouch and colleagues tested the same vaccine for its ability to protect rhesus monkeys challenged with an HIV-like virus from infection. The findings showed the vaccines induced robust and comparable immune responses in humans and monkeys and protected monkeys against acquisition of infection.
Researchers at Beth Israel Deaconess Medical Center have found that consuming a broth rich in umami—or savory taste—can cause subtle changes in the brain that promote healthy eating behaviors and food choices, especially in women at risk of obesity.
A “smart” bandage is designed to monitor the condition of chronic wounds and deliver drug treatments to improve chances of healing. While the bandages remain to be assessed in a clinical context, the research is aimed at transforming bandaging from a passive to an active treatment paradigm.
In this study, BIDMC researchers developed a means of tracking the activity of the far-reaching ends of retinal neurons (called boutons) as they deliver visual information to the thalamus, a brain region involved in image processing.
Olin Receives $400,000 Gift for Exploring Innovation in Engineering Education
If you’ve ever had a migraine, you know it’s different from a typical tension headache. Check out these tips from neurologist Sait Ashina, MD, for avoiding common migraine triggers.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
A new study finds that a mysterious component of the inner ear acts as a pressure-relief valve, formed by a thin barrier of cellular projections that opens and closes to regulate the release of inner ear fluid.
For the first time, scientists have directly visualized real-time structural changes in the surface protein of the influenza virus that may help the virus fuse with and enter target cells before hijacking them. Single molecules of the protein were found to stretch toward target cells, then refold and try again 5 to 10 times per second. The discovery may help develop more effective vaccines and better understand other viruses, including Ebola, HIV, and SARS.
In a new pilot study, a team led by researchers from Tufts University School of Medicine conducted the first full comparison of gonococcal gene expression and regulation in both men and women, identifying gender-specific signatures in infection and in antibiotic resistance genes.
Microbiologist Aimee Shen at Tufts University School of Medicine is one of 12 new recipients nationwide of the Burroughs Wellcome Fund 2018 Investigators in the Pathogenesis of Infectious Disease (PATH) award for her research on Clostridium difficile.
Olin and Emerson Colleges have joined forces to produce a groundbreaking one-day event—Remaking Education—designed to raise awareness of the need for change in education, and to inspire action among leaders in education, business, and the non-profit world. T
The 2018 Warren Alpert Foundation Prizehas been awarded to five scientists for transformative discoveries in the fields of genetics, physiology, pulmonology and pharmacology that have led to the development of life-altering precision-targeted treatments for the devastating multiorgan disease cystic fibrosis (CF).
Harvard Medical School’s Media Fellowship program, now entering its 21st year, is accepting applications for its fall 2018 session.
Olin College announces nine new faculty will join the College over the next two years.
Olin College and Aerodyne plan to install eight to twelve ARISense instruments around East Boston, at a fraction of the cost of a single EPA monitoring site.
Sara Hendren, an artist, designer and researcher-in-residence at Olin College has been awarded an Artist Fellowship in non-fiction writing from the Massachusetts Cultural Council.
A new MIT study has named Olin College of Engineering, along with MIT, as the top leaders in engineering education globally.
Brooklyn-based artist and researcher Mimi Onuoha has been named the first “Creative-in-Reference” at Olin College, a position established as part of a multi-step $900,000 grant from the Andrew W. Mellon Foundation designed to better integrate the arts and humanities within a STEM education.
The Carey Institute for Global Good has named Sara Hendren a Logan Nonfiction Program Fellow. Hendren is a designer and researcher in residence at Olin College and is writing a book about the unexpected places where disability is at the heart of design, to be published by Riverhead Books
A group of national leaders in quality and safety, led by researchers at Beth Israel Deaconess Medical Center (BIDMC), has developed a consensus statement – a document developed by an independent panel of experts about a particular issue – intended to embrace an expanded definition of patient harm that includes non-physical harm, with the goal of improving the practice of respect across the continuum of care.
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment.
BIDMC researchers led a retrospective analysis of four randomized clinical trials focused on the effects of DAA therapies in patients with HCV-associated liver failure and developed a new means of predicting improvement in liver function in response to DAA treatment.
Like everyone, people with type 2 diabetes and obesity suffer from depression and anxiety, but even more so. Researchers at Joslin Diabetes Center now have demonstrated a surprising potential contributor to these negative feelings – and that is the bacteria in the gut or gut microbiome, as it is known.
A new Food-PRICE study finds persistent nutritional disparities within the food choices of those receiving assistance under the Supplemental Nutrition Assistance Program (SNAP) compared to those not receiving SNAP assistance.
Six Babson businesses have been chosen to join the 2018 MassChallenge Boston Cohort. Cleancult, DetraPel, Dondoctor, Magnomer, Unruly Studios, and Cellular Preservation Technologies are a part of the 128 early-stage startups recognized for having the potential to create widespread impact across industries.
A new study led by public health researchers at Tufts University School of Medicine reports significant food insecurity for adults on probation in Rhode Island. Nearly three-quarters of the participants experienced food insecurity over a 30-day period, with almost half having very low food security.
Changes in diet have been proposed as a way to reduce carbon emissions from the food system. A new study provides the latest and most comprehensive estimate of greenhouse gas emissions generated by U.S. consumer food purchases, and assesses how those choices could affect diet and climate change.
Research in mice shows that a protein made by the stem cells that give rise to neurons, but not by neurons themselves, is key to brain cells’ ability to migrate during development and assume their proper positions. This primordial protein acts by clinging onto thousands of sites in the genome, affecting the activity of multiple genes that regulate brain development. The findings could yield valuable clues for a variety of neurodevelopmental disorders.
BCERC, widely considered the world’s premier conference for entrepreneurial research, was established in 1981 to provide a dynamic venue where academics and real-world practitioners link theory and practice, and to encourage and increase quality research in entrepreneurship.
Managing type 1diabetes during the first two decades of life is challenging. Insulin requirements change along with the stages of life --- childhood, puberty, young adulthood, and beyond. But a 20-year longitudinal study conducted by researchers from Joslin Diabetes Center and Harvard Medical School identifies clear predictors of rising A1c levels in young persons, as well as ways to improve glycemic control in this population.
Eight million largely preventable deaths from treatable diseases cost $6 trillion in lost economic welfare in low- and middle-income countries in 2015. If current conditions persist, low- and middle-income countries could lose collectively $11 trillion in gross domestic product by 2030, or 2.6 percent of total GDP in low-income countries. New analysis believed to be first to quantify global economic toll due to inadequate access to high-quality medical care. Findings stem from analysis of diseases in 130 low- and middle-income countries that are treatable with approaches commonly available in higher-income settings.
Premenopausal women with hormone receptor-positive, HER2-negative breast cancer and a high risk of recurrence who are treated with an aromatase inhibitor plus ovarian function suppression may gain 10 to 15 percent improvement in freedom from distant recurrence at eight years, according to a new clinical trial analysis reported at the annual meeting of the American Society of Clinical Oncology.
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests.
Babson College recognized Lauren Beitelspacher and Anirudh Dhebar as faculty of the year at Commencement ceremonies of May 19, 2018. Beitelspacher of the Marketing Division was named undergraduate Professor of the Year and Dhebar of the Marketing Division won the Thomas Kennedy Award for Professor of the Year at the graduate level.
Tufts University School of Dental Medicine is celebrating 150 years of comprehensive dental education, pioneering research, and a commitment to serving patients and communities. The anniversary will culminate in a gala at the Museum of Science, Boston on September 28.
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