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Stem Cells

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Medicine

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Osteomyelitis, MRSA, Mrsa Infections, MRSA strains, MRSA superbug, Stem Cell, stem cell activation, stem cell bio-manufacturing, Stem Cell Development, Scaffold, Scaffold Proteins, Scaffolding, Scaffolds, Bone Infections, Bone Regeneration, silver ions, Silver

A Silver Bullet Against MRSA: Silver Ion-Coated Medical Devices Could Fight MRSA While Creating New Bone

The rise of MRSA infections is limiting the treatment options for physicians and surgeons. Now, an international team of researchers, led by Elizabeth Loboa, dean of the University of Missouri College of Engineering, has used silver ion-coated scaffolds, or biomaterials that are created to hold stem cells, which slow the spread of or kill MRSA while regenerating new bone. Scientists feel that the biodegradable and biocompatible scaffolds could be the first step in the fight against MRSA in patients.

Medicine

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Organoids, Miller-Dieker Syndrome , Brain Development, Lissencephaly, Stem Cells

Human Brain ‘Organoids’ Offer New Insight into Rare Developmental Disease

Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of Miller-Dieker Syndrome (MDS), a rare genetic disorder that causes fatal brain malformations.

Medicine

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Stem Cells, bone, Cells, mice, Biotechnology, Biomedical Engineering

UW Scientists Find Key Cues to Regulate Bone-Building Cells

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The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.

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'Mini-Guts' Offer Clues to Pediatric GI Illness

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Using immature stem cells to create a miniature model of the gut in the laboratory, researchers at Washington University School of Medicine in St. Louis and the University of Pittsburgh have determined how infection-causing enteroviruses enter the intestine.

Medicine

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Cystic Fibrosis, stem cell clinical trials , Mesenchymal Stem Cells

University Hospitals Rainbow Babies & Children’s Hospital Opens First Stem Cell Study in Patients with Cystic Fibrosis

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News release about the first person enrolled in the first stem cell trial for cystic fibrosis.

Medicine

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Glaucoma, Ophthalmology, Biology, Exosomes, Stem Cells, retinal ganglion cell, Bone Marrow Stem Cells, Blindness, Microrna

Stem Cell Secretions May Protect Against Glaucoma

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A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye. The findings, published in Stem Cells Translational Medicine, point to potential therapies for glaucoma, a leading cause of blindness in the United States. The study was conducted by researchers at the National Eye Institute (NEI), part of the National Institutes of Health.

Medicine

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Chulan Kwon, heart muscle, Stem Cells, Rat, rrhythmogenic right ventricular cardiomyopathy, Arvc

Mature Heart Muscle Cells Created in the Laboratory From Stem Cells

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Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists.

Medicine

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Biomedical Engineering, Myocardial Infarction, Heart Attack, Cell Therapy, Stem Cell, human induced pluripotent stem cells

Tissue Engineering Advance Reduces Heart Failure in Model of Heart Attack

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Cardiac muscle patches in this proof-of-concept research may represent an important step toward the clinical use of 3-D-printing technology, as researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold made with a 3-D printer.

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Researchers Discover BRCA1 Gene Is Key for Blood Forming Stem Cells

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Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia. The stem cells die before they have an opportunity to transform into a blood cancer.

Medicine

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Stem Cells, Immunotherapy, Cancer, zika virus, Infectious Diseases, Pregnancy, Public Health, Pediatrics, Neurology, Natural Killer Cells

CIRM Approves New Funding to UC San Diego Researchers Fighting Zika Virus and Cancer

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The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer (NK) cells to target ovarian cancer and other malignancies.







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