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Top Stories 5-17-2016

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Top Stories 5-16-2016

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Top Stories 5-13-2016

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Depressed Moms Not ‘in Sync’ with Their Kids, Children with ADHD Sleep Both Poorly and Less, Yeast Infection Linked to Mental Illness, and more in the Mental Health News Source

Depressed Moms Not ‘in Sync’ with Their Kids, Children with ADHD Sleep Both Poorly and Less, Yeast Infection Linked to Mental Illness, and more in the Mental Health News Source

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Top Stories 5-11-2016

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Top Stories 5-10-2016

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Glioblastoma, Brain Cancer, Neurology, Neurobiology, Surgery, Radiology and imaging, Personalized Medicine

Clinical Study Suggests the Origin of Glioblastoma Subtypes

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Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to different types of brain malignancies.

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Vitamins May Protect Against Nerve Damage in Breast Cancer Treatment, and more Cancer News in the Newswise Channels

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Ulrike Peters, Riki Peters, Colorecal, Precision Medicine, Precision Prevention, Fred Hutch

Precision Prevention of Colorectal Cancer

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Precision medicine’s public face is that of disease — and better treatments for that disease through targeted therapies. But precision medicine has an unsung partner that could affect the lives of many more people: Precision prevention — a reflection of the growing realization that preventing cancer and other diseases may not be one-size-fits-all.

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Pancreas Cancer, Pancreatic Cancer, Sunil Hingorani, Phil Greenberg, Ingunn Stromnes, T Cells, Fred Hutch, AACR 2016

Engineering T Cells to Treat Pancreatic Cancer

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Dr. Sunil Hingorani, a member of the Clinical Research and Public Health Sciences divisions at Fred Hutchinson Cancer Research Center, will present recent groundbreaking developments in treating pancreas cancer with engineered T-cells at the American Association for Cancer Research Annual Meeting 2016 in New Orleans on April 16.

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Precision Medicine, personalized health, Personalized Medicine, common immune variable immunodeficiency disorder, Immune B Cells, Genetics, Ikaros

Within Six Families, a Path to Personalized Treatment for an Immune Disorder

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The most common immune disorder, common variable immunodeficiency disorder (CVID), is notoriously difficult to diagnose early, before serious complications develop. Genetic analysis of six families from across the U.S. and Europe has revealed that mutations in IKAROS, known for its central role in immune cell development, define a new class of CVID. Published in the New England Journal of Medicine, the results open the door to personalized health care tailored to patients with this disorder.

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Chemistry/Physics/Materials Sciences (Nanotechnology/Micromachines), Medicine/Health (Cardiology)

A nanoparticle does double duty, imaging and treating atherosclerosis

Atherosclerosis, a disease in which plaque builds up inside arteries, is a prolific and invisible killer, but it may soon lose its ability to hide in the body. Scientists have developed a nanoparticle that mimics high-density lipoprotein. It can simultaneously light up and treat atherosclerotic plaques that clog arteries, which could someday help prevent heart attacks and strokes. The researchers present their findings at the 251st National Meeting & Exposition of the American Chemical Society.

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Colorectal Cancer, APC gene, NLR

UNC Researchers Discover Colorectal Cancer Biomarker, Potential Personalized Treatment

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In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.

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Cancer, Cancer Care

ASCO to Hold Capitol Hill Briefing March 15 on The State of Cancer Care in America: 2016

The State of Cancer Care in America: 2016 report, to be released on March 15 by the American Society of Clinical Oncology (ASCO), chronicles the current realities of the cancer care delivery system in the United States and examines trends in the oncology workforce and practice environment that are affecting patient care and access.

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iPSC, Human IPCS, Induced Pluripotent Stem Cells, Stem Cells, Embryonic Stem Cells, Regenerative Medicine, Transplantation Medicine

Novel Reprogramming Factor Yields More Efficient Induction of Human Pluripotent Stem Cells

Kejin Hu, Ph.D., has found a robust reprogramming factor that increases the efficiency of creating human induced pluripotent stem cells (HiPSCs) from skin fibroblasts more than 20-fold, speeds the reprogramming time by several days and enhances the quality of reprogramming.

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Genetic Footprints of Heart Disease, Steps to Better Heart Health, Transforming Common Cell to Master Heart Cell, and more in Newswise's Heart Disease News Source

Get the latest news on heart disease, the leading cause of death for people of most ethnicities in the U.S., in the Newswise Heart Disease news source.

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Cancer, Guatemala, Latin America, Maya, Healers, ASCO

Maya Healers’ Conception of Cancer May Help Bridge Gap in Multicultural Settings Care

Understanding and integrating patients’ cultural beliefs into cancer treatment plans may help improve their acceptance of and adherence to treatment in multicultural settings. Researchers examined traditional Maya healers’ understanding of cancer and published their findings online today in the Journal of Global Oncology.

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Melanoma, Skin Cancer, Precision Medicine, Targeted Therapies, BRAF inhibitor , MET amplification, Philadelphia, The Wistar Institute

Blocking Melanoma’s Escape: How Personalized Trials in Avatars Break Therapy Resistance in Relapsed Cancers

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By utilizing a revolutionary method that allows mice to serve as “avatars” for patients, scientists at The Wistar Institute have shown that a previously ineffective targeted drug for melanoma may actually be quite potent in halting the progression of disease in certain patients.

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Nyu Langone, Eduardo Rodriguez, face transplant, First Responder, Organ Donation

Surgeons at NYU Langone Medical Center Perform the Most Extensive Face Transplant to Date – and First in New York State

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NYU Langone Medical Center announced today the successful completion of the most extensive face transplant to date, setting new standards of care in this emerging field. Equally important, for the first time a face transplant has been performed on a first responder – a volunteer firefighter who suffered a full face and scalp burn in the line of duty.

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Chemo Crosses Blood-Brain Barrier with Sound Waves; Virtual Press Conference

Principal Investigator Takes Questions and Demonstrates Procedure with Video and Animation via Virtual Press Conference Tuesday, November 10th at 1:00 p.m. ET







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