Feature Channels: Cell Biology

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Released: 4-Nov-2023 11:45 AM EDT
Could Magnetic Cell Delivery Transform the Future of Cornea Transplant Surgery?
American Academy of Ophthalmology (AAO)

An investigational treatment shows promise as a non-surgical option for corneal edema.

Newswise: UC Santa Barbara researchers can now visualize osmotic pressure in living tissue
Released: 3-Nov-2023 6:05 PM EDT
UC Santa Barbara researchers can now visualize osmotic pressure in living tissue
University of California, Santa Barbara

In order to survive, organisms must control the pressure inside them, from the single-cell level to tissues and organs. Measuring these pressures in living cells and tissues in physiological conditions is a challenge.

Newswise: Some Benefits of Exercise Stem from the Immune System
1-Nov-2023 8:00 PM EDT
Some Benefits of Exercise Stem from the Immune System
Harvard Medical School

Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.

Released: 3-Nov-2023 12:05 PM EDT
Neutralizing antibodies that target resistant bacteria
German Center for Infection Research (Deutsches Zentrum für Infektionsforschung - DZIF)

Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly feared. Researchers at the German Center for Infection Research (DZIF), the University Hospital Cologne, the Helmholtz Centre for Infection Research in Braunschweig and the University Medical Center Hamburg-Eppendorf have now discovered antibodies that could lead to a highly potent treatment option of acute and chronic infections with P. aeruginosa. The study was published in the prestigious scientific journal Cell.

Newswise: Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
Released: 2-Nov-2023 9:05 PM EDT
Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
Stockholm University

An international team of scientists led by researchers from the Department of Molecular Biosciences, The Wenner-Gren Institute, SciLifeLab, Stockholm University has published in PLoS Pathogens the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host.

Released: 2-Nov-2023 8:05 PM EDT
Rakuten Medical to Present at 2023 Jefferies London Healthcare Conference on November 14
Rakuten Medical, Inc.

Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell targeting therapies based on its proprietary Alluminox™ platform, today announced that the Company will present at the 14th Annual Jefferies London Healthcare Conference being held in London, UK, on November 14-16, 2023.

Newswise: FSU researchers capture high-resolution images of magnesium ions interacting with CRISPR gene-editing enzyme
Released: 2-Nov-2023 4:05 PM EDT
FSU researchers capture high-resolution images of magnesium ions interacting with CRISPR gene-editing enzyme
Florida State University

In research published in Nature Catalysis, scientists at Florida State University produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 enzyme while it cut strands of DNA, providing clear evidence that magnesium plays a role in both chemical bond breakage and near-simultaneous DNA cutting.

Released: 2-Nov-2023 10:05 AM EDT
Metabolite tells cells whether to repair DNA
Michigan Medicine - University of Michigan

Findings from researchers at the University of Michigan Health Rogel Cancer Center, published in Cancer Discovery, show how a specific nucleotide metabolite called GTP controls responses to radiation and chemotherapy in an unexpected way.

Newswise: 2 Markey cancer researchers win V Foundation awards
Released: 1-Nov-2023 1:05 PM EDT
2 Markey cancer researchers win V Foundation awards
University of Kentucky

University of Kentucky Markey Cancer Center researchers Ka-wing Fong, Ph.D., and Eric Rellinger, M.D., were named V Scholars by the V Foundation for Cancer Research. They will each receive $600,000 to fund their individual cancer research projects over three years.

Newswise: Scientists reveal structures of neurotransmitter transporter
30-Oct-2023 1:05 PM EDT
Scientists reveal structures of neurotransmitter transporter
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital determined structures of a transporter protein involved in the movement of neurochemicals such as serotonin and dopamine, unearthing multiple mechanisms that can guide drug development.

   
Newswise: Combining cell types may lead to improved cardiac cell therapy following heart attack
Released: 31-Oct-2023 1:05 PM EDT
Combining cell types may lead to improved cardiac cell therapy following heart attack
University of Wisconsin–Madison

Researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.The study, published in Circulation — which addresses major challenges of using heart muscle cells, called cardiomyocytes, grown from stem cells — takes a crucial step toward future clinical applications.

Newswise: Intestinal bacteria metabolite promotes capture of antigens by dendritic cells
Released: 30-Oct-2023 11:05 AM EDT
Intestinal bacteria metabolite promotes capture of antigens by dendritic cells
Okayama University

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable “arms” called dendrites

Newswise: New antibody could target breast cancers
Released: 30-Oct-2023 11:05 AM EDT
New antibody could target breast cancers
Cold Spring Harbor Laboratory

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

Newswise: Possible cause of male infertility
Released: 27-Oct-2023 5:05 PM EDT
Possible cause of male infertility
Universitätsklinikum Bonn

Mature spermatozoa are characterized by an head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit "Life & Health" at the University of Bonn have found that a loss of the structural protein ACTL7B blocks spermatogenesis in male mice.

Released: 27-Oct-2023 5:05 PM EDT
Hidden way for us to feel touch uncovered by Imperial researchers
Imperial College London

Previously, touch was thought to be detected only by nerve endings present within the skin and surrounding hair follicles.

Released: 27-Oct-2023 10:05 AM EDT
Protein root discovery seals future of climate proof plants
University of Nottingham

Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers

26-Oct-2023 5:05 PM EDT
Find-and-Replace Genome Editing with CRISPR: A Promising Therapeutic Strategy
Bar-Ilan University

A novel replacement strategy termed GE x HDR 2.0: Find and Replace, developed by researchers from Bar-Ilan University and described in published today in Nature Communications, combines CRISPR-Cas9-mediated genome editing with recombinant adeno-associated serotype 6 (rAAV6) DNA donor vectors to precisely replace the RAG2 coding sequence while preserving regulatory elements.

Released: 26-Oct-2023 11:05 AM EDT
UC Irvine study exposes risks of direct-to-consumer stem cell, exosome COVID-19 therapy ads
University of California, Irvine

Irvine, Calif., Oct. 26, 2023 — A study from the University of California, Irvine has revealed that in 2022, 38 North American businesses used direct-to-consumer advertising to promote unproven stem cell interventions and exosome products as purported treatments and preventatives for COVID-19. Collectively, these organizations operated or facilitated access to 60 clinics – with 24 in the U.

Released: 26-Oct-2023 10:05 AM EDT
Machine can quickly produce needed cells for cancer treatment
Washington State University

New WSU bioreactor rapidly grows cancer-killing cells for immunotherapy

Newswise: How mosquito-controlling bacteria might also enhance insect fertility
17-Oct-2023 4:05 PM EDT
How mosquito-controlling bacteria might also enhance insect fertility
PLOS

Biological mechanisms found in fruit flies could inform efforts against disease-spreading mosquitos.

Released: 24-Oct-2023 12:05 PM EDT
How to slow the spread of deadly ‘superbugs’
University of Technology, Sydney

Harnessing new advances in genomic surveillance technology could help detect the rise of deadly ‘superbugs’

Released: 23-Oct-2023 6:05 PM EDT
Researchers identify ‘switch’ to activate cancer cell death
UC Davis Health

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

Newswise: Study reveals how estrogen exerts its anti-diabetic effects
Released: 23-Oct-2023 1:05 PM EDT
Study reveals how estrogen exerts its anti-diabetic effects
UT Southwestern Medical Center

The quintessential female sex hormone estrogen stimulates cells that line blood vessels to deliver insulin to muscles, lowering blood sugar and protecting against Type 2 diabetes, UT Southwestern Medical Center researchers report. The findings, published in Nature Communications, could eventually lead to new therapies for Type 2 diabetes, a disease that affects hundreds of millions of people around the globe and continues to grow more prevalent.

Newswise: Moving muscle fibers with magnets “programs” how they align within tissue
Released: 20-Oct-2023 6:05 PM EDT
Moving muscle fibers with magnets “programs” how they align within tissue
Cell Press

Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue, Massachusetts Institute of Technology (MIT) and Boston University investigators report October 20 in the journal Device.

   
Newswise: Novel dynamic imaging technology captures the body’s immune response to COVID-19 infection
Released: 19-Oct-2023 2:05 PM EDT
Novel dynamic imaging technology captures the body’s immune response to COVID-19 infection
UC Davis Health

A UC Davis study shows the first-in-human imaging of the body’s CD8 T cell immune response to COVID-19 infection in recovering patients.

Released: 19-Oct-2023 11:05 AM EDT
Physical theory improves protein folding prediction
University of Tokyo

New protein folding models could lead to new medicines and industrial processes

16-Oct-2023 6:05 AM EDT
New ‘Subway Map’ of Lyme Disease Pathways Identifies Potential New Treatment Targets
Tufts University

Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or “subway map” of key metabolic activities of the bacterium that causes Lyme disease.

   
Newswise: NUS scientists develop innovative magnetic gel that heals diabetic wounds three times faster
Released: 19-Oct-2023 8:05 AM EDT
NUS scientists develop innovative magnetic gel that heals diabetic wounds three times faster
National University of Singapore (NUS)

A team of researchers from the National University of Singapore has engineered an innovative magnetic wound-healing gel that promises to heal diabetic wounds three times faster, reduce the rates of recurrence, and in turn, lower the incidents of limb amputations. The innovative magnetic hydrogel, which contains skin cells for healing as well as magnetic particles, takes a comprehensive ‘all-in-one’ approach to wound healing, accelerating the process on several fronts. To maximise therapeutic results, a wireless external magnetic device is used to activate skin cells and accelerate the wound healing process. A patent has been filed for this innovation.

Newswise: Therapeutic nanocarriers reduce lung inflammation in mice
Released: 19-Oct-2023 3:20 AM EDT
Therapeutic nanocarriers reduce lung inflammation in mice
National Institute of Biomedical Imaging and Bioengineering

There is no cure or FDA-approved therapy for acute respiratory distress syndrome, which has a high rate of mortality. Inflammation plays a major role in developing ARDS. Researchers at Ohio State University developed therapeutic nanocarriers using mice skin cells, which reduced inflammation in their lungs.

   
Newswise: Converting brain immune cells into neurons helps mice recover after stroke
Released: 18-Oct-2023 6:05 PM EDT
Converting brain immune cells into neurons helps mice recover after stroke
Kyushu University

Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice. These findings, published on October 10 in PNAS, suggest that replenishing neurons from immune cells could be a promising avenue for treating stroke in humans.

   
Released: 18-Oct-2023 10:05 AM EDT
Revealing structural secrets of a key cancer protein
Ohio State University

Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.

Released: 17-Oct-2023 5:05 PM EDT
Multi-drug resistant strain of E.coli battles bacteria in healthy gut
University of Birmingham

Different strains of E.coli can outcompete one another to take over the gut, a new study reveals.

Newswise: New Cancer Therapy Target Stops Tumor Cells From Sharing Resources
Released: 17-Oct-2023 9:00 AM EDT
New Cancer Therapy Target Stops Tumor Cells From Sharing Resources
University of California San Diego

Researchers at University of California San Diego have discovered a process in which liver cells share molecules in order to multiply under conditions that would ordinarily suppress cell proliferation. They also found evidence that this process occurs in various types of cancer cells.

Newswise: Broken mitochondria are guilty of obesity
Released: 17-Oct-2023 7:05 AM EDT
Broken mitochondria are guilty of obesity
Scientific Project Lomonosov

Scientists from Immanuel Kant Baltic Federal University on the base of literary sources have described in detail the connection between intracellular processes in mitochondria and metabolic disorders in human’s organism that lead to obesity and cardiovascular diseases.

Released: 16-Oct-2023 12:05 PM EDT
Novel enzyme family could provide insights into bacterial pathogenicity
Tokyo University of Science

Researchers discover a new family of Gram-negative bacterial enzymes related to infection capability

Released: 16-Oct-2023 11:05 AM EDT
Moffitt Research Finds Non-Small Cell Lung Cancer Drug Lorlatinib Targets Additional Protein
Moffitt Cancer Center

In a new study published in Cell Chemical Biology, Moffitt Cancer Center researchers demonstrate this, showing that the ROS1 inhibitor lorlatinib has activity against an additional protein called PYK2. The team also reveals the mechanisms of this inhibition.

Released: 16-Oct-2023 11:05 AM EDT
FASEB Partners with Wiley and Cadmore to Launch FASEB Conferences On-Demand
Federation of American Societies for Experimental Biology (FASEB)

FASEB Conferences On-Demand will ensure that biological and biomedical scientists can stay up to date on the latest advances—wherever and whenever.

Newswise: Directing vaccines to dendritic cells
Released: 16-Oct-2023 11:05 AM EDT
Directing vaccines to dendritic cells
National Institute of Biomedical Imaging and Bioengineering

Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen.

Newswise: Brain tumor treatment by targeting TUG1, a gene that controls replication stress
Released: 12-Oct-2023 6:05 PM EDT
Brain tumor treatment by targeting TUG1, a gene that controls replication stress
Nagoya University

A new study has unravelled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.

Newswise: Engineered bacteria paint targets on tumors for cancer-killing T cells to see
12-Oct-2023 10:05 AM EDT
Engineered bacteria paint targets on tumors for cancer-killing T cells to see
Columbia University School of Engineering and Applied Science

Synthetic biologists at Columbia Engineering report today a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.

   
Newswise: More U.S. Young Women Diagnosed with Lung Cancer at a Higher Rate Than Young Men, New Report Shows; Increase Extends to Older Women
10-Oct-2023 2:05 PM EDT
More U.S. Young Women Diagnosed with Lung Cancer at a Higher Rate Than Young Men, New Report Shows; Increase Extends to Older Women
American Cancer Society (ACS)

Reversing historical patterns, new findings led by researchers at the American Cancer Society show higher lung cancer incidence in women than in men has not only continued in adults younger than 50 years, but now extends to women 50 to 54 years of age in the United States. The findings are published today in the Journal of the American Medical Association (JAMA) Oncology.

Newswise: Omega watch: Researchers develop new blood test for measuring levels of critical omega-3 fatty acids
Released: 12-Oct-2023 10:05 AM EDT
Omega watch: Researchers develop new blood test for measuring levels of critical omega-3 fatty acids
McMaster University

Researchers at McMaster and the University of Guelph have discovered a convenient new way to track levels of omega-3 fatty acids in the bloodstream, making it much easier to access information that is critical to cardiovascular and cognitive health, but which has previously been challenging to gather. While the human body can generate most of the fats it needs, it cannot produce adequate levels of omega-3 fatty acids and must obtain them from dietary sources. Two key omega-3 fatty acids, called EPA (eicosatetraenoic acid), and DHA (docosahexaenoic acid), can be derived only from certain sources, such as fish, seafood, enriched foods, and supplements, but measuring how much gets into the blood has been both difficult and invasive.

Released: 12-Oct-2023 9:05 AM EDT
Association for Molecular Pathology Publishes Best Practice Recommendations for Liquid Biopsy Assay Validations
Association for Molecular Pathology

The Association for Molecular Pathology has published best practice recommendations for validating and reporting clinical circulating tumor DNA (ctDNA) or liquid biopsy assays and their related scientific publications.

Newswise: Newsmakers: Basic Research Findings by Johns Hopkins Scientists Focus on Gene Sequencing, Hearing Loss and a Brain Disorder
Released: 11-Oct-2023 11:05 PM EDT
Newsmakers: Basic Research Findings by Johns Hopkins Scientists Focus on Gene Sequencing, Hearing Loss and a Brain Disorder
Johns Hopkins Medicine

Basic Research Findings by Johns Hopkins Scientists Focus on Gene Sequencing, Hearing Loss and a Brain Disorder

Released: 11-Oct-2023 3:25 PM EDT
Israel Cancer Research Fund and Cancer Research Institute Announce Co-Funding of a Project Grant
Cancer Research Institute

Michael Berger, PhD, has been awarded a grant by The Israel Cancer Research Fund (ICRF) and the Cancer Research Institute (CRI).

Released: 11-Oct-2023 3:05 PM EDT
New NCI-Funded Clinical Trial Will Test Innovative Ways To Preserving Muscle Mass Among Patients with Metastatic Prostate Cancer
University of Utah Health

Investigators have been awarded a grant to find a better way to protect muscle mass in patients. Muscle mass plays a critical role in quality of life and cancer survival.

Released: 11-Oct-2023 3:00 PM EDT
MD Anderson hosts 2023 Leading Edge of Cancer Research Symposium
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center will host its annual Leading Edge of Cancer Research Symposium Nov. 16-17, 2023, featuring presentations and discussions on genomics, immunity and inflammation, computational approaches for spatial biology, and emerging technologies that are driving the next wave of cancer breakthroughs.

Newswise: HPV Discovery Yields Breakthrough in Understanding Protein Activity
Released: 11-Oct-2023 2:05 PM EDT
HPV Discovery Yields Breakthrough in Understanding Protein Activity
Yale Cancer Center/Smilow Cancer Hospital

A new study led by Yale scientists shows that the activity of a portion of a human papillomavirus (HPV) protein does not depend on its amino acid sequence or composition.



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