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Harvard Medical School, Sanford Research, Personal Genetics Education Project, Sanford Program, Midwest Initiative in Science Exploration, Promise, Genetics, Developments in Genetics, arc, Awareness Respect and Confidence, Genetic Technologies, Genomes

Harvard Medical School, Sanford Research to Engage Classrooms and Communities Through Genetics

The Harvard Medical School-based Personal Genetics Education Project (pgEd.org) and the Sanford Program for the Midwest Initiative in Science Exploration (PROMISE) at Sanford Research have teamed to bring the latest developments in genetics into classrooms and communities in Massachusetts and South Dakota.

Medicine

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Melanoma, lncRNAs , Skin Cancer, long non-coding RNAs, CRISPR-Cas9, Gene Function, Genomics

Mysterious Molecule’s Function in Skin Cancer Identified

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SBP researcher Ranjan Perera uncovered the M.O. of a mysterious lncRNA molecule called SPRIGHTLY that acts as a hub for cancer-related genes in the nucleus. The study identified “major” RNA binding partners – genes already implicated in a variety of cancers. In a mouse model of melanoma, tumors with reduced SPRIGHTLY grew more slowly, indicating use as a therapeutic target or biomarker. Science Advances.

Medicine

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Neuron, Motor Skills, motor development disabilities, Dyspraxia, developmental coordination disorder, Brain, motor cortex, cortical spinal, Genetics, genes, Cincinnati Children's Hospital Medical Center, Pediatrics, Children, press distribution

Study Suggests Genetic Reason for Impaired Skilled Movements

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Scientists report in Neuron the lost function of two genes prevents infant laboratory mice from developing motor skills as they mature into adults. Researchers also suggest in their study that people with certain motor development disabilities be tested to see if they have mutant forms of the same genes. Their data show that neural circuits between the brain’s motor cortex region and the spinal cord did not properly reorganize in maturing mice lacking the genes.

Medicine

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Genetic Finding May Allow Doctors to Predict Newborn Health During Pregnancy

UCLA scientists have discovered specific genetic changes in the placentas of women who gave birth to growth-restricted infants.

Science

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Biological and Environmental Research, biological and environmental sciences, Synthetic Biology, ACS Synthetic Biology, Joint Genome Institute, Joint Genome Center, Genomics, Software, DNA, Dna Analysis, DNA assembly, Dna Sequence, DNA sequences, Dna Sequencing, DNA sequencing by synthesis, Gene, Gene Discovery, genes, Fuels, Boost, JGI, Biology (Genetics), Bio

New Software Tools Streamline DNA Sequence Design-and-Build Process

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Enhanced software tools will accelerate gene discovery and characterization, vital for new forms of fuel production.

Medicine

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Yale Cancer Center, genome analysis, Gene Sequencing, Human Genome

Gene Sequencing at Yale Finding Personalized Root of Disease

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On Monday, the Yale School of Medicine, partnering with Yale New Haven Hospital, took the next step toward personalized medicine, cutting the ribbon on its Center for Genome Analysis on Yale’s West Campus.

Science

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Wayne State University, Institute of Environmental Health Sciences, Environmental Health, Center for Urban Responses to Environmental Health Stressors, NIH, Niehs, P30 Core Center, Genetics, Epigenetics

Wayne State Receives $7.5 NIH Renewal for Environmental Center

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Wayne State University received notice from the National Institute of Environmental Health Sciences of the National Institutes of Health of the $7.5 million renewal for five years of the Center for Urban Responses to Environmental Stressors (CURES). The previous NIH grant for CURES totaled $2.4 million for three years.

Medicine

Science

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Temple, Temple University, Hospital, Temple Hospital , Gene, Research, Hiv 1, HIV, Animal, Animals

Gene Editing Strategy Eliminates HIV-1 Infection in Live Animals, Temple Researchers Show

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs.

Medicine

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Smoking-Related Heart Disease Tied to Effects of a Single Gene

Smoking counteracts the effect of a gene that normally protects against heart disease, according to a group of researchers.

Medicine

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American Society for Investigative Pathology , Liver, Acetaminophen, Acetaminophen Overdose, acetaminophen induced liver injury, P53, Liver Failure

p53 Critical to Recovering from Acetaminophen Overdose

A new study shows that after an acetaminophen overdose, the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself. The findings could lead to new treatments for people who overdose on this popular pain reliever and fever reducer.







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