Broad-spectrum antiviral candidate targets dengue and SARS-CoV-2
Hokkaido UniversityA broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.
A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.
In study after study, the psychoactive drug ketamine has given profound and fast relief to many people suffering from severe depression.
New research reveals that the nation’s most widely prescribed type of sedative may be less effective than clinicians and scientists have been led to believe, based on publications in medical journals.
A first-of-its kind hormone replacement therapy that more closely replicates the natural circadian and ultradian rhythms of our hormones has shown to improve symptoms in patients with adrenal conditions. Results from the University of Bristol-led clinical trial are published today [20 October] in the Journal of Internal Medicine.
In a first-of-its-kind study, researchers from the University of California, Irvine have discovered an extraordinary surge in the utilization of weight loss-associated GLP-1 receptor agonists, a class of medications commonly used in the treatment of Type 2 diabetes and obesity, that is poised to accelerate, based on emerging clinical evidence.
Scientists have showed that medicine on the base of vitamin B6 can be used for treatment of post-COVID asthenia – condition when patients complain of rapid fatigability, problems with memory and sleep. Taking of this product enabled 35% patients to improve memory, 40% patients began to sleep well, 42% of people began to get tired more slowly. Besides this taking this medicine enabled patients to experience physical activity easier. Results of the research are published in Magazine of Infectology.
Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or “subway map” of key metabolic activities of the bacterium that causes Lyme disease.
Artificial intelligence is being harnessed by some scientists to predict which molecules could treat illnesses. Researchers reporting in ACS Central Science have used one such deep learning algorithm, and found that an antimalarial drug could treat osteoporosis.
Ten63 Therapeutics, a company combining generative AI and physics-based models to develop first- and best-in-class therapeutics with an internal pipeline focused on oncology, is pleased to announce its partnership with newly unveiled cancer-focused venture fund, Yosemite.
A UNLV-led team studied potentially fatal, diarrhea-causing Shigella bacteria, and demonstrated a possible way to prevent it from causing disease.
For people with expensive prescription drugs, switching plans could save them thousands of dollars in copays. And a simple tool can help people easily compare out-of-pockets expenses for anyone with a Medicare Part D prescription plan.
In a new study published in Cell Chemical Biology, Moffitt Cancer Center researchers demonstrate this, showing that the ROS1 inhibitor lorlatinib has activity against an additional protein called PYK2. The team also reveals the mechanisms of this inhibition.
Ochsner Health is proud to receive a 2023 Vizient Pharmacy Vision Award. Ochsner is recognized for Excellence in Innovation, which honors teams who have implemented novel approaches to complex patient care in conjunction with other departments.
Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen.
Combining a common chemotherapy drug with an experimental nanotechnology allowed the drug to cross the blood-brain barrier and increased the survival rate in a mouse model of glioblastoma up to 50%, a team led by researchers from UT Southwestern Medical Center and UT Dallas found.
Daniel Herranz Benito, PhD, PharmD, resident researcher at Rutgers Cancer Institute of New Jersey and RWJBarnabas Health, the state’s leading cancer program and only NCI-designated Comprehensive Cancer Center and assistant professor of pharmacology at Rutgers Robert Wood Johnson Medical School, has received $800,000 from the V Foundation for Cancer Research, a premier cancer research charity, to support his research on acute lymphoblastic leukemia (ALL).
Biochemists from RUDN University described how to prevent cancer cells from becoming resistant to chemotherapy drugs. Having determined the resistance mechanism, biochemists selected a drug that can slow down it.
A guide to vaccines that adults - especially older adults and those with underlying health issues - should get to avoid serious illness this fall and winter, and beyond.
Scientists from the National University of Singapore have developed an innovative catalyst that achieves a significantly lower carbon footprint, paving the way for greener chemical and pharmaceutical manufacturing processes.
Top Italian Scientists join the discussion of AI and Machine Learning presented by the Sbarro Health Research Organization (SHRO) in collaboration with the National Italian American Foundation (NIA) this weekend at the annual NIAF convention and gala.
Researchers at the Icahn School of Medicine at Mount Sinai and the University of California San Diego have been awarded an $8.5 million grant to create a data integration hub aimed at accelerating novel therapeutics and cures for diseases within initiatives supported by the National Institutes of Health (NIH) Common Fund.
While solutions for addressing the opioid crisis often involve either beefing up law enforcement or widening the scope of health services, West Virginia University researchers said they believe the best approach is a synergistic mix of both.
SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long?
Although several medications are approved to treat attention-deficit/hyperactivity disorder (ADHD), some individuals experience limited benefits from the drugs or develop side effects from their use.
A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.
A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found. In mouse models of melanoma, bladder cancer, leukemia and colon cancer, the drug slows the growth of tumors, extends lifespan and boosts the efficacy of immunotherapy.
These drugs are not the be-all and end-all to weight-loss therapy, wrote Dr. Michael Schwartz in a commentary published Oct. 2 in The Journal of Clinical Investigation. His co-author was Sophie Yang Gou, a postdoctoral fellow in Schwartz’s lab at the University of Washington School of Medicine. Many experts seem to be saying “OK, we’ve fixed this problem. We’re done,” noted Schwartz, who co-directs the UW Medicine Diabetes Institute. That is simply not the case, he said.
UT Southwestern Medical Center has been recognized as part of the prestigious American Medical Association 2023 Joy in Medicine Program, underscoring the nationally ranked academic medical center’s commitment to cultivating a culture of wellness, resilience, and professional fulfillment among its health care professionals.
RUDN University chemists and colleagues from Belarus obtained derivatives of the natural polymer chitosan, which exceeded existing antibiotics in antibacterial activity. Moreover, the new substances are non-toxic, and the production method is safe.
One treatment each of two psychedelic drugs lowered depression and anxiety and improved cognitive functioning in a sample of U.S. special operations forces veterans who sought care at a clinic in Mexico, according to a new analysis of the participants’ charts.
If it’s autumn, then it must be influenza season, which means it’s time to consider flu shots for your family.
A new compound developed at the University of Illinois Chicago potentially could offer an alternative to injections for the millions of people who suffer from an eye condition that causes blindness
A Special Issue of SLAS Discovery, Emerging Drug Discovery Ecosystems, is now available.
UVA Health researchers have developed a powerful new tool to understand how medications affect men and women differently, and that will help lead to safer, more effective drugs in the future.
Researchers in the Department of Radiation Oncology at the University of Maryland School of Medicine (UMSOM) presented significant findings in two studies featured today at the American Society for Radiation Oncology (ASTRO) annual meeting in San Diego.
No fewer than 28 immunologists have received the Nobel Prize since 1901, highlighting the importance of immunology to health
Cedars-Sinai investigators have joined with colleagues from seven regenerative medicine institutes in the Los Angeles region to form a new consortium that will share resources and maximize the impact of funding from the California Institute for Regenerative Medicine (CIRM).
NJ First Lady Tammy Murphy headlines a conference with leading health policy experts
Cal State Fullerton antibiotic-resistance researcher María Soledad Ramírez and her students have discovered a promising new therapeutic to treat Acinetobacter baumannii, a superbug commonly found in hospitals and resistant to many antibiotics.
Diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients’ barriers to medication adherence.
New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with Omicron subvariants.
Most contraceptive pills are based on a cycle of taking the pill for 21 days, and then stopping the pill for 7 days. Now researchers have found that women’s mood worsens during the 7 pill-free days. This work will be presented at the ECNP congress in Barcelona on 8th October, after recent publication (see notes).
Multi-institutional effort aims to develop technology to transform diagnosis, treatment of bacterial infections
The American Neuromuscular Foundation is excited to share that Michael Skolka, MD, has received the 2023 Golseth Young Investigator Award for his abstract titled, “The Utility of Electrodiagnostic Testing in Rhabdomyolysis in the Era of Next Generation Sequencing.”
Below are some of the latest headlines in the Women's Health channel on Newswise.
The American Society for Radiation Oncology (ASTRO) today announced the three winning research proposals for the 2022 ASTRO-Myovant Sciences (now known as Sumitomo Pharma)-Pfizer Alliance New Combination (Relugolix-Radiation) Therapy Challenge.
Michael F. Murray, MD, Professor of Medicine at the Icahn School of Medicine at Mount Sinai, has been named the new System Chief of the Division of Genomic Medicine and the Clinical Director of the Institute for Genomic Health at Mount Sinai.